Basic Information

Insect: Aphodius granarius
Gene Symbol: Hr39
Assembly: GCA_963971325.1
Location: OZ020228.1:9030198-9036327[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.1 1.2e+04 -3.9 4.4 87 160 101 179 2 199 0.54

2 6 3 3.3e+04 -10.2 12.8 97 157 182 244 107 290 0.34

3 6 0.49 5.4e+03 -2.7 4.1 52 126 224 292 206 326 0.45

4 6 3.7e-08 0.0004 20.8 0.0 1 24 414 437 414 486 0.82

5 6 0.36 3.9e+03 -2.3 0.0 89 118 478 505 450 517 0.80

6 6 2.7e-72 2.9e-68 232.0 0.0 205 408 546 744 522 744 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.1	1.2e+04	-3.9	4.4	87	160	101	179	2	199	0.54
2	6	3	3.3e+04	-10.2	12.8	97	157	182	244	107	290	0.34
3	6	0.49	5.4e+03	-2.7	4.1	52	126	224	292	206	326	0.45
4	6	3.7e-08	0.0004	20.8	0.0	1	24	414	437	414	486	0.82
5	6	0.36	3.9e+03	-2.3	0.0	89	118	478	505	450	517	0.80
6	6	2.7e-72	2.9e-68	232.0	0.0	205	408	546	744	522	744	0.97

Sequence Information

Coding Sequence: ATGGCAGCAGAAATGAGGTCTCCAAATGTATCTGTAACCCCCATAAATATGGAACCGTACTCACCTCCCACTATGAATGGGACCTCCATTAATGGTGACCATTTACATCACCAGCAGGAGCGAAGATCCCATCAGCAGAACGTTGTCCTCACTACTACTTCAGCACCTGGTGGTGCTGAAACTTTGGATCCTTCGGACGCCGAGGTAGCTGAGATTGAATTTCAGATGAATGTTAATATGAGAAGCAAGAAAACTAGGGGTGGCGAAGAGATGGCTCCAAGACCCATGTCTTGGGAGGGGGAGTTATCTGATGGGGAAAGGGACCATATGTGTATCGATGAAGGGCACAGAACACAGCTTCCCGAGAACCTCTCAGTCGTCCAAACGAAACCCCAAACACCTGAAGACTCAAAAGAAAGTCCAATACTCAGATTAAAGCACCAAGTCTCGACATCAACCCATCAAGTTAGCAGCTATTCTATACATAGTACACCAAGTAATTCACCATTGTTAAGTCAACGGCAGTATTCTACGACCCTGAGTGGTGGGGGTGGTCTTCCGTCGTCCATGTTGGGACATAAGGACCTTATGCACAAAGCTCTCAATGTGCCACCGACGCCAAGTCCTGATTCTGCGATTCACTCAGCGTATAGTGTTTTCAGTTCGCCGAATCAAAGCCCTTTGACGCAAAGACATGTCACCCTGACGCCTAACCTAAGCAGAAATAATAGTGACGCGTCACACTCGAGCTGTTATAGTTGTTCAAGTGTTTCCGTTTCCGTTTCGCCGACGCAGCAGTTTTCGCCGACGCACAGTCCAATACAGGGTAGACATCATGTACCAAACATCCACAACAGTCCACTGCACCATCACGGCGTCCTGTACAGGAGCGTGCAGGAAGACCAGGGCGTCCACTATACCCAAAACGACCACGAGGGTCTTCTGGACGAGCACGACGACAAGGCTGGCCTTGTTCATGCGCCCCTCTCCGCCCAGACCGGTATCTCCAGACAACAGTTGATCAACAGTCCCTGTCCCATCTGCGGGGACAAAATCTCCGGTTTTCACTATGGTATCTTCAGTTGCGAATCCTGCAAGGGTTTCTTCAAAAGGACCGTGCAGAACCGAAAGAACTACGTGTGTTTACGGGGCGCCGCTTGTCCCGTCACCGTGGCGACGAGGAAGAAGTGCCCCGCGTGTCGATTCGACAAGTGTCTAAAATGCGGAATGAAATTGGAAGCAATCAGGGAAGACCGCACCAGGGGCGGTCGGTCCACGTACCAGTGTTCCTACTCGCTGCCACCATCTCTCGCGGGGCATCCCGAGTTGAGAGCTAGCTCAAGCGACCTAAGGCACGGTTTGGGGGAACATTCCCACTTAACTGTCAAATTGGAACCTCCTGATATCGGAATTCCCGGTCACTTGTCGAGCAAGAGGCTGAATTCTGCACGTCACGGCGTCCCGGCGTTATTGCAAGAAATAATGGATGTGGAACATTTGTGGCATTACAGTGAATCTGAGCTGAATAAACTAAATACGGAGGGTACCTTGGGTAAAGGGGGGTCTGGTAGTGCGGTACATAATCTATCCACGCATCCTTTACTCGCGGGAACTGGTTTGGCTGGCTCGGCTGATACAAATCCTGATTTTGTGGCAAACTTGTGCAATATTGCCGACCATAGACTGTACAAAATTGTCAAATGGTGTAAAAGTTTGCCTCTTTTTAAGAATATATCTatcgaCGATCAAATTTGCCTTCTTATTAACTCATGGTGTGAACTGTTGTTATTCTCGTGTTGTTTTCGGTCAATGGACAATCCGGGCGAAATTCGTATCTCGCTCGGTAAAAGCCTAACTTTACAGCAGGCTAGAGACCTCGGTATGCAGGCCTGTATAGAGCGCATGCTGAATTTTACCGAACAGTTACGAAGATTGCGCGTCGACAAATACGAATACGTGGCCATGAAGGTTATAGTGCTGCTAACTTCAGATACCTCCGAACTGAAAGAAGCTGAAAAGGTGCGGGCGTCACAAGAAAAAGCCCTGAAAGCGCTCCAAGACTACACATTGGTCCACTATCCGGATTTGCCGGCAAAATTTGGAGAATTGCTACTAAGAATACCGGAATTGCAAAGAACTTGCCAGgctGGTAAGGAGCTGCtgacaataaaaacaaaagacGGCGAGGGTCCTAGTTTCAACCTGCTGATGGAATTGTTGAGAGGGGACCATTAG
Protein Sequence: MAAEMRSPNVSVTPINMEPYSPPTMNGTSINGDHLHHQQERRSHQQNVVLTTTSAPGGAETLDPSDAEVAEIEFQMNVNMRSKKTRGGEEMAPRPMSWEGELSDGERDHMCIDEGHRTQLPENLSVVQTKPQTPEDSKESPILRLKHQVSTSTHQVSSYSIHSTPSNSPLLSQRQYSTTLSGGGGLPSSMLGHKDLMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCYSCSSVSVSVSPTQQFSPTHSPIQGRHHVPNIHNSPLHHHGVLYRSVQEDQGVHYTQNDHEGLLDEHDDKAGLVHAPLSAQTGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLKCGMKLEAIREDRTRGGRSTYQCSYSLPPSLAGHPELRASSSDLRHGLGEHSHLTVKLEPPDIGIPGHLSSKRLNSARHGVPALLQEIMDVEHLWHYSESELNKLNTEGTLGKGGSGSAVHNLSTHPLLAGTGLAGSADTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMDNPGEIRISLGKSLTLQQARDLGMQACIERMLNFTEQLRRLRVDKYEYVAMKVIVLLTSDTSELKEAEKVRASQEKALKALQDYTLVHYPDLPAKFGELLLRIPELQRTCQAGKELLTIKTKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01098567;
90% Identity: iTF_00136915;
80% Identity: iTF_00136915;