Basic Information

Insect: Anopheles maculipalpis
Gene Symbol: -
Assembly: GCA_943734865.1
Location: CALSEK010000293.1:11466-14494[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.4 4.5e+02 1.5 1.5 2 23 230 252 230 252 0.93

2 17 0.01 0.56 10.6 0.0 2 21 262 281 261 282 0.94

3 17 0.011 0.59 10.5 0.2 1 20 289 308 289 310 0.94

4 17 0.31 16 6.0 3.2 2 23 425 447 424 447 0.96

5 17 0.055 3 8.3 0.8 3 21 461 479 460 480 0.93

6 17 0.059 3.2 8.2 3.3 1 21 487 507 487 508 0.93

7 17 0.0072 0.39 11.1 0.8 3 23 588 609 587 609 0.96

8 17 2.7 1.5e+02 3.0 0.6 1 19 622 640 622 641 0.93

9 17 0.0025 0.14 12.5 2.6 1 22 652 673 652 677 0.93

10 17 0.016 0.87 10.0 0.9 2 23 741 765 740 765 0.84

11 17 3.3 1.7e+02 2.8 0.5 2 20 782 800 782 802 0.91

12 17 5.8e-05 0.0031 17.7 0.2 1 23 809 832 809 832 0.93

13 17 6.1e-07 3.3e-05 23.9 0.3 1 23 839 861 839 861 0.98

14 17 0.00018 0.0096 16.2 1.9 1 23 867 890 867 890 0.94

15 17 0.00044 0.024 14.9 2.9 1 23 896 918 896 918 0.98

16 17 0.43 23 5.5 3.0 1 23 924 947 924 947 0.91

17 17 8.4e-05 0.0045 17.2 1.5 1 23 953 975 953 975 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.4	4.5e+02	1.5	1.5	2	23	230	252	230	252	0.93
2	17	0.01	0.56	10.6	0.0	2	21	262	281	261	282	0.94
3	17	0.011	0.59	10.5	0.2	1	20	289	308	289	310	0.94
4	17	0.31	16	6.0	3.2	2	23	425	447	424	447	0.96
5	17	0.055	3	8.3	0.8	3	21	461	479	460	480	0.93
6	17	0.059	3.2	8.2	3.3	1	21	487	507	487	508	0.93
7	17	0.0072	0.39	11.1	0.8	3	23	588	609	587	609	0.96
8	17	2.7	1.5e+02	3.0	0.6	1	19	622	640	622	641	0.93
9	17	0.0025	0.14	12.5	2.6	1	22	652	673	652	677	0.93
10	17	0.016	0.87	10.0	0.9	2	23	741	765	740	765	0.84
11	17	3.3	1.7e+02	2.8	0.5	2	20	782	800	782	802	0.91
12	17	5.8e-05	0.0031	17.7	0.2	1	23	809	832	809	832	0.93
13	17	6.1e-07	3.3e-05	23.9	0.3	1	23	839	861	839	861	0.98
14	17	0.00018	0.0096	16.2	1.9	1	23	867	890	867	890	0.94
15	17	0.00044	0.024	14.9	2.9	1	23	896	918	896	918	0.98
16	17	0.43	23	5.5	3.0	1	23	924	947	924	947	0.91
17	17	8.4e-05	0.0045	17.2	1.5	1	23	953	975	953	975	0.99

Sequence Information

Coding Sequence: ATGTCGAAACGTAGAAAAATCTCTAACGCGGATATGAATGAAGTTGCATCCACGTCCGAACACCACGGTGACGGCGAAAGCATCCACACAAAATGCTGTATCTGTTCCAAACATCCGAAGGGCAGAAGCTTGCTCGAACTTTGTACGGTTGTGGAAAGCGACCGAACCATTGCTTCCATCGTCGAGCAGGTGGCCGGCATTAAGATAAAACATGTTCAAAAAAGCATTTGCAATGCTTGCTGGACAAAGATACAGGCTGCGTACACAATACAGAAGGAAATTAGAGACTCCGAATGTATAGAAGAACAGGACATGCTGGATGATTATGAGCTTGACGAACAGCTCGATTTTAAGGATGAATTCAACACAAAACACACTGATGACTACGACGAGGATCAGGTGGAAAATGCGGAAGACGTCATCGTCAAGCAGGAAACTGCACACCCCGACGATGAATATGTAATCGAATATTTGGAAGAAAATGTGTACGATAACGACGAAGAACAAGGCCGGCCTGCAAATGACAACGATCCAGACATAGCGATTGAAATATCAGCTAATGAAACGTACGAGGAACCAACCGAGGAGTACGGTAAAGTGACGCGCGTATTTAAAATGCCCGTTGCGGCAACGATCGTCAGCATTACGATGCACGATCAGTACCGCGTAGTTGAGGTTACGGGAGAACGTTGCTGTGGCTGTAGCTTTGTGGCCCAAACACGCAAAGAACTGTTGCAACATTCGGAAACGGTTCACTGCGTTGAAATTAACGATCACGGAGACTATTGCCCGATTTGTTTCTACAAGTTTGCGACGGATCAGGAGCTCGAGCAACACATCCAAGAGTTTAAGGCGAACAAGATGTATGTCTGTTTGCGTTGCAACTATTTCTTTAACGTGCGTGGCCATCTGATCGATCATATTGCGAGCTGTTACGAAGCTGGTGAGACGTCGTCAGCAACGGGAAATGGTTCGGTAACAATCGAACGTATCTCGAAGGAGGAGGAGGATGAAGATGACGAGTATTATCTGCAACAGGATGCAGCGGATGCAGAAGATGAACAAATGCCGTCACAATCGGATGGAGGCGGTCACACACAAAATGCATCGGATCCGCGTGTGATGCACCGATATAGAGCCCTGTTCGAGGAGATACTGTCGAACGACCAGCTATCGAGCCCGCTAACCGAATTGGAACTTAACGTCCAGGAAATACAAATAACTGCCCAACATGTGTTCGAAACATTCAAGTATGTCCGGTTACGTGGCTTACGTTGTTGTGGATGCTCTTACACCTGCTATTCAAGCGCTCTCCTTCTAGAGCACGGAAAAACAAGTCATCCGATGATGGAAAGCGGCGGCGCTGTTGGTAACCCATCCTGCCAGCTGTGCTGGACCCGGTTCCCAAACGAAACGGAACTTGTAAAGCATTTGTGCTTTTTCACCACCAAACAGCTGTTCTTCTGTACGGTTTGTGACGAATCGTTCCTCAACCACGAAAGCTTACGCCACCATCAGCTGCACAACGAACAACACCGGGACCAGTTGAACCAACAGTTCCAACAGGCCGGTATCGAAATGCTCGAACCGTTTGTCGAACTTGATCAACCACCGATCGTTGACGAGTTGGGAAAATTGTTGGCCGAAAAGGTTAGCTACAGACCTAAAATAATACGCTGTATTCCGATGCCGGCCACACGATTCATAAAGAACAGGACAGAGTACAACAACTACAGCACACTTACCGTTGTGGGTGAGTATTGCTGTGGCTGTGCCAAATTCTTCGATACACTCGCCGAACTCCGGGTACACGCCAAAACGGAACACTATCTACCGCTTGACTCGAGTGCCCAGCTTTTCGGTCATCAGTGTGAATTCTGTTATGCCGTTTTTGATTACGAGCGCGGACTTTTTATGCACAACGCTTGCCGTCGCACGAAGGAAAAAACGCTACATGAGTGCAAGCTTTGTGGGATGCTTTTTTCGAAAAAGTTTTGTCTCGCCCGGCACATGCAATCGGCACCGAACCATCTGTCGCGGTTAATTGTCGATGCAAACCTTAAGGTGGATCGGGATGAGGAACGAGAGGAAGATTCGGAGGCATCCAGCAGCGCACCAGTCGAAGCAATTGAATCGGATCCACGTGTACTGGAAGCGTTACAACTACACCGTTCGGTTGAAGAGAAAGGCTTGGAAAGGGTTGGCCATCTCGTGTGGTATCACTGTTGCTTTCCGAAATGTCCGGAAACGTTTACCAGTGAGGAAGCGCTGCTAGCTCACGCCCAGGACGAGCACAATGGGCAGCGGCGTGAAAACAACCACGAACGTAAGGAAGATACGAACGTGTGTCCTGCCTGCTGTAAATCATTCCAAACCTTGGCCAAGCTGATGTGGCATCGAGTGAAACGGTTTGTTCCGCGTAAATACCCCTGCAAACAGTGTGATAAAATATTCAACCAATGGGTAAAGCTAAAGATGCACGTAGAGCTCGAACACAACGGAACACCGCCCAACTTCCCCTGCCCACAGTGTGGCAAATCGTTCATTGTACGGTCGCGGCTGAAAGCTCACCTAAAAACGCACAGCGAACGGAAAGAACATGCGTGCGACGTGTGTGATGCTTCCTTTCACAATAAGGGACTACTGAAGCGTCATCGTCGGGCCCTACACTCCACCGAACTACTGTTCGAGTGTAAGCACTGTTCGAAAAAGTTTGCCGTAGTGGAaaagtttaaaattcatcaacgtgtacatactggcgaacggccgttcgagtgtacattctgtccacgaacgtttcTTCACTTTTCCGACCGCAAGCGGCACGAGATGGCTACCCACACCGGGGAACGACCGTTCAAATGTAAGCTCTGTACGGCGTCGTACATTCGCAACAGGGAGCTGAATTTGCACATGCAAAAACATCGAGTGGATGGTAGCGGGAAAAAGTCCATTAAACAGTAA
Protein Sequence: MSKRRKISNADMNEVASTSEHHGDGESIHTKCCICSKHPKGRSLLELCTVVESDRTIASIVEQVAGIKIKHVQKSICNACWTKIQAAYTIQKEIRDSECIEEQDMLDDYELDEQLDFKDEFNTKHTDDYDEDQVENAEDVIVKQETAHPDDEYVIEYLEENVYDNDEEQGRPANDNDPDIAIEISANETYEEPTEEYGKVTRVFKMPVAATIVSITMHDQYRVVEVTGERCCGCSFVAQTRKELLQHSETVHCVEINDHGDYCPICFYKFATDQELEQHIQEFKANKMYVCLRCNYFFNVRGHLIDHIASCYEAGETSSATGNGSVTIERISKEEEDEDDEYYLQQDAADAEDEQMPSQSDGGGHTQNASDPRVMHRYRALFEEILSNDQLSSPLTELELNVQEIQITAQHVFETFKYVRLRGLRCCGCSYTCYSSALLLEHGKTSHPMMESGGAVGNPSCQLCWTRFPNETELVKHLCFFTTKQLFFCTVCDESFLNHESLRHHQLHNEQHRDQLNQQFQQAGIEMLEPFVELDQPPIVDELGKLLAEKVSYRPKIIRCIPMPATRFIKNRTEYNNYSTLTVVGEYCCGCAKFFDTLAELRVHAKTEHYLPLDSSAQLFGHQCEFCYAVFDYERGLFMHNACRRTKEKTLHECKLCGMLFSKKFCLARHMQSAPNHLSRLIVDANLKVDRDEEREEDSEASSSAPVEAIESDPRVLEALQLHRSVEEKGLERVGHLVWYHCCFPKCPETFTSEEALLAHAQDEHNGQRRENNHERKEDTNVCPACCKSFQTLAKLMWHRVKRFVPRKYPCKQCDKIFNQWVKLKMHVELEHNGTPPNFPCPQCGKSFIVRSRLKAHLKTHSERKEHACDVCDASFHNKGLLKRHRRALHSTELLFECKHCSKKFAVVEKFKIHQRVHTGERPFECTFCPRTFLHFSDRKRHEMATHTGERPFKCKLCTASYIRNRELNLHMQKHRVDGSGKKSIKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108602;
90% Identity: -
80% Identity: -