Basic Information

Insect: Apis cerana
Gene Symbol: gtf3a
Assembly: GCA_029169275.1
Location: CM054910.1:11894954-11899311[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00013 0.015 16.3 0.1 2 23 738 759 737 759 0.97

2 16 0.94 1.1e+02 4.2 1.5 3 23 793 813 792 813 0.97

3 16 0.00028 0.031 15.3 1.2 3 23 822 843 821 843 0.98

4 16 0.0028 0.32 12.1 2.0 1 23 850 873 850 873 0.95

5 16 9.9e-05 0.011 16.7 0.7 1 23 879 902 879 902 0.94

6 16 1.4 1.5e+02 3.7 2.5 2 23 910 930 910 930 0.94

7 16 1.5e-07 1.6e-05 25.6 2.1 2 23 936 957 935 957 0.97

8 16 2.3e-06 0.00026 21.8 0.2 1 23 963 985 963 985 0.99

9 16 0.00058 0.066 14.3 2.4 2 23 997 1019 996 1019 0.95

10 16 0.0083 0.93 10.7 2.5 1 23 1025 1048 1025 1048 0.96

11 16 0.026 3 9.1 3.8 3 23 1071 1092 1070 1092 0.95

12 16 0.0012 0.14 13.3 1.4 2 23 1099 1121 1098 1121 0.96

13 16 4e-05 0.0045 17.9 1.0 2 23 1129 1150 1128 1150 0.96

14 16 0.0013 0.14 13.2 2.3 1 23 1156 1179 1156 1179 0.96

15 16 0.34 39 5.6 3.2 2 23 1186 1207 1185 1207 0.96

16 16 0.01 1.1 10.4 2.6 1 23 1213 1235 1213 1235 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00013	0.015	16.3	0.1	2	23	738	759	737	759	0.97
2	16	0.94	1.1e+02	4.2	1.5	3	23	793	813	792	813	0.97
3	16	0.00028	0.031	15.3	1.2	3	23	822	843	821	843	0.98
4	16	0.0028	0.32	12.1	2.0	1	23	850	873	850	873	0.95
5	16	9.9e-05	0.011	16.7	0.7	1	23	879	902	879	902	0.94
6	16	1.4	1.5e+02	3.7	2.5	2	23	910	930	910	930	0.94
7	16	1.5e-07	1.6e-05	25.6	2.1	2	23	936	957	935	957	0.97
8	16	2.3e-06	0.00026	21.8	0.2	1	23	963	985	963	985	0.99
9	16	0.00058	0.066	14.3	2.4	2	23	997	1019	996	1019	0.95
10	16	0.0083	0.93	10.7	2.5	1	23	1025	1048	1025	1048	0.96
11	16	0.026	3	9.1	3.8	3	23	1071	1092	1070	1092	0.95
12	16	0.0012	0.14	13.3	1.4	2	23	1099	1121	1098	1121	0.96
13	16	4e-05	0.0045	17.9	1.0	2	23	1129	1150	1128	1150	0.96
14	16	0.0013	0.14	13.2	2.3	1	23	1156	1179	1156	1179	0.96
15	16	0.34	39	5.6	3.2	2	23	1186	1207	1185	1207	0.96
16	16	0.01	1.1	10.4	2.6	1	23	1213	1235	1213	1235	0.98

Sequence Information

Coding Sequence: ATGCAGCACactgaaattaaaaacaagGATCATAATTATAGTGAAGTGAAATTGCATAACCTTCAACATACTGGTACTAATATTCAAAATGCGTACGACAATGATATTAGAACAACATATAAATCAAACAAATCTGGTATAATATCAAACAAAGAAGTATTTGgtcagattaaaaatattaatgaattaaagagAATAACACCacgtgtaaaattattaactcatGATGCAAAtagtttaaatgaattaaccaaaatttctttgcacaataaaatatctgcacaaaagaaattatcaatattggaACAAACAAAACaggaattaagaaaatattgtagaaCTTGTGCTGGTTTAAAACTTCCATTAGTTGATATTTTTAGTGAAAAAGGTAATCAAATGAGATTAAGTcaacaaataaaacatttgGAAGAAATAAATCCATATGATAGTTTATCAACTCAAATGTGTATGGATTGTATTTGTGACTTAAAAAtgagttataaattttttatgcaaattaagaAAGCAGAagtcaaattaaaatctattcatATTACTCTGACTGATACAgcaacaaaaaatatagaattaaataaaattcaatctgtaggaaattttgaaaaacaaacGGAGAACATTGTTGAGAGTATTGCAACAAATCCATCTAcaagtaaagaaaataatgaacatGCTTCTGTACCAAAAATATCTGCaatcttttcattaaaaaaaaatgaacaagaaCTTTCAAAAACTGGAAAagtaaatcttgaaaaattagaaaataaagctgaactcgaaatttttgaagattcaACTATTCTACAAAACAGTGATGATAATGAATCTATAGAAGAGTTTGATCCGGATGATCCTCCTTTTCAACCTGATAGTTCTGATGTTGCAGATTCTGATGATGAAGTAGTAATACCGAATGCAAAAAGGCGACATTTTCAACAGAAAGAAAACATCAAACAAAGTTCACagtcaatttttgtttctgataataattcagtatcagataataaaaatattgattgtaaTCAAAcaacatataattatgatacacgtctaaaaacatatattaaaatagaagataCAGAGAGTAATAATCAGTCTATTGAATCACATAGCATCATTAATTctgaaactatatataatactgaAAGTACAAAAGAATGTTCAAAACAACCAAACATATTAAAACGCagattattattgcaaaataaaaagggATCCATAGAAGAAactgatgaaaatatttgtcagtccaatatttctgataaaacTGGAAgtcataaagatttaaaagtacaaaaactagatgttaataattctttaaacatTAACAGCAATCAAGAAGATGGGATTATGTATGTTACTGTGAAAGGATCAAAaccaaatgaaatattgttagtgaaagttaaaaaaatggataaaccattagagaaaaaagatgataaatctacattaaagaaaaattttgacattaaaccaatggaaaaaattttaaaacgatatgAAACATTagttacaaaagaaaaagatttattttcagaacgaacaaaaaaatcagaaataagAGAACAAATTATAGAAGAGcaaatagaagaatataagaaaaaacgagaaaaagtaTTAGGTGGACATGCTAATATTTCGCATCCTTTAAAACTTGAAGAATCTCAAACTCGTTATTTTAAGCGTAATGAAAGGCAAGATAATCAAAGTTCTTTTACACATATAGAAAATGATACTGTTATAGACATACAGTTTAATAAAgatgataatgaatttaatgaaaatgttaaaattgaagatgATACTTCAGAAATTATAGAATCAGTCAAGGAAAAATCTACTAATGAAAATGCTTATGTAAATACTGAAGAGTATTTATCGCGTTTAGCAAAACTTAAGTTGAAATGGGAagaagcaaaaaagaaaaaagaatctcttCAAAAAGAATTAGACGAATCATATACAGaaggaaatattgaaaaattaacaagaattttaggtgaaaaagaaaaaaacttacaagattttcaagattatttaaaacaaagtaaaattgtaattacaagattaaaagatgaggatattatttctctttatgaagatagaaataacgcagtgcttaaaaataatttacctgATTTGATAGATGAAAGTCAACCGGCAGATTATATTCCAGAGGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCTTCAAAAGAAGTTCTTGAAGAACATTTGAAAATGCATGACTATAAAATTATGCATTTTTGTGAAGATTGTATGGAAGAATTTCCAACAAATAAAGCAAAACGCAATCATAatgtaatttgtataaaaaaattattatgtaaatattgtgACATGATGTTAGattcaaaaggaaaaaaacgtCAGCATGAACAAAAACATTGTGACAGTATGTATGGACAATTATGTGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACATTAGATCAACATGTAAAAACACAGCACATGAGttgggaaaaaatatatcaatgtcCAAAATGTCCTAAAAAGTTTGCATTCAAACAAAAACTCagttttcatttgaaatctGTACACACAACATTAAGAGCCTATTTGTGTGAAGACTGTGGAgctgattttaaaaatcctgCAAGTCTTAGACACCATAGAATACGTAAACATCAACCTGTAGGTAATAAAAGAGAATGCCCTGTTTGTCATAAATTAGTACCATTTTATAGTCTTTCAAAGCATATGCATACTCATAAAGCATATACTATCCAGTGTCCACACTgtgataaaatgtttaaaaatagttcAACTTTAAAACAACATGTAAGAATTCATGAAGATCAACGCCAATATCGATGCGATACTTGTGGTGTTGGATTTAATAGACGAGATGGTTTAAGATTACACATGAGAGTGCATGAGAAAACTGATAGTAGAGGATTAAAAGAATGTTCATGTCAAGTATGTggtgaaaaatttccaaatcattCAACACTTGTTATACATAGAAATCGAGTTCATAAGGATGGTAGACAATATACATGTCATATATGTAATAGATCGATGATTTCAACTAGATCATTAGAATGGCATATGTCTCATATACATAATGAATTACTTCCTGGTGTTGTAAAGGAAGATATAGATGGACCaccagaaaagaaaagggcGTCATGTTATCATTGtaacaaaacatttaaaacaGAAATGATTTTGAGgacacatattaaaaatacacataTGGAAAAAGATCCTATGAAATGTTTAGATTGTGAACTAACATTTACATCTGAAGTAAGATTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTTTGCCATGTCCACATTGTCCGAAGAGATTTGTAAATCAACTCAGATTAAAAACTCATATGATATCCCATTCTGAAGAAAGACCATACACTTGTGAAATTTgtggatttaatttaaagactAAAATACAGTTGATTAAGCATCATCAAAATAGACATAGTGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCTCTTGTATGTCATGAGAGAACTCATACAAATGAACGACCATATTCTTGTAGTGTGTGTAGAcaacgttttaaatatttaggtgataaaaataaacatgaaaGGCGACATGAAAGTTTAGGAGGATCTGGATTTAAAAGAATAGTACTTGGTCGAAATATTAAAGCTAAAGTACAAGAAGATTCTTCTTGTTCTGAGCATGAACAAGAAGTCTTAGCTAGTACAGAGCCTCAAGTTCctgaaaatgaatatcaagAACAAACAGATCAACAATTTGAGGAGGAACAAATAGTTAAATTCGAAGAAGAACAAATAgttaaatttgaagaagaacAGATAGTTAAATTTGAAGAACAAGAAATAGCAGAGGAATACGAACAAGTATATGAAcagGAATATGAAGAAACATCTAGAGAAGCTTCGGATGCAGCAGAAGTTATAATGAATATGGAAGATACAACTGTTTATACTGAAGAAGTAACTGCAGATAATATTGAACCTGCAGAAATTATGGCAGATGAAATGAtgacaaatgaaatattacaatcaGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGAAAAATACAAGTGATCCCAGTGATGTTATCTTTACCTGATTTAACTGATGCAAATACAGAAGTCAATTTAGCTACTGCatctattatgtataataattga
Protein Sequence: MQHTEIKNKDHNYSEVKLHNLQHTGTNIQNAYDNDIRTTYKSNKSGIISNKEVFGQIKNINELKRITPRVKLLTHDANSLNELTKISLHNKISAQKKLSILEQTKQELRKYCRTCAGLKLPLVDIFSEKGNQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLKSIHITLTDTATKNIELNKIQSVGNFEKQTENIVESIATNPSTSKENNEHASVPKISAIFSLKKNEQELSKTGKVNLEKLENKAELEIFEDSTILQNSDDNESIEEFDPDDPPFQPDSSDVADSDDEVVIPNAKRRHFQQKENIKQSSQSIFVSDNNSVSDNKNIDCNQTTYNYDTRLKTYIKIEDTESNNQSIESHSIINSETIYNTESTKECSKQPNILKRRLLLQNKKGSIEETDENICQSNISDKTGSHKDLKVQKLDVNNSLNINSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKDDKSTLKKNFDIKPMEKILKRYETLVTKEKDLFSERTKKSEIREQIIEEQIEEYKKKREKVLGGHANISHPLKLEESQTRYFKRNERQDNQSSFTHIENDTVIDIQFNKDDNEFNENVKIEDDTSEIIESVKEKSTNENAYVNTEEYLSRLAKLKLKWEEAKKKKESLQKELDESYTEGNIEKLTRILGEKEKNLQDFQDYLKQSKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKEVLEEHLKMHDYKIMHFCEDCMEEFPTNKAKRNHNVICIKKLLCKYCDMMLDSKGKKRQHEQKHCDSMYGQLCDVCGEKFKHQGTLDQHVKTQHMSWEKIYQCPKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVGNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNELLPGVVKEDIDGPPEKKRASCYHCNKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFTSEVRLRHHMMVTHNRLEGTLPCPHCPKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIVLGRNIKAKVQEDSSCSEHEQEVLASTEPQVPENEYQEQTDQQFEEEQIVKFEEEQIVKFEEEQIVKFEEQEIAEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPAEIMADEMMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLTDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00734092;
80% Identity: -