Aper018279.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Antheraea pernyi
Gene Symbol
ZFHX3
Assembly
None
Location
GWHABGR00000032:11006927-11019839[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.12 7.6 7.4 0.2 2 23 93 115 92 115 0.94
2 16 0.00022 0.014 16.0 1.8 2 23 309 331 308 331 0.95
3 16 5.4e-05 0.0035 17.9 0.7 1 23 363 387 363 387 0.92
4 16 0.008 0.52 11.1 0.4 1 22 435 456 435 459 0.91
5 16 6.3 4.1e+02 2.0 0.3 1 23 633 657 633 657 0.88
6 16 0.036 2.4 9.0 2.0 1 23 755 778 755 778 0.94
7 16 0.0097 0.63 10.8 0.0 1 23 785 808 785 808 0.95
8 16 0.04 2.6 8.9 3.7 2 22 862 882 862 885 0.90
9 16 0.017 1.1 10.0 1.0 1 23 897 922 897 922 0.94
10 16 0.0098 0.64 10.8 1.3 1 23 940 962 940 962 0.97
11 16 0.0011 0.07 13.8 0.2 2 23 969 991 968 991 0.96
12 16 0.00021 0.014 16.0 3.1 1 23 1097 1121 1097 1121 0.92
13 16 0.0087 0.57 11.0 0.7 1 22 1141 1162 1141 1165 0.89
14 16 0.00021 0.014 16.1 0.2 1 23 1212 1236 1212 1236 0.93
15 16 1.9 1.2e+02 3.6 0.0 3 21 1311 1329 1310 1330 0.91
16 16 0.64 42 5.1 3.5 2 19 1420 1437 1419 1442 0.91

Sequence Information

Coding Sequence
ATGTTGAAAGATTCGATGGCAAGATTCCGAGAGAGTAACGTTGTCGAAAAGCATCTGGAATTTCCTCAAATAGCCAGTGCATTTTATGTATCAAGAAACCCTTCGTTGTATGGTGCATTATATGGTAGATTAGCAGCAGAGAGAGCACGAGCGAGGCCTGATGCGCCTGTTATGCACAGTTATCGAGTTTTTAGCTTTAGAGGAGGAAAAGACGCTCCAAGGCCTGCATCTCCATCTGCTGAATGTCCAGTCAGTGTTCCGGTTAAACCCATTCTCATGTGCTTTATATGTAAATTGAGTTTCGGCTACGCAAAGTCTTTCGTGGCACATGCCCAATCAGATCACAGTTTATCGTTACTCGAATCAGAACGAGACGCTTTATCAAGGGAAAATGCGTCAGCTATAATCCAGTGTGTTGGAAAAGACAAAGAAGCATTAGTCTCGTTTCTAGAGCCTGTAGGAGCTGCAGCCCCACCGCGCCATTCAACATCTGGTAGCCCAGCAAATATGTCAGAGCTCTCAAGCCCTTCTATAGATAAGAGGTTAGATTTGACAACTCCAGACCGAGAAAGTGAATCAATGTTACCAAACGGCATTTGTGATGACAGAAGGCCGAGCCCGACTACGTGGAGACCTCCAAGATCAATAGCAGAGTCTCTGGTACCTCAACATTCCTTGATCTCTGTAGCTCATCCTCATACAATAAATGCATCGATACAGCCTCGGTCCAGTCCAAATTCTTCTCCACCATTTCAAGCTGCCCCACCGGCTTTCTTGTCAGGTACAACGATAGGTGTATGTCCAGATCACCTAGGTGGAAGACCTTCTGGTGCCGATTGTCCTAAATGTGAACTTATTTTGAATTCAGGACGACTAGGCGGTCCGCTGGCCGGAATGCATAGTCGAAATTCCTGCAAAACCTTAAAATGTCCAAAGTGTAACTGGCATTACAAATATCAGGAAACTTTAGAAATACATATGAAAGAAAAGCACCCCGAAGCGGAGACAAGCTGTATATACTGTATAGCTGGACAGCCTCATCCTCGATTAGCACGTGGAGAAACTTATACTTGCGGGTACAAGCCTTACCGTTGCGAAGTTTGTAACTATTCAACTACAACGAAAGGCAACCTCAGTATACATATGCAGTCTGACAAGCATTTAAACAATATGCAAGAATTACAGAATGGAGGCAATCCAGGAGAAGGAAATCTTCCTCCTGCACCTCAACATACTCCTCCCGGCAATCATAAGCCTCCTTTGCCACACCATTCACCTTTAGGTCAAAAGCCAAAGCCGACCTTTCGCTGCGACGTCTGTAATTATGAAACCAACGTTGCGAGAAATCTAAGAATACATATGACATCTGAGAAACATACGCATAATATGTTAGTTTTACAACAAAACGTGAAGCATATGCAAACATTATCAGCGTTACATCACAGACAACAAAACCAACAACAACTTGAAAGTTTATTACACTTTCATGGTGGGGATCCGCTACCTACTAACCCAGAAGCAGCTCTTGCTGACATGGCCTACAATCAAGCATTAATGATTCAACTTATGACCGGTGGCCCAGGGCCTTCTCCGCCTGAATTAGGTGCCCATCTCGATGTTGGTCTAAATCCTGAAGCAATGGAACCGCCCCCAGAACCTGCGGATCCTGAACCAGAAAGGACATTCCATTTGGAAATTGAAGTTTTGTGGTGGTGTAGGAACAGGTGGTGCGGTGTTGGTGGTGTCCAAGTACGATGCTGCGCTTGCGATTACTACACCAATTCTGCTCATAAGCTACAACTTCATGCAGCAGGTGCGAGACATGAAGCTGCAACATTACTGTTGAGACATCTTAGAGATTGTGCATCACGAATAGTACGGGAACGTCCCCGCGTGTACCGTTGCGCTCTTTGCGGCTTCAATGCTCCCCATCGCCTACCTCTTCTGCAACACGTACGATCTGTGAAACATCTACAAATGGAACAAATTCACCAGCTTCAACGGCGATCAGAAGGCAAGGACCCAACTCCCGACGTAGCCGAACTTTTCCAGGTTATACCTCAGCCACCAGAATTGCCAAGTCCCTACGAACAACAAGATAACGATAACAAAGAACCAATCGATCAGAAGCCAGAATTGACACAAGAACAGAAAATGATGAGGTTTTTGGAACAACACCAACATCAGCAACAGCAGCATGCACAACAACAACCGCAACAAAGTTCCAACGAAAGAGAAGACGAGCGCGACACACCTGGACAGCACACCTGTCCATACTGTAACTTTAGTACCTCAAATGAGGCACGTCTTCATGCACATGTTACCTCAGTACACAGTGAGTCTGCGCGTCATTTCATTTGTCCGCTGTGCCAAGATGCATTTAAAGATCGACCGGCTCTTGAAAGACACGTCATGCAAATTCATTCCGTAAACTCCGAAGGCTTGCAGAGGTTGTTATTGCTCGTAGACCAAAGCCATTGGCTGAACGGTGGAGTTCAACAGAGAGACGAATCACGGCAAGTTGACGACGAACGTGAGATCTCATCACCACGTTCAGAGGGCAGTGCCGATGGTGAAACCGAACGATGCTTAACCTGCAGTCGTACATTTCGCAACGTCGATGAACTCTGTCACCATCAGAATGAGTCTGGACATCTAGAATTAAAACAGACTCCTCAAGGCCCTGGGTATGTTTGCTGGAAGAAAGGATGTAATAGATACTTTGATTCAGCACATGCTTTACAGAATCATTTCAGGGAGGCACATGCTCGCAATTCGATAGCAAATATGTCTGTATCAGAAAAACATGTCTACAAGTACCGATGCAACCAGTGCAGTCTTGCGTTTAAAACTATAGAAAAATTACAACTACATTCACAATATCACGTGATTCGTGATGCAACAAAGTGTGTGCTCTGTGGTAGAAGTTTCAGATCAGTACTTGCACTGCAGAAACATGTAGAAACAGCTCACTCGGAATTATCTGAAGAAGATTTAGCAGCATTCAAACGTAGTTTGGCATCCAATCCATTGATGCAATCTGGTCAAGGAACAGCTCTTGATGCTGCTACAGCTGAGCTTTTACGAAAAGAAGCTCTAAGAACACCAGATGATGACATGGCAGACCTTGAAGACCGTGACTCCAGTGCTACAGTTGCTGACGAGTCTGGCCATAATGATGCCGAAAACTCTGATGATTCGATTATTTATAAAGATCAACAGTTCTTAGAAGATTATTTAAACTCGCAAGCTATGGCCGAAGATTCATATAATGACCCAAACCGAAAATATAAATGTCATCGATGCAAAGTAGCTTTCACGCGACAATCATATTTGACCGCTCATAATAAAACACTGCTACATAGAAAAGGTGAAAAATTAACGTACCCTATGGAGAAATATCTAGATCCCAACAGGCCATTTAAATGTGACGTATGCAAAGAATCGTTTACGCAAAAGAATATACTTCTTGTACACTATAATAGTGTAAGCCATTTGCATAAACTTAAACGAGCTATGCAAGAACAACAAAACAATAACAACCCTCCCGTATCACCCGGAGCGGGTTCCGCACCTTCCAACTTGACGCTTACTCCTAAAAGTACTTCGAGCGAGGAAGATGACCGTAAACGTTATAAGTGTAATATATGCAAAGTCGCCTATACGCAGGGTAGTAACCTCGATATACACATGAGATCCGTTTTGCATCAAACCCGAGCTGGCAAGCTGCAGGAACTCGCCGCAGCCGGGCAAGTGGATTTGACACGACCTTTAGTCGAACAACCGGACAGAAAGGATCCTGCTAAAATTTTACAAGACGTTTTGTCGCCAAAAAATACATCCCCTTCGTCAACTAGCAGTGGGGGACCGCGTTCCTCACCCCCCGTACGGCCAGGTAGTCCCCGATCCCCTCGCTCAGGTAGCGCCGCGTGCGATCGATGCCACGCGTCATTTCCTACCGGGGAGCTACTCGACGCACATCGCGCGACCACATGCCCGTTTAGCGATGCGCGGGCGCATTCGCCGCTAGGTGAAGCCGAGGCCGCGGCAATAGACGAAATGGTCGCGAAGGGTAATCCGCCTAAAAAAAACTCGCAAATGTATAAACAACTTTTAGAGACCTTCGGCTTCGACCTCGTCATGCAATACAATGAAAACCAACGGCGAAAACTTCAAGAAGAACGCGAGATAGCGCGCGCCCCGAGTCCTCCACCGCCACCGCCTGAAGAAAAGCCGCCTGACGGTGAAACGAAATCCACGTGTCAACACTGTAACAAGGAGTTTTCTAGTGTATTCGTATTAAAAACACATTGTGAAGAAGTGCACAAAGACAAAGTTCCGTTAGAATTTTTGGAGCAGTTCGCGGAGCATTTCAAGTCTGAATACGAGAGAAAATCGGGAGCACCAAATTCACCGCGAGCTGCGTCACCCGCGCCTCATGATGAGAGGTCGCCGTCTCCTCGCGGGGATAGTAACGCAGCCTTCAATGAGAACGGGAACACGAGTGGCGAGGCGCAAGCTGGCGCCTTGCTTGCAGCTCAGGTACAAGAGATGCAGGCAGCTTTGAACATGATACAGTTGCAGCAGCAGCTCGGTACTATACATCCGATGGTTGCACAAATGTTATCGCTTGGTTTACCACTTGGATTAAATGTGGGCGCACTGGCAGCTATGAACCTCCAGCCACCCTTAGTGCCATTGATGATGCCGCCACCACCTTTCGACGCGATGTCCTTCGCTCACGACGCGCAGCTCAAACAACAACAACTGATACAGCAACAGCAGCAGGCTAACGCTGCAGCTGGACAGAAACGAGCTCGCACGCGTATAACTGACGAACAACTCAAAATTTTACGAGCACACTTTGATATAAATAACTCTCCGAGCGATGAAGCTATCGCTAAAATGGCGCAACAATCTGGATTAGCTACCAAGGTAATAAAACATTGGTTCAGAAACACACTATTCAAAGAACGTCAACGCAACAAAGATTCTCCATACAACTTTAACAATCCTCCATCAACGACGCTCAATCTTGAAGAATATGAAAAAACAGGTGAGGCTAAAGTTACACCATTAGATTCATCTATGAGCTCCGATGAAGGCAAGCCACCACCAGAAAAAAAAGCAAAAATTGAAGACTTGTCAATTATCAGTCACCCAGAAGTGAAATCAGAACCTAACGATGAACCGACCATGGAAGAAAAATATAATTCTCTACGACGACAGACATCAAGAAGACAAAAGTTTCCTTTTTCCTCAAGCGCCTCCTCAAAGCCCGGCTTTGAGTCACCCTGA
Protein Sequence
MLKDSMARFRESNVVEKHLEFPQIASAFYVSRNPSLYGALYGRLAAERARARPDAPVMHSYRVFSFRGGKDAPRPASPSAECPVSVPVKPILMCFICKLSFGYAKSFVAHAQSDHSLSLLESERDALSRENASAIIQCVGKDKEALVSFLEPVGAAAPPRHSTSGSPANMSELSSPSIDKRLDLTTPDRESESMLPNGICDDRRPSPTTWRPPRSIAESLVPQHSLISVAHPHTINASIQPRSSPNSSPPFQAAPPAFLSGTTIGVCPDHLGGRPSGADCPKCELILNSGRLGGPLAGMHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGNPGEGNLPPAPQHTPPGNHKPPLPHHSPLGQKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHRQQNQQQLESLLHFHGGDPLPTNPEAALADMAYNQALMIQLMTGGPGPSPPELGAHLDVGLNPEAMEPPPEPADPEPERTFHLEIEVLWWCRNRWCGVGGVQVRCCACDYYTNSAHKLQLHAAGARHEAATLLLRHLRDCASRIVRERPRVYRCALCGFNAPHRLPLLQHVRSVKHLQMEQIHQLQRRSEGKDPTPDVAELFQVIPQPPELPSPYEQQDNDNKEPIDQKPELTQEQKMMRFLEQHQHQQQQHAQQQPQQSSNEREDERDTPGQHTCPYCNFSTSNEARLHAHVTSVHSESARHFICPLCQDAFKDRPALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGVQQRDESRQVDDEREISSPRSEGSADGETERCLTCSRTFRNVDELCHHQNESGHLELKQTPQGPGYVCWKKGCNRYFDSAHALQNHFREAHARNSIANMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVETAHSELSEEDLAAFKRSLASNPLMQSGQGTALDAATAELLRKEALRTPDDDMADLEDRDSSATVADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGSAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSNLDIHMRSVLHQTRAGKLQELAAAGQVDLTRPLVEQPDRKDPAKILQDVLSPKNTSPSSTSSGGPRSSPPVRPGSPRSPRSGSAACDRCHASFPTGELLDAHRATTCPFSDARAHSPLGEAEAAAIDEMVAKGNPPKKNSQMYKQLLETFGFDLVMQYNENQRRKLQEEREIARAPSPPPPPPEEKPPDGETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEHFKSEYERKSGAPNSPRAASPAPHDERSPSPRGDSNAAFNENGNTSGEAQAGALLAAQVQEMQAALNMIQLQQQLGTIHPMVAQMLSLGLPLGLNVGALAAMNLQPPLVPLMMPPPPFDAMSFAHDAQLKQQQLIQQQQQANAAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAQQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSMSSDEGKPPPEKKAKIEDLSIISHPEVKSEPNDEPTMEEKYNSLRRQTSRRQKFPFSSSASSKPGFESP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00776929;
90% Identity
iTF_00113221;
80% Identity
iTF_00113221;