Ajap000298.1
Basic Information
- Insect
- Asobara japonica
- Gene Symbol
- -
- Assembly
- GCA_017141405.1
- Location
- JADHZF010000026.1:2767065-2770636[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.3e-13 4e-09 36.7 0.1 12 73 231 290 223 293 0.86 2 2 0.69 5.2e+03 -2.1 0.0 35 48 440 456 379 459 0.62
Sequence Information
- Coding Sequence
- ATGGAGGTTACTAATGCGAATGGCGGGAACGCTGAGGTGGCGCACACGAAATCTAACCTACAAGGTGTTGTCGAAACAAATCTGAAGATCGGAGTTACTCTTGATCAAGGGAAGTTGAAAGGTAACAAGAAAATGGACGGGGAAGAAGTAAATAGTGGTGATAAAAGTGTTAAAAAAAAGCCGATGAAAAGAAAGATGCGTAAGTCAAAGTCAAATTCTACGAGCAGTGTGGAAACTAATGCCAAACAAAAGGCTAGAGGAGTCAAGAGAAAATTATCGGATCCGTGTAGTTCTAATGATGAGGAATCGCAGGAGTTTCTTGGTTTTTCACCGGAGAGTGTTAACCTAATTGAGACAGAATTGCAAGTTATTCAGAAACTTATTGCTGACGCAGAATTGGAGACGAACTCTTCGAAACGTAAGCGCAGTTCCTCGAAAGCAACTCCAACGAATTTGGAGTCGAAATCAATCGTTGAACATGCTGAAAAAGTGACAATAACTGATGGTAAAACGAATTCCATTAATGTTGATGAAGGACTGAAACAAGAAGATGAAAAAGAAACGGAGAAAAAGGATGCAATTGTTATACCACATGCTTCGAAATCAGTTTCGAATAATGTGAACAGTGAGACCCCTTCAAGTGAAATTCCATCCGTAAACGCATCGAACAACTTGTATAAAGAGCCATTTAAATTTGGTTGGAGGCGTGAGGTGATATACAAGGGTGAAAGCAATAGTGCTCAGAAGAGAATCGCAGACATTTATTATTACTCTCCCAAGGGTAAGAAGGTTAAGAGCCTTCGAGAAGTCGCAGAGTGTTTGACAACAAAGGAGTTAACTTTAGATAATTTTACATTTTCTAAAGAATCCATTGGCGTTGAAGACCCGTCTCTGGAAATGATCACAGATACGAAAAAACCAAGATTAGAGTCAACAAATATTCAGGCTACACCTACAAAAAAATCTTCGAATAAGCGAGCGCCAATGGCTAAAGCGCTACTGACATCACCTCCAGGCTCACCCAAAATCGCTAAGACATCACCACCTAAAGCAACAACACCTGCTAGATTCAAAATTAAAGTCCCTGGAAAACGTGCAATGCAGAAAAAAGAAGTGAAACCATCCAAAGAATCAGAAATGGTGCCGCCCCAGTGGGCTTCTCCAACTGCAACGAGAAGAAGCCAAACAGTCGCTGATAAACTTACATCACCGAAAAATAAGAGGATATTAAAAGCTAAACTCCAGGAGCCCTGCAGTATTCGATGTTCACTGAGTATGGGACTGATACCAAGTCTCCAATGTCGCATTTGTCTATGTTTATATCATCCGGACTGTGTTGGTGGCAAAAAATTATCAACCAACAAGGAATACGTTTGCAAGGTATTATTGATAAGCAAAAATTGA
- Protein Sequence
- MEVTNANGGNAEVAHTKSNLQGVVETNLKIGVTLDQGKLKGNKKMDGEEVNSGDKSVKKKPMKRKMRKSKSNSTSSVETNAKQKARGVKRKLSDPCSSNDEESQEFLGFSPESVNLIETELQVIQKLIADAELETNSSKRKRSSSKATPTNLESKSIVEHAEKVTITDGKTNSINVDEGLKQEDEKETEKKDAIVIPHASKSVSNNVNSETPSSEIPSVNASNNLYKEPFKFGWRREVIYKGESNSAQKRIADIYYYSPKGKKVKSLREVAECLTTKELTLDNFTFSKESIGVEDPSLEMITDTKKPRLESTNIQATPTKKSSNKRAPMAKALLTSPPGSPKIAKTSPPKATTPARFKIKVPGKRAMQKKEVKPSKESEMVPPQWASPTATRRSQTVADKLTSPKNKRILKAKLQEPCSIRCSLSMGLIPSLQCRICLCLYHPDCVGGKKLSTNKEYVCKVLLISKN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -