Asph038320.1
Basic Information
- Insect
- Asteroscopus sphinx
- Gene Symbol
- -
- Assembly
- GCA_949699075.1
- Location
- OX453030.1:8768869-8784166[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.029 3.5 9.5 1.1 1 23 236 258 236 258 0.96 2 16 0.33 39 6.2 0.1 2 23 287 309 286 309 0.93 3 16 0.61 72 5.4 0.2 3 23 331 352 329 352 0.90 4 16 0.00036 0.043 15.5 2.6 2 23 358 380 357 380 0.95 5 16 0.0028 0.33 12.7 0.8 1 23 385 408 385 408 0.96 6 16 0.43 51 5.9 0.4 2 23 411 433 410 433 0.94 7 16 0.064 7.5 8.5 2.1 2 21 440 459 439 460 0.93 8 16 0.0055 0.64 11.8 0.5 1 23 520 543 520 543 0.93 9 16 0.17 20 7.1 0.3 3 23 572 593 570 593 0.94 10 16 0.054 6.3 8.7 0.2 2 23 616 639 615 639 0.94 11 16 0.0006 0.07 14.9 0.6 3 20 646 663 644 667 0.90 12 16 0.0047 0.56 12.0 0.3 1 23 672 695 672 695 0.98 13 16 0.00094 0.11 14.2 0.4 2 23 701 723 701 723 0.94 14 16 0.00013 0.016 16.9 4.8 1 23 727 750 727 750 0.97 15 16 0.00019 0.022 16.4 0.6 2 23 757 778 756 778 0.96 16 16 0.0053 0.63 11.9 2.3 1 23 784 806 784 806 0.97
Sequence Information
- Coding Sequence
- ATGGAGTTTGACGAGATTGTGGTGAAGGAGAGCCCGGGGCTTTGCCGGTGCTGTCTTTCGGAAGGATGCTACAAGGATCTCGGCTCGGAGTATACTTGGATGAATGATACAGAGGTCTACGCCGATATGCTTCTAGAATGCTTCGATATTAGTATAACCAAACACAATGATGGTCCGAATGGTCCGAACCGACTCATCTGTGAGGTCTGCATCACCCGGCTCCGAGATGCGTGCAACTTCAAGAAGCAAGTGCTGGACTCTGAGAAGAAATTCATTGATATGATGGGCAGGGGGGAGTTTCGGCCGAAGATGCTGATCTACCAGGCGCAGATGAAGTGTGAGGATACAGCGGAGCCGGCCACCGACGACGGTAACGTGGAGTACCTTGAAGAGAATATCGACTTTGGTGATGACGAGCTAAAAGACGAATCAACAGTCCAATCCGTGTCTGACATCACTGTCACTGTCACCGCTCTCCCCATGAAGGGCAAGCGTGGCCGACCTCGTAAGAACGCGCTCGTCAAGCCGGAGAAACGCGTCAAAGCCGCTAAAGCCGAAGATAAGGCGAAGACTTCGAAAGCCGTTTCTAAAGGTATTAAACCGAGGAAATTCAAGGGCTCAGAATCTTCCTCGATGCGGAGACGACGAAACCTCCAAATTATATTCAACAACACATCTATAATCCCTTTTAAATGGCGCGGAAAGTATCTCTGTTTTTATTGCAGTAAAGATATTGCAGAGTATTCAGAGTTGAGGAAACATACGAAATCTCATGGCAATTGTTCCATAAAGGACCATTCGCTCAAAGTCTTAAAAGGTGGACAGAATATGGAAATTAAGATAGATATCTCTGATATATCTTGTGAGGTCTGTTCTGAACCCTTCATGTCTTTCGACGAAGTGATCACACATTTATATGTCAAACATAAGTTAGAGTATGATAGAAGCGTAGAAATGGCTATAGAAGAATATAAGTTAATTGATCTCAGCTGTATAGGATGCGAAGAAAAATTCTCATATTTCGGTTACCTAGTCTCCCATGTCAATAATAATCATCCGAAAAATTGTCTCATCTGTGATAAGTGTAATCagaaattcaacaaaaaacGGGACCTGTTTTCTCACATGAAAAATTATCATCGAGAAGGAGGGTATCAATGCGAAATGTGCCCGCAGGTCTTCAACTCATTGAATATACTAAGAAAACACAGAAATAATAGGCATTTGACTCGATGTAATATCTGCCATTTAAAACTACCCTCAGCGgttttgaaacaaaaacatatCGATATAGAACACCCAGATGACGGGTCCTTACAATGCGATACATGTTTTAAAGAATTCCACACAAAACAAGGCCTCAGAATGCACAATAGAAAATGCAAAGGAGAAGACATCTTCGAAATTTCAATCAAGAAAGAAGAATATGTTGCTATGGATTTAGATCAGAATTATGACGATCAAACGAAAAAACCAAGTGTCAAACAAATCAGAGAAAATATAGTTATAGTAATTAATATGTCTACGGCAATACCTTTTAATTTTTACAAGAATAAGTTCAATTGTTTCTATTGTTCTAAAGATTTTCCTGACTCAGATTTGATGAGGGAACACACGGTTATGGAACATCCTGTATGTGACGTCAAGCAGAAATGTATTAGAAAATGTAGGGAGTCAGTCGCTTGTGTCAAAATCGATGTTTCGTCACTCGCTTGTAAGGTTTGCTTTGAGTCAATGACGGATTTAGACCATTTACTTGACCATTTGATTGTAAAACATGATGCTAATTACGATAAATCGATTACAACGTGTTTGCAGCCTTATCGACTGATCAAAGACCATATGGTCTGCCCAAACTGTCCAGGCGAAGTATTTCGATTCTTCGGAACTTTACTCAAACATATGAACAATAAGCATACGAACAACAATATTATTTGCGTATACTGTGGTCAAACATTTCGTAGGGATCAGAATTTACGTGTCCATATCTGGAGACATCATAGAGATGGGAGATTTAAATGTAATATCTGTGGCGCTGAGTGTAATATTCCTTCTCGATTATACATGCATATGGCTACAGCTCACGGTGTTAAAGCGGCGAAATGTCCCAAATGCTCAGAATCTTTCGCTACTCAATATTTAAGACAGAAACACTTAATTGAGGTCCACGATTCCGGCCACAAATGCACTTACTGCGGGAAACTGTTTACTAGAAATTCGTTCATGAGGGACCATGTAAGGCGGACACATTTGAAAGAGAAAAATGTAGAATGTTCGATATGCAATATGAAGTTCTTTAACAATATTCTTTTGAGAAGGCATATGGTAAAGCATAGTGGAGAGAAGAACTTTCACTGCGATGTTTGTGGCGAAAGATTTTTCTGGAGAAAGAGTCTTAGGACGCATATGGCTAGACATAATAAACATCTTAATCCTGCACAAATTCAATAA
- Protein Sequence
- MEFDEIVVKESPGLCRCCLSEGCYKDLGSEYTWMNDTEVYADMLLECFDISITKHNDGPNGPNRLICEVCITRLRDACNFKKQVLDSEKKFIDMMGRGEFRPKMLIYQAQMKCEDTAEPATDDGNVEYLEENIDFGDDELKDESTVQSVSDITVTVTALPMKGKRGRPRKNALVKPEKRVKAAKAEDKAKTSKAVSKGIKPRKFKGSESSSMRRRRNLQIIFNNTSIIPFKWRGKYLCFYCSKDIAEYSELRKHTKSHGNCSIKDHSLKVLKGGQNMEIKIDISDISCEVCSEPFMSFDEVITHLYVKHKLEYDRSVEMAIEEYKLIDLSCIGCEEKFSYFGYLVSHVNNNHPKNCLICDKCNQKFNKKRDLFSHMKNYHREGGYQCEMCPQVFNSLNILRKHRNNRHLTRCNICHLKLPSAVLKQKHIDIEHPDDGSLQCDTCFKEFHTKQGLRMHNRKCKGEDIFEISIKKEEYVAMDLDQNYDDQTKKPSVKQIRENIVIVINMSTAIPFNFYKNKFNCFYCSKDFPDSDLMREHTVMEHPVCDVKQKCIRKCRESVACVKIDVSSLACKVCFESMTDLDHLLDHLIVKHDANYDKSITTCLQPYRLIKDHMVCPNCPGEVFRFFGTLLKHMNNKHTNNNIICVYCGQTFRRDQNLRVHIWRHHRDGRFKCNICGAECNIPSRLYMHMATAHGVKAAKCPKCSESFATQYLRQKHLIEVHDSGHKCTYCGKLFTRNSFMRDHVRRTHLKEKNVECSICNMKFFNNILLRRHMVKHSGEKNFHCDVCGERFFWRKSLRTHMARHNKHLNPAQIQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00013343;
- 90% Identity
- iTF_00785433;
- 80% Identity
- -