Apag003850.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Arge pagana
Gene Symbol
LZTR1
Assembly
GCA_963969455.1
Location
OZ018309.1:4610442-4614037[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2e-14 5e-12 45.9 0.7 2 108 351 486 350 488 0.85
2 4 0.46 1.1e+02 3.0 0.1 76 108 486 518 481 520 0.85
3 4 2.7e-18 6.6e-16 58.4 0.0 8 96 578 666 572 681 0.86
4 4 1.9 4.6e+02 1.0 0.0 76 100 680 704 675 713 0.79

Sequence Information

Coding Sequence
ATGGACAGCATTGCGACCGCTGAGTGTCTTACGTTAGATTTTGGACCGTTTGAAACAGTACACCGATGGCAACAAATGCCAGAATGCGATGAATTCGTTGGCGCCAGGAGAAGCAAACATACGGTAGTAGCTTATAAAGATGCTATTTACGTTTTTGGAGGAGACAATGGAAAGAGCATGTTGAATGACTTACTTCGATTTGATGTCAAAGAAAAATCATGGGGGCGTGCATTTGCCACTGGAATCCCACCTGCACCTCGATATCATCATTCAGCTGTAGTTCACGATGTATCAATGTTTGTATTCGGCGGATACACTGGAGATATTCACTCAAATTCAAACTTGACAAATAAGAATGATCTATTTGAGTACAAATTCAAAACTGGCCAGTGGAcagaatggaaatttattggaAAAACACCAGTACCAAGATCAGCGCATGGTGCTGCTGTATATGATAACAAACTCTGGATATTTGCTGGTTACGATGGAAATGCGAGATTGAATGATATGTGGACTATATCTTTATTGCCTGGGGATCCTCGTGTTTGGGAGGAAGTGGTTCAATCCGGGGATTGCCCACCAACCTGCTGCAATTTTCCTGTCGCGGTCGCTCGAGAATCTATGTTCGTTTTCAGTGGTCAGAGCGGGGCAAAAATCACAAACAGTTTGTTCCAGTTTCATTTCAAAGATAAACGTTGGACTCGAATTTCAACCGAACACATTCTACGAGGTGCTCCACCTCCTCCAGCTCGTCGATACGGGCACACGATGGTCAGTTTTGACAGACACCTTTACGTATTTGGTGGTACGGCAGATTCCACACTTCCGAATGATTTACACTGCTATGATCTTGATACCCAAACGTGGAGTGTGATTATGTCATCGGCGGACAGTCAAATACCATCTGGTCGATTGTTTCATGCAGCAGCTGTAATTGGAGAAGCTATGTTCATATTTGGTGGTACTGTGGACAACAATGTTAGGTCCGGAGAAATGTATAGATTTCAATTCTCATCTTACCCTAAGTGTACTTTGCACGACGATTTTGGTCGATTATTAAGCAGCGAGCAATTTTGCGACGTTCAGTTTATCGTTGGCGAAAGCGAGGAAAAGATAGCAGCACATATTGCTATGGTTGCTGCGAGATCTCAATGGTTAAGAGCAAGGATTAAACAAGCTCAAGACCAGCGAGAAAAGTATTTGGAGAAAATGTTTGGTACAACAGATGTACCACTGAAAGATATGCCTATGTTGGAAGTGAAATTAAAGGATGCCGTTCCCGAGGCATTTGAAATGGTGTtgaattatatatatacagatcGAATAGATCCAACGAAGAAAATAGAAGACCCAATGAGTAATAGAATCGTTTTGTTAATGATGGACGTTTACAGATTGGCTGTTCAGTTTCATATGAAAAGATTAGAACAACTTTGCGTTCATTATCTCGAAGCAACGATAAGTCACGCAAATGTTCTGGAGGCATTGCATAATGCTGCTCTGTTAAAGTTGTATTCCATAAAAGATTTTTGTCTTAGTTTTGTTGTGAAGGATAGCAATTACAATCAAATCGTGATGAGTCAAGAATTCGAAACGTTAGATCAGCCCTTAATGGTTGACATAATCAGACGACGGCAAATGCCACAATcaagaaattttttgaaatcataCGAATCAACAGGAACAACTTTAGAACAGGACATGGAGGTGTTTTTGAAGAATGTTTGTAGAGAATTCTGTGACATTACTTTGATGCTACATGGAATACCGATACCAGCACACAAAGCTATTTTAGCTGCAAGATGTAGTTATTTTGAAGGAATGTTCAGATCGTTTATGCCCGAAGATAACATCGTTAATATTCAAATAGGAGAGATGATACCTTCAAAAGAATCGTTCGACTCGTTGTTGAGGTACATTTACTATGCTGACGTCTCTATGCCTCCTGAAGACTCTCTGTACTTGTTTACTGCACCAGTTTTTTATGGTTTTACCAATAATCGTTTACAAGCTTTTTGCAAACAAAATCTGGAAATGAACGTTACTTTCGAAAATGTAATACAAATACTTGAGGCAGCGGACAGAATGCAAGCAATAGATATGAAGAAATATGCACTCAATCTCATAGTACATCACTTTAGTAAGGTTGCACGATTGccaaaattgaaacaattgaGCCGCGAGCTTTTGCTTGATATTTTGGAGGCATTGGCTGATGAAAAGAGCGAAGCACGAATGTGTCAAGACATGTCCAGCGCTAGTTTATCCAGTGACTGCTGA
Protein Sequence
MDSIATAECLTLDFGPFETVHRWQQMPECDEFVGARRSKHTVVAYKDAIYVFGGDNGKSMLNDLLRFDVKEKSWGRAFATGIPPAPRYHHSAVVHDVSMFVFGGYTGDIHSNSNLTNKNDLFEYKFKTGQWTEWKFIGKTPVPRSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLLPGDPRVWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFKDKRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFGGTADSTLPNDLHCYDLDTQTWSVIMSSADSQIPSGRLFHAAAVIGEAMFIFGGTVDNNVRSGEMYRFQFSSYPKCTLHDDFGRLLSSEQFCDVQFIVGESEEKIAAHIAMVAARSQWLRARIKQAQDQREKYLEKMFGTTDVPLKDMPMLEVKLKDAVPEAFEMVLNYIYTDRIDPTKKIEDPMSNRIVLLMMDVYRLAVQFHMKRLEQLCVHYLEATISHANVLEALHNAALLKLYSIKDFCLSFVVKDSNYNQIVMSQEFETLDQPLMVDIIRRRQMPQSRNFLKSYESTGTTLEQDMEVFLKNVCREFCDITLMLHGIPIPAHKAILAARCSYFEGMFRSFMPEDNIVNIQIGEMIPSKESFDSLLRYIYYADVSMPPEDSLYLFTAPVFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAIDMKKYALNLIVHHFSKVARLPKLKQLSRELLLDILEALADEKSEARMCQDMSSASLSSDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00087267;
90% Identity
iTF_00175823; iTF_01414306; iTF_01200292; iTF_00719528; iTF_01411624; iTF_00175149; iTF_00060432; iTF_01413456; iTF_01048306; iTF_01412434; iTF_00718711; iTF_00939703; iTF_01303545; iTF_00938845; iTF_01049021; iTF_00174399;
80% Identity
-