Basic Information

Insect: Asteroscopus sphinx
Gene Symbol: Bcl11a
Assembly: GCA_949699075.1
Location: OX453016.1:24313979-24325436[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.014 1.6 10.6 5.0 1 23 293 315 293 315 0.97

2 12 8.7e-06 0.001 20.6 1.9 2 23 323 344 322 344 0.96

3 12 0.086 10 8.1 0.4 1 23 348 370 348 370 0.97

4 12 4e-05 0.0047 18.6 2.5 1 23 375 398 375 398 0.97

5 12 0.00033 0.038 15.7 0.2 3 23 404 425 403 425 0.96

6 12 0.0081 0.96 11.3 0.2 3 20 441 458 440 464 0.92

7 12 0.0001 0.012 17.3 0.4 3 23 474 495 474 495 0.96

8 12 0.6 70 5.4 0.3 3 23 516 537 515 537 0.95

9 12 0.0032 0.38 12.6 2.7 2 23 549 570 548 570 0.96

10 12 5.1e-05 0.006 18.2 2.8 1 23 576 598 576 598 0.99

11 12 5.3e-07 6.3e-05 24.5 0.4 1 23 604 626 604 626 0.98

12 12 0.001 0.12 14.2 1.5 1 23 632 655 632 655 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.014	1.6	10.6	5.0	1	23	293	315	293	315	0.97
2	12	8.7e-06	0.001	20.6	1.9	2	23	323	344	322	344	0.96
3	12	0.086	10	8.1	0.4	1	23	348	370	348	370	0.97
4	12	4e-05	0.0047	18.6	2.5	1	23	375	398	375	398	0.97
5	12	0.00033	0.038	15.7	0.2	3	23	404	425	403	425	0.96
6	12	0.0081	0.96	11.3	0.2	3	20	441	458	440	464	0.92
7	12	0.0001	0.012	17.3	0.4	3	23	474	495	474	495	0.96
8	12	0.6	70	5.4	0.3	3	23	516	537	515	537	0.95
9	12	0.0032	0.38	12.6	2.7	2	23	549	570	548	570	0.96
10	12	5.1e-05	0.006	18.2	2.8	1	23	576	598	576	598	0.99
11	12	5.3e-07	6.3e-05	24.5	0.4	1	23	604	626	604	626	0.98
12	12	0.001	0.12	14.2	1.5	1	23	632	655	632	655	0.98

Sequence Information

Coding Sequence: atgGGAGACCTAAAAGTATGCCGTATTTGTTTAAATATGGATGTAAAAATGTTCGACATGCAGGCGTATCCTTTAGAATCATATTTTGCTTCGATCGTGGTAGAAAGTAAGTATCTATGCAATAATTTGCCGCCATACGCTTGCTACGAGTGTGCAGCACTTGtgaagaaattttatttattcagacaaAAATGTCTACGCAGCCAAGCTCTTCTATGTAGAATAATAGATGACTGTGGAGAGTTAACACCAGCAGCAATCAAATCAATTGATCGACAAAGTTTCCTAATAGTAACCAACCTCACACATATCAATATAGAACAAGAAAATGTAACAAATAGTACTAATGATGAAGAGAGACCAGAATTTGTGGTGgaagttattaaaaaagaaGATCATGATGACATTGATATTCCTGAGAACATTCCCGATGGGTCTAGCAGTGATGATGAATGTGAAGATAAGAAAGttaagaagaaagtaaaaaatgTAGAGGTTGAAAAATTTGAGATTAGTAAAGATAAGAAGAAAGTTAAAGAATTTGAGTTAGAGAAAGTGAAGATTCTTGTGAAGATGGACATTCAGGAGGAGTTAGATGGATCTAATATTGCAGAAATCACAATAGATGCACCAAAATTACCACCCAAGGCATCCAAGAGGAGGACTCGGGCAGCCCAGGTGAAAAAGCGAAGCAGGCCTCAAAGGACTGGTACAACTGTTGCTCAGAAGAAGCCAAAGAAAGTTATAAAAGATGATAGCCCACGTGTTGAGGATACAACTTATATGGAAGACATAACTGTTGTTACTCTGTCGATGGAGCAGCAACTGGAGGAGGTGAACAAGCGCAAGCAGTCGTCCAACTACCTGAACTGCCCGTACCAGTGTCACCTGTGCTACAGGGGATTCAATAATGCGCAGACGTGGAAACATCACGTCACCAAACACTCTTCGAGCATCGGCGACATAGAGTGCACAATCTGCAAGTACAGGTTTAAAACGAAGCGAAACCTTCAGCGGCACGCGCAGAACCACGGGAGGAGATATGTCTGTAAGCTATGTCCATACAACTCGAGTAATATAACCACAGTGAAGCAACATCAAGGATCGCACAAAGGAGTCACACATAAATGCAACTATTGTGATGAAGTCTTCACTGTGAGAACAACGTACGTGAGTCACATGCGTATCAAGCATCCTTCAGAGAACATCTGCGGCTACTGCGGGTACTCGTTTTACAGCAAGCAGGGCCTTCTCGTACACAAGAATATGGTGCATAGGGATATTGTGGTAAAAGATGAGGAGAATAAAGATGGTCCGTACTGCGCCGATTGTGACGTCAAGTTTATATCAACAGAGGCGTTCAAGCGACACATGGTGATGAGTGTGAAGCACACCAGGAGTACAGACTCTATTAAAGGCTGTCGTGTATGCGGCGAGACGTTCGCGGACTCTGAAGATTTGCGCGTCCATCACCGCGAGGAGCACCCCAAGAGACAGCCCAAACACCACCGCCCCAAGGCGCCGCGCAGCAGGTGGCCCGCCAACTGCAAATATTGTTCAGAAGAGATCTCAAGCGCGCGCGCATACTCGCAGCACTTCCGTCTCGTGCACCCTGATAAGAACTACCCCATTCAGAAGAAATGCGTCTGCGAGATATGCGGGAAGCGATTCGTGTGTAACGCCCTCCTAGTAATGCACAAACGTACGCACTTCGGCGAGCGTCCATACAAATGCTCTGAGTGTGACAAGGCTTGCTTCACTGCCTTCGACCTGCGCGTGCACCAGCAGAAACACTCCGAAGTTAGGCCCTTCCCCTGCAGCGTGTGCTCCAAAGCCTTCAAGCGGAAAGAAGCGCTGGAAAGACATTTGAAGATTCACTCTGGCGACAATCTATACAAATGTGAGATATGTGGAGTAGCATTCAACAAGTCTTGTACGAGAACGCTTCACGTACGCACAGTACATACTAAGGAACCCGCGCCGCCTCGCAAGCGACGGAACAAGACTAACAagtaa
Protein Sequence: MGDLKVCRICLNMDVKMFDMQAYPLESYFASIVVESKYLCNNLPPYACYECAALVKKFYLFRQKCLRSQALLCRIIDDCGELTPAAIKSIDRQSFLIVTNLTHINIEQENVTNSTNDEERPEFVVEVIKKEDHDDIDIPENIPDGSSSDDECEDKKVKKKVKNVEVEKFEISKDKKKVKEFELEKVKILVKMDIQEELDGSNIAEITIDAPKLPPKASKRRTRAAQVKKRSRPQRTGTTVAQKKPKKVIKDDSPRVEDTTYMEDITVVTLSMEQQLEEVNKRKQSSNYLNCPYQCHLCYRGFNNAQTWKHHVTKHSSSIGDIECTICKYRFKTKRNLQRHAQNHGRRYVCKLCPYNSSNITTVKQHQGSHKGVTHKCNYCDEVFTVRTTYVSHMRIKHPSENICGYCGYSFYSKQGLLVHKNMVHRDIVVKDEENKDGPYCADCDVKFISTEAFKRHMVMSVKHTRSTDSIKGCRVCGETFADSEDLRVHHREEHPKRQPKHHRPKAPRSRWPANCKYCSEEISSARAYSQHFRLVHPDKNYPIQKKCVCEICGKRFVCNALLVMHKRTHFGERPYKCSECDKACFTAFDLRVHQQKHSEVRPFPCSVCSKAFKRKEALERHLKIHSGDNLYKCEICGVAFNKSCTRTLHVRTVHTKEPAPPRKRRNKTNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00072266;
90% Identity: -
80% Identity: -