g4368.t1
Basic Information
- Insect
- Amphipyra tragopoginis
- Gene Symbol
- Bcl11a
- Assembly
- GCA_905220435.1
- Location
- HG992003.1:24098941-24113811[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0025 0.16 11.5 3.9 1 23 272 294 272 294 0.97 2 12 3.7e-06 0.00023 20.4 1.6 2 23 302 323 301 323 0.95 3 12 0.029 1.9 8.1 0.4 1 23 327 349 327 349 0.97 4 12 1.4e-05 0.00088 18.6 2.5 1 23 354 377 354 377 0.97 5 12 0.00011 0.0071 15.7 0.2 3 23 383 404 382 404 0.96 6 12 0.004 0.26 10.8 0.2 3 20 420 437 419 443 0.92 7 12 3.9e-05 0.0025 17.1 0.4 3 23 453 474 453 474 0.96 8 12 0.44 28 4.4 1.6 3 23 495 516 494 516 0.95 9 12 0.0052 0.33 10.5 3.3 2 23 528 549 527 549 0.96 10 12 2.6e-05 0.0017 17.7 3.3 1 23 555 577 555 577 0.99 11 12 1.8e-07 1.2e-05 24.5 0.4 1 23 583 605 583 605 0.98 12 12 0.00034 0.022 14.2 1.5 1 23 611 634 611 634 0.98
Sequence Information
- Coding Sequence
- ATGGAAGACGTGAAAGTGTGCCGTATTTGTTTAAATATGGATGTAAAAATGCACGATCTGCAGGCATATCCTTTGGGATCATATTTTACGTCAATCATATTAGAAAGTAAGcCTCTGTGCAAAGACTTGCCGCCTTATGCTTGCTATGAATGTGCAGCACTtgtgaagaagttttatttatttagacagAAGTGTCTGCGGAGCCAGGCCCTGCTATGTGGAATAATAGATGATTGTGGAGAGTTAATGCCAGCAGCAATAAAATCAATTGACAGACAAAGTCTCCTCACAGTATCAAACCTCACACATGTTGATATAGAACCACAGAATGGCACAAATTGTCCTAACGAAGAACAACCGGAATTCGCCGTGCaagttataaaaaaagaagatcATGATGATATTGACGCTCCAGACAACGTCCCCGATCACGGATctagtgatgatgatgaatgtaaAGAGAAGAAGGATAAAAAGAAAATTCAGGATGCTGATTTAGAGAAGGTGGAAGTTCTTGTGAAAATGGATGTTCAGGAGGAGTTGGATGGCCCTGAACTTGCCGAAATCACAGTCGATGCACCCAAATTACCGCCTAAAAAAATTCGGACAGCTCAGCCAAAGAAGCGTAGCAGGCCTAGAAGCACTGGAAAAACAGTTGCTAAGAAGAAGCCGAGGAAAGCCACCAAAGAAGATGGCCCGTGCAGTGACGACAAGACTGACATGGAAGACATCACGGTGGTTATTTTGTCGATAGAGCAGCAGTTAGAAGAAATAAACAAACGCAAGCAGTCTTCCAACTACCTGAACTGTCCGTACCAGTGTCACCTGTGCTACAGGGGGTTCAATAAcgcgcaagcttggaaacatcACGTCACCAAACATTCTGCGAGCATCGGCGATATAGAGTGTACAATCTGCAAATACAGGTTTAAAACGAAGCGCAATCTTCAGAGACACGCGCTAAACCACGGGAAGAAATATGTCTGTAAATTATGTCCATACAACTCGAGTAACATAACCACGGTTAAGCAACATCAAGGATCGCATAAAGGAATCACACACAAATGCAACTATTGTGATGAAGTCTTCACTGTAAGAACAACATACGTGAGTCATATGCGCATTAAACATCCCTCTGAGAACATCTGCGGGTACTGCGGGTACTCGTTCTACAGCAAACAGGGTCTCCTCGTACACAAGAATATGGTGCATAAAGATATTTCGGTAAAAGCTGAAGAGAACAAAGAAGGTCCGTACTGCGCGGAGTGTGACGTCAAGTTTATATCTACTGAAGCCTTCAAACGACACATGGTGATGTCCATCAAACACACAAGGAGTACAGACTCTATTAAAGGGTGTAGAGTGTGTGGGGAAACGTTTGCGGACTCCGAAGAGTTACGTGTGCATCATCGCGAGGAGCACCCCAAGAGACAACCCAAACATCATCGCTCTAAGACACCGCGCAACAGGTGGCCCGCCAACTGCAAACATTGTTCAGAAGAGATCACGAGCGCGCGCGCATACTCGCAGCATTTCCGTCTCATGCACCCTGATAAGAACTACCCCGTTCAAAAGAAATGCGTCTGCGAGATTTGTGGCAAACGATTCATGTGCAACGCCCTCCTAGTAATGCACAAACGCACGCACTTCGGTGAGCGCCCGTACAAGTGTTCTCAATGCGACAAGGCTTGCTTCACTCCCTTCGACCTTCGAGTACATCAGCAAAAACACTCCGACATGAGACCGTTCCCTTGCAGCGTGTGTTCTAAAGCTTTCAAGCGGAAAGAAGCGCTTGAGagacatttaaaaATTCACTCTGGCGATAACCCGTATAAGTGCGAGATATGTGGAGTAGCATTCAACAAATCTTGTACCAGAACGCTTCACGTTCGCACCGTACACACCAAAGAACCCGCGCCACCTCGTAAACGAAGGAACAAACTCACCAAGTAA
- Protein Sequence
- MEDVKVCRICLNMDVKMHDLQAYPLGSYFTSIILESKPLCKDLPPYACYECAALVKKFYLFRQKCLRSQALLCGIIDDCGELMPAAIKSIDRQSLLTVSNLTHVDIEPQNGTNCPNEEQPEFAVQVIKKEDHDDIDAPDNVPDHGSSDDDECKEKKDKKKIQDADLEKVEVLVKMDVQEELDGPELAEITVDAPKLPPKKIRTAQPKKRSRPRSTGKTVAKKKPRKATKEDGPCSDDKTDMEDITVVILSIEQQLEEINKRKQSSNYLNCPYQCHLCYRGFNNAQAWKHHVTKHSASIGDIECTICKYRFKTKRNLQRHALNHGKKYVCKLCPYNSSNITTVKQHQGSHKGITHKCNYCDEVFTVRTTYVSHMRIKHPSENICGYCGYSFYSKQGLLVHKNMVHKDISVKAEENKEGPYCAECDVKFISTEAFKRHMVMSIKHTRSTDSIKGCRVCGETFADSEELRVHHREEHPKRQPKHHRSKTPRNRWPANCKHCSEEITSARAYSQHFRLMHPDKNYPVQKKCVCEICGKRFMCNALLVMHKRTHFGERPYKCSQCDKACFTPFDLRVHQQKHSDMRPFPCSVCSKAFKRKEALERHLKIHSGDNPYKCEICGVAFNKSCTRTLHVRTVHTKEPAPPRKRRNKLTK*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00172077;
- 90% Identity
- -
- 80% Identity
- -