Basic Information

Insect: Aphodius granarius
Gene Symbol: BAZ2B
Assembly: GCA_963971325.1
Location: OZ020222.1:671834-701160[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 2.3e-17 1.5e-13 51.0 0.0 4 75 678 750 676 752 0.92

2 2 0.35 2.3e+03 -0.9 0.0 40 57 1409 1426 1407 1435 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	2.3e-17	1.5e-13	51.0	0.0	4	75	678	750	676	752	0.92
2	2	0.35	2.3e+03	-0.9	0.0	40	57	1409	1426	1407	1435	0.84

Sequence Information

Coding Sequence: ATGGATAAAGAAAATGGGAAGAGCAGTGACGGTGGTTCAGGCTCCAGCAAACTCTCCAATCCAACAGACCCAACAGCTCTACTCGATGCGGCCAGCCTATTCGCGTATTGGCCGCGTGGAGATGCAAATTCTGCGAACGCCGCCAGTCTGTTCGCCAGTTCTGGCGGCGCGTACGGCCTACCGCACCCGGCGATGCCGTTCGGGATGTTGCCGCCGACGCCGGGACGCGGCGTCCCGTCTTTTCCACCTGCATCGAGCGCGGCGGCGGGCTACAGTAACGCCTACACGAACACGCTGTCAGCCGCAGCCGCGAGCCAGGCGGCGAGCCTCGGCCTACCCGCAGCCAGTGCAGCCTGGTGGTCGATGGCGTCCCACCTCGCAGCTCAAGACTACCTCGCGCGGCTGCAAGCGACGGGCCTGAGCTTCCCAGGCCTGGGAAGCCCCGCAGACCCGTACGCCGCCCTCGGCCTACCGtccctcggcggcggcggccACCACAAGTCCACGAAGAACTCCAAAAGTTCCTCCACGTCGTCATCACTGCCAAAATCTCTGCAGGGCTCCTCCTCAACGAAAGACAAATCCTCAACGAAATCCTCGAACGACGCACGATCAGATATTAAGACTAGTTCGCCTATGCCCAACAGCAAGAGTTCTTCTTCCTCGACCACGCCTAAATACTCAAATTCGGGAATCGGTGGTTACGGTGGTCAAGGGATGAAGATGCCTTCGACTTCTACGAATTCGACGACAACGACCGTTAGTTCGATGGGTTCGAATGGTGAGAAGAAGTCGCAGAGGATGCTTCAGCAGCAGCAAAATAGTGGGGAGTTGAAGTATGGGGAGAGGACTAAAAGTGCTTCGTCGCCGTCGCCTAGTATCTTCACAAATCCGTTAAGTATGGCCAGTAACGATAGGGGAACGCCTACGAATTCGGCGACGTCCACGCCACCTCCCGGCACCAGTGGTAACGCCGCTGTGCCAGGTATTCCAGCCAGTATACTTAGCGATCCGAATTCCATACTAGGAGGGGTTAGGTTACCTCCGGACACCGAAATAATCAAGTATACCTCGTCCATAGTCGGCCCCAAAATACCAGGAACGACGAATAGGGGTCGAAAAAAGACTATATCCCTCGATCCACCTTCCGTAAGTCTACATCCGAGCCTGTCCAGCACCGGAATGCTCATAGAAAGCAGAAGTAGCAAAAGACAGAAGCTGGATCTTTCGGATATGGGTTCGCCTGCTAGTCCTGGCGATCGCGTGGAGGTGATTAAATTGCCTGCGACGAACGGTAGCCCGTCTGGAATCTCATCGTTGAATAGTAGCGGGAATAATCTGGATTCGTCGGCGGACGGTCCGTTGAATTTGTCGCTGAAACCGGCTACGTCGACGCCTACAAATCATCACACGAGTTCGTCGTTAAATTCGTTGAGTAATATGTCGGCGAATATCGGAATGGATAGGATATCTCGAAGAAAACCCGGTCCGAAACCAAGAAAAGTCATCCAATCACCATCGTTACCACCCAGCGCGTCCCCAAGCGCCTCCCTGGCGCAACTCTTCGCCCCCATCGACTCCTCCCGACCGCCCAGCCGAACAGACCCGATGGACGGCTCCCTAAACAACTCCACATCGCCCGGCATGTCCCTACCAGCGCCCAACCACAAAGACGGCAGACCCAGGAACCTCGGACGCGGCGTCAGCAAACCCAAGAAGAACACCGTCGCTTCCCTGCTGGCTCAGAGTCGAGCACTAGGTATCAAGCCGATGCCCATGCTCGACCCGAACGTCCCGATGAACCAACAGATGTCACTGCTGAAGTCGAATATACTCGCCGCGCAGTATATCGAGTCGGGCGGGGACGAGAAAGCGCTGAATAAGTTCTTGCAGGAGAAATTCAGGGGTACCTTGAGCGACTCCAGTACAGTCGATGCCTCAACAGATTCTGATAACCTTACAGATTCGAATCAGACTGATTCAGAGATGGAACTCGAGACCAGCGTCAGCAAGAAGCAGAAGCATTACGACGAGAGAGCATTACGACTGCCTTTAGAAAGAGGTTGGAAGAGGGAGACTATAATAAGGGGTGTCTCAAAAAGTGGTGGTATAAAAGGCGATGTGACTTACATAGCTCCCGACTCGAATAATAAATTTAAGCAGATGTCGGACATAACGCAGTATTTGGATTATCAGAAGAGTATTGAGCTGACGAGGGAGAATTTTACATTCAGCAGCCGGGTGATCATCGGTGACTACATACAGCCGATGCCGCCTGAACTCGGGGGCGACAACGAGAGCATCCGGCTGACGGAGGATGAAGTTCTTCGAAGGTTGGAAGAGATCAAAGCGGCGATGAGGACCAGCCTACCTGTAGAGACCCGGATAGAGGTCGCCCGACGACAGCAGGCTGCCAGAGCCGCCGCACGGATGGACCGAGAGCAGGCCCGCATACAGCGAGAGATCGAAAAATCCGAACGCCAAGAAGCCGCAAGGAGAGACCGCGAGGCGAAAACGCAACAGCTACTCGAGGCAAAGCGAAAAAGGCAGGAGGAAATTGAAAAGCACAAGCAGGAAGAGCAGCAGCGTAAACAGCAGGAGAGAGAACTGAAAAGACAGCAAAATGCTATTTTAAAAGAACAGATGTACATACAGGAGATCAGTAAACAGCGAGAAATACTCTACACTGTCGAATTGGAGAGAGAAAGACGAAGACAACACATGGCTCTCGTAAAAGCGTTGGAGAGCCGACGTAAGCTCGAAGAACGCGAacgtaaaaaacaacaaatgttAGCCGAGAAACAAGCGAACAAAGAGAAAAAACTCGAACAAAGACGTATAGAAATGGAAATACTCACCGAACTCAGGAAACCTTGCGAAGACTTAGAACTAGATCAAAAACGCCTGCCCGATTACGACCGAATACCGGGGTTAAAACTGCCAGGGAAGGCCTTTGCGGACATCCTGATGGTCTTCGAGTTCCTCCACAATTTCGGGGAAACCCTTGGCTTCGATATGGAGAGCCTGCCGACGTTAGACTCGTTACAACAGGCGTTACTCTACAACGACACGAATTGCGAAGCTGAAGAGGAACTGCTGTCTGTTATGACGCATCTTATCGTCTGCGCGATCGAAGATCCGGGGATTCCCAACCCCGCGCGTCACACTACCATCCTAGGTCAAAGTTTACGACAAGCCGATATCACACACGCGAATATTACCGAGATTTTGCGGATTTATCTGTACGCTAACGCGACCGGAGAGGTTAAAGCGCTGACGGGGGTGCATTTCGAGCGAGATAGGGAGAAGAGGGTGGCTGACCACCACCAGAACGACTGCGAGATGCAACAGACGCAAACGGGGAAGAACGCGACTTATTACGAACAGTTGCACGAGAACGCGACGTGGAAAATGTCGGATATGTTGAAGGATAAACCGTTTTTGTCGCTGTCGCCGACGGATAAAGCGGCGATTTTGGCGTTTCTGTGCAACGAATTGCTCCAGAACAAGGCTGTGATCAGGCAGATCGAGGGGTCCTTGGAGACGGTGGCGCAGTGCAAGAAGGACAAGTGGTTATTGGACGCGAAGATCAGAAAGTTACGCATGCTCCACAGTCGCAAGATACGCTCCGAAGCCGTCGAGAAGGCCGTCGCAAAACTAGACGGCGAAGCGGGCGAAGCACCGCCCATCGACTCGCCCGCCATCCACAAAGACCACGACCACCTCTTAGACCACGACGACGAGGACAACGACATGAGCGAAAACGAGAGCGTCATCACGcaaccagaagaagaagaagacaaCAAATTATCGGGCGAAGAACTCGGCAAAAAACTAGAGAAAATCCAGAAAGCCGCCGAGGTACAACTGCAATCTTTAAACACCTCGGCGCACCAACTTCGCGCGACCTGTTTCGGCCAAGATCGCTTCTGGAGGAGGTATTGGTCGTTACCACGCGCTGGGGGTGTGTTTGTCGAGGCCATGGAGTCCGCAGAACCCGAGATGATTGATGGAATGGTTGATGGGGGTGATATAAGTCATGGGGGAGATGTAAAAGGTGTGATTGAGGCAAGAGATGGTGGTTTGAGAGATTGCGGTATGGGAGATTGTGGTACGAGAGATTGTGGTGCAAAAGATTGTGGTACAAGAGATTGTGGTACAAGAGATGGTGCTACAAGAGATTGTAGTACAAAAGATGGGCTTGATATTGAAGGGGAGAGCCCAGGAAAAGATATAAGGAGTATTGAGGACATCAAGAAGATCATTCACACCGTCGAAGAAGTGTGTGGTCTCCAACCCGATAAAGAAGTGAGTTCGATCGTCGGGAACGAGATTAACGACGAACAAGACGCAATAAAAGAAGATACGAGATTGGGAGACACATTGAACGAAGAATCTCCGACCACAgaggaaaaaataaacaacgaCACCGAAAACGAACACAGAAAAGTCGCCAATCGATTACTGGAGGAAGTAATCGAGAACGGCGACTCCGAAGAATCGAAAGAACGAAATTTGGACGAGTTGAGGAAAAGCGTAGACCGAATGGTGCAGAATCTAGAAGCAGAATCTCAAAACCACACGATCAAAATGGAACTTGAAGCCACGAAAACCGAAGAAATGACAAAAATCGAACAAGTAAAGCTCGAACCGATTATGAAAAAGCCGTTTAACCTCTTTGAAAAACTCGGGGAGTGCATGGAACGCGAGAACAAAACCGAGGAGGACCTTAAGGCCGAGGTAAAACCCGAGACGAAAGAAGAGCTCAAGAACGAAATCCTCAACGAGTTAAAAACCGAGATCAAGACCGACCCGGACGAGGAAACCCACGATAGAAAGTGGTTCTCGATCCTCCCGAAAGACAACCATACCTGTCTAGGGGTAAACCTAACCGCCGGGAACCGTTGGGACAACGGCGTCGGGGCTTGCACCAGAGACAACCTCACAGAACTAAAAATCCCCGTATTTCCCCCACCGAGTCACAATTCGACCTACATCCCGGCGAATTGCGATAGTCCGGCGCCTTTGCAGATGACCGCTGAGGAGATGGCGCAATTGGAGTATATAAAGGTGCACGGGTTGCCGCGGGCGTGCGAGAAGGCGGCGATACCGAGGGATAAGCGTTTCGGGTGGTGGAGGATCGCGGATACGGCGGTGATGCGCGACGTGTTGGATAATCTGCATGTGCGCGGGGCTAGGGAGCGCGAGTTGAAGAGGAATTTCTTGACGGTGATGCAGACGATGTACGAGGATCAGACGCAGTTGCATATCGAGGAGGGCGAGAGGGAGTCGACGGAGTTGCGTCCGATGGAGTGTGAAAGTGTGGAGATGCTGGAGGATGTTGGGGTGCCTGCGCCGAATGCGACGGGGTTTTGGAGCCGGACGGTGGCCAAGCGCGTCGATATCTTTCTTCTAGAGCAGGTTGAAGCTCTTGAAGACAAGGTGGCGAACGCAAGCATGCAAATTAAGGGCTGGCGACCACCCAGCCGGGATGACAACGAGACCCCGGAAGGTGACATCGTCGCCATGGCGAAAGACCGCTTGATCGCTTTGGAGGCCGCCATCGAGAGGCGGTATCTCAAACCGCCTCTAGGCGCAAGTACCGGCGATCCAAATTTAGCCGCTATAGCGCAAGAGGCGGCGGGCAATCCCGCCCCCGTCCAACCCGCCGCCTCGTTCGACGAGATACCCAAGGGCCTGACCGTGTGGCGGGAGGCAATCAACCGCTCGGTGACCTCGGCACAGCTGGCCATGTGCCTCTACTCGCTGGAGGCCTCCATCGCGTGGGATAAGAGTATTATGAAAGCTGTGAGCCCCCCTCATGTGTTTAATAAACAGAGAGCCCGCAAATATAACAGCAAGCTGAGTAACTGCCAGTTCTGCAACAGTGGGGATAACGAGGACAAGCTCTTGTTGTGCGATAGTTGTGATAAGGGGTATCACACTTATTGCTTCAGGCCGAAGATGGATAACATACCGGACGGTGACTGGTACTGCCACGAGTGTATGAATAAGGCGACGGGTGAACGGAATTGTATTGTGTGTGGGAAAAAGCAGTCTTTGACGGGGACGAAGCTCATCTTGTGCGAGATCTGCCCGCGGGCTTATCACACGGATTGCATACAGCCGTCGATGGGTAAGGCGCCGCGCGGTAAGTGGTACTGTATAAATTGCATCTCGAAGAAGCCGCAGAAGAAGCCGGTGCAGAAGAAGAGCAAGCCGACTAGGGATAGCGAGTCGTCGGATCACCATCCGGCAAGTCCAGCGCCGTCCCATAGTTCCGTGACGACCAACGAGGACAACAACCCGCCGATCCCGTGCAACCAGAGCGACATCTCCAACTCTAGCATCACGATAACGGGCTCGCCGTCCACGCAGTGCGTCGTCAAGAAAGACAAGATCTCCAAGAAGCTCCTCAAGGAGTTAGCGCCGTGCAAATCGATCCTCGAGGACCTCGAATGCCACGACGACGCCTGGCCATTCCTCCTACCCGTCAACACAAAACAATTCCCCACCTACAAGAAGATAATCAAGATTCCCATGGATTTGTCGACGATCAAAAAACGTTTACAAGATTTAGtttACAAATCCAGGGAGGAATTTTGTGCGGACGTCCGACAGATCTTTAATAATTGCGAGACGTTCAACGAAGATGACAGCCCGGTCGGTAAGGCAGGTCACTGCATGCGCCAGTTCTTCGAGGCCCGCTGGAACGAGCTGTGCGCTTCCCACAGTTGA
Protein Sequence: MDKENGKSSDGGSGSSKLSNPTDPTALLDAASLFAYWPRGDANSANAASLFASSGGAYGLPHPAMPFGMLPPTPGRGVPSFPPASSAAAGYSNAYTNTLSAAAASQAASLGLPAASAAWWSMASHLAAQDYLARLQATGLSFPGLGSPADPYAALGLPSLGGGGHHKSTKNSKSSSTSSSLPKSLQGSSSTKDKSSTKSSNDARSDIKTSSPMPNSKSSSSSTTPKYSNSGIGGYGGQGMKMPSTSTNSTTTTVSSMGSNGEKKSQRMLQQQQNSGELKYGERTKSASSPSPSIFTNPLSMASNDRGTPTNSATSTPPPGTSGNAAVPGIPASILSDPNSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPSVSLHPSLSSTGMLIESRSSKRQKLDLSDMGSPASPGDRVEVIKLPATNGSPSGISSLNSSGNNLDSSADGPLNLSLKPATSTPTNHHTSSSLNSLSNMSANIGMDRISRRKPGPKPRKVIQSPSLPPSASPSASLAQLFAPIDSSRPPSRTDPMDGSLNNSTSPGMSLPAPNHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPMPMLDPNVPMNQQMSLLKSNILAAQYIESGGDEKALNKFLQEKFRGTLSDSSTVDASTDSDNLTDSNQTDSEMELETSVSKKQKHYDERALRLPLERGWKRETIIRGVSKSGGIKGDVTYIAPDSNNKFKQMSDITQYLDYQKSIELTRENFTFSSRVIIGDYIQPMPPELGGDNESIRLTEDEVLRRLEEIKAAMRTSLPVETRIEVARRQQAARAAARMDREQARIQREIEKSERQEAARRDREAKTQQLLEAKRKRQEEIEKHKQEEQQRKQQERELKRQQNAILKEQMYIQEISKQREILYTVELERERRRQHMALVKALESRRKLEERERKKQQMLAEKQANKEKKLEQRRIEMEILTELRKPCEDLELDQKRLPDYDRIPGLKLPGKAFADILMVFEFLHNFGETLGFDMESLPTLDSLQQALLYNDTNCEAEEELLSVMTHLIVCAIEDPGIPNPARHTTILGQSLRQADITHANITEILRIYLYANATGEVKALTGVHFERDREKRVADHHQNDCEMQQTQTGKNATYYEQLHENATWKMSDMLKDKPFLSLSPTDKAAILAFLCNELLQNKAVIRQIEGSLETVAQCKKDKWLLDAKIRKLRMLHSRKIRSEAVEKAVAKLDGEAGEAPPIDSPAIHKDHDHLLDHDDEDNDMSENESVITQPEEEEDNKLSGEELGKKLEKIQKAAEVQLQSLNTSAHQLRATCFGQDRFWRRYWSLPRAGGVFVEAMESAEPEMIDGMVDGGDISHGGDVKGVIEARDGGLRDCGMGDCGTRDCGAKDCGTRDCGTRDGATRDCSTKDGLDIEGESPGKDIRSIEDIKKIIHTVEEVCGLQPDKEVSSIVGNEINDEQDAIKEDTRLGDTLNEESPTTEEKINNDTENEHRKVANRLLEEVIENGDSEESKERNLDELRKSVDRMVQNLEAESQNHTIKMELEATKTEEMTKIEQVKLEPIMKKPFNLFEKLGECMERENKTEEDLKAEVKPETKEELKNEILNELKTEIKTDPDEETHDRKWFSILPKDNHTCLGVNLTAGNRWDNGVGACTRDNLTELKIPVFPPPSHNSTYIPANCDSPAPLQMTAEEMAQLEYIKVHGLPRACEKAAIPRDKRFGWWRIADTAVMRDVLDNLHVRGARERELKRNFLTVMQTMYEDQTQLHIEEGERESTELRPMECESVEMLEDVGVPAPNATGFWSRTVAKRVDIFLLEQVEALEDKVANASMQIKGWRPPSRDDNETPEGDIVAMAKDRLIALEAAIERRYLKPPLGASTGDPNLAAIAQEAAGNPAPVQPAASFDEIPKGLTVWREAINRSVTSAQLAMCLYSLEASIAWDKSIMKAVSPPHVFNKQRARKYNSKLSNCQFCNSGDNEDKLLLCDSCDKGYHTYCFRPKMDNIPDGDWYCHECMNKATGERNCIVCGKKQSLTGTKLILCEICPRAYHTDCIQPSMGKAPRGKWYCINCISKKPQKKPVQKKSKPTRDSESSDHHPASPAPSHSSVTTNEDNNPPIPCNQSDISNSSITITGSPSTQCVVKKDKISKKLLKELAPCKSILEDLECHDDAWPFLLPVNTKQFPTYKKIIKIPMDLSTIKKRLQDLVYKSREEFCADVRQIFNNCETFNEDDSPVGKAGHCMRQFFEARWNELCASHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00137942;
90% Identity: -
80% Identity: -