Amia023687.1
Basic Information
- Insect
- Aphaenogaster miamiana
- Gene Symbol
- -
- Assembly
- GCA_003063725.1
- Location
- NJRN01000425.1:129305-132412[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0033 0.38 11.8 3.4 2 23 432 454 431 454 0.95 2 13 4.3e-05 0.0049 17.7 0.5 1 23 460 482 460 482 0.98 3 13 4.8e-06 0.00055 20.7 2.6 1 23 488 510 488 510 0.96 4 13 0.00015 0.017 16.0 1.9 1 23 519 541 519 541 0.97 5 13 2.2e-05 0.0025 18.6 2.3 1 23 547 569 547 569 0.98 6 13 5e-07 5.7e-05 23.8 1.6 1 23 574 596 574 596 0.98 7 13 0.0038 0.43 11.6 4.0 1 23 603 625 603 625 0.99 8 13 0.0003 0.034 15.1 0.1 2 23 645 666 644 666 0.97 9 13 2.9e-05 0.0033 18.2 0.7 1 23 672 695 672 695 0.97 10 13 0.15 17 6.5 1.4 1 23 701 723 701 723 0.95 11 13 0.00052 0.059 14.3 3.4 1 23 729 751 729 751 0.98 12 13 9.9e-06 0.0011 19.7 4.1 1 23 757 779 757 779 0.98 13 13 1.8e-05 0.0021 18.9 0.4 1 21 785 805 785 806 0.94
Sequence Information
- Coding Sequence
- ATGAGAATCGTTTGCGCCGCATCAAATTGCAAATATGCCTCGGAAAGCGAGGATTCATCGAGTGtcacttttatcaattttcccAGCGATGATACAGCTAAAGTATGGGCAGAATGTTGCGGCAGATCGGATTTAGCCGCAAAGTCGAATGCGGAATTGCatttgaattattacatttgttctCACCATATTGAAGATCGCTGTTATGTAAGCAAAACTGGTCCCGTTATTATAGAAGAAGGTACCATCCCTACTCTATTCGGCACCGACTTGACTACTGGTGAAGACTCAATAAATATGTTTGATAAAGCACAGCGTCTCCAAGAAGTAGGTGATAGCGTGCCTCTAACATATTGCGATATGAATGTCGAGATAGACGAGTATCATGATATCAGATTTGCCAATTTATGTCGAATCTGTGGCAAGTCTGCTCTGGATGGAATAGACATGTTTACAGCCAAGGGCATAGAACTCAAATTAAAGGAAAGAATAAATCTGCATATGCCTATCTCGATTGACATAGACGATTCGTTGCCACAGAAAATATGTACAGATTGCTGCAATAAATTGGAAATTGCACACTCATTAGTCGTATCATGTCTAAGAACCGATATGCGTTTGaagaaatttctaaatattgagAAAGAGTCAGAATATGAGAATAAGTACAATGCATTGGTTGACGAATGTTCATTAGAGATAGTACAAGAAATGTGTGTAGATGATAATACGCATCCTAATTCATTTACTATAAATAAGATGATAAATCCTGATTCAGAAATAAGTTTGAGAggattagaaatacaaaataataattttcagagCATTGGGAAAAGTGTTGTGCCATTAGAATTCAGTACTCTAATCCAAACTTGCAGAGAAGTTAATAGTGAAAATAATGTGACTATTACGGAAGAAATATCAAAAGTTCAACAAGACATTCAGAAGATTCAGAATAGAAGTCTTAGCGTTTTATGTTTGCAGTGCCAAACTTTTTATGAAACACAGGAGATATTTGagaatcataaaatattttgtagcaAGGAGCAAAATGTCGctaaacatatagatatatttagaaCTGCAGAAAACGAAAAGTATGGGAACAAACAGGATAATCATGAAATAGAAAATTCCCAGACATGCAATAAAAGATTTGATGGCAAGCAAGTTATTGATAACGTTAAAAGCTGTGAATCAATGCATTGTACTGTTTGTAACCAAATATTCAAATGTCAGCAGGATTATGACAATCACAAATATCTTCATGGAAATCTTACTGAAGTGACTAAAAGATGTGGTCATTGTAAAAAAGTATATCATAACAGAAAGGACTTGTTAATTCACATCATGGAATCGCACGAGGGACGACTATTATTTAAGTGCTCTACATGCGATAAAACATACGAGAAATGGTCTAGCTTAGATATTCACGAAGCTACTCACAGAATAGATAAGCCTTATCTTTGTGATCTGTGCGGAAAAAGCTTTAAGCATTCCAATAATTTAAGAGGtcataaaagaattcatttggACGAATCTATAAAGAAAAGGCACGTGTGTGAGATCTGTGGTAATGCGTTCAGATCaggATTTCATTTGCGAGAACATATGAATCAACACGATGGCAACAGACCCTATTCTTGTGAACAGTGCGGAAAAACCTTCTACAAGAGAATTCAATTACGACAACACAAATTATCGCATGGCTCTAATAGGCACACATGTCCGATTTGCGGTGCAACGTTTAATCGTAGAGGGAACATGAACACGCACATGAAACGGCATAATAACGGTAATGGAGGATATACATGCAGtGTTTGTGCTTACAAATGTAAGTCTATGAGCGAATTGAAAATACACAGGAAAAAGCATACAGAGGAGGAAATAGTGGACAGCATTAAGAAGAAATGTACCGACAAGGAGATATGGCgttgtaatatttgtaataaaatattcccGAAGCGCGCTGTCTTGTTAAATCACGAGCGCGTACACGGAGATGATAAGTTTTACGAATGCGATGAATGCGGCAAGAAATTAGCAAGTAAAAGCTCGCTGATGTATCACAAGAAGTCGATGCATCTGAGAGAGAAATCGCACATGTGTCACTATTGCGGAGATTCGTTCGTTTTGAGAGAAGCGCGATTGATTCACGAGAGGATACATACCGGTGAACGTCCGTACGTCTGCAAGGTGTGCAATATGCGGTACAGATGCTCCAGTAATCTCAGCCAGCACATGAAGATCCACACGGGTCTGAAGCCGCACAAGTGCCATTTTTGCAACAAAGGTTTCACGCGCAAAGGTGCGCTAACCGTGCACGAGAGAATTCACACGGGCGTTAAGCCTTATCCTTGCGAGACATGTGGTAAAAGCTTCTCGCAGAAGAATGACATGTTAAAGCATGCCAAACGCACAACGGCAGATCGATGCAACGGAGCCAGCGCAACGAGATCTTCAAATGGGAAAAAGAATATGTTAAAGCATCCTGTGGTACACGAGCAAGATACCTTAGTAATTTCAAATGTCAATTCGTCACATATTCTTCAAGTTTATGTCAATACTAGCGTCTCTtcggaaattaaataa
- Protein Sequence
- MRIVCAASNCKYASESEDSSSVTFINFPSDDTAKVWAECCGRSDLAAKSNAELHLNYYICSHHIEDRCYVSKTGPVIIEEGTIPTLFGTDLTTGEDSINMFDKAQRLQEVGDSVPLTYCDMNVEIDEYHDIRFANLCRICGKSALDGIDMFTAKGIELKLKERINLHMPISIDIDDSLPQKICTDCCNKLEIAHSLVVSCLRTDMRLKKFLNIEKESEYENKYNALVDECSLEIVQEMCVDDNTHPNSFTINKMINPDSEISLRGLEIQNNNFQSIGKSVVPLEFSTLIQTCREVNSENNVTITEEISKVQQDIQKIQNRSLSVLCLQCQTFYETQEIFENHKIFCSKEQNVAKHIDIFRTAENEKYGNKQDNHEIENSQTCNKRFDGKQVIDNVKSCESMHCTVCNQIFKCQQDYDNHKYLHGNLTEVTKRCGHCKKVYHNRKDLLIHIMESHEGRLLFKCSTCDKTYEKWSSLDIHEATHRIDKPYLCDLCGKSFKHSNNLRGHKRIHLDESIKKRHVCEICGNAFRSGFHLREHMNQHDGNRPYSCEQCGKTFYKRIQLRQHKLSHGSNRHTCPICGATFNRRGNMNTHMKRHNNGNGGYTCSVCAYKCKSMSELKIHRKKHTEEEIVDSIKKKCTDKEIWRCNICNKIFPKRAVLLNHERVHGDDKFYECDECGKKLASKSSLMYHKKSMHLREKSHMCHYCGDSFVLREARLIHERIHTGERPYVCKVCNMRYRCSSNLSQHMKIHTGLKPHKCHFCNKGFTRKGALTVHERIHTGVKPYPCETCGKSFSQKNDMLKHAKRTTADRCNGASATRSSNGKKNMLKHPVVHEQDTLVISNVNSSHILQVYVNTSVSSEIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01408479;
- 90% Identity
- iTF_00126785;
- 80% Identity
- iTF_00128291;