Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:7129964-7147478[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3e-05 0.0018 17.7 1.4 1 23 333 355 333 355 0.96

2 18 0.0018 0.11 12.1 1.6 1 20 361 380 361 383 0.94

3 18 7.5e-06 0.00046 19.6 1.4 1 23 389 411 389 411 0.98

4 18 4.4e-05 0.0027 17.2 4.4 1 21 417 437 417 439 0.95

5 18 5.9e-06 0.00036 20.0 5.6 1 23 445 467 445 467 0.99

6 18 1.3e-05 0.00082 18.8 5.3 1 23 473 495 473 495 0.97

7 18 5.1e-05 0.0031 17.0 6.9 1 23 501 523 501 523 0.96

8 18 5e-08 3e-06 26.5 2.7 1 23 529 551 529 551 0.98

9 18 3.7e-05 0.0022 17.4 6.7 1 23 557 579 557 579 0.97

10 18 1.1e-05 0.0007 19.0 5.8 1 23 585 607 585 607 0.98

11 18 3e-07 1.9e-05 24.0 2.9 1 23 613 635 613 635 0.98

12 18 4.5e-06 0.00028 20.3 7.8 1 23 641 663 641 663 0.98

13 18 1.4e-05 0.00087 18.7 9.1 1 23 669 691 669 691 0.98

14 18 1.9e-05 0.0011 18.4 7.5 1 23 697 719 697 719 0.98

15 18 0.0009 0.055 13.1 8.8 1 21 725 745 725 747 0.94

16 18 6.9e-06 0.00042 19.7 0.4 1 23 753 775 753 775 0.98

17 18 0.016 1 9.1 4.5 1 23 785 807 785 807 0.98

18 18 2.6e-07 1.6e-05 24.2 1.3 1 23 813 835 813 835 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3e-05	0.0018	17.7	1.4	1	23	333	355	333	355	0.96
2	18	0.0018	0.11	12.1	1.6	1	20	361	380	361	383	0.94
3	18	7.5e-06	0.00046	19.6	1.4	1	23	389	411	389	411	0.98
4	18	4.4e-05	0.0027	17.2	4.4	1	21	417	437	417	439	0.95
5	18	5.9e-06	0.00036	20.0	5.6	1	23	445	467	445	467	0.99
6	18	1.3e-05	0.00082	18.8	5.3	1	23	473	495	473	495	0.97
7	18	5.1e-05	0.0031	17.0	6.9	1	23	501	523	501	523	0.96
8	18	5e-08	3e-06	26.5	2.7	1	23	529	551	529	551	0.98
9	18	3.7e-05	0.0022	17.4	6.7	1	23	557	579	557	579	0.97
10	18	1.1e-05	0.0007	19.0	5.8	1	23	585	607	585	607	0.98
11	18	3e-07	1.9e-05	24.0	2.9	1	23	613	635	613	635	0.98
12	18	4.5e-06	0.00028	20.3	7.8	1	23	641	663	641	663	0.98
13	18	1.4e-05	0.00087	18.7	9.1	1	23	669	691	669	691	0.98
14	18	1.9e-05	0.0011	18.4	7.5	1	23	697	719	697	719	0.98
15	18	0.0009	0.055	13.1	8.8	1	21	725	745	725	747	0.94
16	18	6.9e-06	0.00042	19.7	0.4	1	23	753	775	753	775	0.98
17	18	0.016	1	9.1	4.5	1	23	785	807	785	807	0.98
18	18	2.6e-07	1.6e-05	24.2	1.3	1	23	813	835	813	835	0.97

Sequence Information

Coding Sequence: ATGGCGTTGACTTCCAATTCGCATCATCAGTCAACACCTacacatcatcatcatcaatcTTCAGTTAGCAGTAGCAGTCATCATAGTTCTTTACAACCAAATCCACAGcaGATACCAGTTTCTCTACCAGGCCTTAATTTAGACGGAGCACATATACCTGCCAGTGTCAGTCATTTACAGGCAGCACATGCACAAATGCAACAACAAATGCAGGCAGCCCAACAGCAACAGCTGCATCAGCAGCAACAAcctcaacaacaacaacaacaacaacagcaacagcaatCTCATCATCAAAtacaaaatcatcaaaatgCTCAGAATAGTGGACCAACTGCACATAATCAAAACGCACAGAGAGATGATAATAAAGTGAAAGATGAAGGTGGAAGTTGCACGACTGAACGTTGCAGTGACAATCAAGTTCACTGTCAAGTTCAATGTGATCTCCAATTACAAACGTCTCAAGATTTGCAACAAAGTCTTatgcaacaacaacagcaacagcaacaaatTGGTGTGAATATAAGTGGAAATTCATCAAGTGAAAGTGGAAGTCAAAATAATACAGAAAAGcctgagaaagaaaaagaactacGTCAATTAAACATGACGCAATTTCAAGTGCCAGATTTAAAACCAGGAGGTCATATGATGGATGTAAGAACAGCTGATGGTTCAGTTGTAAAAATTAGTGCTGGAAATGAACAAGATTTAGCAAAAACGCTTGGTGTTGAAATGGTGCAAAATATGTATAAGGTAAATGTCGAGGATATTAATCAACTTTTAGCATATCATGAAGTATTTGGGAAATTACAAAGTGAAATAGCAGCCGGTACAACCTTAGTTGGAAGTACAGTTCCTACCCAAACAGTTACCACTATACAAAATGGAACTCCAATTGTACAACaagttcaattaaataaattcgatattaaatcaAGTGATGGTGAAGCTACACCAGGACCAAGCGCTTCGCCTGTATCAGTTGGGAGTCATGCATGTGAAAtatgtggaaaaatttttcaatttcgctATCAACTTATTGTTCATCGTCGATACCATACAGAAAGAAAACCTTTTACTTGTCaggtGTGTGGAAAGGCctttttaaatgcaaatgaCTTAACCCGACATGGAAAGTGTCATTTAGGTGGATCTATGTTTACTTGTACAGTTTGTTTTCATGTATTTGCAAATGCACCATCTTTAGAACGTCACATGAAACGACATGCTACCGATAAACCGTATAATTGTACCGTATGTGGAAAAAGTTTTGCAAGAAAAGAACATTTAGATAATCATACACGTTGTCATACTGGAGAAACACCTTAcagatgcCAATATTGTTCAAAAACATTTACTAGAAAAGAACATATGGTAAATCATGTTCGTAAACATACGGGTGAAACTCCTCATCGATgtgatatttgtaaaaagagtTTTACTCGCAAAGAACATTTTATGAATCATGTTATGTGGCATACGGGCGAAACTCCTCATCATTGTCAAGCTTGTGGCAAGAAATATACACGTAAAGAACATCTCGCAAATCATATGCGTTCACATACCAATGATACACCATTTCGCTGTGAAATATGCgGTAAGTCGTTTACGAGAAAGGAGCACTTCACGAACCACATAATGTGGCATACGGGTGAGACGCCGCACCGCTGTGATTTCTGCTCGAAGACATTCACACGAAAGGAGCATCTTTTGAACCACGTTCGCCAGCACACGGGTGAGTCTCCACACCGATGCGGCTTCTGCTCCAAATCGTTCACCAGAAAGGAACACCTTGTTAACCACATCCGCCAACACACAGGAGAGACGCCCTTCCGCTGTCAGTACTGTCCGAAAGCATTTACGCGGAAGGATCATCTGGTGAACCATGTCAGGCAACACACGGGTGAGTCACCGCACAAGTGCCAGTATTGCACCAAATCCTTCACGAGGAAGGAACATTTGACAAATCACGTGCGTCAACACACAGGCGAATCGCCACATCGATGCCACTTCTGCTCCAAGTCATTTACTCGTAAGGAGCATTTGACGAATCATGTGCGAATCCATACTGGTGAATCACCGCATAGGTGTGAATTCTGTCAGAGAACGTTCACCAGGAAAGAACATCTAAATAATCATCTCCGTCAACATACTGGAGATTCATCGCACTGTTGCAATGTATGCTCGAAACCATTTACAAGAAAGgaACATCTCGTAAATCATATGCGATGTCATACTGGTGAACGTCCGTTTGTATGCACAGAATGTGGTAAAAGTTTCCCCTTAAAGGGTAATTTACTTTTCCATATGCGTTCGCACAATAAAGGCAGTAATGCCGAGAGGCCGTTTCGTTGCGATCTTTGCCCAAAAGACTTTATGTGCAAAGGGCATTTAGTATCTCACAGACGATCGCATTCGGATGAACGACCTCATAGTTGTCCAGATTGCGGAAAAACATTTGTTGAAAAGGGCAATATGCTCAGACATTTGAGGAAACACGCGGCAGAAGGACCACCAACTCAAGTTAGTACTCCTTCTGCAATTCCTCAGTCCGGTGTTTTGCCGATTCCGGCAGCAGCAGTTCTTGTCGGCCATCCTTTGGCGCCTCCTGCACCACCTGTAGTGCCACAACACACTGTAGTTGTGCCTACTCCACCAGGTGTATTGACCTCCTATTAA
Protein Sequence: MALTSNSHHQSTPTHHHHQSSVSSSSHHSSLQPNPQQIPVSLPGLNLDGAHIPASVSHLQAAHAQMQQQMQAAQQQQLHQQQQPQQQQQQQQQQQSHHQIQNHQNAQNSGPTAHNQNAQRDDNKVKDEGGSCTTERCSDNQVHCQVQCDLQLQTSQDLQQSLMQQQQQQQQIGVNISGNSSSESGSQNNTEKPEKEKELRQLNMTQFQVPDLKPGGHMMDVRTADGSVVKISAGNEQDLAKTLGVEMVQNMYKVNVEDINQLLAYHEVFGKLQSEIAAGTTLVGSTVPTQTVTTIQNGTPIVQQVQLNKFDIKSSDGEATPGPSASPVSVGSHACEICGKIFQFRYQLIVHRRYHTERKPFTCQVCGKAFLNANDLTRHGKCHLGGSMFTCTVCFHVFANAPSLERHMKRHATDKPYNCTVCGKSFARKEHLDNHTRCHTGETPYRCQYCSKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQACGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCGFCSKSFTRKEHLVNHIRQHTGETPFRCQYCPKAFTRKDHLVNHVRQHTGESPHKCQYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCQRTFTRKEHLNNHLRQHTGDSSHCCNVCSKPFTRKEHLVNHMRCHTGERPFVCTECGKSFPLKGNLLFHMRSHNKGSNAERPFRCDLCPKDFMCKGHLVSHRRSHSDERPHSCPDCGKTFVEKGNMLRHLRKHAAEGPPTQVSTPSAIPQSGVLPIPAAAVLVGHPLAPPAPPVVPQHTVVVPTPPGVLTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00899003;
90% Identity: iTF_00625640;
80% Identity: -