Aaln079148.1
Basic Information
- Insect
- Aphrophora alni
- Gene Symbol
- egg
- Assembly
- GCA_963513935.1
- Location
- OY740776.1:305080-401560[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.3e-10 1.2e-06 30.3 0.1 4 70 345 404 343 410 0.89
Sequence Information
- Coding Sequence
- ATGATATCATTAAAATTTCCAAGGCTAGACAAAGCACGTATGTTATCCTTCATTTCACACCTGATGGTGGCACATGTCCTTACCATGGCGAGTGAAAAGATATCCGGCGGTTTGCCTAGAGATACTTATCGTGTACGAATGGAGTCACCAGCACAACGGAAGGCTATACCTATTAAGAATGTAGTAGGACGGTACTTGGCTTATACAGAAATGTCACCAGTTCGTCTGCCAGTTGGTACACGAGTCATAGCCATATTTAAGGAAGAAGGTCAGCcaattaataaagaaaactattaTTCTGGAATTGTTGCAGAACCACCAAAGTCAATGAATAAATACAGgTACTTGAtattttttgatgatggatatgCTCAGTATGTAGCACACGAAAATGTTCGTTTAGTTTGTGAATGTTCAAAAAATGTTTGGGAAGATATACATCCAGAACCGAGAGATTTTATCCGAAATTATCTTCAGCAATTTCCAGAACGTCCTATGGTTAAGCTACAACGAGGCCAGATTGTTAAAACAGAATGGAATGGACGCTGGTGGATAGTGCGAGTCCTTGAAGTAGATGGATCCTTAGTCAAAGTTCACTTTGATGCAGATTCTAGAACAGAATGGATCTATCGAGGTTCAACAAGACTTGGACCTCTTTATCAAGAGATAGCTGCTGCTAGAGATAGGCAACAAAGTGGCACTCTTGCTCGAAGTCGAGGATTTGGTGCTGCTAAACAGAATAATTTACCTTATGTAGAATACACACGGACAGATGATGACAAGAAAGATGATGACAATCCTGAATTAGTTCCAACCCGATCTGTCGCCAAGAAGAGTACTGCAAGGAAATCAGAAGACAAATGTATTATATCAAATGCATTTGTACCTAAACCCTTAGTATCGCAGATACCTGTAGGCATGGTTGAAgtAAAGTTATTGGTAAATCCTTTGGAGCCAATAAAGTTCCACTCTCACGAATGTACCAAATATTGCGTATTGTGGACAGATTATAATCCTAACGAGTGTAAGGTTAAAAATCCACTCGCCATTCCTTTGATGCATGCATTCCAGAGGTTGATCTATCGTTTCCGTAATAAACGTGTAGTTATGTATGTTACACCATGTGGTCGAAGAGTTCGTTGCTACCCTGAACTTCATCATTATCTTAGACAGACGGAGTGTTTACTAACAGTTGACTTCTTTGATTTTGACTTTTGGATCAGCTGCACTACCGAGTTTCATTTGGACCGTACCTTTACACATATAGAGgATCTATCTTACGGCAAAGAAAACATTCCTATATCTTGTGTGAATGACCTTGATCACAACATGCCTCCATATGTTCAATATATGACGGAAAGACAACCGTCTGAAGGAGTACATCTTAATCTGGATAAGAACTTTCTTGTCGGCTGTGACTGCACAGATGATTGTCAgAATCAAGAGACTTGTTCTTGCTGGCAGCTAACATACGCTGGAgcaaagttttgtaattttggcCAACCTACTGATCCATTTGGTTACCAGTACAGACGACTGCCAGAGAGGGTTATTACTGGAATCTATGAGTGCAACCCTCAATGTAAGTGTGCTTCAACATGTTTAAATCGAGTGGCACAACAACCTCTCACAACCAGTTTGCAGTTGTTCAAAACAGCAAAGAAGGGTTGGGGTATCAGGACATTGTGTGATATCCCTCGAGGCGCTTTTATTTGTATCTACGCCGGATTTCTGTTAACTGAGCAAGCTGCTAATGAGgGAGGAAAGAATTATGGTGATGAATACTTGGCTGAATTGGATTATATTGAAGTTGTGGAAAGATTAAAAGAAGATTATGAAAGTGATGTACCTCGAGAACTGTTAGAAGATTCTGATGAAAACAGTGGAAATTCATTGAGTGATAATGACATTAGAGAAGAAGATATAGTCGGTGATATTGACTCCCAAGATAGTTTGAAGAAAACTGATTCAGATGAAGAATTTATAACCCATTGGAGAGACGAGAAGGGTATGAATGCTGAAAGTATAAGAACTCGCTTGCGGGCGCGAAATTCACGTTTTAATTCCACTGATGATACTGataatgaaaaagaagaaaaagcaATATTTGGAACAAATTGTGGAGACTGCGGACTACTCTTTCCAAATGTCAAAGATCGTATTAAATGCTCAGGATCTTGTGAAAAAACTTTCCATACTGGTTGTTGTTCAGTAAGAACGTTAGAAAGATTGAGTAAATTGGGCTCAAAAAGGAGTTCGTGGATGTGTTTAGAATGCAAATTGGAAGTGCAAGCTCAAAGAAAACCTTCTCATTTCAATGCGAATGTACTGGACCAAGAAGAGTATGTATCCAAGTATCCTTCAGTCCGAGACATGTATGGTGAAGACGAGTCAGTATATATAATGGATGCAAAAACCAATGGGAATATTGGTCgttatttaaatCATTCTTGTAATCCAAATGTATTTGTGCAGAATGTTTTTGTGGATACACACGACTTACGTTTTCCATGGGTTGCTTTTTTCTCTCTGAATTTCATAAATGCTGGATCAGAACTAACTTGGGATTATAATTATGATGTAGGCAGTGTTCCAGGAAAGGTTTTACACTGTTATTGTGGTTCAAATAACTGTAGAGGCCGActgttgtaa
- Protein Sequence
- MISLKFPRLDKARMLSFISHLMVAHVLTMASEKISGGLPRDTYRVRMESPAQRKAIPIKNVVGRYLAYTEMSPVRLPVGTRVIAIFKEEGQPINKENYYSGIVAEPPKSMNKYRYLIFFDDGYAQYVAHENVRLVCECSKNVWEDIHPEPRDFIRNYLQQFPERPMVKLQRGQIVKTEWNGRWWIVRVLEVDGSLVKVHFDADSRTEWIYRGSTRLGPLYQEIAAARDRQQSGTLARSRGFGAAKQNNLPYVEYTRTDDDKKDDDNPELVPTRSVAKKSTARKSEDKCIISNAFVPKPLVSQIPVGMVEVKLLVNPLEPIKFHSHECTKYCVLWTDYNPNECKVKNPLAIPLMHAFQRLIYRFRNKRVVMYVTPCGRRVRCYPELHHYLRQTECLLTVDFFDFDFWISCTTEFHLDRTFTHIEDLSYGKENIPISCVNDLDHNMPPYVQYMTERQPSEGVHLNLDKNFLVGCDCTDDCQNQETCSCWQLTYAGAKFCNFGQPTDPFGYQYRRLPERVITGIYECNPQCKCASTCLNRVAQQPLTTSLQLFKTAKKGWGIRTLCDIPRGAFICIYAGFLLTEQAANEGGKNYGDEYLAELDYIEVVERLKEDYESDVPRELLEDSDENSGNSLSDNDIREEDIVGDIDSQDSLKKTDSDEEFITHWRDEKGMNAESIRTRLRARNSRFNSTDDTDNEKEEKAIFGTNCGDCGLLFPNVKDRIKCSGSCEKTFHTGCCSVRTLERLSKLGSKRSSWMCLECKLEVQAQRKPSHFNANVLDQEEYVSKYPSVRDMYGEDESVYIMDAKTNGNIGRYLNHSCNPNVFVQNVFVDTHDLRFPWVAFFSLNFINAGSELTWDYNYDVGSVPGKVLHCYCGSNNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -