Aste004669.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- -
- Assembly
- GCA_013141755.1
- Location
- CM023249.1:65199594-65202006[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 1.3 75 3.9 0.5 2 23 233 254 232 254 0.89 2 11 1.6 90 3.6 0.2 12 23 282 293 279 293 0.86 3 11 0.0038 0.22 11.9 2.7 2 23 298 320 297 320 0.95 4 11 0.00059 0.034 14.4 0.7 1 23 329 351 329 351 0.99 5 11 5.1e-06 0.00029 20.9 0.8 1 23 359 381 359 381 0.98 6 11 6e-06 0.00035 20.7 1.9 1 23 387 409 387 409 0.97 7 11 0.0021 0.12 12.6 0.9 3 23 417 437 415 437 0.95 8 11 0.00053 0.031 14.5 4.6 1 23 482 505 482 505 0.97 9 11 0.0019 0.11 12.8 2.2 1 23 511 533 511 533 0.98 10 11 6.4e-07 3.7e-05 23.7 1.1 1 23 539 561 539 561 0.98 11 11 0.00033 0.019 15.2 1.8 1 23 567 591 567 591 0.95
Sequence Information
- Coding Sequence
- ATGGAATTGCAAGCGGAAGATGCATCCTGTCCAATGGAAACTTGTTGTACGTCATCGAGGAAAGCCGTACTACGCCGGTTCTGTCGGCTTTGCATGCGCGAACATCCGTTTCTGCTCCCTTTCGATGCGAAGCTAAACGAAAACACGATCGCCAATATGCTCGAGCGATTGTTGGGCGCATTTAGGCTGGAACAAACACCGAATCTACCGGACGGAGTCTGTCCACGCTGTGTGACGAAGCTGGACTATGCATACCACGTACAGAAAGAGTTGGTACGCAATGAGCATCGGTTGAGACACTACCAGCAGGAGGGCAATCTGCTGTCGAAGTTGTTTGAATATCAAACCCAAATCACTGTTTCGAAGGCAACCTACACGGACCGCATGATGGAAGAGCACGGTGACGGGTTGCTGGCAGAAAGAATCATGGTTGATGATAGCTATGACGCACCGAACATGCGTGAGGCCGAATCAACGGCTGCCACTTTGTTCGACACGCTGGAACCTCCTGCCCAGTGGGCTGTTGTGGCCTGTGACTGTCCACCGAAGCCGGCAGCACGTTTTCCAAGGCGGACTGTACGCCCCACTAGCTCCGTGCGTCCCCCAAAGCAAACGCTACTCAATCGACGTGTATTGCGCACGAAATTCGGTGCAGAAAATCCAACCGATGTGATCGTAACACCCATCGACCCTTGCAAATGTTACATATGCAATACCGTGCTGGAAACAGAGGAAGCACAAAGGGACCATCTGGTGGAGCATGTGAATATGCTGCCACACACGTGCCCCCAATGTTCGCGGGATGGTGAACAGGGCGAAGAAACGAATAATCCACCACTAACCTCGCTGGCAATGTTGCAGCGCCACTATCGAATGCATTCGTATCCACTGCAGTGTCCGCACTGTCCACAACGGTTCCGGAAGCATGCGTCGATTTACGCACACGTTCGCTACCGGCACGAACTGTTTGATAATCCGGAAGGATACACGTGTGACATATGTGGCGTCACGATGCGATACCGGCCCTCGTTCCGTTACCACATGCGTATTCACTATCACGAGCAGATGGGAACGTTCAAATGCCAGTACTGTGATCGTGTTTTTGGCACACGAGCCCGGCTAGAGCGGCACGAGCGGGTGCATACTGGCGAACGACCGTACGCATGCCATCTGTGCCCGAAAACGTTCATTCATTCGGGCCAGCTAGCGACACACATATCGCGCCATAACAATGAACGCGGTCACCTGTGTGCCCAGTGCGGGAAAGCGTTCCTGAGCAAGGCCATGTTGCGACAGCATCAGGAGTCACACGAAACGCACTCAACGCGGAAGGTTTCCactacgtacaaaatgcggccACGACCGTGTCAGTATGCCGGCTGTAATCACTTGGCTCGAACGTATCATGCCTACTACCTGCATCGGTTACGGCACGAAATGGCCCATCGGTGTGACGTCTGTGGTCGACGCTTTGCACGAGATTGTGAAATGAGACGGCATCGGCGTATCTACCACTCGTCCGAACACCCGTTCAAATGTGAGCAGTGCAGCAAAACGTTCCTTAGCTCGCAAAGCTACCGGGAGCATATGGATTCGCACGCCAACTTGCGCCGGTTTGAGTGTGATATTTGTGACAAAAAGTTTGTACGTCGACGCAATCTGGTCAATCATCGTATGTCCCATAGCAACGCTCGCCCGTACCGGTGCGAGGATTGCGATAGCGCGACGTTCAAGTACAAGAGCGATTTGAACCGACACCGGAAAGACAAGCATGGGCAGCAAGCGGAGCAGGAAGCTGATACGCTGACGCGAGACGGAGGCGTTGCCGTGGCGGAACAGATTGTGCTGCTGAACGAGGAAGATCCCGTGATGGATGGAATGCTCATAGAAAATGTACCGGAAGGTATATTGATAAATGAGGACATTGAGCTGGACGGGACGTACGGCGAAGTGATAGAAACGGTGGAAGAGTCCATCGTCGTGGAGCAACCGATTGTTAGCTTCGGTATCGATGAGGTGACCAAGGAGGAATATATTATAGAATATATTAACCATGGGTAA
- Protein Sequence
- MELQAEDASCPMETCCTSSRKAVLRRFCRLCMREHPFLLPFDAKLNENTIANMLERLLGAFRLEQTPNLPDGVCPRCVTKLDYAYHVQKELVRNEHRLRHYQQEGNLLSKLFEYQTQITVSKATYTDRMMEEHGDGLLAERIMVDDSYDAPNMREAESTAATLFDTLEPPAQWAVVACDCPPKPAARFPRRTVRPTSSVRPPKQTLLNRRVLRTKFGAENPTDVIVTPIDPCKCYICNTVLETEEAQRDHLVEHVNMLPHTCPQCSRDGEQGEETNNPPLTSLAMLQRHYRMHSYPLQCPHCPQRFRKHASIYAHVRYRHELFDNPEGYTCDICGVTMRYRPSFRYHMRIHYHEQMGTFKCQYCDRVFGTRARLERHERVHTGERPYACHLCPKTFIHSGQLATHISRHNNERGHLCAQCGKAFLSKAMLRQHQESHETHSTRKVSTTYKMRPRPCQYAGCNHLARTYHAYYLHRLRHEMAHRCDVCGRRFARDCEMRRHRRIYHSSEHPFKCEQCSKTFLSSQSYREHMDSHANLRRFECDICDKKFVRRRNLVNHRMSHSNARPYRCEDCDSATFKYKSDLNRHRKDKHGQQAEQEADTLTRDGGVAVAEQIVLLNEEDPVMDGMLIENVPEGILINEDIELDGTYGEVIETVEESIVVEQPIVSFGIDEVTKEEYIIEYINHG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103888;
- 90% Identity
- -
- 80% Identity
- -