Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 8e-05 0.5 10.0 0.1 21 48 37 64 31 68 0.84

2 10 0.00011 0.66 9.7 0.1 21 44 65 88 60 92 0.90

3 10 4.9e-05 0.31 10.7 0.1 21 48 93 120 88 124 0.84

4 10 0.0001 0.62 9.7 0.1 21 44 121 144 116 149 0.90

5 10 5e-05 0.31 10.7 0.1 21 48 149 176 144 180 0.84

6 10 5e-05 0.31 10.7 0.1 21 48 177 204 172 208 0.84

7 10 5e-05 0.31 10.7 0.1 21 48 205 232 200 236 0.84

8 10 5e-05 0.31 10.7 0.1 21 48 233 260 228 264 0.84

9 10 4.5e-05 0.28 10.8 0.1 21 51 261 291 256 293 0.84

10 10 0.044 2.7e+02 1.3 0.1 21 43 289 311 284 320 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	8e-05	0.5	10.0	0.1	21	48	37	64	31	68	0.84
2	10	0.00011	0.66	9.7	0.1	21	44	65	88	60	92	0.90
3	10	4.9e-05	0.31	10.7	0.1	21	48	93	120	88	124	0.84
4	10	0.0001	0.62	9.7	0.1	21	44	121	144	116	149	0.90
5	10	5e-05	0.31	10.7	0.1	21	48	149	176	144	180	0.84
6	10	5e-05	0.31	10.7	0.1	21	48	177	204	172	208	0.84
7	10	5e-05	0.31	10.7	0.1	21	48	205	232	200	236	0.84
8	10	5e-05	0.31	10.7	0.1	21	48	233	260	228	264	0.84
9	10	4.5e-05	0.28	10.8	0.1	21	51	261	291	256	293	0.84
10	10	0.044	2.7e+02	1.3	0.1	21	43	289	311	284	320	0.83

Coding Sequence: atggaacAACAAAAGACATACACAGAAAAAAAGCCATACCAATGTGAAGTGTGCAATAAATCGTTTTTTCGAAATTTTGATCTAAAAGTATGTCATCGAACTCACACGGGAGAAAAGCCATACCAGTGTAATGTTTGTGGCAAATCGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACAATAATCTGAAACGTCATCAGCGAACGCATACGGTAGAAAAGCCATACCAGTGTAACGTTTGTGGCGAATTGTTTACTCAAAACATAAGTCTGAAATTTCATCAGCGAACACACACGGGAGAAAAACCATACCAGCGTGATGTATGTGGCAAATCtttctttcaaaatattcatttaacaaCAAATCGTCGAACTCACATGGGAATATTGGCGTAA
Protein Sequence: MEQQKTYTEKKPYQCEVCNKSFFRNFDLKVCHRTHTGEKPYQCNVCGKSFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNNNLKRHQRTHTVEKPYQCNVCGELFTQNISLKFHQRTHTGEKPYQRDVCGKSFFQNIHLTTNRRTHMGILA

Sequence clustering based on sequence similarity using MMseqs2