Anig013546.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aporophyla nigra
Gene Symbol
Rfx2
Assembly
GCA_947507805.1
Location
OX382295.1:5413090-5450158[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.7e-37 2.4e-33 115.2 0.0 3 78 228 303 226 304 0.97
2 2 1.9 2.7e+04 -3.5 0.0 24 32 892 900 880 907 0.69

Sequence Information

Coding Sequence
ATGTCTGAGATGGGCTTTGAGAATGTGTTCTATTTAGAGAACTTTGAGTGCGCCGGCGACGAGGTACTGGTGGAGTCGTCGCCGCCTGCATCACCTGACATGGCAGCGCGGCTCGCGGCTCCTCCACAGGGTGGCGCGGGCGGCGGTGCCTCGCCGAGCGCTGTGCGTGACCTCATCGTAATACCGGAAATACCCGACTCCATACATTTGCAGCACGCAATGCAACAGGTAACGAGTACGGTGGTGGAAGTGAATGGCGACAGTTCCGGGCACTCCAGCCCCACAGCTGAGGGACAGCACACTTACATCACTGTGGCGAGCGAGTTGCAAGGCGCATGGGCACAGCCAGGCACCCACGTGAAGATTGAGGAACAAAGTGACCAAGAAAGCGAGGGCGGTAACGGCGTCAACTATCACGTGCAGTATGTGACGGAGCCGCAGGAGATCTACACACAAGGTCACCCGACGCATATGGATTCTTTGCGCTCCTACCCCGTGTATGGAGTGGCGACCGTGAGCAATGGAACGAGCGCGGAAGGCACGTCTGCGGACAACGGCTGGGGCGGAGCCTCTTCCGCTGAATACACCGCTTATGGCGTCGTGGTGGCCGGCGACGAGGCGTCGGCGCCCGCGTCGCCCGCCACGCCGGCCGGCGCGCCCACCGCGCCGCGCATGCCGCCCGCCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGGCGTCTCCCTGCCCCGCTCCACACTGTACGCGCACTACCTGCGCCACTGCGCGACCCACCGCCTGGAGCCAGTCAACGCAGCGTCCTTCGGCAAGCTCATACGCTCCGTGTTCATAGGCCTTCGCACTCGGAGACTGGGGACCAGAGGGAACTCCAAGTATCATTACTACGGGATTAGGGCGAAGCCCGGCGTCGAACACGATCATAGTGAGAGCGATTTGAATGACCAACAGGATAATTCGGATGATAAGACCGATGTACTGGATCATCAGGAGGGTAGATCCCGCGAGCGATCCCGCGACTCAGCGAGCAGCCCGAACCACGCGCACCGGCAGTTCCTGGGCTCCGTGTCGGCGCCCGAGCCGCCGCCGCTGTCTGTAGAGCCACTGCCTGACGACGTGCCGCCCGAGGCTCTCCATGCGCTGCGGAGACATCACAGGGAGCACGGCGCGGAGTTCCTGTCGGCCGTGGCGGCGCTGGACACGAGCGCCGTGGAGCGAGCGCGCCGCGCCTTCTGGCGCCGGCCGCCGCCCGCGCTGTGCCGCCGCGTGCTGTGCCGCCTGGCGGCGCGCAAGGACGTGGCCGCCTGGCTGCGCGCTGCGGAGATGCAGCTGTACCAGCGTGCCGTCGAGCTGCTGCTGCCCGACGTGCTGCGGCCCATCCCGCCACAGCTCACACAGGCGATCCGCAACTTCGCGAAGAGCCTGGAGGGCGCGCTGGCGGCGGGCGCGGGCGGCGCGCCGGCGGCGGCGGCGCGTGCGCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGGCGCAGGCGGCGGGCGCGCTGGCCGCCGCGCTGCGCCGCTACACGTCGCTCAACCATCTGGCGCAGGCCGCGCGCGCCGTGCTCAACAACCATCTGCAGATACACCAGATGCTAGCGGACCTGAACCGCGTGGACTTCCGCGTGGTGCGCGAGCAGGCGGCGTGGGCCTGCTCCTGCGCCAGCGCCGCCACTGCGCACAAACTGGAAGCGGACTTCAAGGCCACATTGGGACGAGGAGCGTCTCTAGAGCAATGGGCTGGTTGGCTGGAAGGCTGCGTGCGAACCGCCCTAGCTCCGCACGAGCGTCGGCCTGACTACACGGCGAGGGCACGCCGCCTGCTGCTGGACTGGTCCTTCTACTCTTCGCTTGTCATCAGAGAACTCACTCTCAGGTCTGCCGCGTCGTTCGGCTCGTTCCACCTGATCCGCCTGCTGTACGACGAGTACGTGTCGTACCTCATCGAGCGCCGCGTGGCCGCGCACCACGACGCGCCGCCCATCTCCGTCATGCAGAGGGCACTCGAACAAGATGAAGAAGACATCCCTGAGGAGCCGCCTCGCGAGCTGGACGATGACGAACAAGAGTGGGAGTGGGACGATGACGAGGAAGAGGATGACGAGCCGGAGTGTAAGAAACAGAAGATAGCCGCCGAGTAG
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPDMAARLAAPPQGGAGGGASPSAVRDLIVIPEIPDSIHLQHAMQQVTSTVVEVNGDSSGHSSPTAEGQHTYITVASELQGAWAQPGTHVKIEEQSDQESEGGNGVNYHVQYVTEPQEIYTQGHPTHMDSLRSYPVYGVATVSNGTSAEGTSADNGWGGASSAEYTAYGVVVAGDEASAPASPATPAGAPTAPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCATHRLEPVNAASFGKLIRSVFIGLRTRRLGTRGNSKYHYYGIRAKPGVEHDHSESDLNDQQDNSDDKTDVLDHQEGRSRERSRDSASSPNHAHRQFLGSVSAPEPPPLSVEPLPDDVPPEALHALRRHHREHGAEFLSAVAALDTSAVERARRAFWRRPPPALCRRVLCRLAARKDVAAWLRAAEMQLYQRAVELLLPDVLRPIPPQLTQAIRNFAKSLEGALAAGAGGAPAAAARAQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQAQAAGALAAALRRYTSLNHLAQAARAVLNNHLQIHQMLADLNRVDFRVVREQAAWACSCASAATAHKLEADFKATLGRGASLEQWAGWLEGCVRTALAPHERRPDYTARARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVAAHHDAPPISVMQRALEQDEEDIPEEPPRELDDDEQEWEWDDDEEEDDEPECKKQKIAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00757874;
90% Identity
-
80% Identity
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