Basic Information

Insect: Apis cerana
Gene Symbol: mecom-b
Assembly: GCA_029169275.1
Location: CM054903.1:7661257-7667246[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0036 0.41 11.8 0.7 2 23 61 83 60 83 0.96

2 9 0.13 15 6.9 0.1 1 23 90 113 90 113 0.93

3 9 1.4e-05 0.0016 19.4 1.6 1 23 119 146 119 147 0.93

4 9 4.1e-06 0.00046 21.1 2.6 1 23 153 175 153 175 0.95

5 9 2.5e-05 0.0028 18.6 5.0 1 23 181 203 181 203 0.99

6 9 0.0005 0.056 14.5 0.7 2 21 211 230 210 231 0.95

7 9 5.9e-09 6.6e-07 30.0 1.2 1 23 598 620 598 620 0.99

8 9 3.1e-07 3.5e-05 24.6 1.7 1 23 626 649 626 649 0.97

9 9 8.7e-06 0.00098 20.0 3.4 1 23 655 677 655 677 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0036	0.41	11.8	0.7	2	23	61	83	60	83	0.96
2	9	0.13	15	6.9	0.1	1	23	90	113	90	113	0.93
3	9	1.4e-05	0.0016	19.4	1.6	1	23	119	146	119	147	0.93
4	9	4.1e-06	0.00046	21.1	2.6	1	23	153	175	153	175	0.95
5	9	2.5e-05	0.0028	18.6	5.0	1	23	181	203	181	203	0.99
6	9	0.0005	0.056	14.5	0.7	2	21	211	230	210	231	0.95
7	9	5.9e-09	6.6e-07	30.0	1.2	1	23	598	620	598	620	0.99
8	9	3.1e-07	3.5e-05	24.6	1.7	1	23	626	649	626	649	0.97
9	9	8.7e-06	0.00098	20.0	3.4	1	23	655	677	655	677	0.99

Sequence Information

Coding Sequence: ATGGAGGAACGATTAACGTTCTATGGGGGGGTTGGTTGCGTGGCGAGGGGCGTAGTTGGTGGCGTAGGGGCTGTGCCCGGTTCCCATGAAGGTCCGTTGGGGGCCATCGCTCGACCATATGCCTCGCAACACAGTGGAACCGTAGACGAGGACaaggaggacgaggaggagggcgAGACTAGATGCACCGTCTGCGACAAACCGTTTCAAGATATCGAATTATTGGACAGCCATCTGATAACCTGTCACAGATACCCGGCGGAGCAGCATCGGTGCGACAATTGTCCCAGAGCGTACGCCTGGCGGCCTTTGTTGGTACGTCACCGAGCGATCGTTCACGGCGACCTTCGAAACTACCCTTGCGAGAACTGTCCGAAGTCGGACAAACCGCAGGTCTTCACGGACCCGTCCAATCTTCAGCGCCACATCCGAACCCATCACGTGGGCGCGAGGAGCCACGCGTGCACCGAGTGCGGCAAGACGTTCGCGACCAGCTCCGGGCTGAAGCAGCACACCCACATTCACAGCAGCGTGAAACCGTTCCAGTGCGAGGTCTGCTTCAAGGCGTACACCCAGTTCTCCAATCTATGCCGGCACAAACGCATGCACGCCGATTGCCGTATGCAGATCAAGTGCGTGAAATGCGGCCAGTCGTTCAGCACGGTCACCTCCTTGTCCAAGCATAAGCGATTCTGCGACTCGACGCCGCCTACCGGCCCACCAGGCGCCATGCCGCAATTGCCCACCCCGACCCCCAGCCCTTTCCTCGTTTACCCCAGACCCCCGGTCAGCCTCCCCGGAGGTTTGCCCTTCTATCCGACCAGCCTGATGGGCCCTTATCCAGGAATCTTCCCCAATGCCCCCAATTTCTTGAACACCCCCCTCCTGTTCCCGCCGAAGGTCGAGGAGGCCGAGAAGAGGAGCGAGAGCCCGAAGAAGGAACGTTTCACCCCGCCAAGGGTCCTGCCGCAGCACAGCAAAGTGTCGCCGTCCACCGCCGAGGAGGCGACCTCCTCGTTCAGACCGTCTCCGGCCAGACCGCCTATCCAGCCGACCCCGGAAAGCGACGACGACCCGTCCAAGAAACGGGAGATCGGAAGAGCGGGCAACGAGAAGAAGCCAGATCCCGAGCATACCGCGTCGACGACCACCGCGTCGTCGACGAGCGTCGAGGAGACGACGGATCAGCCGTTGGATCTGAGAGTGCAGACGAAGAAGCAAAGGACGAGTTCCTCGAACGCGACGGCCGAGAGGAAGGCGAGTCGCAGCCCGTCGCCGACCCCGGCTCGGATCGAGGAGGTCCCGCCGCCGCCCGACCCCCCCAAgccggaggaggagggggccgCCTCCGTGCCGATGGAGGTCGATTCCAAGGACGTGGCAAGCAGCCCCCAGCTGAGGACCAGTCTGCCCACCGAGCAGCCGCCCACCAACACCCCGCCGCACATGGCGTACCCCAGACCGATCCACCCCATGTTTCTCGAGGCGATGTACCGCGGCCCGACCGGCTCCTTCCCCGGGTTCCCAGGCGGGCCCCCGCCCCCGGGTGGCGCCGCGCCCGAGTCCAGGCTGCTGCCGCCCCTGCCGCCCTTCGGACCACCGCGCGGACTTCCTTTTTTAGGGACGCTTATGAACGGGCTCAGCGGCGCTAGGCCTGGAGGCGGAGGATTCGACCTGCTCGCCAGGCCGCCGCTGGGGCCGTTCCCCGGCGTGAAACCGTTTCAGGAGGCGGTGATCGCGcctcaccaccaccaccaccaccaccacgccCACGGTAAAATGAAGGATCGGTACTCGTGCAAGTTTTGCGGCAAGGTGTTCCCCAGGTCCGCGAACTTGACCAGACACCTGCGCACCCACACCGGCGAGCAACCGTACAAGTGCAAGTACTGCGAACGATCGTTCAGCATCTCGAGCAACTTGCAACGGCACGTGAGAAACATTCACGACAAGCAGAGGCCGTTCAAGTGTCCGCTGTGCGAGAGATGTTTCGGCCAGCAGACGAACTTGGACCGGCACCTGAAGAAGCACGAGGCCGACGACGGCAGCGGGGTCGTTTCCGTGGCCGACTCGCCTGGGAGCAGCAACGAGAACGAGCGCGAGGACACTTACTTCGACGAGATCAGGTCGTTCATGGGCAAAGTGACTTACGGGGGTGAAGCTGGTTACGGATTGCCGCCCCATCCGGCCTATCTGCCCAGCCGGCTTCACGAGATGCACGAGTCCAAGATGGAGACCGAGtacgacgaggacgaggacagCGAGGAAGGCGTGTCCCCCCTGGACGAGACGGATGGCATGTCCCCGGCCGAGACCAAGGAGTCGACAACCCCGCCGCCCCAGTACGACCTGAAGCTGAGGGAGAAGCAGGAACTGCTCAACAACAACACGGCCGAACCCGTGATCGAGATCTCCACATAG
Protein Sequence: MEERLTFYGGVGCVARGVVGGVGAVPGSHEGPLGAIARPYASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLITCHRYPAEQHRCDNCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTPTPSPFLVYPRPPVSLPGGLPFYPTSLMGPYPGIFPNAPNFLNTPLLFPPKVEEAEKRSESPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPIQPTPESDDDPSKKREIGRAGNEKKPDPEHTASTTTASSTSVEETTDQPLDLRVQTKKQRTSSSNATAERKASRSPSPTPARIEEVPPPPDPPKPEEEGAASVPMEVDSKDVASSPQLRTSLPTEQPPTNTPPHMAYPRPIHPMFLEAMYRGPTGSFPGFPGGPPPPGGAAPESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGMSPAETKESTTPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00024776;
90% Identity: iTF_00118172;
80% Identity: -