Abis015886.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Argynnis bischoffii
Gene Symbol
KLHL25
Assembly
GCA_033884665.1
Location
CM066625.1:5035803-5038279[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.9e-15 1.2e-12 48.6 0.2 12 106 3 98 1 115 0.92

Sequence Information

Coding Sequence
ATGGGGGATATATCATTGAAAATTTGTGATAAAATTTTTCAAGTtaagaaagaaattttatgtGAATATAGTGATTATTTTCGAGCAATGTTCAGCGGTAATTACGTGGAAGATCAACAAAACCAAATATCTATTGATATGCTAGATCCCAACACAATGAGTATTGTTCTACAATATATGGATATAGGCTTAATTGACCTATCTGAGTATCCTCTGGCAACTATTGGCGATATAGCAGTAGCAGCAAATTTTcttcaaataattgaattaatcaaACAGATTGAATATACATTAGAAATACAAATGAGTGAGTCTAATTGGATGGAGACAATGGCTATAGCAGAAACCTCTTCTTATTCTAAACTTGAGCAACTGTCTGCTGCATTTGGactatattcatttaaaactatGAAACCTGAATATATTCCAACAATTCATAAATTGGCATGGTATTTATCACATCCATATTTAGACACTCAAAGTGAAGTGGATGTTTTCAATTTTGGTCTTCAATGGATTTTACACAATGAAACTGGTGCTGATGCACTATTAATTATTCTTGGATGCTTAGACTTCAAAAGGATATCAAATCATGATatagaagaaattaaaaaatgtactagTGAATATGAAAACAGTTTAGCCCTTAAAGTAGCAGAATGTCTTTATGAATTATCAAATAACAACTTAGAGATATGTGAAGCagttttaaatgataaaaaatctgaattatGTGAAAAGTTTACTGAGCGAGTTTGGatagaaacaataaatataataaaagaaagtaaaagcCGTCTTTTGAGTTACACTCCAGTAGTGCCAATGTGGGTCATAAAGGATTCTAAACCAGAACTGTTACCACAttatatgtacacatataataatgaaaaaggaTTTGAGCAATGGTTGGAAGTATCTGAAAAAAACTTATGGGGTTGGAGTGTTATTTCTTGGGGATTGACAAAATTAGTAATTGTATGTGGTGAACATGGGAGAGGCACGGGTATATTTATGAAGGATGTAAAAGTATATGATACATTGAAGCAAGAATGGTCAAGGCATGGTGTAGATTTACCCCCAAGAAGACATGCTGGCTTAGCTGTTGTTGGTGACTCACTCTATATTGTTGGAGGAGTAGGTGGGTTTAGGGTAGTGCTAGAAACAGCCATAATTTATGACTTAAAGCAAAGAGCTTATAGAAAAATAGCTAAATTGCCTGATGCTATTCAGAATCCAGCAGTTTGCTCACATAAGAACATGGTATATGCTGCtgggcaaaaaaatatattccgtTATGAAGACTCAGATAACTCAGATTGTTGGAGAAATATTGTGGGAACTGAGATAAGGATGAGTTGTATAAGATcatataaagattatatttattgtatacagGGTTATTTCAGTCATCTGTACAGATTTAGACCAGATATAGATCAAAGGTTggaattaataacatatttttcaaGCCTTCCAGCTACTTTGTGTAATATTGGCAATGATCTCATAGTTTTCACAAGAACAGTATGCGGAGAGTCAGATATACTGGCAGTAGAACAATTTAGTGATGATAATAAAGTAAAGAAACCTGTGGTTCTTTTTAAGCAAACAAACACGTCATTAAGAGTGAATGACGTGGCCGGCTCCTGCGTTTTGGCTATGACATTACCTCCTTTGTGTATGGAACTGTCTCAGTATCACCAGAAATATTTAACAagatatacaaatacaaattaa
Protein Sequence
MGDISLKICDKIFQVKKEILCEYSDYFRAMFSGNYVEDQQNQISIDMLDPNTMSIVLQYMDIGLIDLSEYPLATIGDIAVAANFLQIIELIKQIEYTLEIQMSESNWMETMAIAETSSYSKLEQLSAAFGLYSFKTMKPEYIPTIHKLAWYLSHPYLDTQSEVDVFNFGLQWILHNETGADALLIILGCLDFKRISNHDIEEIKKCTSEYENSLALKVAECLYELSNNNLEICEAVLNDKKSELCEKFTERVWIETINIIKESKSRLLSYTPVVPMWVIKDSKPELLPHYMYTYNNEKGFEQWLEVSEKNLWGWSVISWGLTKLVIVCGEHGRGTGIFMKDVKVYDTLKQEWSRHGVDLPPRRHAGLAVVGDSLYIVGGVGGFRVVLETAIIYDLKQRAYRKIAKLPDAIQNPAVCSHKNMVYAAGQKNIFRYEDSDNSDCWRNIVGTEIRMSCIRSYKDYIYCIQGYFSHLYRFRPDIDQRLELITYFSSLPATLCNIGNDLIVFTRTVCGESDILAVEQFSDDNKVKKPVVLFKQTNTSLRVNDVAGSCVLAMTLPPLCMELSQYHQKYLTRYTNTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00160002; iTF_00248261; iTF_00247361; iTF_00723297; iTF_00776827; iTF_00777475; iTF_01182022; iTF_00775401; iTF_00781163; iTF_00776147; iTF_00779635; iTF_00781974; iTF_00457370; iTF_00621370; iTF_00778140; iTF_00778876; iTF_00782781; iTF_00213695; iTF_00212704;
90% Identity
iTF_00160002;
80% Identity
-