Basic Information

Insect: Aphidecta obliterata
Gene Symbol: topi_1
Assembly: GCA_963966015.1
Location: OZ014427.1:8128723-8132054[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0021 0.22 12.6 2.1 2 21 126 145 125 146 0.94

2 14 9.8e-05 0.01 16.7 2.5 1 20 171 190 171 193 0.94

3 14 0.0087 0.92 10.6 2.0 3 23 201 221 200 221 0.95

4 14 0.0042 0.44 11.6 0.3 2 20 240 258 239 260 0.92

5 14 1.4e-05 0.0015 19.4 1.0 2 23 315 336 314 336 0.97

6 14 4.8 5.1e+02 2.0 0.1 1 13 342 354 342 363 0.82

7 14 0.0011 0.11 13.5 2.7 2 22 379 399 378 402 0.89

8 14 0.45 48 5.2 0.0 1 23 522 545 522 545 0.91

9 14 0.12 13 7.0 0.9 1 23 549 571 549 571 0.91

10 14 7e-07 7.4e-05 23.5 2.4 1 23 577 599 577 599 0.98

11 14 0.019 2 9.5 0.2 1 23 605 630 605 630 0.96

12 14 0.33 34 5.7 2.5 1 23 636 658 636 658 0.85

13 14 4.6e-05 0.0049 17.8 1.6 3 23 666 686 664 686 0.97

14 14 4.7e-07 5e-05 24.0 0.9 1 23 692 715 692 715 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0021	0.22	12.6	2.1	2	21	126	145	125	146	0.94
2	14	9.8e-05	0.01	16.7	2.5	1	20	171	190	171	193	0.94
3	14	0.0087	0.92	10.6	2.0	3	23	201	221	200	221	0.95
4	14	0.0042	0.44	11.6	0.3	2	20	240	258	239	260	0.92
5	14	1.4e-05	0.0015	19.4	1.0	2	23	315	336	314	336	0.97
6	14	4.8	5.1e+02	2.0	0.1	1	13	342	354	342	363	0.82
7	14	0.0011	0.11	13.5	2.7	2	22	379	399	378	402	0.89
8	14	0.45	48	5.2	0.0	1	23	522	545	522	545	0.91
9	14	0.12	13	7.0	0.9	1	23	549	571	549	571	0.91
10	14	7e-07	7.4e-05	23.5	2.4	1	23	577	599	577	599	0.98
11	14	0.019	2	9.5	0.2	1	23	605	630	605	630	0.96
12	14	0.33	34	5.7	2.5	1	23	636	658	636	658	0.85
13	14	4.6e-05	0.0049	17.8	1.6	3	23	666	686	664	686	0.97
14	14	4.7e-07	5e-05	24.0	0.9	1	23	692	715	692	715	0.98

Sequence Information

Coding Sequence: ATGAGAGACTCGGATAATCTTATTTTCAAAGTATACAAGATCAACGAGAATGGAATTATTTCAGCAGTGGAATATGAACAGGATTTTTATACCCGCGAAGTTCTATCAAAAAGGCACATTCCACATCAGGAACCAACTCCAAATTTACATTATGACCCGGAAAAGCTGAAATTGAGCTTCAGTAACTTCGAATGCGAGGACGAGGATAATCCCCTTATAAGTTTggtgaaaatcgaaaatattagCGATGTAAGTTTAATTCAGACCAGTGGATACTCTTGCCCGAAAAATGTTATACCTCGAGCTAGAAGAAGTGCTTCACCGTGTTATTTACATCATCAAATGAGGATCTCTTTGAATATACCCACTATGATAAGGTGTCAAAATTGTGAAACAAACTTCCCCACAAAATATCAATACCAGAGGCATCAATGCGAATTTAATGCAGAAAAAGTAGTTCTGAAAGCGAATGCTGATTTGAAAGATATAAACAAAGGAATGAGGATCAAGTATGATTGTGAGAGATGCGGAAAACAGTTTGTAAGTAAAAACAATTTGGAGAGACATCGAATTTgtcacgaaaattcgaaagaaaacATATGCGAGCATTGTAATAAACAGTTTGTTAGCGAAAATAGATTGAGAATACATAAAGAAAACCACTGTAAAAAGGTAGGAGATATATCCAAGTTTTATCGTAGTGATGTAGCCGTTTGGAAATGTAAGAAATGTCATGAAGTGTTTTCCTCATTGAATTCTGCAAACGCCCATTTGGAATCTTGTAAAGAAGATTTGTTTGAATTTAATCAAACTAATTCTAAAGATGATGCAGATATTCCGAAGGAGGAGGGCTCTAGTGTGGTAACTTTAATTGATGATGATTCGAATGCAAAACTGTTAGATGAGagccaaattgaaaaaattctcacaGAAATTTTGTTACAGTGTGAATTTTGCAATAGAACATACGCTGATAAAAGCTTACTCCTGTTACATCAAAGAAAACATTCTACTTCCAAAAATTACGAATGTGTCAACTGTAATAGTAGCTTTGAATCGTACGCGGTTGCTGCTCAGCACTGGTTGAAAATATGCTCTGAAACTTCTAATATGTTTTATCTTCCCAAATTAACTTATTGCGAATACTGTGATCGTACATTCAAATCTCATGAATTATTATATGCacataaaatcaagaaaaaacatTATACGGTCAAACTACACATGAATGATTCAGTTTGCAACAGGGCTAACATGAGAGAAAAACAAATTGATAGTAGTGAAGCCATAAACAAACTCATCGAAGATGTTTTGATAACATTAGACAGGCCCATAAGTAAAATCTGCCAACTGACTAAGATCAATTACGATGTTTCAAAtaaggaaaatattgaaatggaaGGTTCTTACACGCAGAGGGATTTCAGTGATGCGCCTGAAGAATCCATGCACAACGAGCTTTCCGACAAACCCGAGAAGAGGAAGCGGGGGCGAAAgagaaaatattccaaacctggcATCAGGAGTAAAAAGCTTCAACACCTGATAAACGAGGGATACAAATATCAATGTGAGCGTTGCCCAATTGTGTGGGATAATGTTACCGATTTGGAGAAACACAGGGATGAAGAGCATGCAGCAAGTTTCAGTTGTGAAGATTGTGGGCAGATATTACATAGTGCCAAAGCATTGCTTATCCATTGTCGAGCTCATAAGTGTTTGAAACCGTATGTTTGCGATACATGTGGCAGAAGTTATTCCCAGACATCTCATCTATGGCAACATATGAGATTTCATCAAGGCATAAAACCCTTTGCATGCCCCCATGAGGGGTGTGAAGCGAGATATACTATTCGCCCAGATCTAAAGGACCATATACGAAAAGTGCACACCAGGGAGAGACCCTTCAAATGTGCAGTTTGCAATAAATGCTTCCTAACAGGTTCTGTTTATTATCAACATCGTTTAATCCATACGAACGATAGAAGATATGGATGTGATGTTTGCCATAAGAGATTTTTCAGAGCTGACGCTTTGAATAATCATAAGAGAATTCATACCGACGAACGTCCATATCCGTGCAATGTGTGCGGAAGAGAATTCAGACAGAAAGGCGATCGTAATAAGCATATGCGTACTCAACATCCTGAAGCTGTCATCCAGTAA
Protein Sequence: MRDSDNLIFKVYKINENGIISAVEYEQDFYTREVLSKRHIPHQEPTPNLHYDPEKLKLSFSNFECEDEDNPLISLVKIENISDVSLIQTSGYSCPKNVIPRARRSASPCYLHHQMRISLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKANADLKDINKGMRIKYDCERCGKQFVSKNNLERHRICHENSKENICEHCNKQFVSENRLRIHKENHCKKVGDISKFYRSDVAVWKCKKCHEVFSSLNSANAHLESCKEDLFEFNQTNSKDDADIPKEEGSSVVTLIDDDSNAKLLDESQIEKILTEILLQCEFCNRTYADKSLLLLHQRKHSTSKNYECVNCNSSFESYAVAAQHWLKICSETSNMFYLPKLTYCEYCDRTFKSHELLYAHKIKKKHYTVKLHMNDSVCNRANMREKQIDSSEAINKLIEDVLITLDRPISKICQLTKINYDVSNKENIEMEGSYTQRDFSDAPEESMHNELSDKPEKRKRGRKRKYSKPGIRSKKLQHLINEGYKYQCERCPIVWDNVTDLEKHRDEEHAASFSCEDCGQILHSAKALLIHCRAHKCLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDVCHKRFFRADALNNHKRIHTDERPYPCNVCGREFRQKGDRNKHMRTQHPEAVIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00349527;
90% Identity: iTF_00764961;
80% Identity: -