Aste009817.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles stephensi
Gene Symbol
L
Assembly
GCA_013141755.1
Location
CM023248.1:8082465-8101728[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.00046 0.027 14.7 3.6 1 23 165 187 165 187 0.97
2 18 0.69 40 4.7 5.7 1 23 193 215 193 215 0.98
3 18 5.7e-06 0.00033 20.7 3.7 1 23 221 243 221 243 0.99
4 18 1.7e-05 0.001 19.2 0.3 1 23 249 271 249 271 0.98
5 18 0.65 37 4.8 0.2 2 23 371 394 370 394 0.91
6 18 0.086 4.9 7.6 0.1 2 23 441 463 440 463 0.96
7 18 0.24 14 6.2 0.2 1 23 775 797 775 797 0.95
8 18 9.6 5.5e+02 1.1 0.7 1 23 845 867 845 867 0.89
9 18 0.00037 0.022 15.0 0.2 1 23 916 939 916 939 0.93
10 18 0.0026 0.15 12.4 0.9 1 23 946 969 946 969 0.97
11 18 0.004 0.23 11.8 1.6 1 23 1001 1023 1001 1024 0.96
12 18 0.5 29 5.2 0.2 1 23 1308 1332 1308 1332 0.91
13 18 0.00069 0.04 14.2 0.2 2 23 1341 1363 1340 1363 0.96
14 18 0.012 0.67 10.3 0.1 1 23 1370 1392 1370 1392 0.97
15 18 0.37 21 5.6 2.1 2 23 1400 1421 1400 1421 0.96
16 18 0.082 4.7 7.6 0.2 1 23 1604 1626 1604 1626 0.95
17 18 0.01 0.57 10.5 0.0 1 20 1636 1655 1636 1659 0.94
18 18 0.042 2.4 8.5 0.3 1 23 1667 1689 1667 1689 0.95

Sequence Information

Coding Sequence
ATGGCCCTGAAGATGCTTTACCGTGGCCCCAGCACCCGGTTGGAAACGTTGATTGAGAAAATACAGCAAAGCACGATGATTGCACCCGGCGCGTtgggtggtgctggtggcgggAAAGAGTTTTCCCTCGGTCAAGAACTCTACTCATCCCACACATCGTCCAGCTTTTCGCCCTCCATCTCGGACGGCATGACAACGCCCAATTCCATCACAAACGATACCAACGATGGGTCCCTGCATGGGCTGGGATCGGCCGAAGAAAAACCCTACCGGCAGGGAAGTAACCATCATCACATACATCCGCGCCATcaccatcttcatcatcgACGAACGGGCGGTGGCACGGGCGGACATTCATCGTCCGCCAAGGAAGGTGGCAAATCATCCTCCTTAAAGCATCACCATCAGCTGAATAATAATAGCAGCAGTCACAatcacaacaacaataacaacaacaaccatggGAGTAATAGCAAGGGCCTGAACAGCACCTACCACTGTCAGTTCTGTGAGAAGACGTTTCCGCGGCTCGGCTATCTTAAGAAGCATGAACAGAGCCACACGGAACACATGCCATTCAAATGCGAATACTGTGCCCGACTGTTCAAGCACAAGCGATCGCGCGATCGACACACGAAGCTGCATACGGGCGATCGACGCTACCGTTGTCTACATTGCGAGGCTGCATTCTCCCGAAGCGACCATCTAAAGATTCACATGAAAACGCACGACAACCAGAAACCGTTCCAGTGCACGATCTGTAACCGGGGATACAATACGGCGGCCGCCCTTACCAGCCATATGCAGAACCACAAGAAGCAGCTGGCACTGACCGGCAGTCCTAACCTGACGTACAGTCCGCGCTCCACCACAAGCTCTCTTTCGAGTGGTGGAGGaggaagtggtggtggtggtggtggtgggaagaGAGGATCCAAGTTCTCGCCCTACTCGAACGATCCTTTGCTGCTGATTGGTCGGAGTAGTTCCAAGCTGTCGTCCACGCTGGCGAAAGCTTCCTCCGGCAATGCTGGGTGCAATCGTACTCCAACACCGGGAAGTACGGGAGGAACGAGTGGACCTCCGACCGGAAGTCATGCCGATATGCTGTCCTGTCCGTACTGCACAAGAACCGATTTCACCACACTGGAACAGCTGGGAGTGCACGTACAATCCATGCACGGTCATGGTGCGCTAGGATTACTTGGTGCGGACACCCCAATGCCCTACTTCACACCCGGTGGTGGTAATCGACGGGCAGTGACACCGGATGCTAGCTCGCTGTCGCTTGGTAGCCTCGGCGGTCCTTACCCTCCGATCACCTGCGAGTTCTGCACGATGAAGTTCCCGACCGTACCGCTGATGTTTGCTCACCTGAAAACcgcccatctggaccgtttgACTGGGTCCGTCGGGGCATCAGGACCACCGCAGCGAAACTCACCGAACGGATCACGTCCACCGAGCGGGTTCCATCCACTGGACCAGCTACACTTCAACAAGAGTCTGCTCGGGAacgcttttccttccttctacGGTGCGATGGGGGGTTCTACGGCGCACGTTTCGGGAATGTCCGGTGGTAGCGTTAAGGTGGAGAATCGACCAGCAACCGGTGATATGAATGGGGGACGAGATGAGAATGGGAACGAATCGAGTGAGGTGGGCAGGAAGCGCAAGCGAAGGGGACTCGAAGATGGCGATAGGGAGGAAAGTGATCGTAAAAATGATGAAGAACACGATGTGGAAGACGAAGATGATGAAGGTGATGATGCTCCGCGGGATGAACACGATCGACCAGCTAATGCTGAAACAGTCGAAACGAAAGGCACACAGATAAagcaggaaaggaaggaagaaccCGAAAATGCCATTCCCGAAACTGCATCCCCATCCACCTCGACAAGGTCCTCGCCCTGTGATTCGTTGGGTTCGATTGGGCATCCAGCGAGCCACCCACCGTCCGGGCGGAACAGTCCCACGGAACAGCTCACTCCGACCGATCTTAGTCAGCCGAAGATGAAACGGTTAAAGCTAGAAACGTTGCTGGAGCACGAAGAACTGCCCGACCTGGAGCGGAAGATGATGGTTGGGGCTGGTCGGACACATAGTCGGGACCAccacaaacaacaacgtggTCCCTCGAATCGACGCGAAGCAGGTGATGCAAAGGAACCAAATCCGTCTaccacacagcagcagcacatttcCGTTCCTCAGCCACACTCCACAGGAACGAGCTGTAATGTGCACCAGCCTTCGCAGCAGTTGGGTGCTCCTGCTTCTACCGCATCCCAGCACGTCCATCAGCTGCCGGGAGCTTATCTCTGCAATCAGTGCAATGCAGCGCTGCCTGATTTTGAATCCTTCCGAACACATCTGAAGGCTCATCTGGAGCAGAGTGCTGCTAATgcggcggcggcagccgcCATGCGACTCTCCTCCGGCGATCACTCAAGCGGTCCTCCAGGCGGTACCACGAATAGCTCCTCAGCATCCGGTACATCCAGTGGATCGCTATCCCACACAACGTTCCTCTGTCAGCAGTGTGGAGCAACCTCGAGTTGCCAGGCCGAGTATGAGCAGCACACGATCGGTCACTTTCTCGTGATGGCGGTAGAATATCGCTGTCAGGCGGCGAACGCTAGTGGATCGTCGTCGGGAAACTCCTGCAGCACTAAACCTTCCTTCAGCAAGGTGGAAGACCTGCACAAACACCTCTACGAGGGTCACATGCAGCTGCTGTACAAGTGTACCGTTTGTGGGGAAACGTTCGAGTCTAAGGTGCAGGTGCAGGTCCACTTTGCCGTGAGCCATTCGGTTGAGGTGAAGCTGTACCGATGTTCGGCCTGTGTGGAGGTGTTCCGATCGGAGCGTGATTTTAGGCAACACATCCGGAACCGTCACTTGACAGCCGGGTCGATCCAATGTATGTTCTGTCGCATGGTTTGCTCGTCCGAGCTCGAGATGCACTTCCATCTCGCGTCGCACGCCAGGAAGTTTAAATGTCCTGCCTGTCCAGAATCGTTCCACGTGGAGTTCCTACTGGACCGCCACATTCAGACGCACCACAGTCAGAAGGAAACAGGCTCACCGAACCGTAGAGAAGTCACCGCATCGTCTACTGCACCGTCAACCACTTCGAATCCTTCTTTAACGGCCTCAACGGCATCGGGGACGTCGGTTTCCACAACGGTAACTTCGGCAGTGGCAGGTCTCGACTATCTTCACCTGCATGGTCAGATGGCAGCGAtggcagcagctgctgcgtGGCCCAGTCTTTACCAGACCGCCAACAAGTTCTACAGCAATCCGCTCCAGGTGGACACACTGAGTCAGCTGAAGCATCCACAGCACCTTCTGCACGGATTCTACGACACGATGCTCGGAAAGgcacaccaacagcagcagcagcagcagcagcagcaacagcaacaacgtgTCCCATTCCTTCCGGACACGCCGACTGGACCTGGAGGCAAGAAGAACCCTTTCTCAGGACACTCTCCCAACAGCAGCGCTACCAACGCACTACTCGGGCTTGGATATGGAACAGCACCAACAACTTCTGGGCCATCACAGCCTCAAAGAACTGCTGGACAGCAGCACACGCTTAATGGGACTTCATCCGGACTGTACTCACCTGAGGAACAGAACGCCGGAGCATCGAGTGTTTCCGCCACCGCCACTTCGAAGCTTTACTCTCCTATTGCCATGATCCAACGGTATGGTGATAGTAATGGCGGCGCGACACGTCCCACTGTAGAATCTCCACCATCAACCGGTCAGCTTCTTTTAGCATCAAGCTCATCTCTCGGACTGCCCGACCATCATAACGAACCGACGGCAAGAAAGACGAACCACCCGTCAAGCGCCAAGACAGCTTCGAGCGCTCCCAACACAGTCACTTCGAACAGCTGCTACAGCTGCGGTATCTGCGAGCGGTCCGATTTCACCACGGAAAGCGAGGTGCAAACCCATCGCAAGATTGTCCACAACTTAAAGACGGGCGTTAGCTTACGGTGCGCCTACTGCAACGGAGACTTCCGGTCGAGGAATGAGCTGGAGAACCACATGAAGGTCGCACACAATACGGGCGGTGGCAAGCACAAGTGTTTGATTTGTGACGAAATCTTCCCATCGCCGGCGGTGCTTGCGGAGCACAAGCTGTCCCACTGCAAGGTTGGTGCGTCGGGGCGCTGCTCGCACTGTAGCCTACCGCTGCCCGATGCGCACACCTTCAAGCAACATCTACAGGCTCACCAGGTTGTGACGGGTGGTGGAAGTTCGACGAATTCTTCCACAGGAACGTCGGGAGCAGGTTCCTGTTCTGCTAGCGGACAGAACGGTGGTTCTTCTTCCACAGGAACCAATGCTAGCACGTCCGGGAGCAGCAGTGCGGAGCAGGATCGATTCCCTCAACAGTGCATCTGCTGTCGGCAAACGCTCAACTCCGAGTTTGAGATCAGTCTGCACGCCAAaTTCCACACCAAATCGCCGGACACGAACGAGCGTACGTGTGCCCTCTGCCTGGAACCGCTTCCATCACAGCCCGAATCCAGCACCAAGATTTGTGACCCCTGTCTAAAGCGTCACAACTTCCCCACGAAGCTGCTCTCGATGAATTTCCTTAAGCCTGGTGCATCTTCATCCCTACCAGCAGCTACGACCATCGGTGGCCCCATCGTCGGAACGGCAGGTATTCCCGCCGTCGATGGAAGGACTCCGGTTTCCGCCTCCATCCAACAGGAACAGCAAGCATCCACTGGAAGGGATGGCTCATCGGCTTCATCCTCCACGTCGTCACCGTTCCAGTGTAATCTCTGCAAGAAACCACTTCCCTCGGGCCAGAAGCTACAGGAGCATCTGATCGATCACACGTTCGCTGGCTGTGAAGAACGAGGCTATGTGTGCTACCTTTGCTCTGCCGTGTTTACGTCCTCCGCTGGATTGCAGGCCCATCTTCCGGTGGCACACTCGAACGCAGCGGCAAAACCGTACGACTGTGAACGCTGTGGCGTGGCGTACTTCTTCCGTGCCGAGCTAGAGCATCACCTGATCGATCATGAGCTGGGAAGAACGATCAGACCGTTGGCGGCTGGCTCATTTGACCATCCACCAGCTGTAAGGACTGGAGACGGTGAGTGGCAGCACTCTAGGCAGCCCTCTCCGGTGTCGGATGATGACGGGTTACAGCGGGAGTCACAGCATCGCCAAATCAAGCAGGAACTTTGTGAGCAAGAGCAACGGGAACAGGAAGGATCCTCACCGCACCGACCAAAGGATGAGGATTTGGATCGGGAAAACGAGCTGGAACCAGCTGGAAATGAAGAACCAGAAAACAAGGGACAGCTAGAAGATGAAGATGACCGGGAAGAGGATGATGATTCTGCTAGTGAGAATCCCCATCACCAAGAGCAGGAAAACGATCTAGTAGACACTGAAGAATGTAACGAAGCAGCAACCAATGATGATGCGATGGAGGAATGTGAACAGCACGAGGACcaggaagatgaagaagagtACATCGAAGTAGAACACACGACGCTGGATGATGGCGCGAAAGGAACCACCCATGAACGTCTACATCGTCGGTCCTCGAACATGTTATTGAATGGTGGAAAGGATTGTTCTACACTCACAGTCGCTACTACAACTAGCACGACCCTTCCAGTTGTTACTGCGGCTGAGTAG
Protein Sequence
MALKMLYRGPSTRLETLIEKIQQSTMIAPGALGGAGGGKEFSLGQELYSSHTSSSFSPSISDGMTTPNSITNDTNDGSLHGLGSAEEKPYRQGSNHHHIHPRHHHLHHRRTGGGTGGHSSSAKEGGKSSSLKHHHQLNNNSSSHNHNNNNNNNHGSNSKGLNSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGGSGGGGGGGKRGSKFSPYSNDPLLLIGRSSSKLSSTLAKASSGNAGCNRTPTPGSTGGTSGPPTGSHADMLSCPYCTRTDFTTLEQLGVHVQSMHGHGALGLLGADTPMPYFTPGGGNRRAVTPDASSLSLGSLGGPYPPITCEFCTMKFPTVPLMFAHLKTAHLDRLTGSVGASGPPQRNSPNGSRPPSGFHPLDQLHFNKSLLGNAFPSFYGAMGGSTAHVSGMSGGSVKVENRPATGDMNGGRDENGNESSEVGRKRKRRGLEDGDREESDRKNDEEHDVEDEDDEGDDAPRDEHDRPANAETVETKGTQIKQERKEEPENAIPETASPSTSTRSSPCDSLGSIGHPASHPPSGRNSPTEQLTPTDLSQPKMKRLKLETLLEHEELPDLERKMMVGAGRTHSRDHHKQQRGPSNRREAGDAKEPNPSTTQQQHISVPQPHSTGTSCNVHQPSQQLGAPASTASQHVHQLPGAYLCNQCNAALPDFESFRTHLKAHLEQSAANAAAAAAMRLSSGDHSSGPPGGTTNSSSASGTSSGSLSHTTFLCQQCGATSSCQAEYEQHTIGHFLVMAVEYRCQAANASGSSSGNSCSTKPSFSKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACVEVFRSERDFRQHIRNRHLTAGSIQCMFCRMVCSSELEMHFHLASHARKFKCPACPESFHVEFLLDRHIQTHHSQKETGSPNRREVTASSTAPSTTSNPSLTASTASGTSVSTTVTSAVAGLDYLHLHGQMAAMAAAAAWPSLYQTANKFYSNPLQVDTLSQLKHPQHLLHGFYDTMLGKAHQQQQQQQQQQQQQRVPFLPDTPTGPGGKKNPFSGHSPNSSATNALLGLGYGTAPTTSGPSQPQRTAGQQHTLNGTSSGLYSPEEQNAGASSVSATATSKLYSPIAMIQRYGDSNGGATRPTVESPPSTGQLLLASSSSLGLPDHHNEPTARKTNHPSSAKTASSAPNTVTSNSCYSCGICERSDFTTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCSLPLPDAHTFKQHLQAHQVVTGGGSSTNSSTGTSGAGSCSASGQNGGSSSTGTNASTSGSSSAEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPESSTKICDPCLKRHNFPTKLLSMNFLKPGASSSLPAATTIGGPIVGTAGIPAVDGRTPVSASIQQEQQASTGRDGSSASSSTSSPFQCNLCKKPLPSGQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPVAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGRTIRPLAAGSFDHPPAVRTGDGEWQHSRQPSPVSDDDGLQRESQHRQIKQELCEQEQREQEGSSPHRPKDEDLDRENELEPAGNEEPENKGQLEDEDDREEDDDSASENPHHQEQENDLVDTEECNEAATNDDAMEECEQHEDQEDEEEYIEVEHTTLDDGAKGTTHERLHRRSSNMLLNGGKDCSTLTVATTTSTTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00103864;
90% Identity
-
80% Identity
-