Aste003518.1
Basic Information
- Insect
- Anopheles stephensi
- Gene Symbol
- -
- Assembly
- GCA_013141755.1
- Location
- CM023249.1:76494904-76497932[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 7.5 4.3e+02 1.5 1.5 2 23 228 250 228 250 0.93 2 17 0.0031 0.18 12.1 0.1 2 21 260 279 259 280 0.94 3 17 0.0055 0.32 11.3 0.4 1 21 287 307 287 308 0.95 4 17 0.19 11 6.5 3.6 2 23 422 444 421 444 0.96 5 17 0.05 2.9 8.3 0.8 3 21 458 476 457 477 0.93 6 17 0.019 1.1 9.7 2.5 1 21 484 504 484 509 0.92 7 17 0.004 0.23 11.8 0.5 3 23 588 609 587 609 0.96 8 17 3.1 1.8e+02 2.7 1.2 1 20 622 641 622 643 0.92 9 17 0.00051 0.029 14.6 1.6 1 22 652 673 652 677 0.94 10 17 0.015 0.84 10.0 0.9 2 23 742 766 741 766 0.84 11 17 4.2 2.4e+02 2.3 0.5 3 20 784 801 783 803 0.92 12 17 0.00095 0.055 13.7 0.3 1 23 810 833 810 833 0.93 13 17 1.4e-06 8.2e-05 22.6 0.4 1 23 840 862 840 862 0.98 14 17 6.8e-05 0.0039 17.4 1.7 1 23 868 891 868 891 0.94 15 17 7.6e-05 0.0044 17.2 2.2 1 23 897 919 897 919 0.98 16 17 0.39 22 5.5 3.0 1 23 925 948 925 948 0.91 17 17 2.4e-05 0.0014 18.8 0.8 1 23 954 976 954 976 0.99
Sequence Information
- Coding Sequence
- ATGTCGAAACGTAGAAAGATCTCTAACGTAGAGGAGCACGATGTTGGATCCTCGTCCGAACACCATGGGAATGGTGAAAGGCTTCTCTCAAAATGCTGCATCTGCTCCAAACATCCGAAGGGAGGTTTGCTCGAGCTTTGTACAAGTGTGGAAAGCGGCCTAACAATTGCCACCATCGTCGAGCAGGTGGCCGGCATTAAGGTAAAACACGTCCAGAAAAGCATTTGCAATGCTTGCTGGACAAAGATACAGGCGGCCTACACCATACAGAAGGAAATCCGAGGCTCAGAATGTATAGAAGAGCAGGACGTGCAGGATGATTATGAGATCGACGATCCGCTCGATGCGAAGGCTGAATTGCACACAAGAGAAGTCGACGACTACGATGAGGAACATCTGGAAAACGAGGATGTATTCGTCAAGCAGGAAGCTGTACTGCCCGATGAAGAGTACCTGATCGAATATCTCGAAGAACATGTGTATGATAACGATGAAGAACAGACACAGCCAGCGCATGGCGACGACACGGACATTGCGATCGAAATATCTGCCACTGACAAGTACGAGGAACCGAGCGAGGAGTATGGTAAAGTGACGCGCGTGTTTAAAATGCCCGACACAGCAACGATCGTGAGCATTGCGATGCATGAGCAGTACCGCGTGGTTGAGGTAACGGGGGAACGGTGCTGCGGCTGCAGCTTCGTGGCTCAAACACGCAAGGAACTGCTGCAACATTCGGAAACGGTCCACTGCGTCGAAATTACCGACCACGGGGACTATTGTCCGATTTGTTTCTACAAGTTTGCGTCCGATCAGCAGCTCGAGAGACACATCCAAGAGTTTAAGCTGAACAAAATGTTTGTCTGCTTGCGTTGCAACCGTTTCTTCAACGTGCGTGGCCAGCTGTTCGAGCATATGGAGCGCTGCAGAGAAGCCGGTGAGATGTCAGCAATGGAAAACGATCCGGAAAGAAAAGCGGTAACGATTGAACGTATCCAGGAGGACGATACTGAATGTGAAGAGTATTATGAACAGCAGGAAGCCGACGCAGAAGAGGAACACGCGCTACCACAACGGGACGgtcacacacaaaacgcatCGGATCCGCGTGTGATGCACCGTTACAAAGCTCTGTTCGAGGAGATACTGTCGAACGAAGAGCTATCAAGCCCCCTAACCGAATCGGACCTCAATGTTCAGGAAACGCAAATAACGGCCCAGCATGTGTTCGAAACGTTCAAGTACGTTCGGTTACGAGGATTGCGTTGTTGTGGCTGCTCCTACACATGCTACTCGAGCGATCTATTGCTAGAGCACGGAAAAACAAGTCACCCTATGgaagccgccgccgccgcctccAGCTATCCATCGTGCCAGCTGTGCTGGACCCGTTTCCCCAACGAAACGGAGCTTGTGAAGCATTTGTGCTTTTTCTCCACCAAACAGCTATTCTTCTGCACGGTTTGCGACGAGTCGTTCCTGAACCACGAAAGCTTGCGGCACCATCAGCTGCGCAACGAGCTGCACCGGGAGCAGGTGCACCAGAGATTCCAGGAGGCCGGAATCGAAATGCTCGAACCAGCGGAACCGTTCGTCGAGCTTGATCAACCATCGATCGTTGACGAGCTGGGGAAACTGTTGGCCGAAAAGGTCACGTACCGGCCGAAGGCGATACGCTGCATTCCGATGCCGTCTGAACAGTTCATTAAGAGCAAGGTGGAGTACAACAACTACAGCACACTTACCGTCGAGGGTGAATATTGCTGTGGATGTGCGCGCTTCTTCGCCACGCTCGCCGAACTGCGGGTACACGCCCGAACGGAGCACTATCTACCGCGCGATTCGAGTGCCCGCATTTTTGGCCATCAGTGCGAGTTCTGCTTCGCCGTTTTCGATTTTGAGCGAGGCCTTTTCATGCACCACGTTTCGCGACGCACGAAGGTAAAGACGCTGTACGAGTGCAAGCTTTGCGGGATGCTGTTTTCGAAGAAGTTTTGTCTCGCCCGGCACATGCAATCGGCACCGAACCATCTTTCGCGGTTAATTGTGGACGCGAGCATGAATGCGGATCGGGAGGAGGAGCGAGAGGAAGACTCCGAAGCATCCAATAGTGGTGCCCCAGTCGAGGGGATTGAGTCCGATCCACGGGTGCTGGAAGCGTTACAGCTGCACCGATCGGTTGAAGAGAAGGGACTGGAAAAGGTTGGCCATCTCGTGTGGTACCACTGCTGCTTTCCCAAATGCCCGGAAACGTTTACCAGCGAAGAGGCACTGCTGGCCCACGCACAGGACGAACATAACGGGCAGCGGCGAGAAAACTCGAACGAACGCAAGGAAGACACGAACGCGTGTCCTGCCTGCTGCAAATCATTCCAAACCCTTGCCAAGCTGATGTGGCATCGGGTGAAACGGTTCGTGCCGCGCAAATACCCCTGCAAACAGTGTGATAAAATATTTGACAAATGGTTGAAGCTCAAGATGCATGTGGAGCTCGAACACAGCGAAAAGCCGCCCAGCTTCCCGTGTCCCCAATGTGACAAAACGTTCGTCGTACGGTCCCGGCTGAAAGCTCATCTGCAAACGCACAGCGAGCGGAAGGATCATGCGTGCGATGTGTGCGGCGCCTCGTTCCACAACAAAGGGCTGTTGAAGCGTCACCGACGTGCCCTTCACTCCACCGAGCTGCTGTTCGAATGTAAGCACTGCTCGAAGAAGTTTGCCGTGGTGGAAAAGCTTAAAATTCATCAACGCGTTCATACGGGCGAGCGACCGTTCGAGTGTACGTTTTGCCCTCGAACTTTTCTACACTTTTCCGACCGGAAGCGGCATGAGATGGCTACGCACACGGGCGAACGGCCGTTCAAATGTAAGCTCTGTCCGGCGTCTTACATTCGAAATCGGGAGCTGAATTTGCACATGCAAAAGCACCGACTGGATAGTGGCGGGAAAAAGTTCACTAAGCAGTAG
- Protein Sequence
- MSKRRKISNVEEHDVGSSSEHHGNGERLLSKCCICSKHPKGGLLELCTSVESGLTIATIVEQVAGIKVKHVQKSICNACWTKIQAAYTIQKEIRGSECIEEQDVQDDYEIDDPLDAKAELHTREVDDYDEEHLENEDVFVKQEAVLPDEEYLIEYLEEHVYDNDEEQTQPAHGDDTDIAIEISATDKYEEPSEEYGKVTRVFKMPDTATIVSIAMHEQYRVVEVTGERCCGCSFVAQTRKELLQHSETVHCVEITDHGDYCPICFYKFASDQQLERHIQEFKLNKMFVCLRCNRFFNVRGQLFEHMERCREAGEMSAMENDPERKAVTIERIQEDDTECEEYYEQQEADAEEEHALPQRDGHTQNASDPRVMHRYKALFEEILSNEELSSPLTESDLNVQETQITAQHVFETFKYVRLRGLRCCGCSYTCYSSDLLLEHGKTSHPMEAAAAASSYPSCQLCWTRFPNETELVKHLCFFSTKQLFFCTVCDESFLNHESLRHHQLRNELHREQVHQRFQEAGIEMLEPAEPFVELDQPSIVDELGKLLAEKVTYRPKAIRCIPMPSEQFIKSKVEYNNYSTLTVEGEYCCGCARFFATLAELRVHARTEHYLPRDSSARIFGHQCEFCFAVFDFERGLFMHHVSRRTKVKTLYECKLCGMLFSKKFCLARHMQSAPNHLSRLIVDASMNADREEEREEDSEASNSGAPVEGIESDPRVLEALQLHRSVEEKGLEKVGHLVWYHCCFPKCPETFTSEEALLAHAQDEHNGQRRENSNERKEDTNACPACCKSFQTLAKLMWHRVKRFVPRKYPCKQCDKIFDKWLKLKMHVELEHSEKPPSFPCPQCDKTFVVRSRLKAHLQTHSERKDHACDVCGASFHNKGLLKRHRRALHSTELLFECKHCSKKFAVVEKLKIHQRVHTGERPFECTFCPRTFLHFSDRKRHEMATHTGERPFKCKLCPASYIRNRELNLHMQKHRLDSGGKKFTKQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00103874;
- 90% Identity
- -
- 80% Identity
- -