Basic Information

Gene Symbol
RREB1
Assembly
GCA_017141405.1
Location
JADHZF010000068.1:82333-94748[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0029 0.46 11.8 0.0 1 23 38 60 38 60 0.98
2 16 0.00013 0.021 16.0 0.3 1 23 74 96 74 96 0.98
3 16 2e-07 3.2e-05 24.9 1.1 1 23 102 125 102 125 0.98
4 16 0.41 66 5.0 0.0 1 23 213 237 213 237 0.95
5 16 0.046 7.3 8.0 2.6 2 23 243 265 243 265 0.94
6 16 0.69 1.1e+02 4.3 0.4 1 19 319 337 319 340 0.90
7 16 0.075 12 7.3 0.5 1 23 450 472 450 472 0.97
8 16 0.00011 0.018 16.2 0.2 1 23 481 503 481 503 0.98
9 16 0.0017 0.27 12.5 2.8 1 23 509 532 509 532 0.96
10 16 0.0005 0.079 14.2 2.8 1 23 904 927 904 927 0.96
11 16 0.0005 0.079 14.2 0.1 3 23 1186 1206 1184 1206 0.97
12 16 0.44 71 4.9 6.0 1 23 1212 1235 1212 1235 0.97
13 16 0.0031 0.5 11.7 2.2 1 23 1274 1298 1274 1298 0.97
14 16 7.9 1.3e+03 0.9 4.5 1 23 1386 1408 1386 1409 0.92
15 16 0.0084 1.3 10.3 0.4 2 23 1460 1481 1459 1481 0.94
16 16 0.0029 0.47 11.7 5.5 1 23 1487 1509 1487 1509 0.98

Sequence Information

Coding Sequence
ATGGATTGCTCCAAAAAAGTGACCATCGAGAACGTTCCGGACCAACGACACAATAGTGAAACACAGACCGATGCCGCATCAACTTCATCGGTTGAACAATCGGAGGGATCCTACCCATGTCCCGCATGCCCACTCATCCTAACATCATCACGCGACCTGACAAATCACCTTCGAGGCCACAATTCGCCCCGTAGTACTGACTACAGTGGTGAGGAAGACTACTCTTGTGGTGTATGCCACAAAGTTCTAAGCTCAGCAAGTTCCCTAGATCGTCACGTCCTAGTGCACTCCGGCGAGCGTCCATTTAAGTGCACATATTGCGATATGGCATTCACAACAAATGGTAACATGAATAGACACCTAAGAACGGCGCATCGTGAAGTGTCACCTCACAGTTACACGGATTCTGAGGGTAGCAGTGACTCGGAGAGACCAGTAACGCGGCGACACGTAGACGAGTACAATAATAATGAAATCACCAAACGTAGTTCACCAGACATAATCGATGGTGTATCCCCAAGCTCCAGATCAAAGAGAAAGAAACCAGATTACCCTGATGAAATTGATATCCAAAGAAAGCATAAGATCCTGTTGAACAATGCGAGATTTGATGGAAAGAACATTCTTCCAAGTTCCTATATGTGCCCAGTATGTCCCTCCACAGATTTTCCAACCGCAGCTCTACTCGAAGGTCACTTGGAGCGAGCTCATCCAGATTATACAGCTGAGTGTGATTCCTGCAATAGGTCCTTCAAAAACCATAGAGTCTTAAATCTTCACCGATTTATGGTTCACTTCACCGAAAATTCAACACCACCCAGAAACCTAAGAAACTCGGTAATAGGCTTCAACGATTTAACATTCGTTGATTTCTCAGCTGACAAATTCCCGGCAATTGCAAGAGCAGTGTGCGAACAGTCACTCCATCGTCCAGCATCAGGGGAAAGTGCTACATTCCAATGTTCAAAGTGCTTGCGTGCTTTTCCTTGCAAATCGGCATTAGAGGGGCACGAAATGGACTGTGGAAATATGCATTATCAAGCAACCCGTGTAGATGATGATCACTCGAAGAGAAACGACTTTTTTGCTGGTTTGGATCTACAGAATAAGGCGGCACTGACGGAAGCCAAGGAGGGCAAAGATCTCGCTGATATTCAGAGCATTATTTCCGTGACATCTGGTCCAATATTTCCGCGATCAGACGCCAGTACTCCTGATCAACATATCAAGATGAATCCAAACATTATTTCATCAGGTTCATCAGGCACAGCATCATCAGAAAATACTGAGGAGGAGGCTCAAGATGCATTTTCCGCTGAATTAAGGAAAATGAAGCTCAAGGGTGAATTCCCATGTCGACTGTGCACTGCTATATTTCCGAATTTACGAGCTCTGAAAGGACATCACAAAGAACACATGGGCGTTGCTCCAGGGATGCCATACCCCTGCAATGTTTGCCCCTTTACATCGACCGATAAGGCAGCTCTGAGTCGTCACCTCAAGTCTCACAATGGCGTACGCCCTTATCAGTGCTCTCTTTGCAAATATGCATTTACAACAAAAGCCAATTGCGAGAGACACGTGAAGAATGGCCACAAGATCATGACAAGAGAGGAAATAAAAAGTGTTCTCATTTATCACGCCAATGAGGATGCAGCTAATGAGGGACTTGACAGAACATCGCCAAGATCAATTCGTGATGATGCCCGAAAATCTCTAGTCTATCCCGATCGGGACGAGCTCTCCCAATCACACTTCTTGAACTCAAGACATTCTGATATAATCGCTGAAGAGGTTAGACTAAGACAATTAGCCTCCATGCGTGCCACACCAGTCAGTCATTACGAGAAATCCGATATTTTCTCAAGACCACCACCAATGCACCTGCTGGAGCTATCCCACAGGATATCGGAAGAATCTGATAATCCCCAGGACTTTACGAAATCAAACTATTCTAGAATGGAGGAGGATGATTCAAGATCATCCGATGACAGTGCATCACTAGTCAACGATGCCAAATCCGACGCACACCAAAGAACACTGGCTAGCCCAATTGACCTAAAAAGTACCTCAATGGGTGATGATGCACCATTGGATTTGTCTATGGATGTTCTTGATCTCAGTAAAAAATCAAAGGACAATGGCACTGATTTATCCATGACTGATGACTTTGACAAAAATCAAAAGGACATGTACGAGTCCGCAACAAGTCAGTTCCTACTGACTCAAGCACTCCTCAAAGCCGGACAATCCGGAAACTCACCGAGCTCTCTGGAGGCTCTCTACGCAAATGCTCATCTGCTTTATAGAAACTTTGGTGGATTTTCCGGGGCTGGAGTTGGTGGGGGAATGCTACCACCTTATCTATTCAATCCCCACCTCTTTGGGCAAGACTTTGCCATGCGAGATAGGCTGCAAAAGGAGCTTGTCCGAGGTCTTCAACTAACTAGTGGAGGAACCCTGGTAGAGCCTACACTCAATAACTCAAGTTTCCCATCTCCATATCCTCAAGCAAGGGACCTAACCCCTCGCCCACACGATGATCAAAACGACTACTCCAAGCTTATGGCATCTAAAATCGTCAACAAAGTTGCAAGTCCTCGTGAGAAAATTGAAACAACACCTACATCGAATTCCGTGAAAATGGTCATCAAGAATGGAGTTCTGATGCCTAAACAGAAGCAGAGGAGATACAGGACGGAGAAGCCATTTAGCTGTGAACACTGCTCAGCAAGATTTACTCTCAGAAGCAATATGGAGAGACACATTAAGCAACAGCATCCTCAACATTGGAGTCAACGGCCACGTGGCGGTCACTCCACCCGAGGACGTCCTCCAACAAATCCACCAAATATGCTTCACGCATTGAGCCCTTCCAGCCAACTCCAGCCGTCATACCCCAATATACTCCCAAAAATGGGACAATCTTCAGAGTACGGAAAGCATGCGATTTCCGATCAAGTGAAATACGCAATTCTTGCTCAACAGTTGAAGGGTAACAAGCATGAGGAGAATGACAGTGATGAAGAGTTGATAATTGATGAAGGTGCCGATAAGGAATCAGAGAGCCCAGAGGAAGACAGGCCAATTAGTTTGTTGAGGGGAAAGCTAGAGGAAAGTGCAAAGGATTCTCAGAAAGAATACAATGAACCAAGTTCTGACACCCCAATGGATCAAGATCCCATTGACATGAAGATAAAACCCGACCCAGAGGAGACCAATGACTCACAACTCAAACACTCAGACGATGAGGAAATGCCTGAAACCAAAGTTATTAAAACAGAGGACGGCAACGCCGATCTCGCCAGTGTCTCTGAGCTCCTGGATAACGCATCACAACAATACCAACAATTCCAGCCCCAGTACATGAGCGATGAAGAGGGTCTAGTGGCTTCAACCAGCGACTGCAACAATTCTGGAAGTGATGAAAAATCAGATTCAGTCAACAGTGGCAATTCCGGCCAGTCATCCTCCTCGAAATTGAAAAAACTGAAGAGAAAGAAGAAAAAGAAGAAGAAGAAATCGGCATACTCAATGGCACCAAATCGGGTAATCTGTCCCTACTGCGAGCGTCCCTTTCCCTGGACCTCATCACTGCGACGTCACATTCTAACTCACACAGGCCAGAAGCCCTATCAGTGTGTCCATTGCTCTCTGCTCTTCACAACTAAATCAAATTGCGATCGTCATTTGCTGAGAAAGCACAAAGCCAATCCAAATAAAATACGTAGAATGAGAAACTCATCATCACCTGAGGCTCAAGAAGTACCCACCAACAATAACAGTACATTTTCCATGAGAAATGTACCAGAGCGCCCCTACAAATGCAACCAATGTCCCAGCTCCACATTCTCCACCCTCGGAAACCTGAAAAAGCACCGATCCACCAAACACTCTCACGGAGAAAAATCCAGACCAGAGAGTCCCATGAGCGAGACCCATTCAGAGCGCCAAATCAGTCCTGTACCAACAAGCAAGCAAAACGATCAAAGTGGTTATGAGAGTCAGTCCTCCAGTGTGTCCGAGAATATGGAACAATTACCCACGATTCCTGAAGCTCCCAAATCAAATCTCAACACCTCATCATCAACAAGTGAGACACCAAAATCCAGAAGGCCATCTCCACGAGCATCACCTGGTCCAACCGATGCACCATTCAAGTGTCACCTCTGCGATTCTGGTTTTGCTGAACGTCAGGACTGCTTGGAGCACATAAAGGATCATCACAAACGTTCCTACGAAATGCTGTTGGCCAAAGGTGCTCTGGACATGGACACGGAAAACCCTGAAGAACAACAGCCACCACCATCCCAATCTCATCACAGTGATGGTGAAGAGAAACGCGGCAAATTTCCTGACTACAGCAACAGAAAAGTCGTATGTGCCTTTTGCATGCGTCGCTTTTGGTCAGCTGAAGATCTTCGCCGTCATATGCGAACACACACAGGAGAAAGGCCGTTCTCATGTGATATATGCTCGAGACGTTTCACCCTGAAGCATAGTATGCTTCGTCATCGTAAGAAGCACGAGTCGGTAGATTCAACTATGTATGTGGGTACAAGCGGTGATGAGGAGTCTGTACCCACCCAGCCACCCACAATAACTCCACGAACTCACCAAAATCCTCTCATCTCAGTTGCAAGCTCAGATGCCAGAATTCGGGAACGAATCTCTTTGCCAACTGTCGCGGCAATTGCAACAGGTGATGCAGCCCCCAGCAGTCTGATGAGATTCAATCCATACGAGAAACTAGCAACACTAACAGGTAAACTGGCTAGTCAAAATTTTGGTTCTGATGTAATTGGGGATAACGAGAACGATTTGATATCAAATTTACTTGGTATCAGAGACAAAAGTATCATTGATAAAGTACTGCAAGCTTCTGCTGATGATGCTGCAAAATTGCTTGGTGTTAATAGAAGTCATGAATGA
Protein Sequence
MDCSKKVTIENVPDQRHNSETQTDAASTSSVEQSEGSYPCPACPLILTSSRDLTNHLRGHNSPRSTDYSGEEDYSCGVCHKVLSSASSLDRHVLVHSGERPFKCTYCDMAFTTNGNMNRHLRTAHREVSPHSYTDSEGSSDSERPVTRRHVDEYNNNEITKRSSPDIIDGVSPSSRSKRKKPDYPDEIDIQRKHKILLNNARFDGKNILPSSYMCPVCPSTDFPTAALLEGHLERAHPDYTAECDSCNRSFKNHRVLNLHRFMVHFTENSTPPRNLRNSVIGFNDLTFVDFSADKFPAIARAVCEQSLHRPASGESATFQCSKCLRAFPCKSALEGHEMDCGNMHYQATRVDDDHSKRNDFFAGLDLQNKAALTEAKEGKDLADIQSIISVTSGPIFPRSDASTPDQHIKMNPNIISSGSSGTASSENTEEEAQDAFSAELRKMKLKGEFPCRLCTAIFPNLRALKGHHKEHMGVAPGMPYPCNVCPFTSTDKAALSRHLKSHNGVRPYQCSLCKYAFTTKANCERHVKNGHKIMTREEIKSVLIYHANEDAANEGLDRTSPRSIRDDARKSLVYPDRDELSQSHFLNSRHSDIIAEEVRLRQLASMRATPVSHYEKSDIFSRPPPMHLLELSHRISEESDNPQDFTKSNYSRMEEDDSRSSDDSASLVNDAKSDAHQRTLASPIDLKSTSMGDDAPLDLSMDVLDLSKKSKDNGTDLSMTDDFDKNQKDMYESATSQFLLTQALLKAGQSGNSPSSLEALYANAHLLYRNFGGFSGAGVGGGMLPPYLFNPHLFGQDFAMRDRLQKELVRGLQLTSGGTLVEPTLNNSSFPSPYPQARDLTPRPHDDQNDYSKLMASKIVNKVASPREKIETTPTSNSVKMVIKNGVLMPKQKQRRYRTEKPFSCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPTNPPNMLHALSPSSQLQPSYPNILPKMGQSSEYGKHAISDQVKYAILAQQLKGNKHEENDSDEELIIDEGADKESESPEEDRPISLLRGKLEESAKDSQKEYNEPSSDTPMDQDPIDMKIKPDPEETNDSQLKHSDDEEMPETKVIKTEDGNADLASVSELLDNASQQYQQFQPQYMSDEEGLVASTSDCNNSGSDEKSDSVNSGNSGQSSSSKLKKLKRKKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCVHCSLLFTTKSNCDRHLLRKHKANPNKIRRMRNSSSPEAQEVPTNNNSTFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHSHGEKSRPESPMSETHSERQISPVPTSKQNDQSGYESQSSSVSENMEQLPTIPEAPKSNLNTSSSTSETPKSRRPSPRASPGPTDAPFKCHLCDSGFAERQDCLEHIKDHHKRSYEMLLAKGALDMDTENPEEQQPPPSQSHHSDGEEKRGKFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICSRRFTLKHSMLRHRKKHESVDSTMYVGTSGDEESVPTQPPTITPRTHQNPLISVASSDARIRERISLPTVAAIATGDAAPSSLMRFNPYEKLATLTGKLASQNFGSDVIGDNENDLISNLLGIRDKSIIDKVLQASADDAAKLLGVNRSHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00728833;
90% Identity
-
80% Identity
-