Basic Information

Gene Symbol
-
Assembly
GCA_003063835.1
Location
NJRP01000128.1:86822-90315[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 3.1e-06 0.00036 21.3 0.7 1 23 71 93 71 93 0.98
2 14 8.6e-08 1e-05 26.2 0.1 1 23 99 122 99 122 0.95
3 14 0.013 1.5 9.8 0.6 1 23 128 150 128 150 0.97
4 14 1.2e-05 0.0014 19.5 3.9 1 23 156 178 156 178 0.96
5 14 0.00016 0.019 15.9 1.5 1 23 184 206 184 206 0.95
6 14 0.00015 0.018 15.9 3.8 1 23 212 234 212 234 0.96
7 14 0.00072 0.084 13.8 2.6 1 19 240 258 240 263 0.94
8 14 2.5e-05 0.0029 18.4 2.0 2 23 415 436 414 436 0.97
9 14 0.00019 0.022 15.7 2.8 1 23 442 465 442 465 0.96
10 14 1.8e-05 0.0021 18.8 0.7 1 23 471 493 471 493 0.98
11 14 1.4e-06 0.00017 22.3 3.6 1 23 499 521 499 521 0.98
12 14 0.18 21 6.3 2.2 1 23 527 549 527 549 0.87
13 14 5.2e-06 0.00061 20.6 1.0 1 23 555 577 555 577 0.98
14 14 8.1e-05 0.0093 16.8 0.5 1 21 583 603 583 604 0.95

Sequence Information

Coding Sequence
ATGTCCAGCAAGAAATCATCGACGCATCTTGGTGATTTGGACAAAAGATTGGAAAAAGACTATTCGGCAGATTCTCATGCGGACAACTCTGAGCAAACGCAGAAGCCTCAAGAGAAACACACGGTGGATTCTCGAGGATGTATAGAACAATCGGAACAACACGACGAATTAACTCACTCGAAGACGACGGAGGGTAATGGATACGCCTCTCATAAGTGTGGCGAGTGCGGGAAAGTTCTTTCCACGTCGTACAATCTGCTAATTCACCGCAACATTCATGCTGGCGTACGACCCTATATCTGTCCCGTTTGCGACAAGAGCTTCCGATCGGCATCCGGTCTGAACAGACACGTGCGTGACGTCCACGACGGCGTTAAAAATTTCGCCTGTGACGTTTGCGGCCGTCATCTCGCCTCGAGGGCGTCGAGGGACGAGCACAGACGCACACACTCCAGCGAGAGGCCCCACGTGTGCGAGACCTGTGGCAAGTCTTTCAAGCAGAAGGCGTCCTTGCACGTGCACCGGCTCTACCATTCCCAGGTCTTGCCGCATCGTTGCGATCTGTGCGACCGCGGTTTCAGGAGGAAACAGGAATTGGACAAGCACGCGTCCTGGCACTCCGATCGAAAGCCGCATGCCTGCGATATTTGCAACGAGCGTTTCCGCAGCAAAGGCTGCGTCGCTCGTCATCGGCGCACTCATACCGATCAGCGATCGCACGTTTGCACGATCTGCGGCGCCAGGTTCACTCAGGAGCGATATCTGAAGAGACACTGTGGGAGTTTACATCCGGCTGTACACACattaaagAATCACACTGTCACCCACGATCGAATAATGGCCCACAGTTATTTCCGCCAAGAGTATAAGGTGGGAGAGCGTAGAAGTAAAATCAATCCAATCCAAACTAAAATGTCCAATATAATCGACGGAGGTTCAGAGAATATTTCTTTTACGGATAATACTCGTAACGATAAATCAACCGAACGTTTGTCTCCCACAAACACATCTCCTAAAGTATTCTCATCAGATAAATTGACAAATGACAAAAGGAAGACAAATATAGAAGACAAAGGTTCTAATCCTGCTAGTCAAACGCAAGCAAGTTGCACAAAAAGAACAAAGGCCATGCGGTATACGCGGCAGGAACCTGCAGCGGAAGTGAACGAGTCTAATGAATATCTGGAGAAGAACGTCAAGCAATCCAAGTCCAAAAAGGCTGCTTGCACCAGCCTAGCGATGGTCTGCAAATTTTGTAATAAGAAGTTTCGTTCGCGAAAAAGTTATTGGGCCCACGTACGCATGCACTCGGGCGAGAAATCGTACACGTGCCACATTTGTGGGAAGCAATTCGTCCAGGGAGGAAGTCTATATTATCACCTGAAGCACGTGCACGACGGCGTAAAGAATCACACCTGCGACATATGCGGCCGCAGCTTCGCTATGAAGACTGCCATGGAGGACCATCGGCGTATCCATACCGGTGAACGCCCATACGTGTGCCACACTTGTGGCAAGACTTTCAAGACCAAGGCGTCGCTCTACATACACAGCAAGACCCATACGGACGAGTTCCCGCACAAGTGCACCTATTGTGCCAAGAGGTTCCGCTGGAGACAGCAGATGCTGGGTCACTTGACGGTGCATACAGGTGAGAAGAATCACACGTGCGATGTATGTGGCAAGGGTTTTGGTGTGAAGAACGACCTGACCAGGCACAAACGCGTCCACTCCGAGGAGAAGCCGTACACGTGCCAGCAATGCGGCATCAGCTTCGGCCAGAAACGTTATCTCAAAAGTCACGAACGCTTAAAGTTAGGAACTTGCGGGTACTCGCAAAGTTCAAGTCGAATTGAATCCGATTAA
Protein Sequence
MSSKKSSTHLGDLDKRLEKDYSADSHADNSEQTQKPQEKHTVDSRGCIEQSEQHDELTHSKTTEGNGYASHKCGECGKVLSTSYNLLIHRNIHAGVRPYICPVCDKSFRSASGLNRHVRDVHDGVKNFACDVCGRHLASRASRDEHRRTHSSERPHVCETCGKSFKQKASLHVHRLYHSQVLPHRCDLCDRGFRRKQELDKHASWHSDRKPHACDICNERFRSKGCVARHRRTHTDQRSHVCTICGARFTQERYLKRHCGSLHPAVHTLKNHTVTHDRIMAHSYFRQEYKVGERRSKINPIQTKMSNIIDGGSENISFTDNTRNDKSTERLSPTNTSPKVFSSDKLTNDKRKTNIEDKGSNPASQTQASCTKRTKAMRYTRQEPAAEVNESNEYLEKNVKQSKSKKAACTSLAMVCKFCNKKFRSRKSYWAHVRMHSGEKSYTCHICGKQFVQGGSLYYHLKHVHDGVKNHTCDICGRSFAMKTAMEDHRRIHTGERPYVCHTCGKTFKTKASLYIHSKTHTDEFPHKCTYCAKRFRWRQQMLGHLTVHTGEKNHTCDVCGKGFGVKNDLTRHKRVHSEEKPYTCQQCGISFGQKRYLKSHERLKLGTCGYSQSSSRIESD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00129182;
80% Identity
-