Alei014756.1
Basic Information
- Insect
- Aquatica leii
- Gene Symbol
- -
- Assembly
- GCA_035610365.1
- Location
- CM069432.1:139243317-139250481[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 5.3e-18 1.3e-13 53.0 0.0 4 74 380 451 378 454 0.93
Sequence Information
- Coding Sequence
- ATGGCTGAAACAAAAcatgaaatttgtttaaaacatgtcATAGAAGTGACATCTAGGGCTAGAtgTGCTGCATTAGAAGGAAACAACGATCCCAGCACAATACTAGGTGGTGTACGATTACCTCCAgatacagaaataataaaatacacatcGTCTATAGTGGGACCTAAAATACCAGGAACTACGAATAGAGGAAGGAAAAAGACAATATCTCTTGATCCGCCTTCAGTTAGCGTTCATCCCTCTTTATCAAGTGGAAGTATGCACATCGAAAGAGCAGCCAAACGTCCTAAACTTAGCGAGTCGCAAGATTCTTCAACTTTAAACGCTTCCAACGATCGAGTAGAAGTTATAAAGTTAGCTCCAACTAATGGTAGTCCCGTCATGCCAAATTCcacgtataataataataataatagtggATTCTCCGAATCAATTGGGGGCGATACACCTTTAAATTTATCGATGAAGCCAAGCTCTACTAACTTAACTAGTTCTTCATTAAACTCTCTTAGTAATATGTCTGCGAGTTTAGGAGTGGATAGAATTTcGAGAAGAAAACCAGGCCCTAAACCTCGAAAAGTAATTCAATCTTCATGTCATCCACCTCCAGCAACGCCAAGTGCATCATTACAACAATTATTTGCATCTGCAGACTCTCCAAGATCTCCAACGCGATTGGATGATAGTTTAAGTACTACAACAGCAATAACATCGACTAGCTCGTCCACCATTGGATCTCTTCCAATTCCAATACATAAAGATGGGAGGCCTCGTAATTTGGGCAGAGGAATAAGTAAACCTAAGAAAAATACCGTAGCCTCTCTTTTAGCCCAGAGTAGGGCTTTAGGCATTAAACCTATGCAAGTTTTGGACCCAAATGCTTCAATGAATCAGCAGATTACGTTACTAAAATCGAATATATTGGCCGCGCAACAGTTAATGGTTGAGGCTGGTGGTGACGAAAAGactttcaataaacttttacagGAAAAATTTAGGGGTGCTCTAAGTGATTCTAATTCCAGTACTGTAGATGCATCAACAGATTCTGATAATCTTACAGATTCAAATCACACGGATTCTGAAATGGAGACTGATTCTTCCGTTACAGTTAGAAAACCAAAGCACTTTGACGAACGTGCACTAAAAGTTCCTCTCGATAgagGTTGGAAACGAGAGACTGTAATTAGAGGATTGGGTAAAAATGGTAATATCAAAGGTGATGTTATTTATATTGCCCCAGACTCTTCTAATAAGTTTAAACAAATGTCGGATATTACACAGTATTTAGATTATCAGGAAAACACTGATTTGACAAAAGAGAATTTTACATTTAGTAGTCGCGTTATTCTTGGTGATTATCTCCAACCTGTTCCATCAGGTATGGTTCCAGAAGGAGGTGAATTTATCCGTTTAACTGAGGATGATGTAAATAGGAGGTTAGAAGAATTAAAATCTGTGACACGCACTAATTTAGCTGTTGAACAACGAATAGAAGTTGCTAGAAGACAACAAGCAGCACGTGCTCAAGCCCGAATGGAAAAAGAACAGGCTAGGTTGCAAAGAGAAATGGAAAGATCTGAAAGACAAGAAGCGGCGCGTAGAGAAAGAGAAGCTCGATCTCAACAATTGTTAGAGGGTCGCAAACGCCTAGCATTCAGTCTTGAACAGAAAATACGTATAATATCAGAAATAGAAGGGGGAAAGACAAAATCGGATGTATCTCGAGAATTAGGTTTGGCTAGTTCAACCGTTGCTACAATTTGGAAGAGCCGTGTTAACATTATTAGTGCTTACAATTCTAAAAGCTTTGATcaagatttaaatataaaaaacgctTCCGTAATTAAAGATTTTGAAGATCTTAAATCTAAATACCCCGCTCTTAATTGCTCCATTAGTAATGTGGTAGGttaa
- Protein Sequence
- MAETKHEICLKHVIEVTSRARCAALEGNNDPSTILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPSVSVHPSLSSGSMHIERAAKRPKLSESQDSSTLNASNDRVEVIKLAPTNGSPVMPNSTYNNNNNSGFSESIGGDTPLNLSMKPSSTNLTSSSLNSLSNMSASLGVDRISRRKPGPKPRKVIQSSCHPPPATPSASLQQLFASADSPRSPTRLDDSLSTTTAITSTSSSTIGSLPIPIHKDGRPRNLGRGISKPKKNTVASLLAQSRALGIKPMQVLDPNASMNQQITLLKSNILAAQQLMVEAGGDEKTFNKLLQEKFRGALSDSNSSTVDASTDSDNLTDSNHTDSEMETDSSVTVRKPKHFDERALKVPLDRGWKRETVIRGLGKNGNIKGDVIYIAPDSSNKFKQMSDITQYLDYQENTDLTKENFTFSSRVILGDYLQPVPSGMVPEGGEFIRLTEDDVNRRLEELKSVTRTNLAVEQRIEVARRQQAARAQARMEKEQARLQREMERSERQEAARREREARSQQLLEGRKRLAFSLEQKIRIISEIEGGKTKSDVSRELGLASSTVATIWKSRVNIISAYNSKSFDQDLNIKNASVIKDFEDLKSKYPALNCSISNVVG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -