Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:18140577-18142511[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1 80 4.1 2.3 1 22 21 42 21 45 0.88

2 15 0.041 3.2 8.5 0.7 1 23 118 141 118 141 0.91

3 15 8.3e-06 0.00065 20.1 0.6 1 23 181 203 181 203 0.98

4 15 1.8 1.4e+02 3.3 2.0 1 23 226 249 226 249 0.89

5 15 1.3e-06 0.0001 22.7 0.2 1 23 289 311 289 311 0.97

6 15 0.016 1.3 9.7 2.2 1 23 317 340 317 340 0.94

7 15 0.00048 0.038 14.6 1.5 1 23 363 386 363 386 0.96

8 15 0.014 1.1 10.0 1.1 2 23 407 429 406 429 0.93

9 15 0.02 1.6 9.5 1.3 2 21 443 462 443 462 0.96

10 15 1.6e-06 0.00013 22.4 0.6 2 23 470 491 469 491 0.96

11 15 0.00067 0.052 14.1 1.3 1 23 497 520 497 520 0.96

12 15 0.0013 0.1 13.2 1.7 3 23 531 551 529 551 0.95

13 15 0.0055 0.43 11.2 2.3 5 23 560 578 557 578 0.96

14 15 0.23 18 6.1 2.7 1 23 582 604 582 604 0.98

15 15 0.0053 0.42 11.3 0.2 1 23 610 633 610 633 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1	80	4.1	2.3	1	22	21	42	21	45	0.88
2	15	0.041	3.2	8.5	0.7	1	23	118	141	118	141	0.91
3	15	8.3e-06	0.00065	20.1	0.6	1	23	181	203	181	203	0.98
4	15	1.8	1.4e+02	3.3	2.0	1	23	226	249	226	249	0.89
5	15	1.3e-06	0.0001	22.7	0.2	1	23	289	311	289	311	0.97
6	15	0.016	1.3	9.7	2.2	1	23	317	340	317	340	0.94
7	15	0.00048	0.038	14.6	1.5	1	23	363	386	363	386	0.96
8	15	0.014	1.1	10.0	1.1	2	23	407	429	406	429	0.93
9	15	0.02	1.6	9.5	1.3	2	21	443	462	443	462	0.96
10	15	1.6e-06	0.00013	22.4	0.6	2	23	470	491	469	491	0.96
11	15	0.00067	0.052	14.1	1.3	1	23	497	520	497	520	0.96
12	15	0.0013	0.1	13.2	1.7	3	23	531	551	529	551	0.95
13	15	0.0055	0.43	11.2	2.3	5	23	560	578	557	578	0.96
14	15	0.23	18	6.1	2.7	1	23	582	604	582	604	0.98
15	15	0.0053	0.42	11.3	0.2	1	23	610	633	610	633	0.93

Sequence Information

Coding Sequence: ATGGAGCATTCGCAATTAACACACGCTCTCAATCCACCATCACCGGACCCAACGAGACCATTCCAGTGCAACATTTGCTACTGCTCTAGAAGAACAGAACGGGGTATAGAGCAGCATCGTAAAGTGCTGCAGCATCTGTGGATGAAAAAGTCCTCGATTGGCGCACAGATAGCAAGTGATGCCGCAAACAACTCTACAGCAAATAGTGTTGAGAATGAAGGATTCGAAGCTCATGGTAAAGAAATGCAAACCAATCCAAGCATCGACGACAGTTACACCGAGGAATTGATCGACAATGGATCAACCGACGTAGGGTGTTACGTGGTGTCATCGGCACCGGATGATCTTAAATTCAGCTGCTGCGGATGTACCCTCTCCTTCGGGACCGAGAATGAATTGATGGAACATTCCGATTCGATACATGCACCAAATGCGCCCCCGCcacacaaaaccaaaccagtgCAGTGCAACGTTTGCTATAGCTGGTATTCATCCGAGCGGTCTTGCCGGGACCATCAGGTCTACATGGGCAACCGTCAGTTTATGTGTCCGGTGTGTGGTATGCGCTTTGGCCGAACTTCTTCGCTACTGCGACATAAAAGCACACACGATAAAATACCGGACGAGGTGGAAGCGAGTCAGGTTGTTGAACCCGAGCTACTGGATGATCTACAGTTTAGCTGCTGCGGATGTATGCTCTGCTTCGAAACCGAGAATGAATTGATGGAACATTCCGTTTCGGTTCATGCACCAAATGCGCCACCGGAAGACGACAACAAGCCAGTGCAGTGCAACGTTTGCTATAGCTGGTATTCATCCGAACGGTCGTGTCGGGATCATCAGGTCTACATGGGCAACCGTCGGTTTGCGTGTACGATATGTGGCCAGCGCTTCGGTCGTGCTTCGGCCCTCGTACGCCATCGAAATACGCACGAAAAGGCACTCATATTTTCGTGCAAATATTGTGGAAAACTGTTTCCCAGCACGTACAAAAAGTTGAGCCACGAAAAACGGGAGCATGAGAACCCGCTCGTAAAGGGTACCGATACTGAATCGGCCggcgaagaacaaaaaaaaccacttATCTTTTCGTGCAAATATtgtgaaaaaatgtttgccaaCGCGTACAGCAGGATGAGCCACGAAAAACGGGAGCATGAAAATCCGCCCGTAAAGGATGCCGAAGCCGACTCGACCGGTGAAGActcaaaaaagcaaacatgctGTGGATGCAGTGAAACCTTCGATAGCGAGCACGAATTGATGGTCCATGCCGGTACGGTGCACGCCCCGAATGCACCCCCCGACGACGACGCGAAACCGGCCCGATGTAACATCTGTTATCGATGCTACAAATCCGATTCCGCTGTACGGGTGCATCAACGGTGCATGCGCATGCGCTCGCTGCAGTGTGCGACCTGTGGCAAGAGCTTCGCAACACGATCGCATCTGCTCGCACACGAAAACGTTCACACCCAAGCGTTGATCTACGCGTGCGCCCATTGTGACGAAAAGTTCGCCAACAAAACGGCCAAACAGAAGCATATCGCACGAAAACACGGCCCGCCGGTGGCCCCCACCAAGCATCTTTGTCTCACCTGTGGTAAagcattcaattcaattttctaTCTGCGAGACCATCTGAAGCTGCACGCTGACGAGATGCCATACTCATGTCACTGCGGTGCTAAGTTTAAGCTGGAAAAATACCTCAAAAGGCATATGCAAATACACAGCGGGAAGTACACGTGTCAGTTTTGCACCCTCGCCTATCGTTGCGCGTCCATGCTGCGGGACCACGAAAACCGGCACACGGGGAATAAGGAATTTCCCTGTGACCTCTGCAGCAAACGGTTCTACGGAAAAGCGGACGTGGCAAAGCATCGTGCCTATGTGCACTTTAAACGAGGGAAACTACGTAAAGCTTCTTCCTGA
Protein Sequence: MEHSQLTHALNPPSPDPTRPFQCNICYCSRRTERGIEQHRKVLQHLWMKKSSIGAQIASDAANNSTANSVENEGFEAHGKEMQTNPSIDDSYTEELIDNGSTDVGCYVVSSAPDDLKFSCCGCTLSFGTENELMEHSDSIHAPNAPPPHKTKPVQCNVCYSWYSSERSCRDHQVYMGNRQFMCPVCGMRFGRTSSLLRHKSTHDKIPDEVEASQVVEPELLDDLQFSCCGCMLCFETENELMEHSVSVHAPNAPPEDDNKPVQCNVCYSWYSSERSCRDHQVYMGNRRFACTICGQRFGRASALVRHRNTHEKALIFSCKYCGKLFPSTYKKLSHEKREHENPLVKGTDTESAGEEQKKPLIFSCKYCEKMFANAYSRMSHEKREHENPPVKDAEADSTGEDSKKQTCCGCSETFDSEHELMVHAGTVHAPNAPPDDDAKPARCNICYRCYKSDSAVRVHQRCMRMRSLQCATCGKSFATRSHLLAHENVHTQALIYACAHCDEKFANKTAKQKHIARKHGPPVAPTKHLCLTCGKAFNSIFYLRDHLKLHADEMPYSCHCGAKFKLEKYLKRHMQIHSGKYTCQFCTLAYRCASMLRDHENRHTGNKEFPCDLCSKRFYGKADVAKHRAYVHFKRGKLRKASS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109334;
90% Identity: iTF_00109334;
80% Identity: iTF_00109334;