Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0077 77 4.2 0.0 7 21 7 21 5 26 0.89

2 9 0.0085 86 4.1 0.0 7 21 29 43 27 46 0.90

3 9 0.012 1.2e+02 3.7 0.0 7 21 51 65 49 68 0.91

4 9 0.049 5e+02 1.7 0.0 7 21 73 87 71 91 0.89

5 9 0.011 1.1e+02 3.8 0.0 7 21 95 109 93 112 0.91

6 9 0.01 1e+02 3.8 0.0 7 21 117 131 115 134 0.91

7 9 0.59 5.9e+03 -1.8 0.1 10 21 142 153 139 155 0.86

8 9 0.0053 54 4.7 0.0 7 21 161 175 159 180 0.89

9 9 0.038 3.8e+02 2.0 0.0 7 20 183 196 181 199 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0077	77	4.2	0.0	7	21	7	21	5	26	0.89
2	9	0.0085	86	4.1	0.0	7	21	29	43	27	46	0.90
3	9	0.012	1.2e+02	3.7	0.0	7	21	51	65	49	68	0.91
4	9	0.049	5e+02	1.7	0.0	7	21	73	87	71	91	0.89
5	9	0.011	1.1e+02	3.8	0.0	7	21	95	109	93	112	0.91
6	9	0.01	1e+02	3.8	0.0	7	21	117	131	115	134	0.91
7	9	0.59	5.9e+03	-1.8	0.1	10	21	142	153	139	155	0.86
8	9	0.0053	54	4.7	0.0	7	21	161	175	159	180	0.89
9	9	0.038	3.8e+02	2.0	0.0	7	20	183	196	181	199	0.89

Coding Sequence: ATGGTTCAGGTCTTCATCAACCATGGCCCAGGTCTTCATCAACCATGGTCCAGGTCTTCATCAACCATGGACCAGGTCTTCATCGACCATGGTCCAGGTTTTCATCAACCATCGTCCAGGTCTTCATCAACCATAGTCCAGGTCTTCATCAACCATGGTCCAGGTCTTCATCAACCGTGGTCCAGGTCTTCATCAATCATGGTGCAGGTATTCATCAACCATGGTCCAGGTCTTCATCAACCATGGACCAGGTCTTCATCAACCATGGTGCAGGTCTTCATCAACCATGGTCCAGGTTTTCATCAACCATGGTCCAGGTCTTCATCAACCCTGGTCCAGGTCTTCATCAACCATGGACCAGGTTTTCATCGACCATGGTCCAGGTCTTCATCAATCATGGTCCAGGTATTCATCAACCCTGGTCCAGGTCTTCATCAACCATGGGCCAGGTCTTCATCAACCATGGTCCAGGTTTTCATCAACCATGGTCCAGGTATTCATCAACCCTGGTCCAGGTCTTCATCAACCATGGACCAGGTCTTCATCAACCATGGTCCAGGTCTTCATCAACCATGGTCCAGGTCTTCACCGACCATGGTCCAGGTTTTCATCAACCATGGTCCAAGTCTCAATCAATCCAAGTCTATATGGATCATTCTCCAAATTTGGATCATCCATCCTCTACGTTTGCATGAACCATGCTCCAGGTCTGGATGCATCATGGTCCACCCCAGAATCAATCATCCTCCATCAGGCTACTGGACCAAAATTCTCTGTCCCCCAAATCCTCTACCCGAGCTGGAATCGTCCGCATGCCCTCCCGAGCAATCTGACGTTATCAGCTGCTACTGCTGCAAGGATTGA
Protein Sequence: MVQVFINHGPGLHQPWSRSSSTMDQVFIDHGPGFHQPSSRSSSTIVQVFINHGPGLHQPWSRSSSIMVQVFINHGPGLHQPWTRSSSTMVQVFINHGPGFHQPWSRSSSTLVQVFINHGPGFHRPWSRSSSIMVQVFINPGPGLHQPWARSSSTMVQVFINHGPGIHQPWSRSSSTMDQVFINHGPGLHQPWSRSSPTMVQVFINHGPSLNQSKSIWIILQIWIIHPLRLHEPCSRSGCIMVHPRINHPPSGYWTKILCPPNPLPELESSACPPEQSDVISCYCCKD

Sequence clustering based on sequence similarity using MMseqs2