Basic Information

Insect: Anopheles maculipalpis
Gene Symbol: -
Assembly: GCA_943734865.1
Location: CALSEK010000085.1:663662-665659[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3.7 2e+02 2.6 0.3 2 23 216 237 215 237 0.87

2 12 8.7 4.6e+02 1.4 0.4 1 9 243 251 243 251 0.86

3 12 2.5 1.3e+02 3.1 0.5 12 23 265 276 263 276 0.86

4 12 0.0028 0.15 12.4 3.7 2 23 281 303 280 303 0.96

5 12 0.0001 0.0054 16.9 1.2 1 23 312 334 312 334 0.99

6 12 5.5e-06 0.00029 20.9 0.8 1 23 342 364 342 364 0.98

7 12 2.1e-06 0.00011 22.2 1.7 1 23 370 392 370 392 0.97

8 12 0.00099 0.053 13.8 1.9 1 23 398 420 398 420 0.94

9 12 0.0002 0.011 16.0 3.4 1 23 463 486 463 486 0.96

10 12 0.0017 0.089 13.1 2.1 1 23 492 514 492 514 0.98

11 12 1.8e-06 9.4e-05 22.5 1.0 1 23 520 542 520 542 0.98

12 12 0.0049 0.26 11.6 3.0 1 23 548 572 548 572 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3.7	2e+02	2.6	0.3	2	23	216	237	215	237	0.87
2	12	8.7	4.6e+02	1.4	0.4	1	9	243	251	243	251	0.86
3	12	2.5	1.3e+02	3.1	0.5	12	23	265	276	263	276	0.86
4	12	0.0028	0.15	12.4	3.7	2	23	281	303	280	303	0.96
5	12	0.0001	0.0054	16.9	1.2	1	23	312	334	312	334	0.99
6	12	5.5e-06	0.00029	20.9	0.8	1	23	342	364	342	364	0.98
7	12	2.1e-06	0.00011	22.2	1.7	1	23	370	392	370	392	0.97
8	12	0.00099	0.053	13.8	1.9	1	23	398	420	398	420	0.94
9	12	0.0002	0.011	16.0	3.4	1	23	463	486	463	486	0.96
10	12	0.0017	0.089	13.1	2.1	1	23	492	514	492	514	0.98
11	12	1.8e-06	9.4e-05	22.5	1.0	1	23	520	542	520	542	0.98
12	12	0.0049	0.26	11.6	3.0	1	23	548	572	548	572	0.95

Sequence Information

Coding Sequence: ATGGAGTCCTACCCCACACCACCACAGAAAGTCGTAGTACGGCGATTCTGTCGGCTGTGTATACGAGAACATCCGTTTCTGCTACCGTTCGATGCCGCGTTAAAAGAAACCACAATCGCAAGTATGCTTGAGCGATTATTGGGCGCATTTAGGTTGGAACAAACGCCCAACTTGCCGGACGGTGTCTGTCCACGGTGTGTGACGAAGCTTGACTATGCGTACCACGTACAGGAAGAGTTTGTACGCAACGAGCATCGGTTGAGACACTTCCAGCAGGAGGGCAAACTGTTGTCGAAATTGTTTGAGTATCAAACTCAAATCGCTGTTACGAAGGAGAACTATACGGACCGTATGATCGAAGAGCACGGAAATGGCTTGCTAGCGGAAAGAATCGTGATTGATGGCAAGGATGACGCACCGAACATTCGTGAGGCCGAAACAACTGCTGCTACATTGTACAAAACTGTGGAACCTCCAGCCGACTGGACGGTGGTTGCTTGTGATTGTCCATCGAAACCAGCAACTAGTTCCAAAAGACGAACAGTACGTCCTCCAAAGCGAACGCTGCACAACCGACGTTTGCTTCGACAGACAATTGCTGCTGCAAATCCAACCGATGTGATCGTAACTCCCATTGACCCTTGCAAATGTTACATCTGCAATGCCGTACTGGAAACAGAGGAAGCACAGCGAGACCATCTGGTGGAGCATGTGAACATGCTACCCCACACGTGCCCCGAATGCTCCCGAACCGATGAACAGGGCGAAGAAGCGAATGTTTCGCCCATAACCTCGCTGGCAATGTTACAGCGCCATTATCGGATGCATTCGTACCCACTCAAGTGTCCTCACTGTCCACAGCGATATCGGAAGCATTCATCAATTTACGCACACATTCGCTACCGGCACGAACTGTTTGATAATCCCGAAGGATACACGTGTGACATATGTGGCGTTACGATGCGTTATCGATCTTCGTTCCGCTACCACATGCGAATTCACTATCACGAACAGATGGGAACGTTTAAATGTCAGTACTGTGATCGCGTTTTTGGCACACGAGCCCGGCTAGAGCGTCACGAACGAGTACATACAGGCGAACGGCCGTACGCATGCCATCTCTGTCCGAAAACATTTTCCCATTCCGGGCAACTAGCGACCCACATAGCGCGCCACAATAATGAACGTGGCCACCAGTGTATACAGTGTGGAAAAGCGTTCTTCAGCAAGGCCTTGTTGCGACAGCATCTAACATCACACGAAACGCACGAAACGCGAACCACTACGCACAAAATGCGACCACGGCCCTGTTTGTACGTTGGCTGTAAGCACGTGGCTCGAACGTATCAAGCGTACTATCTGCATCGCTTACGGCACGAAATGGCCCATCCGTGTGATGTGTGTGGTAAACGTTTTGCGCGCGATTGTGAGATGAGACGACATCGGCGTATCTACCACTCGGTGGACCATCCATTTAAATGTGAACAGTGCAGCAAATCGTTTCTTAGCTCGCAAAGCTACCGAGAGCACATGGATTCGCACGCCAATGTGCGCCGGTTTGAGTGTGATGTTTGTGACAAAAAGTTTGTACGGCGTCGCAATTTGGTCAGCCATCGGATGTCTCACAGCAACGTACGGCCGTACCGGTGTGAGGATTGTTATTTTGTGTCGTTTAAGTATAAGAGCGATTTAAATCGACACCGGAAAGATAAACATAAGCAGCAAGTGGAGCAGGAAGAAGATACGGTTACGCAAGAAGAGGATGGGGCCGGAGAGATTGTGCTGATGAGTGAGGAAAGTCCCGTAATGGAGGGAATGCTGATACAAACGGTAACGGACGATATATTGACCAGCGGGGATATTGAGCTAGACGGAACCTACGGTGAGGTAATCGAAACGGTGGAAGAATCTATCGTCGTTGAGCAGCCAATTGTGGGCTTCGGTATCGATGAGGTGACCAAGGAAGAATATATTATAGAATATATTAACCATGGGTGA
Protein Sequence: MESYPTPPQKVVVRRFCRLCIREHPFLLPFDAALKETTIASMLERLLGAFRLEQTPNLPDGVCPRCVTKLDYAYHVQEEFVRNEHRLRHFQQEGKLLSKLFEYQTQIAVTKENYTDRMIEEHGNGLLAERIVIDGKDDAPNIREAETTAATLYKTVEPPADWTVVACDCPSKPATSSKRRTVRPPKRTLHNRRLLRQTIAAANPTDVIVTPIDPCKCYICNAVLETEEAQRDHLVEHVNMLPHTCPECSRTDEQGEEANVSPITSLAMLQRHYRMHSYPLKCPHCPQRYRKHSSIYAHIRYRHELFDNPEGYTCDICGVTMRYRSSFRYHMRIHYHEQMGTFKCQYCDRVFGTRARLERHERVHTGERPYACHLCPKTFSHSGQLATHIARHNNERGHQCIQCGKAFFSKALLRQHLTSHETHETRTTTHKMRPRPCLYVGCKHVARTYQAYYLHRLRHEMAHPCDVCGKRFARDCEMRRHRRIYHSVDHPFKCEQCSKSFLSSQSYREHMDSHANVRRFECDVCDKKFVRRRNLVSHRMSHSNVRPYRCEDCYFVSFKYKSDLNRHRKDKHKQQVEQEEDTVTQEEDGAGEIVLMSEESPVMEGMLIQTVTDDILTSGDIELDGTYGEVIETVEESIVVEQPIVGFGIDEVTKEEYIIEYINHG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108619;
90% Identity: -
80% Identity: -