Basic Information

Insect: Anopheles ziemanni
Gene Symbol: -
Assembly: GCA_943734765.2
Location: OX030919.2:18140820-18142511[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.035 2.7 8.7 0.7 1 23 37 60 37 60 0.91

2 14 7.1e-06 0.00055 20.3 0.6 1 23 100 122 100 122 0.98

3 14 1.5 1.2e+02 3.6 2.0 1 23 145 168 145 168 0.89

4 14 1.1e-06 8.6e-05 22.9 0.2 1 23 208 230 208 230 0.97

5 14 0.014 1.1 10.0 2.2 1 23 236 259 236 259 0.94

6 14 0.00041 0.032 14.8 1.5 1 23 282 305 282 305 0.96

7 14 0.012 0.93 10.2 1.1 2 23 326 348 325 348 0.93

8 14 0.017 1.3 9.7 1.3 2 21 362 381 362 381 0.96

9 14 1.4e-06 0.00011 22.6 0.6 2 23 389 410 388 410 0.96

10 14 0.00057 0.044 14.3 1.3 1 23 416 439 416 439 0.96

11 14 0.0011 0.086 13.4 1.7 3 23 450 470 448 470 0.95

12 14 0.0047 0.36 11.5 2.3 5 23 479 497 476 497 0.96

13 14 0.19 15 6.4 2.7 1 23 501 523 501 523 0.98

14 14 0.0045 0.35 11.5 0.2 1 23 529 552 529 552 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.035	2.7	8.7	0.7	1	23	37	60	37	60	0.91
2	14	7.1e-06	0.00055	20.3	0.6	1	23	100	122	100	122	0.98
3	14	1.5	1.2e+02	3.6	2.0	1	23	145	168	145	168	0.89
4	14	1.1e-06	8.6e-05	22.9	0.2	1	23	208	230	208	230	0.97
5	14	0.014	1.1	10.0	2.2	1	23	236	259	236	259	0.94
6	14	0.00041	0.032	14.8	1.5	1	23	282	305	282	305	0.96
7	14	0.012	0.93	10.2	1.1	2	23	326	348	325	348	0.93
8	14	0.017	1.3	9.7	1.3	2	21	362	381	362	381	0.96
9	14	1.4e-06	0.00011	22.6	0.6	2	23	389	410	388	410	0.96
10	14	0.00057	0.044	14.3	1.3	1	23	416	439	416	439	0.96
11	14	0.0011	0.086	13.4	1.7	3	23	450	470	448	470	0.95
12	14	0.0047	0.36	11.5	2.3	5	23	479	497	476	497	0.96
13	14	0.19	15	6.4	2.7	1	23	501	523	501	523	0.98
14	14	0.0045	0.35	11.5	0.2	1	23	529	552	529	552	0.93

Sequence Information

Coding Sequence: ATGCAAACCAATCCAAGCATCGACGACAGTTACACCGAGGAATTGATCGACAATGGATCAACCGACGTAGGGTGTTACGTGGTGTCATCGGCACCGGATGATCTTAAATTCAGCTGCTGCGGATGTACCCTCTCCTTCGGGACCGAGAATGAATTGATGGAACATTCCGATTCGATACATGCACCAAATGCGCCCCCGCcacacaaaaccaaaccagtgCAGTGCAACGTTTGCTATAGCTGGTATTCATCCGAGCGGTCTTGCCGGGACCATCAGGTCTACATGGGCAACCGTCAGTTTATGTGTCCGGTGTGTGGTATGCGCTTTGGCCGAACTTCTTCGCTACTGCGACATAAAAGCACACACGATAAAATACCGGACGAGGTGGAAGCGAGTCAGGTTGTTGAACCCGAGCTACTGGATGATCTACAGTTTAGCTGCTGCGGATGTATGCTCTGCTTCGAAACCGAGAATGAATTGATGGAACATTCCGTTTCGGTTCATGCACCAAATGCGCCACCGGAAGACGACAACAAGCCAGTGCAGTGCAACGTTTGCTATAGCTGGTATTCATCCGAACGGTCGTGTCGGGATCATCAGGTCTACATGGGCAACCGTCGGTTTGCGTGTACGATATGTGGCCAGCGCTTCGGTCGTGCTTCGGCCCTCGTACGCCATCGAAATACGCACGAAAAGGCACTCATATTTTCGTGCAAATATTGTGGAAAACTGTTTCCCAGCACGTACAAAAAGTTGAGCCACGAAAAACGGGAGCATGAGAACCCGCTCGTAAAGGGTACCGATACTGAATCGGCCggcgaagaacaaaaaaaaccacttATCTTTTCGTGCAAATATtgtgaaaaaatgtttgccaaCGCGTACAGCAGGATGAGCCACGAAAAACGGGAGCATGAAAATCCGCCCGTAAAGGATGCCGAAGCCGACTCGACCGGTGAAGActcaaaaaagcaaacatgctGTGGATGCAGTGAAACCTTCGATAGCGAGCACGAATTGATGGTCCATGCCGGTACGGTGCACGCCCCGAATGCACCCCCCGACGACGACGCGAAACCGGCCCGATGTAACATCTGTTATCGATGCTACAAATCCGATTCCGCTGTACGGGTGCATCAACGGTGCATGCGCATGCGCTCGCTGCAGTGTGCGACCTGTGGCAAGAGCTTCGCAACACGATCGCATCTGCTCGCACACGAAAACGTTCACACCCAAGCGTTGATCTACGCGTGCGCCCATTGTGACGAAAAGTTCGCCAACAAAACGGCCAAACAGAAGCATATCGCACGAAAACACGGCCCGCCGGTGGCCCCCACCAAGCATCTTTGTCTCACCTGTGGTAAagcattcaattcaattttctaTCTGCGAGACCATCTGAAGCTGCACGCTGACGAGATGCCATACTCATGTCACTGCGGTGCTAAGTTTAAGCTGGAAAAATACCTCAAAAGGCATATGCAAATACACAGCGGGAAGTACACGTGTCAGTTTTGCACCCTCGCCTATCGTTGCGCGTCCATGCTGCGGGACCACGAAAACCGGCACACGGGGAATAAGGAATTTCCCTGTGACCTCTGCAGCAAACGGTTCTACGGAAAAGCGGACGTGGCAAAGCATCGTGCCTATGTGCACTTTAAACGAGGGAAACTACGTAAAGCTTCTTCCTGA
Protein Sequence: MQTNPSIDDSYTEELIDNGSTDVGCYVVSSAPDDLKFSCCGCTLSFGTENELMEHSDSIHAPNAPPPHKTKPVQCNVCYSWYSSERSCRDHQVYMGNRQFMCPVCGMRFGRTSSLLRHKSTHDKIPDEVEASQVVEPELLDDLQFSCCGCMLCFETENELMEHSVSVHAPNAPPEDDNKPVQCNVCYSWYSSERSCRDHQVYMGNRRFACTICGQRFGRASALVRHRNTHEKALIFSCKYCGKLFPSTYKKLSHEKREHENPLVKGTDTESAGEEQKKPLIFSCKYCEKMFANAYSRMSHEKREHENPPVKDAEADSTGEDSKKQTCCGCSETFDSEHELMVHAGTVHAPNAPPDDDAKPARCNICYRCYKSDSAVRVHQRCMRMRSLQCATCGKSFATRSHLLAHENVHTQALIYACAHCDEKFANKTAKQKHIARKHGPPVAPTKHLCLTCGKAFNSIFYLRDHLKLHADEMPYSCHCGAKFKLEKYLKRHMQIHSGKYTCQFCTLAYRCASMLRDHENRHTGNKEFPCDLCSKRFYGKADVAKHRAYVHFKRGKLRKASS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00096575;
90% Identity: iTF_00096575;
80% Identity: iTF_00096575;