Basic Information

Gene Symbol
-
Assembly
GCA_031304115.1
Location
JAPWJP010001192.1:3769730-3772561[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 2.8 5.1e+02 2.7 0.3 2 19 125 141 124 144 0.74
2 14 0.00052 0.094 14.5 1.4 2 20 151 169 150 172 0.94
3 14 0.00032 0.058 15.1 1.2 1 23 178 201 178 201 0.93
4 14 1.4e-05 0.0026 19.4 1.5 1 23 207 229 207 229 0.98
5 14 2.9e-06 0.00053 21.6 0.8 1 23 386 408 386 408 0.98
6 14 0.00035 0.064 15.0 0.3 2 21 418 437 417 438 0.93
7 14 0.00035 0.063 15.0 2.6 1 20 460 479 460 482 0.92
8 14 0.0078 1.4 10.8 0.1 1 23 487 510 487 510 0.96
9 14 1.5e-06 0.00026 22.5 0.3 1 23 516 538 516 538 0.98
10 14 0.00017 0.03 16.0 2.2 1 23 545 567 545 567 0.99
11 14 0.00041 0.074 14.8 0.4 3 23 575 595 573 595 0.97
12 14 0.00047 0.085 14.6 0.2 1 23 601 624 601 624 0.96
13 14 0.57 1e+02 4.9 0.1 1 23 638 660 638 660 0.93
14 14 4.1e-06 0.00075 21.1 0.2 1 23 920 942 920 942 0.98

Sequence Information

Coding Sequence
ATGGAAACTCACGAGAGTGAACAATATGTAACGTTTCCTCTCGACGGTGTGCACGATGCCATACAAGAGAATATGATATCTCATGAGGAGATATGCGAACCTGTCGAATGCGTTGACGAATGCGTCCTTCAGGAAGAGCTTACGGAAGTCTCAGTCAATAATACTAACAATACTGATATTGCTGAGTCGCAAGATGCTGTTGAAATTCTTACAGAACAGTCGGAGGAAGAGGATGACAATCAGGTGGTGTATCCGATGTACATCAAGCAAGAGGAGCCACAGCAGTATACGTCAGGTGACGACGAGTCCATGGCTGTGGAAGCCCTGCGTCAACTCGGCGGTATGTATCCATGCATTGAAAACAAGAAAATGAGCTGTCCAATTTGTAAGTGTCTCTTTACACAAGAAGAGATGGTTGAACATCGGTCTGTATGTACAGTATCTAAGCTATCATGCACTACTTGCGGAGAGAGATTTGAGAGAAAGATCGATCTGAATAATCATATGGTATGTCATCAGGTGGATCGTCCTCATGCATGTAGAACATGTGGCAATTTGTTTCGTTCTAAAAGCAGTCTGCAAGCACACATGCTGCAGGTGCATCAAGTCGAACGTCCACATAAATGTACCATTTGTGGCTCGGATTTTCAGAGACCCTCCAGCTTATCTAACCACATgaagatacatacatatgttgcAGGACGTGCAATCATGCAGACACAAGGGAATAATATGTCTCAATCAATGGAAACGTTTAGGAAGTGGCCGGAGAATGCCTCTGATTCGCAAAATACATCTCAGATGCCATCTTCTTCGTCTGCTCAATCTATACAGAATTATGATGTATGTCAAGTTCAATGGCCAGTCTCATCATACAATTTTCATAACGAACAATCGACAGTTACCACAATATCGAATCATCAGGAGAAGATGGATACACTGCAGGAATTCACGGTAATGCCTAATGGTGAGGTGACACAATTCAGCGAGTACACTGAGCAAAATAATATCAGCAGTCCAGTTAACAATAGTCAACAGTACGATATATCCATAAATTCGTTTAATACTCCCGACGGAATAGTCAAAGTCGAGACGCTTTCGTATAATAACgcaaacagaaaaaattatgctaaAGTCGAAACAAACAGTAAACAGTACACGTGCAAGCATTGTGGAATCACTTTTTCACGCGCAACTGCATTGGCATCTCATGAAAAGATTCACACTTCTAAAAATTGGAACGTACCGATTGAATGCGAATACTGCGACAAGCAGTTCCAAGATGCAAATCACTTGGCGACTCATCAGACTACCTGTGCCAAGAAGATAATGCAAAACAATATAGAGCAAGGCGTACCCAACAACAAGTGGGGCAAGCATGCTTGTTCCGAGTGTGGAAAGAAGTTTACGACCAAGCAGAAGATGTTTCGTCATCAATGGATCCATCGGAAGAAAACGTATTCGTGCGAAGTATGCGGTTCGCAGTTTGAGAAGCAAAACGAGTTGGATGAGCATAGATTGTCGGCGCATCCTGGAGATTCGCCGTTCACTTGCACTGAATGCGGAAAGAGCTTCGTGTCGCGTCAAGGTCTCTGGGAACACGGTAGAACGCACGCTGGGAGTCCGGCGCATTTTCAATGCGACACCTGTTCGAAAACCTTTTCATCTCGCCAAGGATATTTAATACACAATCGTACACATACCGGCGAACGACCGTACGGTTGCAAGTTTTGCTGGAAAGCGTTTCGGGATGGTGGAACCTTGAGAAAGCACGAACGGATCCACACCGGGGAGAGACCGCACGTGTGTCCGTTATGTTCGAGGGCTTTTAACCAGAAAGTGGTCTTGCGCGAGCACGTTCGATGGGTCCACGCCGCGGGAAAGAACGAGACAGAAGCGAGCAGTCCTCCGTATCCGTGCCCCCTGTGCGGTGCCCTGAATCAAGATCGCGATGAACTCTGCGCGCACATCGTTAAGCATTCGGATCAGATGATAGCCGAGGCAAAGGCAAAGACTAACAACGACGTCTCTCCAAAATCAAAGCCAACGAAGAAGAAATCATCGAAGTCAGCGTCTTCATGCAATGCACGGGCAAAACAAAATACTGCCTTGGAACATTTCATCTCCAAGGCGGAGCAAAATGAAGCCTTATTATCCATCACCGATACGTCTGATAAATCGGACGATTTGCACGTTATGAACGAGAAGCAGAATGCCTTCGTTGTGGTCACCACGGAAAAACGTAGCGACGGCTTCATAGCGATATCCGAGCTTAAACACAGCAACATACGATTTATTGTGGAAGGCAAAGAAGACGAGAACATTCACGTACTTCAAGTAGATCAGAATCATCGGGATCCTCTCGATATGATTGCTATAGATAAGCAAAATGATACGGCGCACATTGTGTCGACAGAATCCGTAGATAGTGCGCTTGATGAAACGATCAGACAAAACAACATATCCACGATGCACTTAATTCAATCTTCTAAACAGAacaatactttaaatataatatcgaagCAGAACGAATCGCTACCTGTTCTAGCAATACCGAATCCCCAGAGTCACGAAAATTACTCCAGCCAAATTATACAAGTGAGCAGCGCAGATATACCTATGGATGTAATAACTCAACAaactttaaaagaagaaatagatCAAGATGAACAAGATACTTTAGATACATCTCAAGAAGGGACATCTCATGTTATCCAAGTTGTACAGTATCAACATGACAGCGATGATGAAGAGGATTTTACTTGTGAGATCTGCGAAGAAACTTTtgctgataaaaatatgttgaaagAACATATTAAggttcatatataa
Protein Sequence
METHESEQYVTFPLDGVHDAIQENMISHEEICEPVECVDECVLQEELTEVSVNNTNNTDIAESQDAVEILTEQSEEEDDNQVVYPMYIKQEEPQQYTSGDDESMAVEALRQLGGMYPCIENKKMSCPICKCLFTQEEMVEHRSVCTVSKLSCTTCGERFERKIDLNNHMVCHQVDRPHACRTCGNLFRSKSSLQAHMLQVHQVERPHKCTICGSDFQRPSSLSNHMKIHTYVAGRAIMQTQGNNMSQSMETFRKWPENASDSQNTSQMPSSSSAQSIQNYDVCQVQWPVSSYNFHNEQSTVTTISNHQEKMDTLQEFTVMPNGEVTQFSEYTEQNNISSPVNNSQQYDISINSFNTPDGIVKVETLSYNNANRKNYAKVETNSKQYTCKHCGITFSRATALASHEKIHTSKNWNVPIECEYCDKQFQDANHLATHQTTCAKKIMQNNIEQGVPNNKWGKHACSECGKKFTTKQKMFRHQWIHRKKTYSCEVCGSQFEKQNELDEHRLSAHPGDSPFTCTECGKSFVSRQGLWEHGRTHAGSPAHFQCDTCSKTFSSRQGYLIHNRTHTGERPYGCKFCWKAFRDGGTLRKHERIHTGERPHVCPLCSRAFNQKVVLREHVRWVHAAGKNETEASSPPYPCPLCGALNQDRDELCAHIVKHSDQMIAEAKAKTNNDVSPKSKPTKKKSSKSASSCNARAKQNTALEHFISKAEQNEALLSITDTSDKSDDLHVMNEKQNAFVVVTTEKRSDGFIAISELKHSNIRFIVEGKEDENIHVLQVDQNHRDPLDMIAIDKQNDTAHIVSTESVDSALDETIRQNNISTMHLIQSSKQNNTLNIISKQNESLPVLAIPNPQSHENYSSQIIQVSSADIPMDVITQQTLKEEIDQDEQDTLDTSQEGTSHVIQVVQYQHDSDDEEDFTCEICEETFADKNMLKEHIKVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01476432;
90% Identity
iTF_00729521;
80% Identity
-