Basic Information

Insect: Anopheles stephensi
Gene Symbol: ham
Assembly: GCA_013141755.1
Location: CM023249.1:81412378-81457455[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 7.2 4.1e+02 1.5 2.5 2 23 303 325 303 326 0.92

2 9 0.00036 0.021 15.0 0.1 1 23 332 355 332 355 0.96

3 9 2.4e-09 1.4e-07 31.3 0.9 1 23 361 383 361 384 0.96

4 9 1.8e-06 0.0001 22.3 1.7 1 23 390 412 390 412 0.95

5 9 1.7e-05 0.001 19.2 5.9 1 23 418 440 418 440 0.99

6 9 0.0042 0.24 11.7 1.3 2 21 448 467 447 468 0.95

7 9 2.1e-09 1.2e-07 31.5 1.1 1 23 1026 1048 1026 1048 0.99

8 9 1.9e-06 0.00011 22.2 1.6 1 23 1054 1077 1054 1077 0.97

9 9 0.00016 0.0095 16.1 6.7 1 23 1083 1105 1083 1105 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	7.2	4.1e+02	1.5	2.5	2	23	303	325	303	326	0.92
2	9	0.00036	0.021	15.0	0.1	1	23	332	355	332	355	0.96
3	9	2.4e-09	1.4e-07	31.3	0.9	1	23	361	383	361	384	0.96
4	9	1.8e-06	0.0001	22.3	1.7	1	23	390	412	390	412	0.95
5	9	1.7e-05	0.001	19.2	5.9	1	23	418	440	418	440	0.99
6	9	0.0042	0.24	11.7	1.3	2	21	448	467	447	468	0.95
7	9	2.1e-09	1.2e-07	31.5	1.1	1	23	1026	1048	1026	1048	0.99
8	9	1.9e-06	0.00011	22.2	1.6	1	23	1054	1077	1054	1077	0.97
9	9	0.00016	0.0095	16.1	6.7	1	23	1083	1105	1083	1105	0.99

Sequence Information

Coding Sequence: ATGGTCGATATCGAATTAATGATGCCAGGCATCAGTGGCGACGAATCGGACGCATCCCGTGGACTACCCGTCAATCTAGAAGTGCCTCCAGGGCTGCAGGTGGTACCGATGAGCAAGCATCACGATCACGGACCGGCAGACTTCAGCTTGCCCACATCCCTGCCTCATCACCTTCTACCCACCGCCGATGATGTTCGCGAGCGGCTAAAGCTCCAGAGTGCGGAACAGTTCCTGCTACAGATGGCACGGCTAcagcgaccaccaccaccagatcTGGACATCCAGACGGGGTCGGTCGTGGCGCTCAAAACCATCCCCAAGGGCACCCAGTACGGACCGTTCGTTGGCAAGCTGCTGCGGGAACCGATGGATCGACGGTTCGCTTGGGAGGTGATAGATGTAGATATCCGAGGCTGGCTGGATGCAACAGTCGAGCCGACGAACTGGATGAAACACATACGCTGCACCTCCAGCCCAACCGAAGCGAATGTGCAACACTTTCTCAAAGATGGTCATCTGTGGTACGAAGTGATATGTGATATCAGTCCCGGAAGGGAGCTGTTGCTGCGACCGAAGGTTCCTCTTCATCCGCGGGATGGGCAAGACGAGCGTGGCAGCGAACGTGGCTCGGGCGGTTCCCAGCACAGCGACAACTACGAGGACGAGTACAATACGTCGAACGATCTTGACTCTAGTCACAACAAGGAGCAGcaccgccatcatcatcacaacagtagcagcagtaacagCAGTGGCCGaagcagcaacggcagcagtaCCCGTGCGAACGGACACGGCCACCATCATCCGGCGGACGACAGTGGTAACGGAAGTGGCGAAccgcaccaacaccaccaccattcggACGTgaaggaggaggacgaggacgagCACGGCATTGACGCGCGGTGTGTCGTCTGTGATCGGCAGTGTCACGATATTGATCAGCTCGACGATCATCTCGTGATCTCGCACCATTATCCAAAGGACGCCTACAGGTGTGAGCTTTGTCCGAGGGCATACAGCTACAGACCATCGTTGCTGCGACACCGAGCGATCGTACACGGCGAGCTGCGACGGTTTCCGTGCGAGAACTGTCCCAAGGTTTTTACCGATCCCTCGAACTTGCAGCGCCACATCCGCACACATCACGTGGGAGCCCGTAGTCACGCGTGTCCCGAGTGTGGTAAGACGTTCGCCACCTCGTCCGGTCTCAAGCAGCACACGCACATCCACTCGTCAGTAAAGCCGTTCCAGTGCGAGGTGTGCTTCAAATCGTACACCCAGTTCTCCAACCTTTGCCGCCACCGGCGTATGCACGCTGACTGCCAGGTGCAGATAAAGTGTAACAAGTGTGGCGATAGCTTCAGCACTACGACGTCCCTCTCGAAGCACAAGCGTTTCTGTGACTCAACGGCAGTTACGCGAGCCTCACTACACTCCGGAGCTCATCCATCGCAACTGCGCCATTCGCACGATCCTTACCCACACGGACGCTCGATAGCGGGAGCGGGTCAACAGGgcagtgctggtggtggtagtggtacGGGAGGAGCATCCGCAGTTGGAGCCGGATCTGGTGCAGGACCACTTCACACTTTACCACCCGGCATGGCAACTCCACCGAATCCATTCCTTATGTTCCCGGGTGCACCGTTCTTCGCACCAGGGTTTAGACCATACCCGGGGATGCCCAGTATCTTCCCGCCGGCCCCAGGACAGGTTCCACAGTTTCCGTTGTCTTTCTTTCCAAAACCGGCGGCACCGGGCCCACTACCCGAACCGGAACGCAGAACTCCTTCACCATCTTCAAGACATCTTGGTCTGCTGGAAGGTTACGGGCAGCAATCGATGAAGATCTCACCACCGACCGGTGAGGAAGCGACCAACCATCTTCGCCCATCTCCGGCTCGTCCAATACCGGTTAGCTTCAACTCGGCGGCAGCAGCGGTGGCGCTACTGTCAGGATCTCCTGGTCCGCTAATGGGAAGTCATAGCCTCCCTGCTACGGAATCGGCCCCGGAGcgaggcaacaacaacaatcacatCAAGGAGAACAACAATCACAACCAGACGAATGGTACCAGTTCCTACGGTGGACCGCAGCAACAGTTGAGACGATCTTCAAGCCGCAGTAGCTCAGTAACTGCAGCGGCCACCGTTAAAGAAGAGCTGCATCGCGAGTCTTCAGATGCAGAGGAAGGAGATGCGGGAGTTTCAGCAATTCGGGTGAAGAATTTCTCTACACGATCGAAGAATTCCGTTGGAGAGCCGAGCAAGTCACCTGCTATGTCAGAGGATAGAAGTCAATCACAGCGTAGAAGAAGCCGCACTGTGGATGATGTTGATACGTCAGAATCCGAGGAGTTCTCGTCGGAGGCGAAGAAGGTTAAGAAGGAGGATGACTCAACCGGATCCGCAGAGCAACCCTTAGATCTGAGTCTTTCGAAGAAGCTTAAAAACGATGACACAGACGATGGTGGTGAAGGAGATGACGATAAAGATGCATCAGAGGAGGTAGAAAATCGTAGCTCAAACCGAAGTCCAACCCCGATCGAGGTGGCCAGTCCAAGATCCACACCGACCCCATCCGTTCCAACGCCCAACTCCTCGGACACACCGCACCAGGATCTCTCGCTGAGAGCGCGCGGACGGAACACTTCACCGAAAGCGGCATCGGCCTCTCCACTAGCAGATGCGTTCGCTTTACCAAGTCCCTCACCCTCACTGTCGCCGCGTCCATCACCCTCACCGTCCTCTCCGGGCGGTATGGTAGGATCCGGTCCTCACCACCAGCCCATCTCCTATCCACGACCGATCTATCCCTTTCTCCTCGAAGCGATGTGTCACGGAGGACCTGGCCCGATGGGAGGCTTTCAGCGACCAGCGTTCAGCTTCCTGGACTCACTAGAATCGAATCTGGATCTGCTAAAGCGTAGCCGTCAGTATATGCCTTCGAAAGCGTTTCACCAGGCAGCAATGATGCCACCGGGCTTCGGTGTTGGAGGAGCGCGGCCTCCCGGTGTACCGGGAGGACCCGGTGGACAGGTAgctcccgggaaggttaaagATCGATACTCGTGCAAGTACTGTGGCAAAGTGTTCCCGCGATCGGCCAACCTGACGCGGCATCTGCGTACCCACACGGGCGAACAGCCGTACAAGTGTCGGTACTGTGAGCGATCGTTCAGTATCTCGAGCAACCTGCAACGACATGTGCGGAATATCCACAACAAGGAGCGCCCGTTCAAGTGTCATCTGTGTGAGCGTTGTTTCGGCCAGCAGACGAATCTGGACCGGCATCTGAAGAAGCACGATGCGGATGCGTCTGGACTCGTGTTGGGTGATTCGCCCTCCTCCAACGAAGCAGAACGTGGGGAAGATGTGTTCTTCGATGAGATCCGTTCGTTTATGGGGAAGGTTACCTACTCGGGACCGGCGTCTCTGTTGCCTCCGGGGACACTGCCGGGAGCGTCAGACGTTGAGGCGGGTAAAGGGGATGGTGAGGATGGTGAGAACAGTGCGTCTGGAAGGAGGCGATATGGGCGAACGCTGGACGTGACTGGTGGGGATgatgaggaggaagaggaggaagaggatgaGGAGGAAGATGCAGCCAGCTGTGACGGTGAGAGTGATCTGATCAACATCGATTCGGACAAGGACACGATCAACAACAATGACACGATCGAGGTGTCTACTTAG
Protein Sequence: MVDIELMMPGISGDESDASRGLPVNLEVPPGLQVVPMSKHHDHGPADFSLPTSLPHHLLPTADDVRERLKLQSAEQFLLQMARLQRPPPPDLDIQTGSVVALKTIPKGTQYGPFVGKLLREPMDRRFAWEVIDVDIRGWLDATVEPTNWMKHIRCTSSPTEANVQHFLKDGHLWYEVICDISPGRELLLRPKVPLHPRDGQDERGSERGSGGSQHSDNYEDEYNTSNDLDSSHNKEQHRHHHHNSSSSNSSGRSSNGSSTRANGHGHHHPADDSGNGSGEPHQHHHHSDVKEEDEDEHGIDARCVVCDRQCHDIDQLDDHLVISHHYPKDAYRCELCPRAYSYRPSLLRHRAIVHGELRRFPCENCPKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKSYTQFSNLCRHRRMHADCQVQIKCNKCGDSFSTTTSLSKHKRFCDSTAVTRASLHSGAHPSQLRHSHDPYPHGRSIAGAGQQGSAGGGSGTGGASAVGAGSGAGPLHTLPPGMATPPNPFLMFPGAPFFAPGFRPYPGMPSIFPPAPGQVPQFPLSFFPKPAAPGPLPEPERRTPSPSSRHLGLLEGYGQQSMKISPPTGEEATNHLRPSPARPIPVSFNSAAAAVALLSGSPGPLMGSHSLPATESAPERGNNNNHIKENNNHNQTNGTSSYGGPQQQLRRSSSRSSSVTAAATVKEELHRESSDAEEGDAGVSAIRVKNFSTRSKNSVGEPSKSPAMSEDRSQSQRRRSRTVDDVDTSESEEFSSEAKKVKKEDDSTGSAEQPLDLSLSKKLKNDDTDDGGEGDDDKDASEEVENRSSNRSPTPIEVASPRSTPTPSVPTPNSSDTPHQDLSLRARGRNTSPKAASASPLADAFALPSPSPSLSPRPSPSPSSPGGMVGSGPHHQPISYPRPIYPFLLEAMCHGGPGPMGGFQRPAFSFLDSLESNLDLLKRSRQYMPSKAFHQAAMMPPGFGVGGARPPGVPGGPGGQVAPGKVKDRYSCKYCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKERPFKCHLCERCFGQQTNLDRHLKKHDADASGLVLGDSPSSNEAERGEDVFFDEIRSFMGKVTYSGPASLLPPGTLPGASDVEAGKGDGEDGENSASGRRRYGRTLDVTGGDDEEEEEEEDEEEDAASCDGESDLINIDSDKDTINNNDTIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00099174; iTF_00093643; iTF_00102537; iTF_00101118; iTF_00107167; iTF_00101843; iTF_00105309;
90% Identity: iTF_00101843;
80% Identity: -