Ahis008784.1
Basic Information
- Insect
- Apocheima hispidaria
- Gene Symbol
- br
- Assembly
- GCA_947579745.1
- Location
- OX388147.1:7662927-7666644[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.7e-29 5e-27 94.5 0.5 1 109 22 126 22 127 0.94
Sequence Information
- Coding Sequence
- ATGAATAATGcgccgcaatattcactacgctggaataattacgtatcccacgtaacagaggctttcaatgtcctccgattcgagaacgacttggtggacgtgaccctgtgttgtgacggaggcaaaataaaagctcataaaatgttgctgtcagcttgcagcaattacttcaagcaaattttcaaagagaacccttgccaacatcctgtgataatattcagaaatttcaagtacgaagacctcaatgcaattatcaatttcatgtatcatggagaagtgaatatctttcaagaacaactggagtcattcctcaacacagctgagcttttagaggttaaaGGTTTGACTGATAATGTGGAGGAGGAAGCGTCTCAAAAGTTAATGAGAATAAGTGACAATACATCCCTAGATTTAAGTGCTAAGTCGAGTAGATTCCCTGAAGACATCGTGCCTGTTCTCTCTGACGAGCCAATAAACTTGGCAACTATGCAGTCTGTAAGAGAGGAGTACATTCCACAAGTGAGCTCTGTGACGCTCGTGCCTGATCCAGAAAATGGTGCTATAGAATTACTGCAAGAAACTTCAAAAGTTGAGGAAAGTGTGAGTCCAGGACAGAAAGCAGCGACCCCACCGAGTGAGGACATGCAGGTTGACATGCAGTCAACTTCAGCTGAAGATTTAACAGAGAAAGGTACTTCTGAATCGGATCTGGTGAAGTTTCGCTGTCAACTATGTCCGAAAGGCTTCAAGCATCCCACTTCTTTAACTCTCCACAAAGATTCTCACGCTGGAAAAACACAGTGTCCGGTCTGCCACAGATCGTTCTCCAGATCCTACGATATGAGAAGTCATCTGCAACGGATACACCAAGGGAAGCAACTGACTATCAAAGAGATCAGATATAAAAATAGTAGCGATAGCACAACTCCAAAACAATTCACCCATAACATATAG
- Protein Sequence
- MNNAPQYSLRWNNYVSHVTEAFNVLRFENDLVDVTLCCDGGKIKAHKMLLSACSNYFKQIFKENPCQHPVIIFRNFKYEDLNAIINFMYHGEVNIFQEQLESFLNTAELLEVKGLTDNVEEEASQKLMRISDNTSLDLSAKSSRFPEDIVPVLSDEPINLATMQSVREEYIPQVSSVTLVPDPENGAIELLQETSKVEESVSPGQKAATPPSEDMQVDMQSTSAEDLTEKGTSESDLVKFRCQLCPKGFKHPTSLTLHKDSHAGKTQCPVCHRSFSRSYDMRSHLQRIHQGKQLTIKEIRYKNSSDSTTPKQFTHNI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01172508;
- 90% Identity
- iTF_00143512; iTF_00650499; iTF_00650146; iTF_00055557; iTF_00666636; iTF_00666988; iTF_00056153; iTF_00635525; iTF_00045000; iTF_00927117; iTF_00044623; iTF_00926740; iTF_00635898; iTF_00827597; iTF_00827118; iTF_00825918; iTF_00826430; iTF_00206213; iTF_00207463; iTF_00206606; iTF_00207100; iTF_00125222; iTF_00125537; iTF_00818438; iTF_00818764; iTF_01172880; iTF_01172508; iTF_00390525; iTF_00390919; iTF_00896050; iTF_00896394; iTF_00033429; iTF_00033028; iTF_00034325; iTF_00033930; iTF_00649241; iTF_00649621; iTF_00936189; iTF_00935845;
- 80% Identity
- iTF_00143512;