Aste000718.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- -
- Assembly
- GCA_013141755.1
- Location
- CM023250.1:2269133-2273028[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.086 5 7.6 2.0 6 23 240 257 240 257 0.98 2 14 0.81 47 4.5 0.1 6 23 268 286 263 286 0.85 3 14 2.4e-05 0.0014 18.8 2.0 1 23 294 316 294 316 0.94 4 14 0.00027 0.016 15.5 1.0 2 23 325 346 324 347 0.93 5 14 0.32 19 5.8 0.4 2 21 400 419 399 422 0.87 6 14 5.6 3.2e+02 1.9 1.9 6 23 432 449 427 449 0.89 7 14 1.7e-05 0.00096 19.3 0.8 1 19 455 473 455 478 0.94 8 14 0.0011 0.061 13.6 2.9 1 23 486 508 486 508 0.96 9 14 0.066 3.8 8.0 5.2 3 23 518 539 516 539 0.96 10 14 0.00057 0.033 14.4 0.1 2 23 546 567 545 567 0.96 11 14 2.3 1.3e+02 3.1 7.1 1 23 577 600 577 600 0.96 12 14 0.00051 0.029 14.6 1.9 2 23 607 628 606 629 0.94 13 14 0.00012 0.0069 16.6 0.5 1 23 635 657 635 657 0.97 14 14 0.024 1.4 9.3 1.4 1 23 663 686 663 686 0.91
Sequence Information
- Coding Sequence
- ATGGACGATCATTCCGATCGGCAGCCGGCAAGGGATGAGGGTTGCTTGCTGTGTCAGTTATACGGCAACGATCGGCACTTCCTATCCGAACGGGTAGAAATCAGCAACGAGTCAATTGAAGACGTTATTGGCAAGCATTTCTGGTTGTCGGAAACCGCCAGCAACGAACGATACATCTGCGCCACCTGTTGGGACATAACATACTCCTTTCACCAGTTCTACATCCAAATAGAACGGCTGCATGCGGTGCAACTTACACCACAGGTTAAGCAGGAACAAACTGGCACCGAGCAAAAACCGGAATGGCTGCAGGAAGAGAACACACCGTTTGCCAATGAAATCTACGTGAAGGGAAACTGCACGGACAGTGACGATGAATCGTCAGCGCTCGTTGATTCCATCGCTGCCGTTGATcgggaatcggaatcggacaGCGATTCAAACATTCCTCTCTCGATGCTtaaggaaggaagaaacaaaattaagcGCAGCGAATCGCTCGAGCAAGACAATGTGCCAGCCGACAGACCATCTCCCTATTCCGGCGTGGGACTGTCCTTGTGCCGTATTAAGGGAAGTACGCTCGAGCTTATGTGTTACGACTGTTTTCGGCAGGCCGGAAAGGGTCCGCAAGACGTGTCCCAAGCCCGCTTCACGTTTGCCGCACTGCTGAAACACTTTCGGAAGGAGCACAACAAGAACGGTTATGCGGTTTGCTGCAGCCGGAAGTATACGCGCCGAAGATCGCTAAAGATGCACCTGCTGTCCCACGGTCGTACGGTTGTGTATCGATGCATTCCCTGTGGCATTAAGTTTCGCAAACAAGAATCGTTGGACGAGCACAATCTGCTGATCCACACGGCGGAGGAGGAAAAGCGGTTCAAATGTGACAAGTGTGATAAATCGTTCGCAACCGAACATCTGCTAAAGTCGCACGGATCGTGGCATGAAAATGTGGCCAATAAGAATATCAGCTGCAAGATTTGCAATATATATTTCACCAGTCAGCCGTCGCTGGAAAAGCATCGTGCCCTACATCACCCAGCACCGGAAACCACCGAAGCGATCTTCACATCcggtaacagcagcagcacggaaCCCACCGAAGACCGGCTAGTATCGTCCCAATATCGTACGCGCATTTCGGCCACCGAAATCACCGAACAGGAAGAACTCATCAAACGCCACTGTTTGCTAAACTGCAGCAAATGTGACTACTTTGCGGAAAGCTTCACCAACCTGAAGCAGCACGCGGTACAGGTGCACAGCCAACGAAGCTGTGATGTCGTGTGCTGCGACCGTACGTACAGTAAACGCCAATCGCTTTACGAACACTGCTTGGTACACGAAAATCCCGACTGCTTCCGGTGCGATGTGTGTGGGAAAAGCTACTCGAGCAGTCGCAGTCTGCAGAATCACAAATGGCGCATACATACGCCAGCGGCCGAGCGTCCATTTTGCTGTGACGTGTGCGGCGAAACGTTCGTGAAGGATTATCTGCTAAAGCAGCATTTGATACACCATTTGGCAAAGCACAAAAAGCTTAACCACTGTAACGAGTGTGAACGGTCGTTCACGACGGCGACGGTGCTCAAATGCCACCAGCAGACGTTTCACGGTGGTGGATTTAACTGGATCTGTGATATCTGTGCGAAAGGGTTCAACAGTCGGGCGCTGTTTGAAAATCACCGGTTAACCCACTCGGTCGAAGGAAAGTCGCAGCTGAAGCATCAGTGCGAGCAGTGCAAAAAATGGTtacgaaataaaaaatcctACCAGCAGCATCGCATACGGTGCCACACGAGCGATGGTCCGGTGACGTGTAAATTCTGCGGCAAAGAATCCGTCAATGCGAGTGCACTGAAGTCGCACATCCATCTGCATCACGCATCGCGACCCGAATATCCGTGCACGCTTTGCAACAAAAGCTTCAAGACGGCACTGCGATTAAAGGAACATGAGGCCACGCACACGGGTACGATACTATACCGGTGTCCGTGGTGTCCGCGTACCTTTGCCTGCGGTTCGAACATGTACAAGCATAAAAAGGCGGGCCATCCGCTGGAGTGGGCCGCTTCGGTGAAGAAACGGTTCGGTGAGCGATGA
- Protein Sequence
- MDDHSDRQPARDEGCLLCQLYGNDRHFLSERVEISNESIEDVIGKHFWLSETASNERYICATCWDITYSFHQFYIQIERLHAVQLTPQVKQEQTGTEQKPEWLQEENTPFANEIYVKGNCTDSDDESSALVDSIAAVDRESESDSDSNIPLSMLKEGRNKIKRSESLEQDNVPADRPSPYSGVGLSLCRIKGSTLELMCYDCFRQAGKGPQDVSQARFTFAALLKHFRKEHNKNGYAVCCSRKYTRRRSLKMHLLSHGRTVVYRCIPCGIKFRKQESLDEHNLLIHTAEEEKRFKCDKCDKSFATEHLLKSHGSWHENVANKNISCKICNIYFTSQPSLEKHRALHHPAPETTEAIFTSGNSSSTEPTEDRLVSSQYRTRISATEITEQEELIKRHCLLNCSKCDYFAESFTNLKQHAVQVHSQRSCDVVCCDRTYSKRQSLYEHCLVHENPDCFRCDVCGKSYSSSRSLQNHKWRIHTPAAERPFCCDVCGETFVKDYLLKQHLIHHLAKHKKLNHCNECERSFTTATVLKCHQQTFHGGGFNWICDICAKGFNSRALFENHRLTHSVEGKSQLKHQCEQCKKWLRNKKSYQQHRIRCHTSDGPVTCKFCGKESVNASALKSHIHLHHASRPEYPCTLCNKSFKTALRLKEHEATHTGTILYRCPWCPRTFACGSNMYKHKKAGHPLEWAASVKKRFGER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103922;
- 90% Identity
- -
- 80% Identity
- -