Aleu030850.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Argyra leucocephala
Gene Symbol
-
Assembly
GCA_963942445.1
Location
OZ012681.1:109427066-109430968[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.7e-14 3.7e-10 40.4 0.0 4 71 288 350 286 353 0.85
2 2 2.3 2.3e+04 -3.8 0.0 9 27 401 419 398 422 0.82

Sequence Information

Coding Sequence
ATGGAAGTAGAAGAAAATGGTTGTGATGTTTCTACAGaagatgataaaataaaattaatttttacatctgAAGAAAATACTTGTGAATCGATTGAAGAAGCTTCCGAAGAAATTGTTAGTGAAAGcccaattgaaaatgaaatttctaaaatgGAAGTTGatgatataaaagaaaataaaattttaaaagctaaaaatgATATTGAAGATGATATTAGAATGATATGTGGTAGTGAAGAATTGAATCGATCATCTCAAGATAAAGAACAATCTATTGACAATAATATTCTTGAAACTTTACAAGAACAATCATCGGATCAAccaacaaatataattgaaaaaactcAAAGAAATGAAGGTGGTCATCCTCatcctcatcatcatcatcagcaacaaacaacaataaatttaaaacgaacACTTTCTCAAAATTCTACAGGAACTATTAAAGATGGTGATAGTGATCAAGATCTATTTGGTTTTTATGatggaaaatttgtatttggtaaaaaaattaaaattaattcaaatgaaattgatAGTGAAATCATAGgttctaaatttaaaagaattttaaatgattcaGAAATATTAGAAGATgtggaagaagaagaagaaattaataatacaattgaaaaaattaaacaacaaaatggTAAAATAGATAATTCGGATAAAGTTAGTTCgcaacaaaatataattgaacaaaatttgaatatatcaaaagtaaataatgaaaatgatgataataaaattttatcaactcCAGTTGTTTctccatcatcatcatcatcaattcaaatatcatattcatcgtcaacaacaacaacagcaacaacaccAAAATTACGTCCCTCAGAAGATCCAGTATATCGAAAACCATTTGAAATGGGTTGGAAACGTGAAATTGTACTAAGAGCACTTCCAGGCTCAAAAGATAAAGGTgaagtatattatattactcCAACTGGCAAAAAATTACGTACACGTCATgaaatacaagtgaatttaaCACCTGGGCTTgcattagaaaattttacatttagtaAAGATCCTCTTGGTGCTGATCCAGAAGATGAAATTATTAGAAGTGCAAAACCAACTGGTCGCAGTACTGAAATATCAACACCAAGAACACCTGAAATGAATACACCAACTTCTGGTAAACGTATTCCAAAACCTAAAGGTCCAAAAGGAGCTAGCCCACCACCTCAAGGTTGGACATCAACACAAGCTGTCAAAACACAAGGTTCCCGTTCTCATTCTAGATATTCAACAAATGCAGATgatcatttttcaaaatcatctGGTAGAGGTTTGAGTAGTACTAGTAGTGACAACAATAGTTCTAATAATAAATCTAGtaacattaataaaaaGGGTGAACCTTGTACAATTCAATGTGTCCTTGCAATGGGATTAATTCCACAATTacaatgtataaaatgtttgtgtcTATATCATCATGAATGCGTTGGTTTGGATCGTAATATTGATGACTTTCAATCGGAGATCAAATCAACTTCCTTATCATCTATTAATATTTCACCAAAACATGTCCAATCGATTGCAGTCCTCAATGGACGcaaatatttagttatacatAAACCAGGAATTCCTTCAAATGAacatTCTGAGCAATTTACAATGACATCTAATAAATCTTCACCAGTGAAAGTTCAGTATGTTGATTCATATGTTCATAATCTTTTTGGTAATGTTTCTGCCGcatatgatataattttaaatgtttttaaataccTTAAAGTACAGgaaTTATTACGTGCAGCTTGTGTTTCACGTCTATGGAATCATTTAGCTAATGAACGTTCGTTATGGAAAGTGGTTAGAATGAAAAATTCACAGGTAAATGATTGGGCTGGTTTTGCAGCAACATTAAGTCGAAATTCAACACAGCATTTGGATTTGAGAAAAATGATTTGTCCGAAGAGTGGTGTTGATCGTATGTGgacaaattttaatgataacaTTCAAAAAGTTTTTACATTGAAAACAATTGATTTGGGCAGATGTCCAGCcagtgttgtacaaaatttatttttagcaacacctcaattaaacattttaaatgcaACATCAATTAAGagtgaaacaattaatttggaaaatttaaataaattatcaaatttgacTGAATTACGTTTAAAATCGGTTGAACGTTGTAATCTAGTTGGTGATTTATCATCATTTGCATtccttaaaaatttacaacatttaAGTTTAACATCAATAAATGATTTGGgtacaaaaaatatagaaattttaggTCAACTAACTGAATTAGAATCATTAGAAATTGGTGAATGTTcaacaattcaacaaaattttggaattgaagtattagcaaatttaaaaaagttacaaCGATTGCGCTTAGAAGAGAGTACAGAGATCTCAGTTACTTTTTCAATATTAGATCAAATTgctgaaatggaaaatttacaacaattagAATtggttaattttgatattagagATGGATTTGAACAGAAAATAATatcatgtaaaaatttgaaacgTTTTCTTTTAATACCAACTTATGTTGCACAATCAGcaacaacaaatcaaattattttaagttcgATGCGTAAATTGAAAACACTAGAATCATTTACATGGGTTGTTACATTAGAATTGTTATCTGTAACAGCATTATATGTTGATCAGTGTGGTTCAAGAGATCGTCGTAATTTTAATGATTGTATTCCAGTTTTAAAACCTGTGCCAGGTGCATCTCATAAAGAAAAAGATGAAGCTCCAAATAAAACAACTAATGCTGATAtacaacaaattgaaatattaccGTTATCaacaattaaagaaattttggaTGATGGTACCCCAAATACAAATCATAAAATTGTACGTGTGGCATTTAATACCACTTGGAGACAAAcatttgttgaataa
Protein Sequence
MEVEENGCDVSTEDDKIKLIFTSEENTCESIEEASEEIVSESPIENEISKMEVDDIKENKILKAKNDIEDDIRMICGSEELNRSSQDKEQSIDNNILETLQEQSSDQPTNIIEKTQRNEGGHPHPHHHHQQQTTINLKRTLSQNSTGTIKDGDSDQDLFGFYDGKFVFGKKIKINSNEIDSEIIGSKFKRILNDSEILEDVEEEEEINNTIEKIKQQNGKIDNSDKVSSQQNIIEQNLNISKVNNENDDNKILSTPVVSPSSSSSIQISYSSSTTTTATTPKLRPSEDPVYRKPFEMGWKREIVLRALPGSKDKGEVYYITPTGKKLRTRHEIQVNLTPGLALENFTFSKDPLGADPEDEIIRSAKPTGRSTEISTPRTPEMNTPTSGKRIPKPKGPKGASPPPQGWTSTQAVKTQGSRSHSRYSTNADDHFSKSSGRGLSSTSSDNNSSNNKSSNINKKGEPCTIQCVLAMGLIPQLQCIKCLCLYHHECVGLDRNIDDFQSEIKSTSLSSINISPKHVQSIAVLNGRKYLVIHKPGIPSNEHSEQFTMTSNKSSPVKVQYVDSYVHNLFGNVSAAYDIILNVFKYLKVQELLRAACVSRLWNHLANERSLWKVVRMKNSQVNDWAGFAATLSRNSTQHLDLRKMICPKSGVDRMWTNFNDNIQKVFTLKTIDLGRCPASVVQNLFLATPQLNILNATSIKSETINLENLNKLSNLTELRLKSVERCNLVGDLSSFAFLKNLQHLSLTSINDLGTKNIEILGQLTELESLEIGECSTIQQNFGIEVLANLKKLQRLRLEESTEISVTFSILDQIAEMENLQQLELVNFDIRDGFEQKIISCKNLKRFLLIPTYVAQSATTNQIILSSMRKLKTLESFTWVVTLELLSVTALYVDQCGSRDRRNFNDCIPVLKPVPGASHKEKDEAPNKTTNADIQQIEILPLSTIKEILDDGTPNTNHKIVRVAFNTTWRQTFVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-