Basic Information

Insect: Anopheles maculipalpis
Gene Symbol: L
Assembly: GCA_943734865.1
Location: CALSEK010000269.1:47384-66977[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00052 0.028 14.7 3.6 1 23 175 197 175 197 0.97

2 18 0.78 42 4.7 5.7 1 23 203 225 203 225 0.98

3 18 6.5e-06 0.00035 20.7 3.7 1 23 231 253 231 253 0.99

4 18 2e-05 0.0011 19.2 0.3 1 23 259 281 259 281 0.98

5 18 0.83 44 4.6 0.2 2 23 375 398 374 398 0.90

6 18 0.2 10 6.6 0.1 3 23 442 463 440 463 0.96

7 18 0.27 15 6.2 0.2 1 23 773 795 773 795 0.95

8 18 4 2.1e+02 2.5 0.9 1 23 841 863 841 863 0.90

9 18 0.00043 0.023 15.0 0.2 1 23 912 935 912 935 0.93

10 18 0.0048 0.26 11.7 0.7 1 23 942 965 942 965 0.97

11 18 0.0032 0.17 12.2 1.5 1 23 997 1019 997 1020 0.96

12 18 0.56 30 5.2 0.2 1 23 1320 1344 1320 1344 0.91

13 18 0.00078 0.042 14.2 0.2 2 23 1353 1375 1352 1375 0.96

14 18 0.013 0.7 10.3 0.1 1 23 1382 1404 1382 1404 0.97

15 18 0.41 22 5.6 2.1 2 23 1412 1433 1412 1433 0.96

16 18 0.066 3.5 8.1 0.2 1 23 1624 1646 1624 1646 0.96

17 18 0.17 9.2 6.8 0.0 1 20 1656 1675 1656 1679 0.94

18 18 0.048 2.6 8.5 0.3 1 23 1687 1709 1687 1709 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00052	0.028	14.7	3.6	1	23	175	197	175	197	0.97
2	18	0.78	42	4.7	5.7	1	23	203	225	203	225	0.98
3	18	6.5e-06	0.00035	20.7	3.7	1	23	231	253	231	253	0.99
4	18	2e-05	0.0011	19.2	0.3	1	23	259	281	259	281	0.98
5	18	0.83	44	4.6	0.2	2	23	375	398	374	398	0.90
6	18	0.2	10	6.6	0.1	3	23	442	463	440	463	0.96
7	18	0.27	15	6.2	0.2	1	23	773	795	773	795	0.95
8	18	4	2.1e+02	2.5	0.9	1	23	841	863	841	863	0.90
9	18	0.00043	0.023	15.0	0.2	1	23	912	935	912	935	0.93
10	18	0.0048	0.26	11.7	0.7	1	23	942	965	942	965	0.97
11	18	0.0032	0.17	12.2	1.5	1	23	997	1019	997	1020	0.96
12	18	0.56	30	5.2	0.2	1	23	1320	1344	1320	1344	0.91
13	18	0.00078	0.042	14.2	0.2	2	23	1353	1375	1352	1375	0.96
14	18	0.013	0.7	10.3	0.1	1	23	1382	1404	1382	1404	0.97
15	18	0.41	22	5.6	2.1	2	23	1412	1433	1412	1433	0.96
16	18	0.066	3.5	8.1	0.2	1	23	1624	1646	1624	1646	0.96
17	18	0.17	9.2	6.8	0.0	1	20	1656	1675	1656	1679	0.94
18	18	0.048	2.6	8.5	0.3	1	23	1687	1709	1687	1709	0.95

Sequence Information

Coding Sequence: ATGGCCCTGAAGATGCTTTACCGTGGCCCTAGTACGCGATTGGAAACATTGATTGAGAAAATACAGCAAAGTACGACGAACGCGTACACGGCCGGTGGCACCATGATTGCACCCGGTGCATCATTGGGTGGTGGTGTGAAGGAGTTTTCCCTCGGTCAAGAACTCTACTCATCGCACACATCATCCAGCTTTTCGCCCTCAATTTCGGACGGGATGACAACGCCTAATTCCATCACAAACGACACTAATGATGGTTCCATGCTTGCGCTGGGATCCAATGATGAAAAACCCTTCCGGCAGGGAAGTAATCATCACATCCATCCTCGCCATCATCACCTACATCATCGCCGAACGGGAGCTGGTGGTGGAGGACATTCATCGTCCACGAAAGAGGGTGGCAAatcgtcgctaaaacatcatcaccatcagctgaacaataatagcagcagtcataatcacaacaacaataataacaacaacaacaaccatcaagggagcaacagcaagggcctgaacagtacctaccactgtcagtTCTGTGAGAAGACGTTCCCGCGGCTCGGCTATCTCAAGAAGCACGAACAGAGTCACACGGAACACATGCCATTCAAATGCGAGTACTGTGCACGGCTGTTCAAGCATAAACGATCACGCGATCGTCACACGAAGCTACATACGGGCGATCGGCGCTACCGTTGTCTGCATTGTGAAGCCGCATTCTCCCGAAGTGATCATCTTAAAATTCACATGAAAACACACGACAACCAGAAACCGTTCCAGTGTACGATCTGTAATCGAGGGTATAATACGGCGGCTGCCCTTACCAGCCATATGCAGAACCACAAGAAGCAGCTAGCACTGACCGGTAGTCCGAACCTTACGTACAGTCCACGCTCTACGACAAGCTCTCTGTCGAGTGGTGGTGGTGGTGGAAAGAGAGGATCCAAATTCTCACCTTACTCCAACGATCCTTTGCTGCTGATGGGTCGCGGTAATTCCAAGCTGTCATCCACACTGGGGAAAGCTTCTTCTGGGAATGCTGGTAGTACTCGCACACCAACTCCAGGCAGTACTACGGGTGGAACCGTTGCACCTTCGGCGGGAAGTCATGCAGATCTATTATCCTGTCCATACTGCACACGAACCGATTTCTCCACACTCGAACAGCTTGGAATTCACGTACAGTCCATGCATGGTCATGGAGCGCTAGGACTACTGGCGGCAGACACACCGATGCCCTACTTCACACCCGGTGCTAGCCGACGTGCAGTGACACCGGACGCTAATTCACTTTCTCTCGGTGGTCCTTATCCTCCCATCGCATGCGAGTTTTGTACAATGAAATTCCCAACAGTACCGCTGATGTTTGCTCACCTAAAAACCGCCCATCTGGACCGTTTGGCAGGGACGCCAGGTCCTCAGCGAAGCTCACCGAATGGATCACGTCCAACGAGTGGATTTTATCCGCTAGAACAATTACACTTCAACAAGAGCCTGCTCGGGAACGCTATTCCCGCATTCTACGGTGCGATGGGAGCTTCGTCCAACGTTTCCGGAATGTCCGGTGGTAATATTAAGCAGGAAATTCGAGCAGCAACGGGTAGCATGAATGGTGGGCGAGACGAGAATGGGAATGAATCGGAAAACGTGGGAAGGAAGCGTAAACGAAGAGTCGTAAACGAAGAGCCCGAAAAGGAAACAAATGATCGTAAAAATGATGTCGAAAATGATGAGGAAGACGAAGATGAAAGTGAGGATCATCGGCCGGATGTAAATGACCAATCAGATCCACCTGATAACTTCAAAGATACAATCGATACTGAAGGCACACAGATTAAGCAAGAAAGGAAGGAAGAATCTGAAAATCCCCTTCCCGAAACTGCATCCCAATCCACCTCAACACGGTCCTCTCCTTGCGATTCTTTGGGCTCGATTGGACATCCTGCGAGTCACCCACCGTCCGGACGAAATAGTCCCGCGGAACAGCTCACACCGACCGATCTCAGTCAGCCGAAGATGAAACGATTAAAGCTAGAAACGTTGCTCGAGCATGAAGAAGTGTCCGATTTGGATAGAAAGATGATGGTTGGGGCCGGTCGCTCTCATAGTCGAGAGCATCACAGCAAACAGCGCGGTCCTTCAAACCGAAGAGAAGGAAATGATCCGAAGGAGCCGAATCTATCCACCGCACAACAAATTTCCGTTCCTCAGCTACACTCATCTGGAGGTAGTTGTAGTGGCCAACCCTCACAACCGTTAGGAGCTCCCGCTTCTACACCCTCATCCCACCAGCACGTTCATCAGCTTCCGGGAGCTTATCTCTGCAATCAGTGCAATGCTGCACTACCCGATTTCGAGTCTTTCCGTACCCATTTGAAGGCACATCTTGAGCAGAGCGCTGCAAATGCTGCAGCGGCAGCTGCCATGAGACTTTCCGGTGATCACCAAACCGGTCCGGGAGGTACCAACAATAGCTCCTCCACGTCAGGAGTATCTGCAGGATCACTTTCCCACACAACGTTCCTCTGTCAACAGTGTGGAACAACGCTCAGCTGTCAGGCTGAGTACGAGCAGCACACGATCGGCCATTTTCTCGTGATGGCAGTAGAATATCGTTGTCAGGCGGCAACGTCATCCGGTGCTTCATCCGGAACATCCTGCTCCGCGAAACCATCCTTCAGCAAGGTGGAAGATCTCCACAAACATCTGTACGAAGGTCACATGCAGCTCCTGTACAAGTGTACCGTCTGTGGGGAAACGTTCGAATCGAAGGTTCAGGTGCAGGTCCATTTTGCCGTAAACCATTCGGTTGAAGTGAAGCTATATCGGTGCTCGGCTTGTGCAGAGGCTTTCCGATCGGAGCGTGATTTCCGGCAACATATAAGGAACCGACACTTGACAGCAGGCGCGATCCAATGTATGTTCTGTCGAATGGTTTGCTCGTCCGAGCTCGAGATGCATTTCCATCTCGCGTCACACGCTAGGAAGTATAAGTGTCCTGCTTGTCCCGAATCATTCCACGTTGAGTTCCTGCTTGACAGACATATTCAGACGCATCACAACCAGAAGGAAACAGGCTCTCCAAATCGTAGAGAGGTTACAGCGTCGTCTACTACAGCATCTACCACATTAAACCCTTCCTTAACGCCTTCGACAGCTTCGGGGACGTCTATATCTACAACCGCAACTTCAGCAGTAGCAGGACTCGATTACCTTCATCTGCATGGTCAAATGGCGGCGATGgcagcagctgctgcatggcccagtctttatcaaactgccaacaagttctacaacaatccgctccaggtggacacactgaatcagttgaagcatccacagcacttgctgcacggattctatgacacaatgctaggaaaggcacaccaacagcagcagcagcagcagcaacagcagcagcagcagcagcagcaacaacaacGtgttccattccttccggataattcatctggacctagcagcAAGAAGAATCCTTTCTCAGGTCACTCTCCGAATAATAGTGCAACTAACGCACTGTTAGGACTTGGTTACGGAACACCATCGACATCCACCGGTCCATCACAACCACAAAGAACTGCTGTTTCGCATACGCTTAATGGAACTTCCTCCGGACTTTACTCCCCTGAGGAAGCTAACAATGGAGGAGCGACTGGCGCCGGAGCTACTTCGAAGCTATACTCTCCTATTGCCATGATCCAACGGTACGGCGACAATAATGGCGGAACAACACGCCCGAGCGTAGAATCGCCCCCATCAACCGGCGGTCAGCTTCTGTTGACCTCAAACTCATCTCTCGGACTTGTGGACCATCATAACGATCAGGCGGCAACAAGAAAGTTGAACCAGTCATCAAGCGCCAAAACAGCACCGACAGCTCCCAACAGTACACTCACCCATCAGCAACAAATGTCTGCTTCTGCGGCAACCGCCAGCTGCTACAGCTGCGGTATCTGCGAACGGTCCGATTTCACTACGGAAAGCGAAGTGCAAACGCATCGCAAAATTGTCCACAACTTAAAGACGGGTGTTAGTTTGCGGTGCGCGTACTGCAATGGAGACTTTCGGTCGAGGAATGAGCTGGAGAATCACATGAAGGTCGCCCACAATACGGGCGGTGGCAAGCACAAGTGTTTGATTTGTGATGAAATCTTCCCATCGCCGGCAGTGCTTGCCGAGCATAAGCTGTCTCACTGTAAGGTTGGTGCGTCGGGGCGCTGTTCGCACTGCAGCTTGCCATTACCCGATGCGCACACGTTTAAGCAACATTTGCAGGCTCATCAGCTTGTGACGGGTGGCGGAAGCTCCACGAATTCTTCAGCATCAGCAGCAGCAGTTTCCTGCTCGTCCAGTGGCCAGAATAATGGTGCAGGAGGCAACTCTTCGGGCTCCTCGACAGGAACCAGCGCAAATGCGTCTGGGAGCGCTAGTGCTGAGCAGGACCGCTTCCCCCAACAGTGTATCTGCTGTCGGCAAACGCTCAACTCCGAGTTTGAGATTAGTCTGCATGCCAAATTCCACACCAAATCCCCGGACACTAATGAGCGTACGTGTGCCCTCTGTCTGGAACCGCTACCATCTCAACCCGAATCCAACACCAAAATTTGTGATCCTTGTCTCAAACGGCACAACTTTCCCTCCAAGCTTCTGTCGATGAATTTCCTTAAGCCTAGTGCACCTTCATCGCTAGTAGCGGCTTCCACCAACAGTGGTCCTATCACTGGAACGGCAAACGTTCCTGTCGATGGAAGGACTTCAGCTACTACCAGCATCCAACACGAGCAGCCAGGACAAACCGCAGGAAGGGATGGAATCTCATCTTCTTCCTCGTCCACATCCACGTCCTCACTGTTCCAGTGTAATCTCTGCAAGAAACCACTTCCAACTGGCCAGAAACTACAGGAACACCTGATCGATCATACGTTCGCGGGCTGTGAAGAGCGAGGCTACGTGTGCTACCTTTGCTCTGCTGTGTTTACGGCCTCTGCCGGGTTGCAGGCTCATCTTCCGGTAGCACACTCGAACGCCGCAGCTAAACCTTACGATTGTGAACGTTGCGGAGTGGCGTACTTCTTCCGAGCTGAGCTAGAGCATCATTTGATCGATCATGAACTGGGAAGAACGATCCGACCCATGGCTGCTAGTTCGTTTGAACACCCGACCGTACGGTGTGGAGGTGATGAGTGGCACTCTAGACAGCATTCCCCTGTGTCGGAAGATGACGGATCGCAACGAGAGTCGCAAAAGCACCACATCAAGCAGGAACTTTGTGAGACAGAGCATCAGGAACAGGCAGGTTCCTCGCCATACCATCGGGAAAAGGAGGAGCATTCGGATGAGGAAAATGAACCAGACCAACCAGTCGGAAAAGAAGAAATAGAAAACAAAGAACAAATAGAGGACGAAGATGGCGAGGAACATGATGATGGTGGGAACGATTCTACTACAAGTGAAACTACCCATCATCAAGACAAGGAAAATGATCGCCTCGGCGATCTAGGAAACACAGAAGAAGGTAACGAAGCAACCAATGAAGATGAGATGGAAGAACGTGAGCATCCAGGGGATCAGGAAGATGAAGAAGAGTATATTGAAGTAGAGCACACCACGATGGAGGAAGGTGCGAAACATCGTCGTACCTCGAACATGCTAATCAATGGTGGAAAAGATTGTTCTACACTAACCACCATCGCTACGACAACTACCGCGACCCTTCCGATTGTTACTGCGGCTGAGTAG
Protein Sequence: MALKMLYRGPSTRLETLIEKIQQSTTNAYTAGGTMIAPGASLGGGVKEFSLGQELYSSHTSSSFSPSISDGMTTPNSITNDTNDGSMLALGSNDEKPFRQGSNHHIHPRHHHLHHRRTGAGGGGHSSSTKEGGKSSLKHHHHQLNNNSSSHNHNNNNNNNNNHQGSNSKGLNSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGGGKRGSKFSPYSNDPLLLMGRGNSKLSSTLGKASSGNAGSTRTPTPGSTTGGTVAPSAGSHADLLSCPYCTRTDFSTLEQLGIHVQSMHGHGALGLLAADTPMPYFTPGASRRAVTPDANSLSLGGPYPPIACEFCTMKFPTVPLMFAHLKTAHLDRLAGTPGPQRSSPNGSRPTSGFYPLEQLHFNKSLLGNAIPAFYGAMGASSNVSGMSGGNIKQEIRAATGSMNGGRDENGNESENVGRKRKRRVVNEEPEKETNDRKNDVENDEEDEDESEDHRPDVNDQSDPPDNFKDTIDTEGTQIKQERKEESENPLPETASQSTSTRSSPCDSLGSIGHPASHPPSGRNSPAEQLTPTDLSQPKMKRLKLETLLEHEEVSDLDRKMMVGAGRSHSREHHSKQRGPSNRREGNDPKEPNLSTAQQISVPQLHSSGGSCSGQPSQPLGAPASTPSSHQHVHQLPGAYLCNQCNAALPDFESFRTHLKAHLEQSAANAAAAAAMRLSGDHQTGPGGTNNSSSTSGVSAGSLSHTTFLCQQCGTTLSCQAEYEQHTIGHFLVMAVEYRCQAATSSGASSGTSCSAKPSFSKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVNHSVEVKLYRCSACAEAFRSERDFRQHIRNRHLTAGAIQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHNQKETGSPNRREVTASSTTASTTLNPSLTPSTASGTSISTTATSAVAGLDYLHLHGQMAAMAAAAAWPSLYQTANKFYNNPLQVDTLNQLKHPQHLLHGFYDTMLGKAHQQQQQQQQQQQQQQQQQQRVPFLPDNSSGPSSKKNPFSGHSPNNSATNALLGLGYGTPSTSTGPSQPQRTAVSHTLNGTSSGLYSPEEANNGGATGAGATSKLYSPIAMIQRYGDNNGGTTRPSVESPPSTGGQLLLTSNSSLGLVDHHNDQAATRKLNQSSSAKTAPTAPNSTLTHQQQMSASAATASCYSCGICERSDFTTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLSHCKVGASGRCSHCSLPLPDAHTFKQHLQAHQLVTGGGSSTNSSASAAAVSCSSSGQNNGAGGNSSGSSTGTSANASGSASAEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSPDTNERTCALCLEPLPSQPESNTKICDPCLKRHNFPSKLLSMNFLKPSAPSSLVAASTNSGPITGTANVPVDGRTSATTSIQHEQPGQTAGRDGISSSSSSTSTSSLFQCNLCKKPLPTGQKLQEHLIDHTFAGCEERGYVCYLCSAVFTASAGLQAHLPVAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGRTIRPMAASSFEHPTVRCGGDEWHSRQHSPVSEDDGSQRESQKHHIKQELCETEHQEQAGSSPYHREKEEHSDEENEPDQPVGKEEIENKEQIEDEDGEEHDDGGNDSTTSETTHHQDKENDRLGDLGNTEEGNEATNEDEMEEREHPGDQEDEEEYIEVEHTTMEEGAKHRRTSNMLINGGKDCSTLTTIATTTTATLPIVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108605;
90% Identity: -
80% Identity: -