Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.026 3.4e+02 2.0 0.3 27 49 11 33 8 37 0.83

2 7 0.072 9.4e+02 0.6 0.1 25 49 68 92 55 96 0.81

3 7 0.0037 49 4.7 1.1 26 48 98 120 93 123 0.81

4 7 2.6e-06 0.034 14.8 0.4 25 48 158 181 151 186 0.89

5 7 0.0002 2.6 8.8 0.9 27 50 189 212 186 215 0.86

6 7 3e-05 0.39 11.4 0.1 26 48 236 258 231 263 0.92

7 7 0.027 3.5e+02 1.9 0.1 15 32 276 293 269 305 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.026	3.4e+02	2.0	0.3	27	49	11	33	8	37	0.83
2	7	0.072	9.4e+02	0.6	0.1	25	49	68	92	55	96	0.81
3	7	0.0037	49	4.7	1.1	26	48	98	120	93	123	0.81
4	7	2.6e-06	0.034	14.8	0.4	25	48	158	181	151	186	0.89
5	7	0.0002	2.6	8.8	0.9	27	50	189	212	186	215	0.86
6	7	3e-05	0.39	11.4	0.1	26	48	236	258	231	263	0.92
7	7	0.027	3.5e+02	1.9	0.1	15	32	276	293	269	305	0.83

Coding Sequence: ATGTACCAACACCTTCTCGACACTTTCGTTTGCGGCTACTGCAGCCGCACCTTCACACGCAAGTACAACTTACGGGTGCACATCGAAAACTGCCATTTGAACAGTACGACCTGTTGCGACGTCTGCCAGCTGACCTTCAACAGCCTTTCCGGTCTGCAGATCCATAAAAACCGCGGCCACAACCGCAACGATGAGGCCTACCCGGAATGCGACCTTTGTGGCCGcatttttaaaagaaaacaaaacatcGTCTCCCACATGAACACCATCCACCTTCAGACCAAGGAGATCTGTTGCCACAAGTGCAAAAAGAGTTTCACGACCCAGCGGAACTTGAAACGACATCTGCATCAAATTCACAATCCAAACTTTGAATATTTGGAATGCAATGACTGCAACAAAGTGTTTAAAGGAAAGCATTCCCTCATCGCACACATACAGGCCGTTCATGACCCAACAGAGAAGTACACATCCAAATGCCACATTTGTGCGAAGGTGTATACCAACGCACGCAATCTTAAAAGGCACTTTGAAGCGTACCACACTGATAGGGGAGAATTCAAATGCTATCAATGCAATAAGATGTACACAACCAGTCAAAGTCTGAGAAGACACACTCGGTTGAGACATTTGTCGTCCAATAGTAAGGAGAACTCGTTTGCACAGGAGGTGCAAGAATTAGAGGAGTCATTTACGAACGACCTCATCTGTCCGGTCTGCTGCAAGAGCTTTGAAGAAGAGCAGAATCTGAGGCAACATGTGAAGTTGGAGCATTCGTTTACACGCTCGTGTCGCGTCTCCGTGCGGGCGGTACACTCCCGCGCGCCCGCCGCACACTCCCGCGAACAGAAGACCGCGCGCTGCAACGTCTGTTTCACCAAACTGCTCACCAAAGagAGCTCGGCGGTGCACCTGACCTGCTGCCCTGTGCCCCGCGGTGCGCTGCGCTGCCCGCACTGCTCGCGGCTGTTCAGCGAGCCCGCCAGTAGAGACCTCCACGCACGAGTCTTCCATCAGAGTGACGTCACTTCCGCCGAGCGTGGTGACGTCACCTCCGGGCCGGTCGCACGGCAAGCAAACACTATTTAA
Protein Sequence: MYQHLLDTFVCGYCSRTFTRKYNLRVHIENCHLNSTTCCDVCQLTFNSLSGLQIHKNRGHNRNDEAYPECDLCGRIFKRKQNIVSHMNTIHLQTKEICCHKCKKSFTTQRNLKRHLHQIHNPNFEYLECNDCNKVFKGKHSLIAHIQAVHDPTEKYTSKCHICAKVYTNARNLKRHFEAYHTDRGEFKCYQCNKMYTTSQSLRRHTRLRHLSSNSKENSFAQEVQELEESFTNDLICPVCCKSFEEEQNLRQHVKLEHSFTRSCRVSVRAVHSRAPAAHSREQKTARCNVCFTKLLTKESSAVHLTCCPVPRGALRCPHCSRLFSEPASRDLHARVFHQSDVTSAERGDVTSGPVARQANTI

Sequence clustering based on sequence similarity using MMseqs2