Asph018582.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Asteroscopus sphinx
Gene Symbol
mod(mdg4)
Assembly
GCA_949699075.1
Location
OX453013.1:16234706-16236611[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.9e-29 2.8e-26 93.1 0.0 4 104 23 119 20 125 0.92

Sequence Information

Coding Sequence
ATGGACCAACAATTCTCATTGTCCTGGAATAATTTTCACGGGAACCTGACTAAAGGATTCGCCGGTTTATTAGGAAATGGCGAATTTGTCGACGTAACTATTGCCGTCGAAGGCCATTTGTTGCAAGCACATAAAGTAATACTATCAATATGTTCACCTTATTTCAAGAAAATGTTTCAAACGAATCCATGTCAACATCCAATTGTTGTACTAAGAGATGTGACTCACAAAGCCATGAAAGACTTGTTACAATTCATGTACCATGGAGAAGTTAGCGTAAAACGTGAAGATCTCACTAGTTTTATAGGAACTGCAGAAGTTTTGCAAATCAAAGGATTGACAAACAAAGAGACTGAAGAAGATGAAGATAGTGAAAGAGAGCATGATTTACCCAAGAACAGAATAGAAACTCAGAATAATACTCCGGATGCAGAGTCATGTGTGTCAGACACATACGACACTGGCCTCAATGATGAAACAACACAAAACAATGAACTAGAGCTGCTAAAGCAAAGGCAACTCATAGAAAAACTACACAGACTCAGCAACCTAAAAAGAAAATCTAACGAATTTCTCCAAAAAAACTATTTCTCAGATATACTCAACCCAGAAAAAagaccaaaaacaaaagaaaaacctATTTACACGCAGAACAATCAGATATATCAGATCAATAACTATGAGAACTTGAAAAACTTATATGATGACAACCCTGTAGATATTTCTTCATTCAACACTCAATTACAGAAGGCTAACACTGAAGATTTTAATGACAAAAATAAGGACCAATCTCTGTCTGATAATGGAATAGAACTGAAAACAGAATGTGATGACAGTGATATCATAGTAACAGACCCAGCAGTATGTTCCAATCCTAAAAATTATGAATCTCCAAGAGAAGGGAAAAAAGATTTGTCCATACCCATGGAATATCCATCTCCACAAGACAATACCAGCTTGAGTTCGTTATTCATCGACCTTAAAAACTTAGTGAATGGTAAGGTGACTAACAATGCACTGAGAACTAATACAAGTGAGGAGTACACTAGACCGACAATGGAGCACCGTCTCGTAACAATCCCACAAAAGGAAGATGGAAAGAAGAAGTATCCACAGCGTTCATGTCGCCTCTGCTGGAAAATAGGAAGGAGACGGGACACTAGGTTCATGTGCAGTGCATGTGAACTGCCTTTCTGCAAATCACCTTGCTTCGGAATCCACTTTAATGATATACTCAAAGTATCTCAATTGCAAGGGGATTATTATGCAAATTAA
Protein Sequence
MDQQFSLSWNNFHGNLTKGFAGLLGNGEFVDVTIAVEGHLLQAHKVILSICSPYFKKMFQTNPCQHPIVVLRDVTHKAMKDLLQFMYHGEVSVKREDLTSFIGTAEVLQIKGLTNKETEEDEDSEREHDLPKNRIETQNNTPDAESCVSDTYDTGLNDETTQNNELELLKQRQLIEKLHRLSNLKRKSNEFLQKNYFSDILNPEKRPKTKEKPIYTQNNQIYQINNYENLKNLYDDNPVDISSFNTQLQKANTEDFNDKNKDQSLSDNGIELKTECDDSDIIVTDPAVCSNPKNYESPREGKKDLSIPMEYPSPQDNTSLSSLFIDLKNLVNGKVTNNALRTNTSEEYTRPTMEHRLVTIPQKEDGKKKYPQRSCRLCWKIGRRRDTRFMCSACELPFCKSPCFGIHFNDILKVSQLQGDYYAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00924906;
90% Identity
iTF_00001289; iTF_01062953; iTF_01535105; iTF_00374339; iTF_00831363; iTF_01117475; iTF_00041924; iTF_01063876; iTF_00783653; iTF_01363237; iTF_00273734; iTF_01230758; iTF_01527462; iTF_00364167; iTF_00785319; iTF_00784521; iTF_01441225; iTF_00425578; iTF_00851946; iTF_01247242; iTF_01425227; iTF_00809292; iTF_01119500; iTF_01532236; iTF_01533196; iTF_01027469; iTF_00111790; iTF_00274542; iTF_00888398; iTF_00908046; iTF_00043695; iTF_00120655; iTF_00301327; iTF_00772143; iTF_01084399; iTF_01361775; iTF_00040016; iTF_00446352; iTF_00018289; iTF_00685586; iTF_01062002; iTF_01085522; iTF_00973907; iTF_01029395; iTF_01377619; iTF_00300372; iTF_00375444; iTF_01538900; iTF_00050069; iTF_00447381; iTF_01031253; iTF_01440213; iTF_00449302; iTF_00712054; iTF_00952822; iTF_01064790; iTF_01118454; iTF_01526198; iTF_00302264; iTF_00445336; iTF_00850904; iTF_00951960; iTF_00726585; iTF_01026457; iTF_00037946; iTF_01028442; iTF_00810235; iTF_00906299; iTF_00907164; iTF_00036957; iTF_00041022; iTF_00042783; iTF_00237887; iTF_00786111; iTF_01534079; iTF_00147648; iTF_01030368; iTF_00745921; iTF_01094178; iTF_00071623; iTF_01095080; iTF_01093257; iTF_00924906; iTF_00667667; iTF_00758395; iTF_01192843; iTF_00450286; iTF_01340348; iTF_00122542; iTF_00121584; iTF_00123505; iTF_01339058; iTF_00124411; iTF_01285681; iTF_00327186; iTF_00000450; iTF_00383826; iTF_00017464; iTF_00072207; iTF_00622965; iTF_00173199; iTF_00177305; iTF_01221721; iTF_01342333; iTF_00186398; iTF_01487825; iTF_00185438; iTF_00928832;
80% Identity
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