Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.17 7.5e+03 -0.1 0.1 18 32 46 61 39 76 0.70

2 7 0.0087 3.8e+02 4.1 0.0 21 52 105 136 96 138 0.85

3 7 0.19 8.5e+03 -0.2 0.0 21 43 133 155 129 161 0.85

4 7 3.6e-05 1.6 11.7 0.1 21 45 161 185 153 193 0.88

5 7 0.069 3.1e+03 1.2 0.1 21 43 189 211 185 215 0.86

6 7 0.0012 51 6.9 0.1 14 44 209 240 200 248 0.75

7 7 1.8e-06 0.08 15.9 0.0 21 45 245 269 237 273 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.17	7.5e+03	-0.1	0.1	18	32	46	61	39	76	0.70
2	7	0.0087	3.8e+02	4.1	0.0	21	52	105	136	96	138	0.85
3	7	0.19	8.5e+03	-0.2	0.0	21	43	133	155	129	161	0.85
4	7	3.6e-05	1.6	11.7	0.1	21	45	161	185	153	193	0.88
5	7	0.069	3.1e+03	1.2	0.1	21	43	189	211	185	215	0.86
6	7	0.0012	51	6.9	0.1	14	44	209	240	200	248	0.75
7	7	1.8e-06	0.08	15.9	0.0	21	45	245	269	237	273	0.89

Coding Sequence: ATGTACCAAGACCCAGTAGCGACAACCTCCGAAAAAGGGACGAGTTATATTGACAGCAGTGGCGCCGAGAAACGATTCCAGTGTGCAGTGTGCTCGAAAGGATTCTTCTATAAAAGCGACCTTAAATCTCACATGAGAAGTCACACAGGCGAGAAACCTTTCCAGTGTACGATGTGCGAAAAAAGTTTCAATCATAACGGAAAGCTGACAATTCACATGAGAACTCATACTGGCGAGAAGCTAATGAGCACGGTTTGCCAAAAAGGATTCAATCAAACAAACGACTTGAAAGTTCACATGAGGACTCATACCGGCGAGAAACCATATCCGTGTACAACGTGCGATAAAGCGTTTAAGAAAAGTGGCGACTTGAAAATTCACATGAGGATTCATACGGGAGAGAAACCTTATAAGTGTTCGGAGTGTCAGAAAGGTTTCAACCAAAGTGGTGAGTTGACTATTCACACGAGGACTCACACGGGAGAAAAACCATATAAGTGTACATTATGCGCAAAAGTGTACAATCAAAGTGGGAAGTTGAGAAATCACATGAGAACTCACACTGGAGAACGGCCGTATAAGTGTAAAGTGTGCGGGAAAGCTTTCAATCAAAATGGCGAGTTGAAAATTCATACGAGAAGTCATACAGGCGAGAAGCCTTATAAGTGCCCGGTGTGTCAGAAAGGTTGCACACATGGGAGTGAGCTGAAAGTGCACATGAGGACTCATACGGGGGAGAAGCCTTTCCGGTGCCCGGTGTGCCCGGCAGGATTTAACCAAAGTGGCAATTTGAAGAGTCACATGAAAACGCATGCGGTAGATACTTATATACCAATTCTCAATTTTCCTAGCCAGGTTTAG
Protein Sequence: MYQDPVATTSEKGTSYIDSSGAEKRFQCAVCSKGFFYKSDLKSHMRSHTGEKPFQCTMCEKSFNHNGKLTIHMRTHTGEKLMSTVCQKGFNQTNDLKVHMRTHTGEKPYPCTTCDKAFKKSGDLKIHMRIHTGEKPYKCSECQKGFNQSGELTIHTRTHTGEKPYKCTLCAKVYNQSGKLRNHMRTHTGERPYKCKVCGKAFNQNGELKIHTRSHTGEKPYKCPVCQKGCTHGSELKVHMRTHTGEKPFRCPVCPAGFNQSGNLKSHMKTHAVDTYIPILNFPSQV

Sequence clustering based on sequence similarity using MMseqs2