Apag005446.1
Basic Information
- Insect
- Arge pagana
- Gene Symbol
- -
- Assembly
- GCA_963969455.1
- Location
- OZ018309.1:24476971-24484461[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.22 6.5e+02 0.0 0.0 37 66 133 162 132 164 0.92 2 2 1.4e-15 4.2e-12 45.5 0.3 9 70 270 329 264 333 0.86
Sequence Information
- Coding Sequence
- ATGGATGTGGCGGAGGTAAATGGCGGGAACGCTGAGGCATTGCCTAACCTCGAAAAAGTGGAAACCGCAAAGACGACCGACGAACTTGAATCCGACgaaaaattagttttaagGAAAGAAAGTGATACGGAATTGAATGGAGACTTGAAAACTCCTATAAAAAAAGGATTGccgggaaaaagaaaaatgcgtAAATCGAAAGCAAATTCCACGAGTACAATTGAGAGTGGTTCCAAGCCAAAGACGAGAGGACGTAAGAGAAAATTATCAGAGAGAGAGGATATCACTTCGGAAGAGTCAACCGAGTTCAACGGATTCGATTCCCAAGGATCCGAGAACACCGAACCTGGCAGTCACGTCCTCAAGAAACTCATTGCTGAAGTAGAATCCGCAGAATCACCAAAAGGTTCGAAACGTTCCATAGCAagaaatgtttcgaaaatgcTAGATAGAAATATGGATGCAAAATCTTTACAACTGAAAGATGACGATGCTGATTCGGATGATAACAAAATGCATATTGATGAAGATATGGACCATAGTGtcgttcaaaaaataaaaaaggagaGGGACTTGGAAGAAAAGTCAGAAACTGATTCTATCGGTGCTACCAACAGTATAGAATCTGAAACTGAACCCCAAGTAAAAACGGAAGAATCTTCTATGAAATCTGCGAATTCATCTGCGAATAGTAGTCCGTCAGCTGTATCGCAAAGATCAAAAGTTAGCAGGGTTTCTCGTGGAGCTAGTCCAGGAAGCgctataaaacaaaaaatttctgtCGATATAACCAATCCTGCATATAAAGAACCTTTCAAATATGGATGGAAACGAGAAATGGTTTACAGAGCTGGTTCAGAAAATAGTGCCAGAAAAATGGcagatatttattattataccccaaaaggaaaaaaagttagaagTTTCCGCGAAGTTGTTGAATTTCTCAATAACAAGGAGCTCACAATTgataatttcacatttttcaaagaacCATTGGGTATCGATGATCCAGAAAAGGAAATAATTAGAGATGCGAAACGAATTAGAgatTCTGCCCCTGCGACACCATCACCAGCTAGAAAGGGTCCAGGTAAAAAAGCAATGCCAGTTAAAAAGGTGGTCGAAGAACCTCCGCCAAAAGCGGTTGGGAAATCTCCAAAAGCTGCAGCAAGTGCATTTAAAGTGAAATTGCCTGCTAAGAAGGGAACACCCAAAGCGGCTGCAGCAGAACCTAAACCTCCTGTAGAGGAAAGTGAAATGCTACCGCCACAAAGAAGTTCACCAGCTGCCAGGCGCAGTCAGTCGACCGTTGAAAAACCCCCACCTGCTAAAACCAAGAGAGCCTTAAAAGCTAAACTCCAGGAACCATGCAGTATACGATGTTCGACGAGTATGGGACTGATCCCAAGTCTTCAGTGTTGCGTCTGCCTTTGTCTGTATCATCCGGAATGCGTTAATAGAGCTGAATTTACTAGCAGTGACAATTACGTATGCAAGAACTGTCAACAGGACTGCGAAGATTCTTACCAGCAGCAGCAAATCACTCAATCATTAACACCACCTCCATTGATTCCGATAAGCATGTTAGGTGCTCAAAATGCAAAATCAAAACATCAACTAAATTCAACCCCCCCAAAATTACAAAGAATTCCGAAATCTGATAATTCGGAAGCACAGTTGCGAACATCGCCAAAATCTTCAAGGTCTATCCCTATTACAAAATTACCCGTTGAAAAGAATGAAGGAAGCTGGTATACGCACGCGAAAAACGAGCTATTGCATAGTTGTGACGGCACTTTACCAAAACCAGCTCAGAACATTGCTTTGATGgccggaaaaaaatatatagttGTACCAAAAAATAACGCCATGGCAGTTCAACCGGCTGTAACAGTTAAACCGGACAAAATAGGTGATAAGCCACCTACGCTTGGAGAAATATTGccttccgaaatttcaaatatgcCAGAAAATTCATTATCCTATCTTATGCATTCAAAAGCTTTGCCAATAAATGCTGTTCGAATGGATGTGGATAAATGTGACAACAACGGTGTTACCTATCCTGGTGCAACCGTATCCGATGATACAAATATCGTTCCAAACGAAACTATTACCGAGGTGAACATGATGAATACCGATGATCTCGAAGCACAATTGAAGAATATAAGTGATATCTCTGCAGATACTTCAAATGCATTGAATTCCATTGAATCAAGCGATACGAACAAAGCATATCTAACAACAGAGTCGTCGTCAGAAGTGGTAACAGATGAGAGAGATTCCAAAATTGTGCCCCCATTGAAGGTTTCTAATCCacaaaatttgggaaaatcgaTTGCGGACGAGCAGGGTGTAAACCGCGCATCAAATCAAACCAACTCTAAGAATCAAGAAATGTTAAAAACCTATGACAAAAAAAGACAGCTTCAAGTCGAGAGTGAACAGAGACAACATTTCATGGTATCAGTTTGTGCTGGATATCATGCCTTGTCACGTGTATTCCAGTATCTGAAAGTTCAAGAGCTTCTCAGAGCTGCGCGTGTATGTAAAATGTGGCGAGATTTAGCAGCACATCCCGCATTATGGAAGACAGTTCGTATGAAAAATAGTCAAGTCACCGATTGGGATGGATTAGCAGAATCCCTCAAACGACACGGTACTCAACATTTGGATCTGAGGAAAATGCTTGTGGCTGGGGAGTCGGACGATATTTGGAGGAAATTTATCACCGTCATCCCACGCGTGACCAGTCTGGTTAGACTAGAATTATGCAGGTGTCCTGTGTCGGTTGTCGAAGAAGTAATGAAGAGTTGTCCCCAGTTGGAAGTACTAAGTGCAATGACGATAAAGTGTGATTCGCTTAACTTGGAATCTGCTGGAAACCTGCGACATTGTCAAGAGTTAAAACTGAAAGCAATTAGTGGTATGTCTTTGCAGGGCGATCTTACACCGTTGAAAGACTTAACACAGCTCATGCATCTGAGTTTAACGTCCGTTAAAGAGcttgggaaaaagaaaatagatgTCCTAGAGTCATTGGCAAATCTGGAGAGCTTAGAGCTCGGCGAGTGTTCAGATTTCCCTGACAAGTTTGGTACTGTAGTTTTGCAGAAATTGCAAAAACTGGAACGTCTTAGATTAGAAAAAGGACAGGGATCCTGCTGCACCTTCGATATTCTCGAGGGTGTGTCTAAATTGGAGAAGTTGAGTCAACTCGAATTGGTCAACTTTGATGTGAAAAACGGATTTGACAAATATTTAGCTAATTGCAAGAATATCAAGAGACTACTCATAATTCCAACGTACATATCTCAGTCTGCGACTTCGAACAATATGGTACTTGGTGGTGTCACTGAGTTGTCAAATAATTTGACGCACTTTGTGTGGGGTGTGACACTCGAATTGTTACGAGTAACGGAATTATTCGTGGATCAATGCAACCAAATGAGTAAGCAAGTAACAGGCGATTCCATACCGGTACTGAAGCCAGTGCCCTGCTTGAAGCTGATCGAAGATATCGACGAGGACAGTAATGATGTTCAGAAGGgTGATGATAAGCAGCAGCCAAATCTAACGAATCCACAGGTGGATATTTTACCCCTTCCACAATTACAAAAGCTGCTTCTGACTGCATTACCAAAAACACGTGtcaagattttgaaaatacctTTCCATGCCACTTGGCGGCAAAGTATTTCCGACACGGCAACCCAGTAA
- Protein Sequence
- MDVAEVNGGNAEALPNLEKVETAKTTDELESDEKLVLRKESDTELNGDLKTPIKKGLPGKRKMRKSKANSTSTIESGSKPKTRGRKRKLSEREDITSEESTEFNGFDSQGSENTEPGSHVLKKLIAEVESAESPKGSKRSIARNVSKMLDRNMDAKSLQLKDDDADSDDNKMHIDEDMDHSVVQKIKKERDLEEKSETDSIGATNSIESETEPQVKTEESSMKSANSSANSSPSAVSQRSKVSRVSRGASPGSAIKQKISVDITNPAYKEPFKYGWKREMVYRAGSENSARKMADIYYYTPKGKKVRSFREVVEFLNNKELTIDNFTFFKEPLGIDDPEKEIIRDAKRIRDSAPATPSPARKGPGKKAMPVKKVVEEPPPKAVGKSPKAAASAFKVKLPAKKGTPKAAAAEPKPPVEESEMLPPQRSSPAARRSQSTVEKPPPAKTKRALKAKLQEPCSIRCSTSMGLIPSLQCCVCLCLYHPECVNRAEFTSSDNYVCKNCQQDCEDSYQQQQITQSLTPPPLIPISMLGAQNAKSKHQLNSTPPKLQRIPKSDNSEAQLRTSPKSSRSIPITKLPVEKNEGSWYTHAKNELLHSCDGTLPKPAQNIALMAGKKYIVVPKNNAMAVQPAVTVKPDKIGDKPPTLGEILPSEISNMPENSLSYLMHSKALPINAVRMDVDKCDNNGVTYPGATVSDDTNIVPNETITEVNMMNTDDLEAQLKNISDISADTSNALNSIESSDTNKAYLTTESSSEVVTDERDSKIVPPLKVSNPQNLGKSIADEQGVNRASNQTNSKNQEMLKTYDKKRQLQVESEQRQHFMVSVCAGYHALSRVFQYLKVQELLRAARVCKMWRDLAAHPALWKTVRMKNSQVTDWDGLAESLKRHGTQHLDLRKMLVAGESDDIWRKFITVIPRVTSLVRLELCRCPVSVVEEVMKSCPQLEVLSAMTIKCDSLNLESAGNLRHCQELKLKAISGMSLQGDLTPLKDLTQLMHLSLTSVKELGKKKIDVLESLANLESLELGECSDFPDKFGTVVLQKLQKLERLRLEKGQGSCCTFDILEGVSKLEKLSQLELVNFDVKNGFDKYLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSNNLTHFVWGVTLELLRVTELFVDQCNQMSKQVTGDSIPVLKPVPCLKLIEDIDEDSNDVQKGDDKQQPNLTNPQVDILPLPQLQKLLLTALPKTRVKILKIPFHATWRQSISDTATQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -