Basic Information

Insect: Aphodius granarius
Gene Symbol: Lztr1
Assembly: GCA_963971325.1
Location: OZ020226.1:20106755-20110417[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2.3e-09 7.1e-07 30.2 0.2 3 108 362 495 360 497 0.83

2 4 0.41 1.3e+02 3.6 0.1 77 109 496 528 492 529 0.88

3 4 8.5e-20 2.7e-17 63.8 0.1 5 97 585 677 581 691 0.85

4 4 1.8 5.5e+02 1.6 0.1 77 99 691 713 685 718 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2.3e-09	7.1e-07	30.2	0.2	3	108	362	495	360	497	0.83
2	4	0.41	1.3e+02	3.6	0.1	77	109	496	528	492	529	0.88
3	4	8.5e-20	2.7e-17	63.8	0.1	5	97	585	677	581	691	0.85
4	4	1.8	5.5e+02	1.6	0.1	77	99	691	713	685	718	0.83

Sequence Information

Coding Sequence: ATGAGTGGAACTGCTTGCTCCAGTTCTACCTCGCTTGGTTCAGCGTCAGTCTTCGATGGATTAACCCTAGAATTTGGTCCGTTCGAGACAGTACATCGTTGGAAACGACTACCAGGCTGCGCAGAGTTTGTTGGAGCGAGACGTAGTAAACACACAGCAGTTGCCCATAATGAGGCGATATATGTCTTCGGGGGTGACAATGGAAAGAGTATGTTAAACGACATGGTAAGGTATGACATAAAAGAAAGATCGTGGGGTCGAGCTATTGTGAACGGAACGCCTCCTGCTCCAAGATATCACCATTCTGCCGTTGTTCATAATACTTCGATGTACGTTTTTGGAGGTTATACAGGAGATATACATTCAAACTCAAACTTGACGAATAAGAATGATCTGTTTGAGTATCGTTTAGTTACCGGGGTTTGGATTGAGTGGAAGTTTACCGGTAGAATACCGGTTCCGAGATCGGCTCATGGGGCTGCAGTTTTCGACAATAAGTTGTGGATTTTTGCTGGTTATGATGGAAATGCTAGATTGAATGATATGTGGACAATTTCATTGGTTGGTGAAAATCGTGTTTGGGAGGAAATTGATCAAAAAGGAGAACGACCCCCAACCTGCTGTAATTTCCCAGTAGCCGTGGCTAGGGATTGCATGTTTGTTTTTAGTGGTCAAAGCGGAGCTAAGATCACAAATTCTCTCTTCCAGTTTCACTTCCGAACCAAAACCTGGACAAGAATCTCAACGGAACACATTCTCCGTGGGGCTCCTCCACCACCAGCTCGTCGCTACGGTCACACCATGGTAGCCTTCGACAGGCACCTATACGTTTTCGGGGGTGCTGCCGATAGCACGCTCTCCAATGACCTGCATTGCTTCGATCTGGACACCCAAACGTGGACGATTGTTTTGCCTTCTGCAGAGTCAATTGTACCGTCGGAACGGTTGTTTCACGCCGCCGCCGTCGTGGGGAATGCCATGTACATTTTCGGGGGTACAATTGACAATAACGTGAGAAGCTGCGAGATGTACAGGTTCCAGTTCTCAAGCTATCCCAAGTGTACGCTACACGATGATTTCGGAAAAATTTTGGAATCGAGACTCTTTAGCGACGTACAGTTTATTGTCGGCACCGAGGAGGTTAGGATCTTGGCTCACCTTCCCATGGTTGCTGCTAGGTCGCAGTATCTTCGGAAGCAGgtGCGACAAGCAAAAGAACTTAGGGATAAGAAACATAATGCGGCCACCACACCTCCGAATGAACTACCAATGGTCGAAGTAAGTTTGGTAGATGCAAATCCGGAGGCTTTTGAAATGGTCTTGGACTATATATACATGGACTGCATCGATCCCATAAAGAAAGCAAAGCAAGGTGAAGATCCTTTTAGCAATCGCCTTGTACTTTTGATGATGGACGTTTATCGATTGGCGGTCAAATTCAAAATGACTAGACTGGAATATCTTTGCGTGCAATATTTAAACGCGACTATTTGCCTCAAGAACGTTCTCGTGGCGCTGCACAATGCCGATCTTTTGAATTTGGACTACATCAAAGAGTTTTGTTTGAGGTTTATCGTCAAAGAGTCCAATTATAATCAGATTGTTATGAGCGATGAATTTGAAACTCTTGATCGAAAACTTATGGTGGAAGTGGTTAGAAGAAAGCAGACGCCGCAACCTAAGGCACTTAGTGAACCATTAATGGACACCACCGGATTGTCTCTGGAACAGGATATGGCACTTTTCCTGATGATGACCGGGAAAGAATTCTGCGATATTAACTTGATTGTTGATAATCATGTTGTTCCCGCGCATAAATGCATTTTAGCTGCTAGATGTGGATACTTTGAGGCTATGTTCAGGTCTTTTATGCCAGCGGATAATACTGTTAGGATACAGATAGGAGAGATGACCCCTTCAATAGAATCATTCAATTCCCTCCTCAGATACATCTACTACAGTGAAGTAAACATGCCTCCGGAAGATTCACTATACCTTTTCTCCGCCCCCCTATTCTATAATTTCACTAACAACAGACTCCAGGCGTTCTGCAAGCAAAATCTTGAGATGAATGTAACCGTGGACAACGTGATTCAACTCCTAGAAGCTGCTGATAAGATGCAGACAAGCGACATTAAATCTTATGCCATGTGTCTGATTGTGTTTAACATTACGAAGATTGCTAAGTTGGAGCGTCTGAAGACCCTGAGCAAGGAACTGATCTTGGAGATTTTGCTCGCGGTGGCCAATGACCTGTCGGAGACAAAGATCTGTCAGGATATATCGTCGATAAGTTTGAATAGTGAGTCATGA
Protein Sequence: MSGTACSSSTSLGSASVFDGLTLEFGPFETVHRWKRLPGCAEFVGARRSKHTAVAHNEAIYVFGGDNGKSMLNDMVRYDIKERSWGRAIVNGTPPAPRYHHSAVVHNTSMYVFGGYTGDIHSNSNLTNKNDLFEYRLVTGVWIEWKFTGRIPVPRSAHGAAVFDNKLWIFAGYDGNARLNDMWTISLVGENRVWEEIDQKGERPPTCCNFPVAVARDCMFVFSGQSGAKITNSLFQFHFRTKTWTRISTEHILRGAPPPPARRYGHTMVAFDRHLYVFGGAADSTLSNDLHCFDLDTQTWTIVLPSAESIVPSERLFHAAAVVGNAMYIFGGTIDNNVRSCEMYRFQFSSYPKCTLHDDFGKILESRLFSDVQFIVGTEEVRILAHLPMVAARSQYLRKQVRQAKELRDKKHNAATTPPNELPMVEVSLVDANPEAFEMVLDYIYMDCIDPIKKAKQGEDPFSNRLVLLMMDVYRLAVKFKMTRLEYLCVQYLNATICLKNVLVALHNADLLNLDYIKEFCLRFIVKESNYNQIVMSDEFETLDRKLMVEVVRRKQTPQPKALSEPLMDTTGLSLEQDMALFLMMTGKEFCDINLIVDNHVVPAHKCILAARCGYFEAMFRSFMPADNTVRIQIGEMTPSIESFNSLLRYIYYSEVNMPPEDSLYLFSAPLFYNFTNNRLQAFCKQNLEMNVTVDNVIQLLEAADKMQTSDIKSYAMCLIVFNITKIAKLERLKTLSKELILEILLAVANDLSETKICQDISSISLNSES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00981261; iTF_01098590; iTF_01097637;
90% Identity: iTF_00981261;
80% Identity: -