Basic Information

Insect: Apis mellifera
Gene Symbol: Prdm15
Assembly: GCA_003254395.2
Location: NC:12368585-12371265[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 7.5e-05 0.0046 16.5 5.0 1 23 246 268 246 268 0.97

2 12 0.016 0.98 9.1 6.5 1 23 273 295 273 295 0.97

3 12 0.00053 0.033 13.8 1.4 3 23 306 326 305 326 0.98

4 12 0.00051 0.031 13.9 6.6 1 23 416 438 416 438 0.99

5 12 0.0012 0.072 12.7 1.9 1 23 443 467 443 467 0.90

6 12 7.2e-07 4.4e-05 22.8 1.0 1 23 506 529 506 529 0.96

7 12 1.2e-06 7.3e-05 22.1 1.1 1 23 563 585 563 585 0.98

8 12 0.00011 0.0066 16.0 4.0 1 23 599 621 599 621 0.96

9 12 0.0001 0.0062 16.0 4.7 1 23 627 649 627 649 0.98

10 12 0.00091 0.056 13.1 3.2 1 23 655 677 655 677 0.98

11 12 6.4e-05 0.0039 16.7 6.6 1 23 683 705 683 705 0.97

12 12 0.00014 0.0088 15.6 0.3 1 21 711 731 711 732 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	7.5e-05	0.0046	16.5	5.0	1	23	246	268	246	268	0.97
2	12	0.016	0.98	9.1	6.5	1	23	273	295	273	295	0.97
3	12	0.00053	0.033	13.8	1.4	3	23	306	326	305	326	0.98
4	12	0.00051	0.031	13.9	6.6	1	23	416	438	416	438	0.99
5	12	0.0012	0.072	12.7	1.9	1	23	443	467	443	467	0.90
6	12	7.2e-07	4.4e-05	22.8	1.0	1	23	506	529	506	529	0.96
7	12	1.2e-06	7.3e-05	22.1	1.1	1	23	563	585	563	585	0.98
8	12	0.00011	0.0066	16.0	4.0	1	23	599	621	599	621	0.96
9	12	0.0001	0.0062	16.0	4.7	1	23	627	649	627	649	0.98
10	12	0.00091	0.056	13.1	3.2	1	23	655	677	655	677	0.98
11	12	6.4e-05	0.0039	16.7	6.6	1	23	683	705	683	705	0.97
12	12	0.00014	0.0088	15.6	0.3	1	21	711	731	711	732	0.93

Sequence Information

Coding Sequence: AtggaaatcgaaaataaaacatcaattttatcaaatgataGTGGCAATGTTTGCCGCGTTTGTCTTGCAACAAATCAAAATAACCAATGCATTTTCAATGCTAAACAAAGTAATTCTATAGACGAAGATACAATTGATTTATCTGAAAAACTTCGCTTGTGCAGTGGTGTAGAGATATTAGAAAATGATGGTTTACCTTCCACTATTTGtatgaaatgtatattaaaaattaatgatgctCATGAATTAAGACAACAGTGTCAACAATCTGATATCCAATTAAGAGAATTATATGGTaaagtggaaaaaatatataatattaacttatgTAAGACTACAAtagatCAATATTGTCAAACTGATTATTCTTTTACttctgatttaattaaaattgaaactgcAATGGGCTATAATCCTTATTCAATGATAATTGTTAATTCagatactaaaaatataaaagataatgaaatgattaatGAATCAAAATATGTAGAAGATAAAGAATCTAAtagcaatttaaataaacaaaatggttacataaaatgtaaacaaacagaatatgaaaaaaatattacaggaAGAGAAGTTtatcgaacaaaaaaaatgacaatgtTTAAAAGAGTaacatttatagaaaatttaaaaaatcataaggAAAGACAAAGGCAgtacataaaaaagaatacaacTGTTAAATGGGATAATGATGcaacagatattaaaaaaaaagattctcatATTTGTCCAAAATGCACAAGATGCTATTCTAGCAAAAGATCTTTGGATAGACATATTTTGACTCAtgatgaaaaaagatttacatGTGATAAATGtagcaaacatttttttcatcttgataaattgatacaGCATAGCAAATTGCATATGATTAAGGAAAAACCTAAACCAGTACtatgtaaaatatgtaatagaaattttagaaaaactgATACTATGGTAAGACATTTAAATGTTCATAAAAGAACTAATCCAAAAGAAGTTCTTTCCATTCTAAAGGaaataagagataaaagaaaattggaaaatattgaaccagaaaagaagatttttgaagctgaaaataataaaaatataaaagcaatagaagaagaatttataactaatgaaaatattattttaaatatccataaaaaaaagacattagaatctaatgataaaaaatccaattcaaatttatcagaTATTAGTGctgaaaatattgattctttTAATCATGAAACACTTTACCGATGTAATTATTGTACTAAACATTGcgcaaatgaaaaatcatttcaaaaacatatacaaattcatattgaaaaaaaatttgtttgcaatgtatgtaatatgaaattttttcgtcAAGATAGATTAAATAGTCATAAGAATCGATATGGACATGATGAAAAGGCAGTATCATTAGAAACACAAAAACCATGTGATGATAAATCagctattaaattaataaatagttgGATTAGAGAGGAACTTGATTCAGATAATGAAGAAAAGGGTTTTCCTTGTAAAATTTGTGGAAAATCatatgatacaaaaaaatctttattaaaacatcAATTGAGTATGCATaatggaggaggagaaaaaaactgTCTGACATGTGGTAAAATGTGTACTTGtgatgagaaaataaaaaatcaagataaaccaaatgaaagattaaaacCATTTCGATGTGACGAATGTAATAAAtcctttgaaaaagaaattaaattacagaAACATATAAGAATTCACGAACGTGCTAAAGAACAACaagatgtaaattttaaacgatttttatgTCATATATGTAGCAAGACTTTCAGGCAAAATACAGGTCTCATGTTTCATATGAGAACACATACAGGCTATAAGCCTCATGTTTGCAAATATTGTGGAAGAGGATTCACATCAAATTCTAATTGTATTAATCATGAAAGAACTCATACTGGTGATAGACCATTTGTTTGTCATTTCTGTAGTGCTGCTTTTGCCAAATCATGTACACTTAAAGCACATATTACAACACATACTGGAGAAGCAAATTATCATTGTAAAACGTGTGGTAAATCATTTAGAAGATTAAAATACCTGAAAGAGCATAAATTCACGCATACGGGAGAAAAACCATATGCTTGTAAAATTTGTGGTACAGCATATAGTCATTCTGGTAGTTTATTTGTACATGAGAAAAAATGTAAAGCACAATATAATAGCTATCAATCTAATTCAACACAAAGTATGCAAGCTTACTGTGAATCTGATATTTCTTCACCAAGTGTGACTCCTATTATCACAGTATTACCACAAATGTATCTAAATAATACAAGTTCCATGAATACACAAAATAGCAAaagttatattgataatattcaaaagataaattctCAGAATATTACCAATGGAAATGCTGTTAACACATCAGATTTAcatattcattcaaattctGATATTTCTGATGTTTCTTTAGCTGTAAAAAGTTTTGCTCTTATTGGACaaatgtttcaataa
Protein Sequence: MEIENKTSILSNDSGNVCRVCLATNQNNQCIFNAKQSNSIDEDTIDLSEKLRLCSGVEILENDGLPSTICMKCILKINDAHELRQQCQQSDIQLRELYGKVEKIYNINLCKTTIDQYCQTDYSFTSDLIKIETAMGYNPYSMIIVNSDTKNIKDNEMINESKYVEDKESNSNLNKQNGYIKCKQTEYEKNITGREVYRTKKMTMFKRVTFIENLKNHKERQRQYIKKNTTVKWDNDATDIKKKDSHICPKCTRCYSSKRSLDRHILTHDEKRFTCDKCSKHFFHLDKLIQHSKLHMIKEKPKPVLCKICNRNFRKTDTMVRHLNVHKRTNPKEVLSILKEIRDKRKLENIEPEKKIFEAENNKNIKAIEEEFITNENIILNIHKKKTLESNDKKSNSNLSDISAENIDSFNHETLYRCNYCTKHCANEKSFQKHIQIHIEKKFVCNVCNMKFFRQDRLNSHKNRYGHDEKAVSLETQKPCDDKSAIKLINSWIREELDSDNEEKGFPCKICGKSYDTKKSLLKHQLSMHNGGGEKNCLTCGKMCTCDEKIKNQDKPNERLKPFRCDECNKSFEKEIKLQKHIRIHERAKEQQDVNFKRFLCHICSKTFRQNTGLMFHMRTHTGYKPHVCKYCGRGFTSNSNCINHERTHTGDRPFVCHFCSAAFAKSCTLKAHITTHTGEANYHCKTCGKSFRRLKYLKEHKFTHTGEKPYACKICGTAYSHSGSLFVHEKKCKAQYNSYQSNSTQSMQAYCESDISSPSVTPIITVLPQMYLNNTSSMNTQNSKSYIDNIQKINSQNITNGNAVNTSDLHIHSNSDISDVSLAVKSFALIGQMFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01418508;
90% Identity: iTF_00140775;
80% Identity: -