Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.014 2.4e+02 4.2 0.1 23 46 24 47 19 53 0.86

2 8 1.3 2.3e+04 -2.2 0.0 25 44 66 85 48 90 0.63

3 8 1.9e-05 0.33 13.3 0.0 13 47 90 124 82 129 0.84

4 8 0.00055 9.7 8.6 0.0 21 48 126 152 122 156 0.88

5 8 0.44 7.7e+03 -0.7 0.0 23 46 184 207 177 215 0.77

6 8 0.2 3.6e+03 0.4 0.1 21 44 210 233 198 237 0.81

7 8 0.00087 15 8.0 0.1 20 48 237 265 230 269 0.83

8 8 0.013 2.3e+02 4.2 0.2 21 44 266 289 264 296 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.014	2.4e+02	4.2	0.1	23	46	24	47	19	53	0.86
2	8	1.3	2.3e+04	-2.2	0.0	25	44	66	85	48	90	0.63
3	8	1.9e-05	0.33	13.3	0.0	13	47	90	124	82	129	0.84
4	8	0.00055	9.7	8.6	0.0	21	48	126	152	122	156	0.88
5	8	0.44	7.7e+03	-0.7	0.0	23	46	184	207	177	215	0.77
6	8	0.2	3.6e+03	0.4	0.1	21	44	210	233	198	237	0.81
7	8	0.00087	15	8.0	0.1	20	48	237	265	230	269	0.83
8	8	0.013	2.3e+02	4.2	0.2	21	44	266	289	264	296	0.90

Coding Sequence: ATGGTACCAAGCAAAACTGTGAAAAAACAGTTCAGCAATAATCATGTAACATTAATGGAAAGTAAAAGTCAAAAGTTCTCATGTCCACACTGTCACATGGCTTACTCAAAAAAGGGTAACTTAGACAACCACATAGAGTGCCACAAAAGATCAAATACCTTATCACAAGAACCTGCAGATGCAAGTGACGGAGAATTTGCTTGTGACCACTGCAACAAAGtgtttaaatctaaaaaacatATTCTGGCACATCTAAGTAGGGTTAGTGAGAGGAAAAAGGCACATTTTGGTTCCAGAAAACCTCATATTTGTGATATTTGTTTTAAAGCTTTTAACCAAATCTCAAACCTAAAAGACCACTTGCGCACCCACAACGGAGAAAAACCATTTCTCTGTCCCACTTGTGGTAAAGGGTTCAACCAATTGGGAAACTTACGACAGCATCAAGTGCGCCACAGCGGGGTAAAATCGCACATTTGCTCCACCTGTAACCACGGTTTCGCCAGTAAGGGCGAACTAGACGCCCATTTAAGAAAACACACAGGGGCGCGTCCGTTTGTATGTGATGTTTGCGGAAACGGGTTCACCACCTCCTCCTCACTAACCAAACACAAACGTATCCATTCGGGCGAAAAACCGTACGAGTGCGACTATTGCAAAATGAAATTTTCTCGGTCCGGGATTTTGAGTCGACATCGCCGTATACACACCGGAGAGAAACCGTACGTGTGCGAAGTATGCAAAAAGGCGTTCACGCAATCGAACGATCTGAATTCGCACGTGCGAATTCATACGGGTGAAAAGCCGTACGCGTGCGATAAGTGCGGTCAACGGTTTAGGCAAAATTCCGCTTTGAGGACACACAGAAAGACACATTCGCAAGAGCCCAGATGTAGGAAGGAACGACAACCGCGACCTCCTCTTTTCGTCGAGGAGGAGGAGAATATTTTGATGGTCAACTTTGAGGAGGGAATCGCGCCTCATTCAGTATTTGCTGCCATGtaa
Protein Sequence: MVPSKTVKKQFSNNHVTLMESKSQKFSCPHCHMAYSKKGNLDNHIECHKRSNTLSQEPADASDGEFACDHCNKVFKSKKHILAHLSRVSERKKAHFGSRKPHICDICFKAFNQISNLKDHLRTHNGEKPFLCPTCGKGFNQLGNLRQHQVRHSGVKSHICSTCNHGFASKGELDAHLRKHTGARPFVCDVCGNGFTTSSSLTKHKRIHSGEKPYECDYCKMKFSRSGILSRHRRIHTGEKPYVCEVCKKAFTQSNDLNSHVRIHTGEKPYACDKCGQRFRQNSALRTHRKTHSQEPRCRKERQPRPPLFVEEEENILMVNFEEGIAPHSVFAAM

Sequence clustering based on sequence similarity using MMseqs2