Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0086 1e+02 4.8 0.0 32 47 14 29 6 33 0.80

2 10 0.0083 97 4.9 0.0 32 47 41 56 32 60 0.80

3 10 0.0079 93 4.9 0.0 32 47 68 83 58 88 0.81

4 10 0.0086 1e+02 4.8 0.0 32 47 95 110 87 114 0.80

5 10 0.0016 18 7.2 0.0 32 47 122 137 113 143 0.81

6 10 0.0082 96 4.9 0.0 32 47 149 164 141 170 0.81

7 10 0.0076 89 5.0 0.0 32 47 176 191 164 196 0.81

8 10 0.0078 92 4.9 0.0 32 47 203 218 191 222 0.81

9 10 0.0078 91 4.9 0.0 32 47 230 245 220 251 0.81

10 10 0.025 3e+02 3.3 0.0 32 45 257 270 248 273 0.81

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0086	1e+02	4.8	32	47	14	29	6	33	0.80
2	10	0.0083	97	4.9	32	47	41	56	32	60	0.80
3	10	0.0079	93	4.9	32	47	68	83	58	88	0.81
4	10	0.0086	1e+02	4.8	32	47	95	110	87	114	0.80
5	10	0.0016	18	7.2	32	47	122	137	113	143	0.81
6	10	0.0082	96	4.9	32	47	149	164	141	170	0.81
7	10	0.0076	89	5.0	32	47	176	191	164	196	0.81
8	10	0.0078	92	4.9	32	47	203	218	191	222	0.81
9	10	0.0078	91	4.9	32	47	230	245	220	251	0.81
10	10	0.025	3e+02	3.3	32	45	257	270	248	273	0.81

Coding Sequence: ATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAGGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACATGGCGACGTACGGTAGTCTTTCCCCCATCCAAGGGACAGTAGTAACACGACAAACGAAGACGGTCAAACGACATCTCAACGCTTGCGCTAGCAATCCAACATGTTGGGAGGAGCTTGCTGCTAATAGTTCATCTCGATCTACCATCTTTGAGCATAAATCAAAACGTTTGAGGAAAATCACCTCACAACTCTAG
Protein Sequence: MATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTRTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNMATYGSLSPIQGTVVTRQTKTVKRHLNACASNPTCWEELAANSSSRSTIFEHKSKRLRKITSQL*

Sequence clustering based on sequence similarity using MMseqs2