Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0088 2.6e+02 2.5 0.0 21 46 94 119 91 125 0.83

2 9 0.0027 80 4.2 0.1 23 46 124 147 119 153 0.84

3 9 0.0043 1.3e+02 3.5 0.1 21 31 150 160 142 176 0.81

4 9 2e-05 0.58 11.0 0.0 21 52 178 209 170 211 0.84

5 9 0.0025 74 4.3 0.0 23 52 208 237 202 238 0.86

6 9 0.0087 2.6e+02 2.5 0.0 23 44 236 257 233 261 0.90

7 9 3.4e-06 0.099 13.5 0.1 21 52 262 293 258 294 0.88

8 9 0.0032 94 3.9 0.1 22 46 291 315 286 320 0.86

9 9 0.014 4e+02 1.9 0.1 25 46 322 343 315 348 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0088	2.6e+02	2.5	0.0	21	46	94	119	91	125	0.83
2	9	0.0027	80	4.2	0.1	23	46	124	147	119	153	0.84
3	9	0.0043	1.3e+02	3.5	0.1	21	31	150	160	142	176	0.81
4	9	2e-05	0.58	11.0	0.0	21	52	178	209	170	211	0.84
5	9	0.0025	74	4.3	0.0	23	52	208	237	202	238	0.86
6	9	0.0087	2.6e+02	2.5	0.0	23	44	236	257	233	261	0.90
7	9	3.4e-06	0.099	13.5	0.1	21	52	262	293	258	294	0.88
8	9	0.0032	94	3.9	0.1	22	46	291	315	286	320	0.86
9	9	0.014	4e+02	1.9	0.1	25	46	322	343	315	348	0.85

Coding Sequence: ATGGGCAGTGTAGATTATTCCTCGGACAGCAGCAACTCTTCAGCTGAAGTCGACAGTGGCGCGGGACGCCAAGTGAGTGAGAGTCGGCCGGCGCAGGAGACGGGGGACGGCAGCCTCAGCAAACTGTCTTGTACGCTGTGTCCGTACCAGACGACCAAGGAGCTGCAGCTGGCCAGCCACCTGAAGGCGCACGCTGCCGCGCACTGCTACCGGTGCAACATGTGCAGCTACATCACGGTGCACCGCTACAGCCTCTCCTGCCACTTCAAAATACATACGGGAGAGAAACCTTATTCCTGTGATGTCTGTTCCAAGTCCTTCAACGTCAAGAGCAGCCTCAGAACGCACATGAAGACACACTCTGGTATAAAGCCGCACACATGCGACATTTGTCAGAAAAGATTCACCGAGAAAAGTAGTCTCAAGACACACTTGAAGACACATTCTGGGGAAAAACCATATACATgtgatatttgtaataaaacttttataacgaGGGACAAGTTGAGCATACACTACCGGACGCACTCCGGGGAGAAGCCATATTCGTGCGAGTTCTGTTATAAAACGTTCAGTCAAAAAGGCATTCTGAACCGCCACCTGACCACACACTCCGGGGTAAAGCCATATCTCTGCTACGTCTGCAACAAGACGTTCAACAGAAGCGGGAGTcttaaaatgcacctcaagATACATTTTGGTCAAAAGCCTCATTCTTGCGAGACCTGTCACAAAACCTTCATAGAGAAGAGAGGGCTCACGAGGCACATGATGACGCACACCGGAGAACAGCCGTTCACCTGCGAGATCTGTTTCAAGACGTTCACCCGCCAGTACGGACTGAGGACGCACTGGAGGTTACACTCCGGACAAAAGCCGTATCCGTGTGAcgtctgtaataaaatattcaatcaaaAGTCGCACCTCACCAAGCACATGAGGATCCACACCGGGGAGAAACTGTACTCCTGTCACGTGTGCAGCAAGGCGTTCACGGAGAAATCTAATCTTACCAAACATTTGAGAATACACAAGACGTTCGAGGACACTTACGTGTGA
Protein Sequence: MGSVDYSSDSSNSSAEVDSGAGRQVSESRPAQETGDGSLSKLSCTLCPYQTTKELQLASHLKAHAAAHCYRCNMCSYITVHRYSLSCHFKIHTGEKPYSCDVCSKSFNVKSSLRTHMKTHSGIKPHTCDICQKRFTEKSSLKTHLKTHSGEKPYTCDICNKTFITRDKLSIHYRTHSGEKPYSCEFCYKTFSQKGILNRHLTTHSGVKPYLCYVCNKTFNRSGSLKMHLKIHFGQKPHSCETCHKTFIEKRGLTRHMMTHTGEQPFTCEICFKTFTRQYGLRTHWRLHSGQKPYPCDVCNKIFNQKSHLTKHMRIHTGEKLYSCHVCSKAFTEKSNLTKHLRIHKTFEDTYV

Sequence clustering based on sequence similarity using MMseqs2