Alei017304.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aquatica leii
Gene Symbol
Lztr1
Assembly
GCA_035610365.1
Location
CM069432.1:165843489-165849784[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 5.4e-09 8.8e-06 28.5 0.7 4 106 360 494 357 498 0.84
2 4 0.047 76 6.2 0.1 72 108 493 528 489 530 0.84
3 4 5.7e-18 9.3e-15 57.4 0.0 7 95 588 676 582 692 0.84
4 4 0.6 9.7e+02 2.7 0.1 76 102 691 717 686 724 0.80

Sequence Information

Coding Sequence
ATGAGTTCTATTACAAACTCAGAAGCGTCTACTTCAATGTTTGATAATGGTTTAACTTTGGAATTTGGTCCGTTGGAAACCGTGCATAGATGGAATCGAATGCCTGAATGTGACGAATTTGTGGGTGCACGTCGTAGCAAACATACTGTCGTTGCTTATAAAGAAGCAATATATGTCTTTGGAGGCGATAATGGAAAGTGCATGCTAAATGATCTTTTACGATTTGATGTAAAAGAAACTTCATGGGGTAGAGCTTTTGCTACAGGTTGTCCTCCTGCACCACGATATCATCACTCTGCTGTTGTTCATAACACATCTATGTTTGTTTTTGGTGGATACACTGGAGATATTcattctaattctaatttaaccaataaaaatgatttgtttgaGTATAAGTTTTACACAGGACAGTGGGTAGAGTGGAGATTTGTTGGTAAAACTCCAGTTCCAAGATCGGCACATGGAGCTGCTGTTTATGATGGAAAGCTGTGGATTTTTGCTGGATATGATGGTAATGCTCGGTTAAATGATATGTGGACGATATCTTTAAatGACGATAGTCACACATGGGAAGAAGTTGAACAAAAGGGCGAGTGTCCTCCAACTTGTTGTAACTTCCCAGTCGCAGTTGCGCGTGAATGTATGTTTGTGTTTAGTGGACAAAGTGGTGCTAAAATTACCAACTCACTtttccaatttaattttaaaactaaaacgtGGACGCGCATTTCAACCGAGCATATATTACGAGGTGCTCCACCACCACCAGCACGCAGATATGGTCATACTATGGTTGCATTTGACAGACATTTGTACGTATTTGGAGGAGCAGCTGATAGTACTTTATCTAACGatttacattgttttgatcTTGATTCGCAAACTTGGTCAGTCATACATCCTGCTCGAGATTCGGTGGTTCCTTCGGGACGGCTTTTTCATGCAGCTGCTGTCGTAGGCGACGCAATGTTCATTTTTGGTGGAACTGTAGATAATAATGTGAGAAGCGGAGAAATGTACAGGTTCCAATTTTCTAATTATCCCAAGTGCACTTTGCACGATGATTATGGAAAAATTCTTGAATCCAAAGAAGTTTGTGACGTACAGTTTATAGTTGGAGCAGAAGAAATCAAAATACTGGCCCATCTAGCTTTAGTTGCAGCTAGATCactttatttaagaaataaaattaggCAAGCTAAGGAAGCTAGAGATAGACACCTGGAGATGTTTTTTGGCACTATAAAAGTATCTTTTAGCGACATTCCACTTTTAGAGGTAAAACTAAGAGATGCCAATTCAGAAGCGTTTGAaatggttttaaattatatttatatggaTTGCATAGATCCAACTAAAAAGGCTAAGCAAGGGGAAGATCCTTTTAGTAATCGTATTGTTTTGCTAATGATGGACGTCTACCGATTGGCTGTGCAGTTTGATATGGCCagattagaacatttatgtgtGCAATATTTAGGcgcaacaatttgtttaaaaaacgttttagaagCGTTGCACAATGCAGATAAACTACATCTAGACTTTATAAAAGAGTTTTGTTTGCGGTTTATTGTTAAAGATCCTAATTATAATTCGATTGTTATGAGCAAAGAATTTGAAGATTTAGATAGGGGTTTGATGGTTGAAATAATTCGGAGGAAGCAAGTACCGCAGCCCAAAGTTCATATAGAAAGCACGTTTGATACAGCAGGATCTTCTTTGGAACAAGATATGGCTATGTTTCTCCAAACTACTGGCAAAGAATTCTGTGATATTGATTTGGTTTTGGATGAGGTTGTTATTCCCGCACATAAAACTATATTAGCTGCTAGGTGTACATATTTTGAAGGTATGTTTAGATCATTTATGCCATCAGATAATCGAGTACGGatTCAGATTGGTGAAATGACACCATCTCGAGAATCTTTTGATTCACTTTTACGTTATATATACTATGGTGATATTAATATGCCACCTGAAGATTCTCTATATCTATTTTCTGCACCTTTCTTTTATGGATTTAGTAATAATAGATTGCAAGCGTTTTGTAAgcaaaatttagaaatgaaTGTTACGTTCGAGAATGTTATTCAAATTTTGGAAGCTGCAGATCGAATGCAAGCTACCGATATGAAAAAATTTGCTTTAGATCTCATTGTGCATCACTTTACAAAAGTGGCAAAACTAccaaaactgaaaatgttaagtaaggaattaattttagatatactgactgcttTGGCTAATGACATGAGTGACCCAAAAATGTGCCAAGACGTTTCTTCTATAAGCTTAAACAGCGATAATTGA
Protein Sequence
MSSITNSEASTSMFDNGLTLEFGPLETVHRWNRMPECDEFVGARRSKHTVVAYKEAIYVFGGDNGKCMLNDLLRFDVKETSWGRAFATGCPPAPRYHHSAVVHNTSMFVFGGYTGDIHSNSNLTNKNDLFEYKFYTGQWVEWRFVGKTPVPRSAHGAAVYDGKLWIFAGYDGNARLNDMWTISLNDDSHTWEEVEQKGECPPTCCNFPVAVARECMFVFSGQSGAKITNSLFQFNFKTKTWTRISTEHILRGAPPPPARRYGHTMVAFDRHLYVFGGAADSTLSNDLHCFDLDSQTWSVIHPARDSVVPSGRLFHAAAVVGDAMFIFGGTVDNNVRSGEMYRFQFSNYPKCTLHDDYGKILESKEVCDVQFIVGAEEIKILAHLALVAARSLYLRNKIRQAKEARDRHLEMFFGTIKVSFSDIPLLEVKLRDANSEAFEMVLNYIYMDCIDPTKKAKQGEDPFSNRIVLLMMDVYRLAVQFDMARLEHLCVQYLGATICLKNVLEALHNADKLHLDFIKEFCLRFIVKDPNYNSIVMSKEFEDLDRGLMVEIIRRKQVPQPKVHIESTFDTAGSSLEQDMAMFLQTTGKEFCDIDLVLDEVVIPAHKTILAARCTYFEGMFRSFMPSDNRVRIQIGEMTPSRESFDSLLRYIYYGDINMPPEDSLYLFSAPFFYGFSNNRLQAFCKQNLEMNVTFENVIQILEAADRMQATDMKKFALDLIVHHFTKVAKLPKLKMLSKELILDILTALANDMSDPKMCQDVSSISLNSDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01186316;
90% Identity
iTF_00838703;
80% Identity
-