Basic Information

Insect: Aphis gossypii
Gene Symbol: -
Assembly: GCA_004010815.1
Location: NW:99455-111444[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.5e-06 0.00027 20.7 3.6 1 23 231 253 231 253 0.98

2 14 0.00036 0.027 14.4 3.7 1 23 259 281 259 281 0.97

3 14 0.00094 0.071 13.1 1.8 1 23 370 392 370 393 0.94

4 14 0.00012 0.0088 16.0 1.1 1 23 427 449 427 449 0.98

5 14 0.33 25 5.1 1.9 2 23 467 488 466 488 0.90

6 14 0.025 1.9 8.6 0.1 2 23 499 521 498 521 0.91

7 14 0.002 0.15 12.1 2.0 2 23 529 550 529 550 0.97

8 14 0.0029 0.22 11.6 3.0 5 23 559 577 556 577 0.93

9 14 0.0059 0.44 10.6 0.0 3 23 584 604 582 604 0.95

10 14 1.6e-05 0.0012 18.7 0.2 1 23 620 642 620 642 0.98

11 14 0.00045 0.034 14.1 0.2 3 23 650 670 648 670 0.97

12 14 1.2e-05 0.00087 19.1 0.1 1 23 676 698 676 699 0.95

13 14 0.00038 0.029 14.3 1.6 1 23 712 734 712 734 0.96

14 14 2.9e-06 0.00022 21.0 0.1 2 23 1010 1032 1009 1032 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.5e-06	0.00027	20.7	3.6	1	23	231	253	231	253	0.98
2	14	0.00036	0.027	14.4	3.7	1	23	259	281	259	281	0.97
3	14	0.00094	0.071	13.1	1.8	1	23	370	392	370	393	0.94
4	14	0.00012	0.0088	16.0	1.1	1	23	427	449	427	449	0.98
5	14	0.33	25	5.1	1.9	2	23	467	488	466	488	0.90
6	14	0.025	1.9	8.6	0.1	2	23	499	521	498	521	0.91
7	14	0.002	0.15	12.1	2.0	2	23	529	550	529	550	0.97
8	14	0.0029	0.22	11.6	3.0	5	23	559	577	556	577	0.93
9	14	0.0059	0.44	10.6	0.0	3	23	584	604	582	604	0.95
10	14	1.6e-05	0.0012	18.7	0.2	1	23	620	642	620	642	0.98
11	14	0.00045	0.034	14.1	0.2	3	23	650	670	648	670	0.97
12	14	1.2e-05	0.00087	19.1	0.1	1	23	676	698	676	699	0.95
13	14	0.00038	0.029	14.3	1.6	1	23	712	734	712	734	0.96
14	14	2.9e-06	0.00022	21.0	0.1	2	23	1010	1032	1009	1032	0.96

Sequence Information

Coding Sequence: ATGAGTGTCGATTATCGACATTACGCGTTTCTGTTTCTACTCCATGAGCAGAGGTCGACCGCGACCCGCCGCACCATTGCCGTGATGGCCATGATGATGCGGTGGCGGTGCGGGGTCAGTGGAGGATTTTCGACAAACGTAAatttgtatacgtataatggCGTCATATTCCTGTCCATCGGTGTTAACGCGTTCAAATACGTGTTCTACGGCGGAAAACGACCAGGAATAACGTACTTCGGAGTAAGTCCGACCAACGGTTGCACGGCGGGTGGTACACGCGAAAATGAGCTCAATAATATGACTAGAGCGGTCATGGAATCTGTGCCATATGCCGATGGGTTACAATACTTAGCTGCCATATCTTCATTCAGTGATAATTTTAAGgaAATGGATTCTGGGCAGCAAATTAAACAAGAGCCTGTTGACccaaatgatttatttgagTCTAGTGATGAGGAAGTTGTCCAACAAATGAGCCAAGAGGAATATCAAGAATTTTTTGATGTCCAAGAAGAAGTTGTTGTTCAAGAATGCCCCGAGCAAGAGATAATCACTCAAAGTTGGGACATGAATCGCTCTACCAATATTATCACcatATTAGAAACAGAAGTTGAATGTATGTCATCAACTGATGATGTTGACATACCAATACCTGAAGGCGAAGAAGCTTCATCTTCTGTTAATCCATATCCATGTGATTTTTGTAGTCGGAGATTTAATCGAAAATCACATCTTATGAACCATATGGTTACCCATCAATCTGAGCGTCCCTTTTGTTGTGCATTATGCGGTGTTCGTTATCGACGTAAATGTGATTTAGCTAATCATATGAAAATTCATATTGGTCCTGATAATCAATCAGATAGTGGTctagataaTCAAAATGTATCTGTTACAAaagtaatgaataaattaatgttcgtGGATCCAATACATAGAAGGAGTGTTACACCTGGTGATGATTCTGAAGACAAAGGAGACACTTTTCAAGAACCAAGTACAAAAAATCGTGGCCGTAGTAAAGGTCGAGGTAGAGGAAAAGGTCGTCCAATGAAAGACCGCTTAATTACTCTTGGTTGGAATTcagaaatttattcaaaaccaCATACATGTAACCCATGTGGAATTTCATTTACACGTGAAAAAGCACTTCTTAATCATGCTCGTCTTCATCATATTGATGATGgtgtaaatattgtaactactcaaaaatcaaattcagATAGTTATGAGCTTACAATATTGGCTAATTCTAAATCCAGTGATGTGACTACCTACTCTTGTGATTCTTGTGGAGCAATATTTGAcagatttgattttttaaaacgtcATCAAAGgcAGCATATGAAAAAAGAACTTGGAAATGTTGAAGAAGAAATTTATGAAGAAGCGCATATGTGTATACATTGTGGATTGTTCTTTAAGTCTATGCCTGAGTTAGAAATGCATACTGATCAACATTTGATTCCTACAAATATTTctgaaaaatcaaaatgtttagcTTGTGGTGAAACATTTGATAGTACAGATGAGTTGTCTGATCATGTGTCTCAAATTCATACCGAATCATTATCTGAAAATTCTTGTAAACTTTGTGGAAAACTATGCAAAGATGATAAAGCTCtccaaaaacatttaatggtTCATGACACGtctgataataattgtataatgtgtgGTAAAAGATTTCATTCCAGAGCACGTCTTAAACGtcatATGGTAACTCATCGAGAAAAAGGAGTTATTTGTGACATTTGTGGTGAAGAAGTAGCCGACAAACGAGCacttattaatcataaagCCAGTCATGCAAATACTGTTAGTATTTCACAAAATTCACTGACTGAAAAAGTATTTCCATGTACTAGTTGTGGTAAAgtatttggATCTAGATCATCTCAACAAATACATATACGAATTCATACTGGAGAAAGGCCTTACGGTTGTAGATACTGTAGCAAAGCTTTTGCTGATGGTGGTACTCTTCGAAAACATGAACGAATACATACTGGAGAAAAGCCATACGCTTGTCCTGTCTGTCCAAAAGCATTCAATCAAagagttGTATTGCGTGAACATATACGAGCACATCATGCTGGAACTGAGGCTAAGGGTGgtcaagttaatttttatgaatgtaaAGTATGTGGATATTTGTTCCGATCTTCAATGGAGCTTTGTTCACATTTAGTTCAGCACAGTGATGAAAATACTAAAAGATCTAGAGTAGTAcctGTTGGACCTCGCAAGTATAAGCGTCGCAGCAAGTTGGGTAATCGAAAAGACACATGGTGCTTAGTAGAAAAAGTGTTCACAGTTATGTCAGGACAGTCGGATACTGAGAGCTGTGAAGACGAACCCATGCCTACAGTAGAAGAGCAAGCTGTACAATCAATAATGGAACAGGATGATATGCCTTATGATCCACCTACTATAGCTAGTCCTCCTAGTAAGTCTCCTgttaaaacatacaaaattgtTAATGGCAAGTTACTGAAAAGTGAACAAAAGTCTTCTAAACAAGTTTCATGTGAATCAAAACACACGATTCCTAAGTTGGAACCTGTACCCAAAAAGCATAGTTTTGTGCTTAAAGACGGAGAGTGTACTAGAACTTGTTCAACTGTTCTTTATTATTCTTCAAGATCTGATCCCACAGTTATGGATTCGTCATTAGGAGAGGAATCAAAAGAAAATGATAATCCAGAAGAACCTGAAGACCAGATATCTGTAGAGGACACagattttactaatattaaaattgagcCAGTTAGTGATCagtcaatatttaatgttcaCGATTTAGACAACATATGCAACATTGATTTTTCTGGTGAAAatgaagtacaatattatgtagagaATACTGATGACGGATATGGCGATCAATGTGAATTGATTCTGGAATCTTCAAATGATGATTGCTTGATTGAAACAGTGTTTGATACAGATTATGTTGAGGAAGTTGGTGCTAATATTGAACTGAGCACTGAAGAAATGGCACCTGTATTTGCAGAAATTATATCTTGTGATATTTGCGATGAAGTATTTGAGGATAGAAAGGAACTTATGAGACACATTCAAACCATGCACATTGGataa
Protein Sequence: MSVDYRHYAFLFLLHEQRSTATRRTIAVMAMMMRWRCGVSGGFSTNVNLYTYNGVIFLSIGVNAFKYVFYGGKRPGITYFGVSPTNGCTAGGTRENELNNMTRAVMESVPYADGLQYLAAISSFSDNFKEMDSGQQIKQEPVDPNDLFESSDEEVVQQMSQEEYQEFFDVQEEVVVQECPEQEIITQSWDMNRSTNIITILETEVECMSSTDDVDIPIPEGEEASSSVNPYPCDFCSRRFNRKSHLMNHMVTHQSERPFCCALCGVRYRRKCDLANHMKIHIGPDNQSDSGLDNQNVSVTKVMNKLMFVDPIHRRSVTPGDDSEDKGDTFQEPSTKNRGRSKGRGRGKGRPMKDRLITLGWNSEIYSKPHTCNPCGISFTREKALLNHARLHHIDDGVNIVTTQKSNSDSYELTILANSKSSDVTTYSCDSCGAIFDRFDFLKRHQRQHMKKELGNVEEEIYEEAHMCIHCGLFFKSMPELEMHTDQHLIPTNISEKSKCLACGETFDSTDELSDHVSQIHTESLSENSCKLCGKLCKDDKALQKHLMVHDTSDNNCIMCGKRFHSRARLKRHMVTHREKGVICDICGEEVADKRALINHKASHANTVSISQNSLTEKVFPCTSCGKVFGSRSSQQIHIRIHTGERPYGCRYCSKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHAGTEAKGGQVNFYECKVCGYLFRSSMELCSHLVQHSDENTKRSRVVPVGPRKYKRRSKLGNRKDTWCLVEKVFTVMSGQSDTESCEDEPMPTVEEQAVQSIMEQDDMPYDPPTIASPPSKSPVKTYKIVNGKLLKSEQKSSKQVSCESKHTIPKLEPVPKKHSFVLKDGECTRTCSTVLYYSSRSDPTVMDSSLGEESKENDNPEEPEDQISVEDTDFTNIKIEPVSDQSIFNVHDLDNICNIDFSGENEVQYYVENTDDGYGDQCELILESSNDDCLIETVFDTDYVEEVGANIELSTEEMAPVFAEIISCDICDEVFEDRKELMRHIQTMHIG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01167906;
90% Identity: iTF_00135598;
80% Identity: -