Aage019812.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aricia agestis
Gene Symbol
egg
Assembly
GCA_905147365.1
Location
LR990261.1:4196856-4225052[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.8e-13 1.9e-09 37.4 0.0 4 75 1724 1788 1721 1790 0.90
2 2 0.46 2.2e+03 -1.3 0.1 5 18 2148 2161 2145 2167 0.85

Sequence Information

Coding Sequence
ATGACTTCTAAAAGCGACGAAAATACGACAGAAGAATTGTGTGATGAGGCTCTAAATGTTGAGAATGCAGTTGCAACACATTTTGAAGACCAACCAACACCAACCACACATTTGTCTTTTAATTCTGATCTTAAATCTATAAGTGACGATATTGCAGTGCAGTCGATAGAAGAACACTCTGATGATAATATAATATCAATTCAGAATAAAGAATGTGATAATGCAACAAAGGGTGGTGTTAAAAGTCATGATACCGCCGACACAGCTGAAAAAACCATGGCCATACTTGACACATTAATAAACCCTTCTGATTCCATTAACAATGAAATTTCAAATACAATAGAAGTTACAGAAGGTAAAGATGAAACTGCAACAGAAAAACAAGTTTTAGATGATAAAACATCACAACAAAAGCAGGACGATATTGCAATGCAGTTGAAAGAAGAATATTCTGATAATAATATTATATCAATTCAGAATAAAGAATGTGATAATGCAGCAAAGGGTGGTGTTGAAAGTCATGATACTTACACAACTGAAAAAACACAGTCTGATCAGAGACAAGGCAGTAAATCAGAAATCATACTTGACAAATTAATAATCCCCTCTTCAGATTCCATCAACAATAAAATTTCTAATACAATAGAAGTTACAGAAGGTAAAGATCAGACTGCAACAGAAAAACAAGTTTTAGATGACAAAACATCACAACAAAAGCAGGATGATATTGCAATGCAGTCGAAAGAAGAACACTCTGATAATAATATTATATCAATTCAGAATAAAGAATGTGAATATGCAGCAAAGGGTGGTGTTGAAAGTCATGATAATTACACAACTGAAAAAACACAGTCTGATCAGAGACAAGGCAGTAAATCAGACATCATACTTGACACATTAATAAACCCATCTTCTAATTCCATCAACAATAAAATTTCAAATACAATAGAAGTTACAGACGGTAAAGATGAAACTGCAACAGAAAAACAAGTTTTAGATGACAAAACATCACAACAAGAGCAGGACGATATTGCAATGCAGTCGAATGAAGACCACTCTGATAATAATATTATATTAATTCAGAATAAAGAAGGTGATAATGCAACAAAGAGTGGTGTTGAAAGTCATGATACTTACACAACTGAAAAAGCACAGTCCGATCAGGGACAAGGCAGTAAATCAGACATCATACTTGACACATTAATAAACCCATTTTCTGATTCCATCAACAATAAAATTTCAAATACAATAGAAGTTACAAAAGGTAAAGATGAAACTGCAAGAGAAAAACAAGTTTTAGATGACAAAACATCACAACAAGAGCACAATGAGGTATACAATGAAATGGATGTGGATGTATTACCAAACACTAAACGAGAACAAATTATTGTAGGTAAAGCCAATGATGATTCTGTTAAAGTTACTGATGATGCCGATAAAAACCCTGAGTCAGAATTGAAAATGGATGATTATGATGATAGTGATAATATGACAAAACCATCAAGTTATACAGAAAAAGATAAAGAAGATATTTTAGTTCCTTCAAAACCAGAAACTAGCAGTACTGAAACACCTGGCATAGAGCTGGAAAGTAGTTTACAATATGATAATAATGGGGATGATAAATTTAAGCTTGTATGGGAAGACGATGATGATGATGCTAGTCAAAATATTAGTGAAACAATACAAAAAAATGATTCAATGGAAGTGTTAGAACTTGATAACACTAATGCACAAAAAGAAATCGATAAAAGTCCTCTTGATACATCAAGCTCTTCATTTTTGCCAACAAAAGCACATGGATTAAATAAACCAGATGTTATGTTGGAAATCCCAACTCAAGACTTTGATGAATTCAGTGATGATGATGACGATTTCGGTCAAGAACAAATAGCCAGTCTTGTAATGTCTCCAGATGTGGAAACAGGTAAACTAGAAGAGAAAGACAAAAGCAGTAGACAGTCTGCTGAGAAGGAATCTAATAAATCTATATCTATGGAAACAGACAATAATGATGAATGCCAAAACATTTTTTCCACTTTAGAGGGTGATAATGAACAACCTGAAATATCAAATAATCAACTAGAACAACAGGACCAACCAGATACCTCCAATGTTGAAGTAAATAATGAACCTATTCCTAAAGAAAACACATTACCATCATGTGATGATCAAGTTGAAAATAATACTAAATACGAAAATGGTTCTTCTGTTATTTTAAAAGACAAAAGAGAAAAACAATCTGAAATTCAAGAAGAAACTGATGGTAACCAAGAACTATCAGAAAGTAAGTGTGATGATATGGTAGAAAAAGAACCACAGCAATCAGCAGCAACCTCAAGTGAAGACCATACATTAGACAACATGCACCAAAATCCAGATGTAGAAGAAATGTCAGATAGTCTAGGTTTGCTAGCTGAATCATCAAGAGTAATGGATGATGATGAACAAGAAGAAGAGCCTGATGATGATGGAGATGGTGATGAAGAGGATGATTCTGATATTGATGATGACAATAGCAATCAGGTGACAGCAGAAAATTCAGAAGATTCAAATGCTCAAAATGCAGATGTTGAGAGTAAAGCAAAAGACGATACACCTACTACTAGTGATAAAGAAGCTTCAGAGGATGGCATGAATTTTCCTGATACTGTACCAGATGCAGTTGATATTAACATAGATGAAATTGTTGTTGAAGAGGATAATATAGGAGATATACAAGTTGAGGAAACTGACTTAACAACAGCAGATAAATCGCAAAATGCTGAAGAAGATGCAGACAATAATGAACAAGAAACTGTAACAGAAGCAATAGAAGAAAGCGTAGATGTTCCAATGGACATTGAGACAGTAAAATTATCAGATACATCTGACACAGAAATGGACAATGATAAGGATGACACAAATATTGTAGAAATAGTTACAAATGAGACAGCCGTTGATGATAATGAAGTATATGTTATAAATGAAAATATGGGTGATGAAATAGTGAGAACAGAAATTAATAAAAATGTTGTAGATTGTGTTTATTTAGAAGCAACTTCTTCTGATGAAGAAGTATGCGAGGTGGACCAGGAATCAGAATCGACGACTGTGAAGATGCCTGCTGACATTGATGTGATCTCGTCATCAGGTGGAGCTACCAGCGAAATAGTGATGAAAGAGACTGAAACTGTTATCAGTGGACTCCCGAAACCGCCGCCGATGAAACCGGCAAGAATAAACACATCTGAGGTGTCGATAAAAACAACTCACAGCAAAAAGGAAACTATAACACCACCTGAACTGCAGGAGGAGTCTTCAGGTCAAGTAGTTAACTTGGACTCTGATGATGAAGAACAGGAGAAACTAACGATAACAGAATCTACACCTTTAGAGGAAGGGAAGACCGTTGGTGGCATAAAATGTGTGAACAGGAAGTGTCCGCATAACCCCTCAGCGCAATACTCAATAGCCGATTCCCGAGTCATAGCGTTTTTTGAAGGCGACAAAAAGAAACGCTCGTACGTTTGCGAGGACTGCTATGATATTATACACCAGAAAAATCGGGAGCTCATCACTGGTATTCAGGAGTTCAAGCCATTTATGGAGTTTGACTTTGGTAACTACCATGAGGAGCTGGTGGAAATCTCCGACTCTGAGTCCGAGGAGGAAACTGAACCTATTAAAGATGGAGGAGACTTGATAGGTGACAAAACTGCCAAGTTTTTGGAAGATAATTTGACGGACATCTTCAACGAGGTTTGGTCAAAGTACAGGATGGACGAGCGCCTGGACGATACCGCAGCAGAGATGCAAGAAGAATTGAAACGGCTACAGAAGGAAAGCCTGGAGATCGACGAGCTGTTCAAGCAGTGTCAGATAGCTAACGACAAGCTGCGGACGGAGCTGTACGCGACGTTCGAGCCCGACATACACGAGCTGCCACCCATCAACATCGATGACGTCGCCGAAAAGACTGTAATAACCGCAGAAAAAGATGTCAAACCGGCACCTGCTCAAGAGATGCCGTCTAAGCGTCCACGTCGCTCGACAGTGGGGTGGTTGGAGGGGCCGCCCTCGAAGAAAAAGGCAATACCTATGGGATACACGCCTCTTTCGACTGTCGATGCAGAGAACACGGACATCGCGGTAGTGAAGTTGTCGCTGGAGTCTGCGCCGGCGGACTTACCGCCCAGCGGGCCGCTGACGCGCGCGCCGCTCCGCCCCGGCATGGCGGTCTACGCCAAGAAGAAAGCCTCGTGGCTCCGGGCCGTTATCTCGGAGATATTGCCCACTAAAAATTCGTCGGATCAGTTCACGATGTGCCGCGTGAAGTTCGAACACAAGAACGTGGCGAACCCGCACTCCACCGTCAGCGGTCGCCACCTGGCGTACAGCACGCCCGCTGACACGAGGATGATCATCGGTACCCGCGTTATTGCCTTATTCAAGGATGCAGGAATTAAGGAATACTACTCGGCGGGCATCGTTGCTGAGGTTCCCAATCCAGTGAACAATTATAGGTACCTGATATTCTTCGACGACGGTTACGCGCAGTACGCGGCGCACCGCGAGACGCGCGTCGTCTGTCAGAGCTCGCCGCTAGTGTGGGAGGAGGTGCACGTGGACTCGCGCCAGTTCGTCAAGGACTACATTACCAGCTACCCCGAGCGGCCCATGGTGCGCCTCCACGCTGGACAGAACCTCAAGACTGAGTTTAAAGGAAAATGGCTGTCCTGTGTGGTGGAAGCTGTGGACGCATCGCTGGTGCGCGTGGCGTTCGTGGACGGGCGGCGCGAGTGGATCTACCGCGGGTCGACGCGCCTCGCCCCGCTGTTCCTCGAGCTGCAGGCGGCCGAGCGCTCGCGGCCCCGTGCGGCCCCGCGCGCCATGCCACGCCCCCTCGGTAATAAGGGCAACATGCCGTACGTCGAGTACACGAGGTCCAACGAACAGGCGAAGTCTGCGCAGAACGCAGAGGAAATACGTCGTCAGCGGTCCGTAGCTAAGAAGTCGACAACGACGAGTCAGCCGACCCCCGCGCCCGCTACCAACCTCGATGACGTCACTAGCCGTGTTGTCTTCTATACGCCGAAGAACGCTGTGAGACCGCACAAGATGGTGCCCCACAAGTGCGGACCGCAGTGCAAAAGAACTGACGTGCTTCAGCTCAAAGACTTGCGCACATACAACCCGCTCGCTAAGCCCCTGCTCAGCGGATGGGAGAGGCAGATTGTACGCTGGCGCGGTCACAAGCATGTGATGTACGTGGGCGGGTGCGGGCGGCGGCTGCGCAACATGGCGGAGCTGCACCGCTACCTGCGCGCCACACGCTCCGACATGTCCGTCGACCTGTTCGACTTCTCGCCCAATACCCACTGCCTTGCCGAGTTCGTGCTTAACCGCTGTATCGTGTCTAAGAAGGACCTGTCAAACGGCAAAGAGAACGTGCCGGTCCCGTGTGTGAACTACTACGACCACAGCCTGCCGGAGTTCTACTCGTATAACACGGAGCGCACGCCCACCGCCGGCGTGCCGCTCAACCTGGACCCCGAATTCCTGTGCGGATGCGACTGCGAGGACGATTGCCAGGACAAGTCGAAGTGTGCGTGCTGGCAGCTGACGCTAGAGGGCGCCCGTACTATCCAAATGGAGGGTGACGTCGGCTACGTGTACAAGCGCCTGCCCAAGCCCCTCCCCACTGGCATATACGAGTGTAACTCCAGATGCAAATGCAAACACACATGTCTCAATCGAGTCGCGCAGCATCCGCTCCAGCTTAAACTACAAGTATTTAAGACTCTGAACAAAGGTTGGGGTATCCGCGCACTAAACGACGTGCCCGAGGGATCTTTCCTGTGCGTGTATGCCGGCAACCTACTCACTGATGCCACCGCCACACTGGACGGTTTGAACGAGGGCGACGAATTCCTTGCGGAGTTGGACTACATAGAGGTCGTGGAACAGATGAAGGAAGGCTTCGAAGAGGATATACCCGAAGACGCTAAAGAACAAGATAAAGAGACAAGTGAGAGTAGTTCTGAAGAAGAATCATCGGAGGAGGAAAAGAAGTCGAAGGGAGAAGATGACGATGATGTGGACTTCCATCCCGGGTACATCGGACCCGGACTCACGGACTTCACTAAAAGATTACGAAAACGTGATAAGAAAAACGCACGGGACAAAATCGCTCGGGACCAAAACGCTAAACAAGAAAATAAAGAAGACGACAAAAACCAGAAGAGCAAAACAGACAAGTCCGAGAAGAACGACGACTGCATCACGATCAGTGACGACGAAAGATCTGAAATCTCGAGCTCTGGATGTCGCAATGGAGCTTCAGAATCTGCCGGAAATTCTGATAGACGTGACAACGGGACAACCCCCACCACAAGTGCACTCGTTAATGTTGAAAGTGTGGAAAATTGGGGGTGGGGCTCGCAAATAAGAGAATGGTCCTCGGAAGAAAAGAATCTTCTACAAAAGAGCTGGCGTCGGGAGCCATCTTGTTTCACTGCTGCGGCGGGGATGCGCGCCAACGAGTTTGTCTCCAAATATAAGTCTGTTCGTACGTTATACGGTGAAGATGAGGCGTGCTACATCATGGACGCTAAGGTTCAGGGCAACATCGGCAGATATCTCAACCACTCGTGCACCCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTGGCGTTCTTCGCGCTGTCGCATGTGCGCGCGGGCACCGAGCTCACGTGGAACTACAACTACGACGTCGGCTCCGTGCCCGGCAAGGTGCTCTACTGCCTGTGCGGCGCGCCCAACTGCAAGGGCCGCCTGCTATAA
Protein Sequence
MTSKSDENTTEELCDEALNVENAVATHFEDQPTPTTHLSFNSDLKSISDDIAVQSIEEHSDDNIISIQNKECDNATKGGVKSHDTADTAEKTMAILDTLINPSDSINNEISNTIEVTEGKDETATEKQVLDDKTSQQKQDDIAMQLKEEYSDNNIISIQNKECDNAAKGGVESHDTYTTEKTQSDQRQGSKSEIILDKLIIPSSDSINNKISNTIEVTEGKDQTATEKQVLDDKTSQQKQDDIAMQSKEEHSDNNIISIQNKECEYAAKGGVESHDNYTTEKTQSDQRQGSKSDIILDTLINPSSNSINNKISNTIEVTDGKDETATEKQVLDDKTSQQEQDDIAMQSNEDHSDNNIILIQNKEGDNATKSGVESHDTYTTEKAQSDQGQGSKSDIILDTLINPFSDSINNKISNTIEVTKGKDETAREKQVLDDKTSQQEHNEVYNEMDVDVLPNTKREQIIVGKANDDSVKVTDDADKNPESELKMDDYDDSDNMTKPSSYTEKDKEDILVPSKPETSSTETPGIELESSLQYDNNGDDKFKLVWEDDDDDASQNISETIQKNDSMEVLELDNTNAQKEIDKSPLDTSSSSFLPTKAHGLNKPDVMLEIPTQDFDEFSDDDDDFGQEQIASLVMSPDVETGKLEEKDKSSRQSAEKESNKSISMETDNNDECQNIFSTLEGDNEQPEISNNQLEQQDQPDTSNVEVNNEPIPKENTLPSCDDQVENNTKYENGSSVILKDKREKQSEIQEETDGNQELSESKCDDMVEKEPQQSAATSSEDHTLDNMHQNPDVEEMSDSLGLLAESSRVMDDDEQEEEPDDDGDGDEEDDSDIDDDNSNQVTAENSEDSNAQNADVESKAKDDTPTTSDKEASEDGMNFPDTVPDAVDINIDEIVVEEDNIGDIQVEETDLTTADKSQNAEEDADNNEQETVTEAIEESVDVPMDIETVKLSDTSDTEMDNDKDDTNIVEIVTNETAVDDNEVYVINENMGDEIVRTEINKNVVDCVYLEATSSDEEVCEVDQESESTTVKMPADIDVISSSGGATSEIVMKETETVISGLPKPPPMKPARINTSEVSIKTTHSKKETITPPELQEESSGQVVNLDSDDEEQEKLTITESTPLEEGKTVGGIKCVNRKCPHNPSAQYSIADSRVIAFFEGDKKKRSYVCEDCYDIIHQKNRELITGIQEFKPFMEFDFGNYHEELVEISDSESEEETEPIKDGGDLIGDKTAKFLEDNLTDIFNEVWSKYRMDERLDDTAAEMQEELKRLQKESLEIDELFKQCQIANDKLRTELYATFEPDIHELPPINIDDVAEKTVITAEKDVKPAPAQEMPSKRPRRSTVGWLEGPPSKKKAIPMGYTPLSTVDAENTDIAVVKLSLESAPADLPPSGPLTRAPLRPGMAVYAKKKASWLRAVISEILPTKNSSDQFTMCRVKFEHKNVANPHSTVSGRHLAYSTPADTRMIIGTRVIALFKDAGIKEYYSAGIVAEVPNPVNNYRYLIFFDDGYAQYAAHRETRVVCQSSPLVWEEVHVDSRQFVKDYITSYPERPMVRLHAGQNLKTEFKGKWLSCVVEAVDASLVRVAFVDGRREWIYRGSTRLAPLFLELQAAERSRPRAAPRAMPRPLGNKGNMPYVEYTRSNEQAKSAQNAEEIRRQRSVAKKSTTTSQPTPAPATNLDDVTSRVVFYTPKNAVRPHKMVPHKCGPQCKRTDVLQLKDLRTYNPLAKPLLSGWERQIVRWRGHKHVMYVGGCGRRLRNMAELHRYLRATRSDMSVDLFDFSPNTHCLAEFVLNRCIVSKKDLSNGKENVPVPCVNYYDHSLPEFYSYNTERTPTAGVPLNLDPEFLCGCDCEDDCQDKSKCACWQLTLEGARTIQMEGDVGYVYKRLPKPLPTGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTLNKGWGIRALNDVPEGSFLCVYAGNLLTDATATLDGLNEGDEFLAELDYIEVVEQMKEGFEEDIPEDAKEQDKETSESSSEEESSEEEKKSKGEDDDDVDFHPGYIGPGLTDFTKRLRKRDKKNARDKIARDQNAKQENKEDDKNQKSKTDKSEKNDDCITISDDERSEISSSGCRNGASESAGNSDRRDNGTTPTTSALVNVESVENWGWGSQIREWSSEEKNLLQKSWRREPSCFTAAAGMRANEFVSKYKSVRTLYGEDEACYIMDAKVQGNIGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALSHVRAGTELTWNYNYDVGSVPGKVLYCLCGAPNCKGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01217516;
90% Identity
-
80% Identity
-