Aalb022912.2
Basic Information
- Insect
- Argyresthia albistria
- Gene Symbol
- egg
- Assembly
- GCA_963457715.1
- Location
- OY735281.1:2767323-2796003[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 3.4 1.3e+04 -3.6 0.1 31 38 350 357 323 358 0.80 2 3 0.42 1.6e+03 -0.7 0.0 5 18 390 403 387 415 0.78 3 3 2.6e-16 9.7e-13 48.1 0.0 5 75 425 488 421 490 0.89
Sequence Information
- Coding Sequence
- ATGATCGAGGCGCCAGCGGCGTACGCGCCGGCCGCCAAGCGACAAGCGATACCGCTCGGCTTCAAGGAGAATCAGGAGAGCAAGGATGATGATAGTATCAGCGTAGTGAAGCTGTCAGCGGAGGCTGCGCCGGCGTCGCTCCCGCCGGCCGGTATGCTCACGAAGCCGCCGCTGAAGGTCGGGGACTTATTGCTGGCGCGGCGCGAGACTTCCGGGACTTGGCTGCGGGCGACTGTGCTGGAGGTGCTGCCGAAGGGCTCATCGCAATTCACGACGTGTCGCGTACGTTTCGAGAACAAGAGCAAACTCGTGGTCACACTGACGGCGCGCCATCTTGCGTACAGCGACCCGGCCAACGTGAGGCTGGTTATTGGTACCCGCGTGATAGCCCTGTTCATAGACACGGCTAACACCCTGAAGCGTCGGATGTTCTACTCGGGAATCATCGCCGAAATGCCGAACCCCGTCAATAACTACCGCTACCTAATCTTCTTCGACATCGGCTACGCGCAATACGTGACGCATGCGGACTCGCGCGTCGTCTGCGAATGCTCGCGTCTCGTGTGGGAGGAAGTGCAGCCGCTCAGCCGGGAGTTTGTGCGGCAGTACCTGGTGAACTACCCGGAGAGGCCGATGGTCCGGCTGCATGCCGGACAGAGTTTGAAGACCGAGTGGAACGGCAAGTGGTGGGTCTCGAAGGTGATGAAGGTGGACGCGTCGCTCGTGCAGGTGCACTTCGAGGCCGACGACCGCACCGAGTGGATCTACCGCGGCTCCACGCGCCTCGCGCCGCTCTACCTGGAGCTGCAGGCGGCGGAGCGCCCGCGGCCGCGCCACAGCACTGCCAACAAGCGGAACCaaCAAAATATGCCGTACGTGGAGTACACACGGAGCGACGAAGCCGCAGACCTAGCACAGAAGACAGAGGAACAGATCAAACTACACAATGAGGAGCTACGCCGCCAACGCGCCGTGGCTAAGAAGTCGACGGCGGCGCCACTGCAGCCGCACTCCGTCAGCTATCCGCAGCCATTAGACAGTGTCATGAGCAGGGTCGTGtACTACACGCCGAAAGCAGCCGTCAAACCGTACAAGATGGTCACGCACACATGCACGGAGCGCTGTCGTCGCACCGACGTGTTGCCTCTGAAGGAACTGCGGACGTACAACCCGCTCGCCAGGCCGCTGCTGAGCGGCTGGGAGAGgatacactcgAGCACGGAGCGCTGTCGTCGCACCGACGTGTTGCCTCTGAAGGAACTGCGGACGTACAACCCGCTCGCCAGGCCGCTGCTGAGCGGCTGGGAGAGGCAGATAGTCCGCTACAAGGGCCGTAAGGAGGTGATGTACCGCGCGCCGTGCGGCAGGCGCCTGCGCACCATGCCGGAGCTGCATCGGTACCTCACCGCCACGCAGTCGGAGATGGGCGTGGACCTGTTCGACTTCAACGCCATGACGCACTGCCTGGCCGAGTTCCTGCTGAACCGCTGCCGGGTCACGAAGAAGGACCTTTCGCACGGTAAAGAGAACGTGCCCGTGCCGTGCGTGAACTACTACGACAACTCACTCCCGGAGATGTGTCTGTACAACACGGAACGCACCCCGACCGCGGGCGTGCCGCTCAACCTGGACGGCGCGTTCCTGTGCGGCTGCGACTGCGAGGACGACTGCCAGGATAAAAGCAAGTGCCAATGCTGGCAGCTGACGATAGAGGGCGCTCGTACTATCGGCATGGACGAGGACGAGGTCGGATACGAGTTCAAACGGCTTCCGGAACCGGTGCCGACTGGCATCTACGAGTGTAACTCCAGATGTAAATGCAAGCAGACCTGCCTCAACCGAGTAGCGCAGCATCCGCTACAGCTCAAGTTGCAGGTGTTCAAGACACAGAACCGCGGTTGGGGTATACGCGCCCTGAACGACGTGCCGAAGGGAGCCTTCCTCTGTGTGTATGCGGGGAACCTGCTCACAGATGCTACCGCCAACTTGGACGGCCTCAACGAAGGCGACGAATATCTGGCGGAGCTGGACTACATCGAAGTGGTCGAGCAGATGAAGGAGGGCTTCGAGGAGGACGTCCCGGCGAAGGACAAGATACTTGACAAGAAGGAGGGGAGCTCCGGCAACGAGGAGGAGGAGTCCAGCTCCTCGGAGGAGGAGGAGCGGCCGAGCAAGAACGAGGTCGCTGATGATGACTTCAAACCGGACTACATTCCGATGACGGCGCCCTTCAAGAAGAGTCTCCGCAAACGagataagaagaagaaagaagaagcaAAAGAAGAATCAGCCGAGACGAGGAAGGAGAGATCAGAAGACGACTGTATCATGATTAGTGATGACGATGAAGTGAAGGAGCCCTCGAACTTCACAGCGCAAGCGGGCATGGCTGAGGGCGACCTCTCGCCGAAGACCAAGAGTGTCCGTTCGCACTTCGGCAAAGACGAGGCTTGTTACATCATGGACGCGAAGGTGCAAGGAAACATTGGCAGATATCTCAACCACTCGTGCATGCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCTGCGGTTCCCGTGGGTGGCGTTCTTCGCGCTGTCGCACGTGCGCGCCGGCACCGAGCTCACGTGGAACTACAACTACGACGTCGGCTCCGTGCCCGGCAAAGTGCTCAAGTGCTTCTGCGGAGCGCCGAACTGCCGCGGACGACTGCTGTAG
- Protein Sequence
- MIEAPAAYAPAAKRQAIPLGFKENQESKDDDSISVVKLSAEAAPASLPPAGMLTKPPLKVGDLLLARRETSGTWLRATVLEVLPKGSSQFTTCRVRFENKSKLVVTLTARHLAYSDPANVRLVIGTRVIALFIDTANTLKRRMFYSGIIAEMPNPVNNYRYLIFFDIGYAQYVTHADSRVVCECSRLVWEEVQPLSREFVRQYLVNYPERPMVRLHAGQSLKTEWNGKWWVSKVMKVDASLVQVHFEADDRTEWIYRGSTRLAPLYLELQAAERPRPRHSTANKRNQQNMPYVEYTRSDEAADLAQKTEEQIKLHNEELRRQRAVAKKSTAAPLQPHSVSYPQPLDSVMSRVVYYTPKAAVKPYKMVTHTCTERCRRTDVLPLKELRTYNPLARPLLSGWERIHSSTERCRRTDVLPLKELRTYNPLARPLLSGWERQIVRYKGRKEVMYRAPCGRRLRTMPELHRYLTATQSEMGVDLFDFNAMTHCLAEFLLNRCRVTKKDLSHGKENVPVPCVNYYDNSLPEMCLYNTERTPTAGVPLNLDGAFLCGCDCEDDCQDKSKCQCWQLTIEGARTIGMDEDEVGYEFKRLPEPVPTGIYECNSRCKCKQTCLNRVAQHPLQLKLQVFKTQNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGFEEDVPAKDKILDKKEGSSGNEEEESSSSEEEERPSKNEVADDDFKPDYIPMTAPFKKSLRKRDKKKKEEAKEESAETRKERSEDDCIMISDDDEVKEPSNFTAQAGMAEGDLSPKTKSVRSHFGKDEACYIMDAKVQGNIGRYLNHSCMPNVFVQNVFVDTHDLRFPWVAFFALSHVRAGTELTWNYNYDVGSVPGKVLKCFCGAPNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00162835;
- 90% Identity
- -
- 80% Identity
- -