Basic Information

Insect: Aphodius sticticus
Gene Symbol: Hr39
Assembly: GCA_963966075.1
Location: OZ014513.1:26204382-26214949[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.35 8.6e+03 -2.8 2.3 114 152 133 173 2 195 0.50

2 5 2 5e+04 -8.5 12.1 55 164 148 233 111 290 0.36

3 5 0.13 3.2e+03 -1.4 5.0 52 156 226 334 212 350 0.51

4 5 1.5e-08 0.00036 21.5 0.0 1 28 416 443 416 542 0.74

5 5 5.6e-72 1.4e-67 230.4 0.1 206 408 549 746 540 746 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.35	8.6e+03	-2.8	2.3	114	152	133	173	2	195	0.50
2	5	2	5e+04	-8.5	12.1	55	164	148	233	111	290	0.36
3	5	0.13	3.2e+03	-1.4	5.0	52	156	226	334	212	350	0.51
4	5	1.5e-08	0.00036	21.5	0.0	1	28	416	443	416	542	0.74
5	5	5.6e-72	1.4e-67	230.4	0.1	206	408	549	746	540	746	0.98

Sequence Information

Coding Sequence: ATGGCAGCAGAAATGAGGTCCCCGAACGTATCAGTGACCCCCATCAACATGGAACCATACTCACCCCCGACCCTTAACGGAACCTCCATCAACGGTGACCATATACATCACCTGCAGGAGAGGAGATCCCATCAGCAGAGCGTGGTCCTGACCACGTCATCCGCGGGGGCCACAGGGGCGGAACCCCTTGACCCATCCGATGCTGAGGTTGCCGAGATCGACTTTCAGATGAACGTCAACATGCGCACCAAGAAGACGAGGCCCATCGAGGACCTAGCGCCACGACCCATGTCATGGGAGGGCGAACTGTCAGATGGGGAAAGGGATCACATGTGCATTGATGATGGCCATAGAACGCAGCTTCCAGAAAACCTCTCCGTCGTCCAAAACAAGCAACCACAGACAAATGACGACTCCAAGGAGAGTCCAATACTGAGACTGAAGCACACCGTATCAACTTCAACGCAGCACGTCAGCAGCTATTCTCTTCATAGTACACCGAGCAATTCTCCATTATTAAGCCAGAGGCAGTATTCTACAACGTTGACGGGCGGTAGTGGTCTACCGTCTTCGATGATTGGCCATAAAGATCTCATGCATAAAGCGCTGAACGTCCCGCCTACTCCAAGTCCAGATTCGGCCATACATTCGGCGTATAGCGTCTTCAGTTCGCCGAATCAGAGTCCTTTGACGCAGAGGCACGTCACGCTGACGCCGAATCTCAGCAGGAACAACAGCGATGCATCACATTCAAGCTGTTACAGCTGTTCCAGTGTTTCTGTGTCCGTTTCGCCAACACAGCAGTTCTCGCCTACACATAGTCCGATACAGGGTAGACATCATGTTCCCAACATACACAACAGTCCACTTCATCATCACGGTGTCCTATATAGGAGTGTTCAGGAGGACCAAGGCATCCACTACACGACGAATGATCACGAGGCGCTTCTGGACGAGCATGACGACAAAGCTGGGCTTATCCACGCTCCTCTGACGGCCCAAACGGGCATCTCCAGGCAGCAATTAATCAACAGTCCTTGTCCGATATGCGGTGACAAAATATCGGGTTTCCATTACGGCATCTTTAGCTGTGAATCGTGCAAAGGTTTCTTCAAAAGGACCGTGCAAAATCGAAAGAACTACGTGTGTTTGCGCGGAGCGGCATGTCCAGTAACTGTGGCCACGAGGAAGAAGTGTCCCGCGTGTCGGTTTGATAAATGTTTGAAATGCGGAATGAAACTAGAAGCTATTAGGGAGGATCGCACCAGGGGCGGTAGATCCACCTACCAGTGTTCGTACTCGCTACCTCCGTCTCTGGCCGGCCATCCGGAATTAAGGGCTAGCGCGAACGATCTCAGGCATGGCATGGGGGAGCATTCCCACCTTACTGTGAAACTGGAACCTTCGGATATTGGAATCTCTGGCCATTTGTCGAGCAAGAGGCTGAATTCCGCTCGCCATGGCGTCCCGGCATTATTGCAAgaaataatgGATGTGGAACATTTATGGCACTATAGTGAGTCCGAgctgaacaaactaaacacAGAAGGTACCCTAAGCAAGGGTGGGTCGTCTAGTGCGGTTCATAATCTCTCCACTCATCCTTTACTAGCGGGAACTGGTCTGGCTGGCTCCGCGGACACCAACCCCGATTTCGTAGCAAATTTGTGCAATATCGCCGACCATAGACTGTATAAAATTGTTAAGTGGTGTAAAAGCTTGCCTCTATTTAAGAATATATCGATTGACGACCAAATCTGCCTACTTATAAATTCCTGGTGTGAATTGTTACTATTCTCCTGTTGTTTTCGATCTATGGATAATCCTGGAGAAATCAGGATATCTTTGGGAAAGAGTTTAACGTTGCCTCAAGCGAGGGACCTCGGCATGCAGGCATGCATTGAGAGGATGCTGAATTTCACCGAACAATTGAGAAGGTTACGAGTCGATAAGTACGAGTACGTGGCTATGAAGGTTATAGTGCTGCTTACTTCagatacctcggaactaaaagaagctGAAAAGGTACGCGCATCACAGGAGAAAGCTCTAAAAGCTTTGCAAGATTACACCTTGGTTCACTATCCGGACTTGCCGGCGAAATTTGGCGAATTGCTGCTCAGAATACCCGAATTGCAGAGAACTTGCCAGGCCGGCAAGGAGCTGTTGACAATAAAAACGAAAGATGGCGAGGGTCCTAGTTTCAACTTGCTGATGGAGTTACTTCGCGGGGACCACTAG
Protein Sequence: MAAEMRSPNVSVTPINMEPYSPPTLNGTSINGDHIHHLQERRSHQQSVVLTTSSAGATGAEPLDPSDAEVAEIDFQMNVNMRTKKTRPIEDLAPRPMSWEGELSDGERDHMCIDDGHRTQLPENLSVVQNKQPQTNDDSKESPILRLKHTVSTSTQHVSSYSLHSTPSNSPLLSQRQYSTTLTGGSGLPSSMIGHKDLMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCYSCSSVSVSVSPTQQFSPTHSPIQGRHHVPNIHNSPLHHHGVLYRSVQEDQGIHYTTNDHEALLDEHDDKAGLIHAPLTAQTGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLKCGMKLEAIREDRTRGGRSTYQCSYSLPPSLAGHPELRASANDLRHGMGEHSHLTVKLEPSDIGISGHLSSKRLNSARHGVPALLQEIMDVEHLWHYSESELNKLNTEGTLSKGGSSSAVHNLSTHPLLAGTGLAGSADTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMDNPGEIRISLGKSLTLPQARDLGMQACIERMLNFTEQLRRLRVDKYEYVAMKVIVLLTSDTSELKEAEKVRASQEKALKALQDYTLVHYPDLPAKFGELLLRIPELQRTCQAGKELLTIKTKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01098567;
90% Identity: iTF_00136915;
80% Identity: iTF_00138153;