Basic Information

Insect: Apis mellifera
Gene Symbol: gtf3a
Assembly: GCA_003254395.2
Location: NC:11837276-11843338[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.3e-05 0.0032 16.9 0.1 2 23 743 764 742 764 0.97

2 16 0.6 36 4.2 1.5 3 23 798 818 797 818 0.97

3 16 0.00018 0.011 15.3 1.2 3 23 827 848 826 848 0.98

4 16 0.0018 0.11 12.1 2.0 1 23 855 878 855 878 0.95

5 16 6.3e-05 0.0038 16.7 0.7 1 23 884 907 884 907 0.94

6 16 0.87 53 3.7 2.5 2 23 915 935 915 935 0.94

7 16 9.3e-08 5.6e-06 25.6 2.1 2 23 941 962 940 962 0.97

8 16 1.5e-06 9.1e-05 21.8 0.2 1 23 968 990 968 990 0.99

9 16 0.00037 0.023 14.3 2.4 2 23 1002 1024 1001 1024 0.95

10 16 0.0053 0.32 10.7 2.5 1 23 1030 1053 1030 1053 0.96

11 16 0.017 1 9.1 3.8 3 23 1076 1097 1075 1097 0.95

12 16 0.00078 0.047 13.3 1.4 2 23 1104 1126 1103 1126 0.96

13 16 2.6e-05 0.0016 17.9 1.0 2 23 1134 1155 1133 1155 0.96

14 16 0.00081 0.049 13.2 2.3 1 23 1161 1184 1161 1184 0.96

15 16 0.22 13 5.6 3.2 2 23 1191 1212 1190 1212 0.96

16 16 0.0064 0.39 10.4 2.6 1 23 1218 1240 1218 1240 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.3e-05	0.0032	16.9	0.1	2	23	743	764	742	764	0.97
2	16	0.6	36	4.2	1.5	3	23	798	818	797	818	0.97
3	16	0.00018	0.011	15.3	1.2	3	23	827	848	826	848	0.98
4	16	0.0018	0.11	12.1	2.0	1	23	855	878	855	878	0.95
5	16	6.3e-05	0.0038	16.7	0.7	1	23	884	907	884	907	0.94
6	16	0.87	53	3.7	2.5	2	23	915	935	915	935	0.94
7	16	9.3e-08	5.6e-06	25.6	2.1	2	23	941	962	940	962	0.97
8	16	1.5e-06	9.1e-05	21.8	0.2	1	23	968	990	968	990	0.99
9	16	0.00037	0.023	14.3	2.4	2	23	1002	1024	1001	1024	0.95
10	16	0.0053	0.32	10.7	2.5	1	23	1030	1053	1030	1053	0.96
11	16	0.017	1	9.1	3.8	3	23	1076	1097	1075	1097	0.95
12	16	0.00078	0.047	13.3	1.4	2	23	1104	1126	1103	1126	0.96
13	16	2.6e-05	0.0016	17.9	1.0	2	23	1134	1155	1133	1155	0.96
14	16	0.00081	0.049	13.2	2.3	1	23	1161	1184	1161	1184	0.96
15	16	0.22	13	5.6	3.2	2	23	1191	1212	1190	1212	0.96
16	16	0.0064	0.39	10.4	2.6	1	23	1218	1240	1218	1240	0.98

Sequence Information

Coding Sequence: atgactaGATCAAAAATGCAGCACactgaaattaaaaacaagGATCATAATTATAGTGAAGTAAAATTGCATAACCTTCAACATATTGGtagtaatattcaaaatgcaTATGACAATGATATTAGAACAACATATAAATCAAACAAATCTGGTATAATATCAAACAAAGAAGTATTTggtcaaattaaaaatattaatgaattaaaaagaataacacCGCGTGTAAAATTATTGACTCATGATGCAAATAGCTTAAATGAATTAACTAAAATTTCTTTGCACAATAAAATATCTGcacaaaagaaattatcaatattggaACAAACAAAACaggaattaagaaaatattgtagaaCTTGTGCTGGTTTAAAACTTCCGTTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTcaacaaataaaacatttgGAAGAAATAAATCCATATGATAGTTTATCAACTCAAATGTGTATGGATTGTATTTGTGACTTAAAAATgagctataaattttttatgcaaattaagaAAGcagaagttaaattaaaatctattcatATTACTCTGACTGATACAgcaacaaaaaatatagaattaaataaaattcaacctgtaggaaattttgaaaagcaaACGGAGAATGTTGTTGAGAGTATTGCAACAAATCCATCTAcaagtaaagaaaataatgaacatGCTTCTGTACCAAAAATATCTGCAatcttttcgttaaaaaaaaatgatcaagaGCTTTCAAAAAGTGGAAAagtaaatcttgaaaaatcaGAAAGTAAAACTGAactcgaaatttttgaagattcaACTATTCTACAAAACAGTGATGACAATGAATCTATAGAAGAGTTTGATCCAGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGATTCTGATGATGAAGTAGTAATACCAAATGCAAAAAGACGacattttcaacaaaaagaaaacatcAAACAAAGTTCGCAGTCAATTTTTGTTTccgataataattcaatatcagataataaaaatattgattgtaaTCAAACgacatataattatgatacgcgtttaaaaacatatattaaaatagaagataCAGAGAGTAATAATCAATCTATTGAATCACATAGCATCATTAATTctgaaactatatataatactgaAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAGCGCAgattattattgcaaaataaaaaaggatccATAGAAGAAactgatgaaaatatttgtcagTCCAATATTTCTGATAAAACTGGAAgtcataaagatttaaaagtaCAAAAACTAGatgttaataattctttaaacatTAACAGCAATCAAGAAGATGGGATTATGTATGTTACAGTGAAAGGATCTAAACCAAATGAGATATTGTTagtgaaagttaaaaaaatggataaaccATTAGAGAAAAAGGATGATAAATCtacattgaagaaaaattttgacattaaaccaatggaaaaaattttaaaacgatatgAAACATTAgctacaaaagaaaaagatttattttcagaacGAACAAAAAAATCCGAAATAAGAGAACAGATTATAGAAGAgcaaatagaagaatataagaaaaagcgAGAAAAAGTATTAGGTGGACATGCTAATATTTCGCATCCTTTAAAACTTGAAGAATCTCAAACTCGTTATTTTAAGCGTAATGAAAGGCAAGATAATCAAAGTTCTTTTACACATATAGAGAATGATACTGTTATAGACATACAGTTTAATAAAGatgataatgaatttaatgaaaacgTTAAAATTGAAGATGATACTTCAGAAATTATAGAATCGGTCAAAGAAAAATCTACTAATGAAAATGCTTATGTAAATACCGAAGAGTATTTATCGCGTTTAGCAAAACTTAAGTTGAAATGGGAAgaagcaaaaaagaaaaaagaatctcttCAAAAAGAATTAGATGAATCGTATACGGaaggaaatattgaaaaattaacaagaattttaggagaaaaagaaaaaaatttacaagattttcaagaatacttaaaacaaagtaaaattgtaattacaagattaaaagatgaggatattatttctctttatgaAGATAGAAATAACGCAgtgcttaaaaataatttacctgATTTGATAGACGAAAGTCAACCAGCAGATTATATTCCAGAGGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCTTCAAAAGATGTTCTTGAAGAACATTTGAAAATGCATGACTATAAAATTATGCATTTTTGTGAAGATTGTATGGAAGAATTTCCAACAAATAAAGCAAAACGCAATCATAatgtaatttgtataaaaaaattattatgtaaatattgtgACATGATGTTAGattcaaaaggaaaaaaacgtcAGCATGAACAAAAACATTGTGACAGTATGTATGGACAATTATGCGATGTATGTGGTGAAAAGTTTAAACATCAAGGGACATTAGATCAACATGTAAAAACACAACACATGAGttgggaaaaaatatatcaatgccCAAAATGTCCTAAAAAGTTTGCATTCAAACAAAAACTtagttttcatttgaaatctGTACACACAACATTAAGAGCCTATTTGTGTGAAGATTGTGGAgctgattttaaaaatcctgCAAGTCTTAGACACCATAGAATACGTAAACATCAACCTGTTGGTAATAAAAGAGAATGCCCTGTTTGTCATAAATTAGTACCATTTTATAGTCTTTCAAAGCATATGCATACTCATAAAGCATATACTATCCAGTGTCCACACTgtgataaaatgtttaaaaatagttcAACTTTAAAACAACATGTAAGAATTCATGAAGATCAACGCCAATATCGATGCGATACTTGCGGTGTTGGATTTAATAGACGAGATGGTTTAAGATTACACATGAGAGTACATGAGAAAACTGATAGTAGAGGGTTAAAAGAATGTTCGTGTCAAGTATGCggcgaaaaatttccaaatcacTCAACACTTGTTATACACAGAAACCGAGTTCATAAGGATGGTAGACAATATACATGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAATGGCATATGTCTCACATACATAATGAATTGCTTCCTGGTGTTGTAAAGGAAGATATAGATGGACCaccagaaaagaaaagagcatCGTGTTATCAttgtaataaaacatttaaaacagAAATGATTTTGAGgacacatattaaaaatacacataTGGAAAAAGATCCTATGAAATGTTTAGATTGCGAACTAACATTTACATCTGAAGTAAGATTAAGACATCATATGATGGTTACACATAACAGATTAGAAGGAACTTTGCCATGTCCACATTGTCCGAAGAGATTTGTAAATCAACTCAGATTAAAAACTCATATGATATCTCATTCTGAAGAAAGGCCATACACTTGTGAAATCTgtggatttaatttaaagactAAAATACAGTTGATTAAGCATCATCAAAATAGACATAGTGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCTCTTGTATGTCATGAGAGAACTCATACAAATGAACGACCATATTCTTGTAGTGTGTGTAGACaacgttttaaatatttaggtgataaaaataaacatgaaaGGCGACATGAAAGTTTAGGAGGATCTGGATTTAAAAGAATAGTACTTGGTCGAAATATTAAAGCTAAAGTACAAGAAGATTCTTCTTGTTCTGAGCATGAACAAGAAGTCTTAGCTAATACAGAGCCTCAAGTTCctgaaaatgaatatcaaGAACAAACAGATCAACAATTTGAGGAGGAACAAATAGTTAAGTTCGAAGAAGAGCAAATagttaaatttgaagaagaacAGATAGTTAAATTTGAAGAACAAGAAATAGCAGAAGAATACGAACAAGTATATGaacaagaaTATGAAGAAACATCCAGAGAAGCTTCGGATGCAGCAGAAGTTATAATGAATATGGAAGATACAACTGTTTATACTGAAGAAGTAACTGCAGATAATATTGAACCTGCAGAAATTATGGCAGATGAAATGATGACAAATGAAATACTACAATCAGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGAAAAATACAAGTGATCCCAGTGATGTTATCTTTACCTGATTTAACTGATGCAAATACAGAAGTCAATTTAGCTACTGCatctattatgtataataattga
Protein Sequence: MTRSKMQHTEIKNKDHNYSEVKLHNLQHIGSNIQNAYDNDIRTTYKSNKSGIISNKEVFGQIKNINELKRITPRVKLLTHDANSLNELTKISLHNKISAQKKLSILEQTKQELRKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLKSIHITLTDTATKNIELNKIQPVGNFEKQTENVVESIATNPSTSKENNEHASVPKISAIFSLKKNDQELSKSGKVNLEKSESKTELEIFEDSTILQNSDDNESIEEFDPDDPPFQPDSSDVADSDDEVVIPNAKRRHFQQKENIKQSSQSIFVSDNNSISDNKNIDCNQTTYNYDTRLKTYIKIEDTESNNQSIESHSIINSETIYNTESTKECSKQPNILKRRLLLQNKKGSIEETDENICQSNISDKTGSHKDLKVQKLDVNNSLNINSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKDDKSTLKKNFDIKPMEKILKRYETLATKEKDLFSERTKKSEIREQIIEEQIEEYKKKREKVLGGHANISHPLKLEESQTRYFKRNERQDNQSSFTHIENDTVIDIQFNKDDNEFNENVKIEDDTSEIIESVKEKSTNENAYVNTEEYLSRLAKLKLKWEEAKKKKESLQKELDESYTEGNIEKLTRILGEKEKNLQDFQEYLKQSKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKDVLEEHLKMHDYKIMHFCEDCMEEFPTNKAKRNHNVICIKKLLCKYCDMMLDSKGKKRQHEQKHCDSMYGQLCDVCGEKFKHQGTLDQHVKTQHMSWEKIYQCPKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVGNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNELLPGVVKEDIDGPPEKKRASCYHCNKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFTSEVRLRHHMMVTHNRLEGTLPCPHCPKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIVLGRNIKAKVQEDSSCSEHEQEVLANTEPQVPENEYQEQTDQQFEEEQIVKFEEEQIVKFEEEQIVKFEEQEIAEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPAEIMADEMMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLTDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00734092;
80% Identity: -