Ader000231.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anticlea derivata
Gene Symbol
-
Assembly
GCA_947579855.1
Location
OX388280.1:3442835-3464670[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.3e-13 1.1e-09 37.9 0.0 8 70 231 291 226 296 0.87

Sequence Information

Coding Sequence
ATGTCGGAGGAAATGGCGGTTTCTAATAGCGCGACAGGGGAAGATGCCACCGTACAGGCCGGTGCCACGGTGGAAACTGTGGCTGAGGCGGCCGTAGCGCCTCCGGAGCAGCCGATTGAAGTTCCAGTCGAGCATCCAGAACCACCTCCAGCAGTCCCAGATGAGACCTCACAACCAGATCCTGTCAAATTAGAACCGGATCCGGAACCAGAACCAGATGTGATGCAAGCTTCTAAAGAAACAGAAGCTCCAGTCAAAGATGAAGTGGAAGAGACTGAAGTTCCACTTTTAATGGACATCAAAGATGAGTTTGAGGCGACAGACAACATGGAGTATCAGAACGAAGATGATAAGAGAGGCATCAAACGCAGGGCGTCGGATGCCTTTGATGATGACGTGGAATTTAAAGGTTTTGAGAAGATTGAGGACTTTCCTCAGTTAGAGTACAGCCTTATATTGGAGCGTCTGGAAGCCGAGGTGAAAGCAGCCTGCAAGGGCTTTACACCCGTGAGGACCGTGATGGCTACCCCCTCCGCTCCCGCGCGCGCCAGCAAACGACCCCGCAAGGATACTGATGGATCAAGACCTTCATCAGCACTGTCCTCAAGATCTGAAGATGATGTGAACCCGTCCGCGTCGCCGGCGCAGCGCGGTCGGCGCACCGCCAGCGAGATGTCCTCGTCCCTGTTCCGCGTGCCCATCGACCTCGGCTGGAAGAGGGAGCTGGTGTACCGCGCCGCGTTGGACGCCCACTCGCGCCGTAACGCCGACATCTACTATTACACGCCCCATGGGAAGAAACTAAGGTCTATGCGAGAGGTTGGCGAGCATTTATCCGGCACCGGCCTGACATTAGACAACTTCACCTTCTTCAAGGAACCGCTGGGCCTCGACGATCCGGAAAAAGAAATTATCAGAGACGCAAAGTTGGTAGGCGGCTATCGTCGCGTGGAATCCCCGATAGCGTCCCCCGCGCCGGTCATCGACGGCAAACGAACGCCAAAGCCGAAGCAGCCCAAAGGCGCCAGTCCCGAACCTGCAACACCGAAATCACCGCCTGCTAAGCTGAAGGTGAAGTCAGTGGGCTCCCGACTCTCCGGCCCAGCCCCCGCCCCCGCTAAGAAGAAGCCTTCCCCCGCGCCTGCGTCCCCCGCCCCCGCCCCCGCCCCCGCGCCCACCACGCCTGACAACAACAACACTGCCGCCTGGAAGAAACCCAGGGCGCCGCAGACCGCGCCCCCCGCCCCCCTCGCGACGGAGGAGGCTCCGCCCCCTCCAGCCCCGGTAGTCCCAGCCCCGGTGACCCAAGCCCCGATACCGAGGCTGGTAACGCCACCGCCGCCGCCGCCGCCGCTCCAGTCGAAGCCGACGTCGCAGATGATGTCGCCTAATGCACTACAGTCCCCGCGGCAACTGGTCCAGCCATGTTCGATGTCTTGCGGCGCCGGAGTTCCTTCACTATCCTGCAGCGCCTGTCTCTGCCTGTACCACCCGGCCTGCGCTGGCTTCAAGCAGACCCCGCCCCCCGCCACCTTCTTATGCAAGAACTGCCGCAAATCGTCTTCACCCCCGCATGATCCGCCGCCGCTCACGCACAAGTCGGGGGTGACGGCGTCCGGCGCGACGCCCGCGGTGGCGGTCCCGACGCCGCGGAGACTGCCGCCGCCTCAGGGCAACGCGCACAAACCTAACGACAAACGTGTACTGCTCAGAATGAAGGTGTCAGGCGGTGGCGCAGACGGCGAGCGCGTCTGGGCAGTGGCCCAGCCCCGCCCCGCGGGCGCCCCTCGCCCTCCCGCCCCCGCGGCCGCGCCCCCCGCCCCCACACCCCGTCTGCTGGCCATTAGAGGGGGGCTGCCACAATCGCTGGCGATCATCAACGGCCGCCGGTTCATTATAGTGCCGCGGCCCGCGCCATTGCCTAACGCAACCACGACGCAGGCGCAAGCTACACACGCAGCGGCCAACGAGGACAAGCGGCGGACGCGCGTGACGAACGGCGCCCCGACGCCGCCGATGGCGGCCGTGTCGCCGCGCCGCCGGGGCAGGCCAAGGGCCGACGCCAAAGACGAAATAGACCACTTCTCCGCTTTCTACGAGCGAGCCAAAGAAAGCAACGTTGTTGTGCAGATATTCCAGTACCTAGGTATGAGGGATTTGGCGCATTGCGCGCGCGTCTGTCGAGTGTGGAAGGAGCTGTCAGCGACGCCCGCCTTATGGAGACACGTTAGGATGAAAAACTCGCAAGTAAACGACTGGGGAGGGCTATGCGGCGCCCTCAAACGACACGGCACAAAGTGGCTGGACCTACGCAAGATGCTACTACCACAGAACGATATCGCATTCTGGGACCAGTTCGCACAGCACATAGCCAAAGTCGACTCGCTAGAAAGGTTGGAAATGTGCCGGTGTCCAGCTCGAGCAGTAGAATCGGCCAGTGCCTCGCTACCAGCGCTTCGATCCCTGTCCGCGCTCGCTATCAGAGATGCCATGCTTGACCCCACTCCGCTGGCTAAGGCAACGGAACTCCGGGAGCTTCGTCTGAAGAGTATGCAGGGCTTAGCGCTTATAGCTGATCTGACTCCACTAGCCAATCTGAAGCATCTAAAACACCTATCGCTCACCTCTATCAAGGAGCTGGGGTGGCGCGCGTGCGACGTGGTGGGCTCGCTGTCGCAGCTGGAGTCGCTGGAGCTGGGCGAGTGCACCTTCCGCGAGGAGTTCGGGTCGGTGCTGGCGCGGCTGGGCCGCCTCGTGCGCCTGCGCCTCGAGCGCGGCACCGCGCACTGCGCCGCGCCCGCGCTGCTGCGCGCGCTCGCGCGCCTGCCCAACCTCACCAGCCTCGAGCTCGTCAACATCGACGTCAAGGTTGGTTTCGACGACGCGCTCGCGGAATGCAAAAATATTCGGAGACTACTCATCATACCTACATACGTGTCACAATCAGCAACCACGAATAAACAGGTGCTAAGCGGCGTCCTCCGACTAAAGGACACACTGACTCACCTAATGTGGGGCGTCACGATCGAGCTGCTGCGCGTGACGGAGCTGTTCATAGACCAGTGCTCGGCGGGCGGCGGCGGCGGGCAGGCCAAGCGCGAGCTGGGCGAGTGCATCCCCGTGCTGAAGCCCGTGCCCGGCTGCAGGCTGCCCATGGACCACCAGCTCGTGGCCGGACCTCCTCAGGTTGAAATCCTCCCCCTCCCCACACTACAGCGGCTGCTCTCGGCTCAACTCCCCAACACTAAGCTGAAACTCCTGCGCATCCCTTTCCACGCGACATGGCGGCAGTCGCTCGCGGACTTCCAATAA
Protein Sequence
MSEEMAVSNSATGEDATVQAGATVETVAEAAVAPPEQPIEVPVEHPEPPPAVPDETSQPDPVKLEPDPEPEPDVMQASKETEAPVKDEVEETEVPLLMDIKDEFEATDNMEYQNEDDKRGIKRRASDAFDDDVEFKGFEKIEDFPQLEYSLILERLEAEVKAACKGFTPVRTVMATPSAPARASKRPRKDTDGSRPSSALSSRSEDDVNPSASPAQRGRRTASEMSSSLFRVPIDLGWKRELVYRAALDAHSRRNADIYYYTPHGKKLRSMREVGEHLSGTGLTLDNFTFFKEPLGLDDPEKEIIRDAKLVGGYRRVESPIASPAPVIDGKRTPKPKQPKGASPEPATPKSPPAKLKVKSVGSRLSGPAPAPAKKKPSPAPASPAPAPAPAPTTPDNNNTAAWKKPRAPQTAPPAPLATEEAPPPPAPVVPAPVTQAPIPRLVTPPPPPPPLQSKPTSQMMSPNALQSPRQLVQPCSMSCGAGVPSLSCSACLCLYHPACAGFKQTPPPATFLCKNCRKSSSPPHDPPPLTHKSGVTASGATPAVAVPTPRRLPPPQGNAHKPNDKRVLLRMKVSGGGADGERVWAVAQPRPAGAPRPPAPAAAPPAPTPRLLAIRGGLPQSLAIINGRRFIIVPRPAPLPNATTTQAQATHAAANEDKRRTRVTNGAPTPPMAAVSPRRRGRPRADAKDEIDHFSAFYERAKESNVVVQIFQYLGMRDLAHCARVCRVWKELSATPALWRHVRMKNSQVNDWGGLCGALKRHGTKWLDLRKMLLPQNDIAFWDQFAQHIAKVDSLERLEMCRCPARAVESASASLPALRSLSALAIRDAMLDPTPLAKATELRELRLKSMQGLALIADLTPLANLKHLKHLSLTSIKELGWRACDVVGSLSQLESLELGECTFREEFGSVLARLGRLVRLRLERGTAHCAAPALLRALARLPNLTSLELVNIDVKVGFDDALAECKNIRRLLIIPTYVSQSATTNKQVLSGVLRLKDTLTHLMWGVTIELLRVTELFIDQCSAGGGGGQAKRELGECIPVLKPVPGCRLPMDHQLVAGPPQVEILPLPTLQRLLSAQLPNTKLKLLRIPFHATWRQSLADFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00632776; iTF_00638666; iTF_00811050; iTF_00361647; iTF_01219794; iTF_00661302; iTF_00662244; iTF_01529213; iTF_00267205; iTF_01335957; iTF_00686366;
90% Identity
-
80% Identity
-